The amount of sonic hedgehog in mutliple sclerosis white matter is decreased and cleavage to the signaling peptide is deficient

Multiple Sclerosis

Volumn 9, Issue 4, 2003, Pages 362-371

  Mastronardi, Fabrizio G ^a   DaCruz, Luis A G ^a   Wang, Huimin ^a   Boggs, Joan ^a   Moscarello, Mario A ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Multiple sclerosis; Myelin basic protein; Neurodegenerative disease; Sonic hedgehog

Indexed keywords

MYELIN; SIGNAL PEPTIDE;

ADULT; AGED; ANIMAL CELL; ARTICLE; BRAIN; BRAIN HOMOGENATE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; GRAY MATTER; HEDGEHOG; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IN VITRO STUDY; MULTIPLE SCLEROSIS; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PURIFICATION; VICTIM; WESTERN BLOTTING; WHITE MATTER;

ACIDS; ADULT; AGED; AGED, 80 AND OVER; BRAIN; CELL FRACTIONATION; HEDGEHOG PROTEINS; HUMANS; MIDDLE AGED; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; MYELIN SHEATH; NERVE FIBERS, MYELINATED; NEURONS; OLIGODENDROGLIA; SIGNAL TRANSDUCTION; SOLUBILITY; TRANS-ACTIVATORS;

EID: 0043125614     PISSN: 13524585     EISSN: None     Source Type: Journal    
DOI: 10.1191/1352458503ms924oa     Document Type: Article

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