QSAR study of ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl) pyrimidine-5-carboxylate: An inhibitor of Ap-1 and NF-/κB mediated gene expression based on support vector machines

Journal of Chemical Information and Computer Sciences

Volumn 43, Issue 4, 2003, Pages 1288-1296

  Liu, H X ^a   Zhang, R S ^a   Yao, X J ^a,c   Liu, M C ^a   Hu, Z D ^a,b   Fan, B T ^c  

^a LANZHOU UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

APPROXIMATION THEORY; ERROR ANALYSIS; GENES; INFORMATION ANALYSIS; MATHEMATICAL MODELS; MOLECULAR STRUCTURE; NITROGEN; QUANTUM THEORY; SYNTHESIS (CHEMICAL);

QUANTITIVE STRUCTURE-ACTIVITY RELATIONSHIPS (QSAR);

ORGANIC COMPOUNDS;

CARBOXYLIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; TRANSCRIPTION FACTOR AP 1;

ARTICLE; BIOLOGY; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; GENE EXPRESSION REGULATION; HUMAN; METHODOLOGY; PHYSIOLOGY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTUM THEORY; SENSITIVITY AND SPECIFICITY;

CARBOXYLIC ACIDS; COMPUTATIONAL BIOLOGY; DRUG DESIGN; GENE EXPRESSION REGULATION; HUMANS; NF-KAPPA B; PYRIMIDINES; PYRROLES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUANTUM THEORY; SENSITIVITY AND SPECIFICITY; TRANSCRIPTION FACTOR AP-1;

EID: 0043201408     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci0340355     Document Type: Article

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