Immunohistochemical study of brain-derived neurotrophic factor and its receptor, TrkB, in the hippocampal formation of schizophrenic brains

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 27, Issue 5, 2003, Pages 801-807

  Iritani, Shuji ^a   Niizato, Kazuhiro ^a   Nawa, Hiroyuki ^b   Ikeda, Kenji ^c   Emson, Piers C ^d  

^a TOKYO METROPOLITAN MATSUZAWA HOSPITAL   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

BDNF; Hippocampus; Immunohistochemistry; TrkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR;

ADULT; AGED; ARTICLE; CELL SHAPE; CONTROLLED STUDY; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PYRAMIDAL NERVE CELL; SCHIZOPHRENIA;

EID: 0043133769     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(03)00112-X     Document Type: Article

References (36)

1. Akbarian S., Potkin S.G., Kim J.J. Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch. Gen. Psychiatry. 52:1995;258-266.
2. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders. 4th ed. 1994;American Psychiatric Association, Washington, DC.
3. Angelucci F., Mathe A.A., Aloe L. Brain-derived neurotrophic factor and tyrosine kinase receptor TrkB in rat brain are significantly altered after haloperidol and risperidone administration. J. Neurosci. Res. 60:2000;783-794.
4. Ashe P.C., Chlan-Fourney J., Juorio A.V., Li X.M. Brain-derived neurotrophic factor (BDNF) mRNA in rats with neonatal ibotenic acid lesions of the ventral hippocampus. Brain Res. 956:2002;126-135.
5. Bernstein H.G., Braunewell K.H., Spilker C., Danos P., Baumann B., Funke S., Diekmann S., Gundelfinger E.D., Bogerts B. Hippocampal expression of the calcium sensor protein visinin-like protein-1 in schizophrenia. NeuroReport. 13:2002;393-396.
6. Bessho Y., Nakanishi S., Nawa H. Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells. Brain Res. Mol. Brain Res. 18:1993;201-208.
7. Black I.B. Trophic regulation of synaptic plasticity. J. Neurobiol. 41:1999;108-118.
8. Blochl A., Thoenen H. Localization of cellular storage compartments and sites of constitutive and activity-dependent release of nerve growth factor (NGF) in primary cultures of hippocampal neurons. Mol. Cell Neurosci. 7:1996;173-190.
9. Bogerts B. The neuropathology of schizophrenic diseases: historical aspects and present knowledge. Eur. Arch. Psychiatry Clin. Neurosci. 249(Suppl. 4):1999;IV/2-IV/13.
10. Cabelli R.J., Hohn A., Shatz C.J. Inhibition of ocular dominance column formation by infusion of NT-4/5 or BDNF. Science. 267:1995;1662-1666.
11. Chao M.V. Trophic factors: an evolutionary cul-de-sac or door into higher neuronal function? J. Neurosci. Res. 59:2000;353-355.
12. Chlan-Fourney J., Li X.-M., Juorio A.V., Ashe P., Boulton A.A. Differential regulation of brain derived neurotrophic factor (BDNF) mRNA in rat brain by chronic haloperidol, risperidone and clozapine treatment. Soc. Neurosci. Abs. 1998;295.4.
13. Eastwood S.L., Harrison P.J. Detection and quantification of hippocampal synaptophysin messenger RNA in schizophrenia using autoclaved, formalin-fixed, paraffin wax-embedded sections. Neuroscience. 93:1999;99-106.
14. Hsu S., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 29:1981;577-580.
15. Itami C., Mizuno K., Kohno T., Nakamura S. Brain-derived neurotrophic factor requirement for activity-dependent maturation of glutamatergic synapse in developing mouse somatosensory cortex. Brain Res. 857:2000;141-150.
16. Kang H., Schuman E.M. Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science. 267:1995;1658-1662.
17. Kang H., Welcher A.A., Shelton D., Schuman E.M. Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation. Neuron. 19:1997;653-1664.
18. Lorente De Nó R. Studies on the structure of the cerebral cortex: II. Continuation of the study of the ammonic system. J. Psychol. Neurol. 46:1934;113-177.
19. Linnarsson S., Bjorklund A., Ernfors P. Learning deficit in BDNF mutant mice. Eur. J. Neurosci. 9:1997;2581-2587.
20. McCaig C.D., Sangster L., Stewart R. Neurotrophins enhance electric field-directed growth cone guidance and directed nerve branching. Dev. Dyn. 217:2000;299-308.
21. Minichiello L., Korte M., Wolfer D., Kuhn R., Unsicker K., Cestari V., Rossi-Arnaud C., Lipp H.P., Bonhoeffer T., Klein R. Essential role for TrkB receptors in hippocampus-mediated learning. Neuron. 24:1999;401-414.
22. Nawa H., Bessho Y., Carnahan J., Nakanishi S., Mizuno K. Regulation of neuropeptide expression in cultured cerebral cortical neurons by brain-derived neurotrophic factor. J. Neurochem. 60:1993;772-775.
23. Nawa H., Pelleymounter M.A., Carnahan J. Intraventricular administration of BDNF increases neuropeptide expression in newborn rat brain. J. Neurosci. 14:1994;3751-3765.
24. Nawa H., Saito M., Nagano T. Neurotrophic factors in brain synaptic plasticity. Crit. Rev. Neurobiol. 11:1997;91-100.
25. Schuman E.M. Neurotrophin regulation of synaptic transmission. Curr. Opin. Neurobiol. 9:1999;105-109.
26. Stoop R., Poo M.M. Synaptic modulation by neurotrophic factors: differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor. J. Neurosci. 16:1996;3256-3264.
27. Takahashi M., Shirakawa O., Toyooka K., Kitamura N., Hashimoto T., Maeda K., Koizumi S., Wakabayashi K., Takahashi H., Someya T., Nawa H. Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients. Mol. Psychiatry. 5:2000;293-300.
28. Takei N., Sasaoka K., Inoue K., Takahashi M., Endo Y., Hatanaka H. Brain-derived neurotrophic factor increases the stimulation-evoked release of glutamate and the levels of exocytosis-associated proteins in cultured cortical neurons from embryonic rats. J. Neurochem. 68:1997;370-375.
29. Tamminga C.A., Thaker G.K., Buchanan R., Kirkpatrick B., Alphs L.D., Chase T.N., Carpenter W.T. Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome. Arch. Gen. Psychiatry. 49:1992;522-530.
30. Thoenen H. Neurotrophins and neuronal plasticity. Science. 270:1995;593-598.
31. Thome J., Foley P., Riederer P. Neurotrophic factors and the maldevelopmental hypothesis of schizophrenic psychoses. J. Neural Transm. 105:1998;85-100.
32. Toru M., Kurumaji A., Ishimaru M. Excitatory amino acids: implications for psychiatric disorders research. Life Sci. 55:1994;1683-1699.
33. Toyooka K., Asama K., Watanabe Y., Muratake T., Takahashi M., Someya T., Nawa H. Decreased levels of brain-derived neurotrophic factor in serum of chronic schizophrenic patients. Psychiatry Res. 110:2002;249-257.
34. Waddington J.L., Lane A., Scully P.J., Larkin C., O'Callaghan E. Neurodevelopmental and neuroprogressive processes in schizophrenia. Antithetical or complementary, over a lifetime trajectory of disease? Psychiatr. Clin. North Am. 21:1998;123-149.
35. Weinberger D.R. Cell biology of the hippocampal formation in schizophrenia. Biol. Psychiatry. 45:1999;395-402.
36. Zamboni L., De Martino C. Buffered picric acid formaldehyde: a new rapid fixative for electron microscopy. J. Cell Biol. 35:1967;148.