Impact of blood pressure and insulin on the relationship between body fat and left ventricular structure

European Heart Journal

Volumn 24, Issue 16, 2003, Pages 1500-1505

  Karason, Kristjan ^a   Sjöström, Lars ^a   Wallentin, Ingemar ^a   Peltonen, Markku ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Blood pressure; Echocardiography; Hypertrophy; Insulin; Obesity

Indexed keywords

GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ADULT; ARTICLE; BLOOD PRESSURE; BODY COMPOSITION; BODY FAT; BODY WEIGHT; CONTROLLED STUDY; ECHOCARDIOGRAPHY; FEMALE; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HUMAN; HYPERTENSION; INSULIN BLOOD LEVEL; LEAN BODY WEIGHT; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OBESITY; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE;

ADIPOSE TISSUE; ADULT; BLOOD PRESSURE; BODY COMPOSITION; CARDIOMYOPATHIES; FEMALE; HEART VENTRICLES; HUMANS; INSULIN; MALE; MIDDLE AGED; MYOCARDIUM; OBESITY; SKINFOLD THICKNESS;

EID: 0042970651     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0195-668X(03)00312-9     Document Type: Article

References (42)

1. Eckel RH. Obesity and heart disease: a statement for healthcare professionals from the Nutrition Committee, American Heart Association. Circulation 1997;96:3248-50.
2. Lauer MS, Anderson KM, Kannel WB et al. The impact of obesity on left ventricular mass and geometry. The Framingham Heart Study. Jama 1991;266:231-6.
3. Hammond IW, Devereux RB, Alderman MH et al. Relation of blood pressure and body build to left ventricular mass in normotensive and hypertensive employed adults. J Am Coll Cardiol 1988;12:996-1004.
4. Messerti FH, Sundgaard-Riise K, Reisin ED et al. Dimorphic cardiac adaptation to obesity and arterial hypertension. Ann Intern Med 1983;99:757-61.
5. Lauer MS, Anderson KM, Levy D. Separate and joint influences of obesity and mild hypertension on left ventricular mass and geometry: the Framingham Heart Study. J Am Coll Cardiol 1992;19:130-4.
6. Koren MJ, Devereux RB, Casale PN et al. Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med 1991;114:345-52.
7. Verdecchia P, Schillaci G, Borgioni C et al. Adverse prognostic significance of concentric remodeling of the left ventricle in hypertensive patients with normal left ventricular mass. J Am Coll Cardiol 1995;25:871-8.
8. Alexander JK, Dennis EW, Smith WG et al. Blood volume, cardiac output, and distribution of systemic blood flow in extreme obesity. Cardiovascular Research Center Bulletin 1962-63;1:39-44.
9. Kannel WB, Brand N, Skinner JJ Jr, et al. The relation of adiposity to blood pressure and development of hypertension. The Framingham study. Ann Intern Med 1967;67:48-59.
10. Chiang BN, Perlman LV, Epstein FH. Overweight and hypertension. A review. Circulation 1969;39:403-21.
11. Modan M, Halkin H, Almog S et al. Hyperinsulinemia: A link between hypertension obesity and glucose intolerance. J Cin Invest 1985;75:809-17.
12. Kannel WB, Gordon T, Castelli WP. Obesity, lipids, and glucose intolerance. The Framingham Study. Am J Clin Nutr 1979;32:1238-12345.
13. Sjöström CD, Lissner L, Sjöstrom L. Relationships between changes in body composition and changes in cardiovascular risk factors: the SOS Intervention Study. Swedish Obese Subjects. Obes Res 1997;5:519-30.
14. Sasson Z, Rasooly Y, Bhesania T et al. Insulin resistance is an important determinant of left ventricular mass in the obese. Circulation 1993;88:1431-6.
15. Urbina EM, Gidding SS, Bao W et al. Association of fasting blood sugar level, insulin level, and obesity with left ventricular mass in healthy children and adolescents: The Bogalusa Heart Study. Am Heart J 1999;138:122-7.
16. Sjöström L, Larsson B, Backman L et al. Swedish obese subjects (SOS). Recruitment for an intervention study and a selected description of the obese state. Int J Obes Relat Metab Disord 1992;16:465-79.
17. Kvist H, Chowdhury B, Grangärd U et al. Total and visceral adipose-tissue volumes derived from measurements with computed tomography in adult men and women: predictive equations. Am J Clin Nutr 1988;48:1351-61.
18. Pichard C, Kyle UG, Bracco D et al. Reference values of fat-free and fat masses by bioelectrical impedance analysis in 3393 healthy subjects. Nutrition 2000;16:245-54.
19. Laakso M. How good a marker is insulin level for insulin resistance? Am J Epidemiol 1993;137:959-65.
20. Sahn DJ, DeMaria A, Kissio J et al. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 1978;58:1072-83.
21. Devereux RB, Alonso DR, Lutas EM et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol 1986;57:450-8.
22. Hense HW, Gneiting B, Muscholl M et al. The associations of body size and body composition with left ventricular mass: impacts for indexation in adults. J Am Coll Cardiol 1998;32:451-7.
23. Kuch B, Gneiting B, Doring A et al. Indexation of left ventricular mass in adults with a novel approximation for fat-free mass. J Hypertens 2001;19:135-42.
24. Messerli FH. Cardiovascular effects of obesity and hypertension. Lancet 1982;1:1165-8.
25. Karlsson C, Lindell K, Ottosson M et al. Human adipose tissue expresses angiotensinogen and enzymes required for its conversion to angiotensin II. J Clin Endocrinol Metab 1998;83:3925-9.
26. Engeli S, Negrel R, Sharma AM. Physiology and pathophysiology of the adipose tissue renin-angiotensin system. Hypertension 2000;35:1270-7.
27. Dzau VJ. The role of mechanical and humoral factors in growth regulation of vascular smooth muscle and cardiac myocytes. Curr Opin Nephrol Hypertens 1993;2:27-32.
28. Alpert MA, Lambert CR, Panayiotou H et al. Relation of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss. Am J Cardiol 1995;76:1194-7.
29. Sharp SD, Williams RR. Fasting insulin and left ventricular mass in hypertensives and normotensive controls. Cardiology 1992;81:207-12.
30. Verdecchia P, Reboldi G, Schillaci G et al. Circulating insulin and insulin growth factor-1 are independent determinants of left ventricular mass and geometry in essential hypertension. Circulation 1999;100:1802-7.
31. Ilercil A, Devereux RB, Roman MJ et al. Associations of insulin levels with left ventricular structure and function in American Indians: the strong heart study. Diabetes 2002;51:1543-7.
32. Rheeder P, Stolk RP, Mosterd A et al. Insulin resistance syndrome and left ventricular mass in an elderly population (The Rotterdam Study). Am J Cardiol 1999;84:233-6 A9.
33. Galvan AQ, Galetta F, Natali A et al. Insulin resistance and hyperinsulinemia: No independent relation to left ventricular mass in humans. Circulation 2000;102:2233-8.
34. Malmqvist K, Isaksson H, Ostergren J et al. Left ventricular mass is not related to insulin sensitivity in never-treated primary hypertension. J Hypertens 2001;19:311-7.
35. Costa CH, Batista MC, Moises VA et al. Serum insulin levels, 24-hour blood pressure profile, and left ventricular mass in nonobese hypertensive patients. Hypertension 1995;26:1085-8.
36. Ohya Y, Abe I, Fujii K et al. Hyperinsulinemia and left ventricular geometry in a work-site population in Japan. Hypertension 1996;27:729-34.
37. Sundstrom J, Lind L, Nystrom N et al. Left ventricular concentric remodeling rather than left ventricular hypertrophy is related to the insulin resistance syndrome in elderly men. Circulation 2000;101:2595-600.
38. Despres JP, Lamarche B, Mauriege P et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med 1996;334:952-7.
39. Hill DJ, Milner RD. Insulin as a growth factor. Pediatr Res 1985;19:879-86.
40. Ito H, Hiroe M, Hirata Y et al. Insulin-like growth factor-I induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes. Circulation 1993;87:1715-21.
41. Holmang A, Yoshida N, Jennische E et al. The effects of hyperinsulinaemia on myocardial mass, blood pressure regulation and central haemodynamics in rats. Eur J Clin Invest 1996;26:973-8.
42. Reaven GM, Lithell H, Landsberg L. Hypertension and associated metabolic abnormalities-the role of insulin resistance and the sympathoadrenal system. N Engl J Med 1996;334:374-81.