In vitro photodynamic properties of chalcogenopyrylium analogues of the thiopyrylium antitumor agent AA1

Journal of Medicinal Chemistry

Volumn 45, Issue 23, 2002, Pages 5123-5135

  Brennan, Nancy K ^a   Hall, Jonathan P ^a   Davies, Sherry R ^c   Gollnick, Sandra O ^c   Oseroff, Allan R ^c   Gibson, Scott L ^b   Hilf, Russell ^b   Detty, Michael R ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 ANILINO) 4 (4 N,N DIMETHYLANILINO) 6 (4 N MORPHOLINOPHENYL)SELENOPYRYLIUM CHLORIDE; 2 (4 ANILINO) 4,6 BIS(4 N MORPHOLINOPHENYL)SELENOPYRYLIUM CHLORIDE; 2 (4 ANILINO) 4,6 BIS(4 N MORPHOLINOPHENYL)TELLUROPYRYLIUM CHLORIDE; 2 (4 ANILINO) 4,6 BIS(4 N MORPHOLINOPHENYL)THIOPYRYLIUM CHLORIDE; 2,4,6 TRIS(4 N MORPHOLINOPHENYL)SELENOPYRYLIUM CHLORIDE; 2,6 BIS(4 ANILINO) 4 (4 N MORPHOLINOPHENYL)SELENOPYRYLIUM CHLORIDE; 2,6 BIS(4 ANILINO) 4 (4 N,N DIMETHYLANILINO)SELENOPYRYLIUM CHLORIDE; ANTINEOPLASTIC AGENT; CHALCOGEN; CYTOCHROME C OXIDASE; DYE; OCTANOL; SELENIUM; SULFUR; TELLURIUM; UNCLASSIFIED DRUG; WATER;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IRRADIATION; MITOCHONDRION; PHOTODYNAMICS; PHOTOTOXICITY; REDUCTION;

ANILINE COMPOUNDS; ANIMALS; CHALCOGENS; COLORING AGENTS; DARKNESS; ELECTRON TRANSPORT COMPLEX IV; LETHAL DOSE 50; LIGHT; MICE; MITOCHONDRIA; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PYRANS; SELENIUM; SOLUBILITY; SULFUR; TELLURIUM; THIOPHENES; TUMOR CELLS, CULTURED;

EID: 0037038330     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020260m     Document Type: Article

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