Expression of inducible nitric oxide synthase in paired neoplastic and non-neoplastic primary prostate cell cultures and prostatectomy specimen

Urologic Oncology: Seminars and Original Investigations

Volumn 21, Issue 2, 2003, Pages 117-122

  Wang, Jianzhou ^a,c   Torbenson, Michael ^a,d   Wang, Qi ^a   Ro, Jae Y ^b   Becich, Michael ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Inducible nitric oxide synthase; Nitric oxide; Prostate; Prostate adenocarcinoma

Indexed keywords

BETA ACTIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRIC OXIDE SYNTHASE; NOS2A PROTEIN, HUMAN;

ANGIOGENESIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROSTATECTOMY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH; ADENOCARCINOMA; BIOSYNTHESIS; CHEMISTRY; COMPARATIVE STUDY; CULTURE TECHNIQUE; MALE; METABOLISM; ONCOGENESIS AND MALIGNANT TRANSFORMATION; PATHOLOGY; PROSTATE; PROSTATE TUMOR;

ADENOCARCINOMA; CELL CULTURE TECHNIQUES; HUMANS; MALE; NEOPLASTIC PROCESSES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROSTATE; PROSTATECTOMY; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0042887196     PISSN: 10781439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1078-1439(02)00208-9     Document Type: Article

References (42)

1. Moncada S, Palmer RJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991;43:109-42.
2. Nathan CF, Xie QW. Nitric oxide synthases: rolles, tolls, and controls. Cell 1994;78:915-8.
3. Vallance P, Collier J, Moncada S. Effects of endothelium derived nitric oxide on peripheral arteriolar tone in man. Lancet 1989;2:997-1000.
4. Schuman EM, Madison DV. A require for the intercellular messenger nitric oxide in long-term potentiation. Science 1991;254:1503-6.
5. Desai KM, Sessa WC, Vane JR. Involvement of nitric oxide in the reflex relaxation of stomach to accommodate food or fluid. Nature 1991;351:477-99.
6. Bult H, Boechxstaens GE, Pelckmans PA, Joraens FH, Van Maercke YM, Herman AG. Nitric oxide as an inhibitory non-andrenergic, non-cholinergic neurotransmitter. Nature 1990;345:346-7.
7. Stuehr DJ, Marletta MA. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Pro Natl Acad Sci USA 1985;82:7738-42.
8. Hibbs JR Jr, Westenfelder C, Taintor RR, et al. Evidence for cytokine-inducible nitric synthesis from L-arginine in patients receiving interleukin-2 therapy. J Clin Invest 1992;89:867-77.
9. Oshima H, Bartsch H. Chronic inflammations and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenic process. Mutat Res 1994;305:241-52.
10. Liu RH, Hotchkiss JH. Potential genotoxicity of chronically elevated nitric oxide: a review. Mutat Res 1995;339:73-89.
11. Nguyen T, Brunson D, Crespi CL, Penman BW, Wishnok JS, Tannenbaum SR. DNA damage and mutation in human cells exposed to nitric oxide in vitro. Proc Natl Acad Sci USA 1992;89:3030-4.
12. Kim YM, Talanian R, Billiar T. Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. J Bio Chem 1997;272:31138-48.
13. Binder C, Schulz M, Hiddemann W, Oellerich M. Induction of inducible nitric oxide synthase is an essential part of tumor necrosis factor-α-induced apoptosis in MCF-7 and other epithelial tumor cells. Lab Invest 1999;79:1703-11.
14. Li J, Bombeck C, Yang S, Kim YM, Billiar T. Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes. J Bio Chem 1999;274:17325-33.
15. Umansky V, Ushmorov A, Ratter F. Nitric oxide-mediated apoptosis in human breast cancer cells requires changes in mitochondrial functions and is independent of CD95 (APO-1/Fas). Int J Oncol 2000;16:109-17.
16. Kim YM, Kim TH, Chung HT, Talanian R, Yin XM, Billiar T. Nitric oxide prevents tumor necrosis factor α-induced rat hepatocyte apoptosis by the interruption of mitochondrial apoptotic signaling through s-nitrosylation of caspase-8. Hepatology 2000;32:770-8.
17. Ziehe M, Morbidelli E, Masini E, Granger H, Geppetti P, Ledda F. Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules. Biochem Biophys Res Commun 1993;192:1198-203.
18. Kennovin GD, Hirst DG, Stratford MRL, Flitney FW. Inducible nitric oxide synthase is expressed in tumor-associated vasculature: inhibition retards tumor growth in vivo. In: Moncada S, Feelisch M, Busse R, Higgs EA, editors. Biology of nitric oxide, part 4: enzymology, biochemistry and immunology. London: Portland Press, 1994. pp. 473-9.
19. Jenkins DC, Charles JG, Thomsen LL, et al. Roles of nitric oxide in tumor growth. Proc Natl Acad Sci USA 1995;92:4392-6.
20. Ziehe M, Morbidelli E, Masini E, Amerini S, et al. Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P. J Clin Invest 1994;94:2036-44.
21. Fukumura D, Yuan F, Endo M, Jain RK. Role of nitric oxide in tumor microcirculation, blood flow, vascular permeability, and leukocyte-endothelial interactions. Am J Pathol 1997;150:713-25.
22. Edwards P, Cendan JC, Topping DB, et al. Tumor cell nitric oxide inhibits cell growth in vitro, but stimulates tumorigenesis and experimental lung metastasis in vivo. J Surg Res 1996;63:49-52.
23. Lejeune P, Lagadec P, Onier N, Pinard D, Ohshima H, Jeannin JF. Nitric oxide involvement in tumor-induced immunosuppression. J Immunol 1994;152:5077-83.
24. Rajnakova A, Goh P, Chan S, Ngoi SS, Slponat A, Moochhala S. Expression of differential nitric oxide synthase isoforms in human normal gastric mucosa and gastric cancer tissue. Carcinogenesis 1997;18:1841-5.
25. Moochhala S, Chhatwal V, Chan S, Ngoi SS, Chia YW, Rauff A. Nitric oxide synthase activity and expression in human colorectal cancer. Carcinogenesis 1996;17:1171-4.
26. Doi K, Akaike T, Horie H, Noguchi Y, Fujii S, Beppu T, Ogawa M, Maeda H. Excessive production of nitric oxide in rat solid tumor and its implication in rapid tumor growth. Cancer 1996;77:1598-604.
27. Thomsen LL, Miles DW, Happerfield L, Bobrow LG, Knowles RG, Moncada S. Nitric oxide synthase activity in human breast cancer. Br J Cancer 1995;72:41-4.
28. Krill D, Shuman M, Thompson MT, Becich MJ, Strom SC. A simple method for the isolation and culture of epithelial and stromal cells from benign and neoplastic prostates. Urology 1997;49:981-8.
29. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Ann Biochem 1987;162:156.
30. Brenner CA, Tam AW, Nelson PA. Message amplification phenotyping (MAPPing): a technique to simultaneously measure multiple mRNAs from small numbers of cells. Biotechniques 1989;7:1096-101.
31. Humphrey PA, Zhu X, Zarnegar R, et al. Hepatocyte growth factor and its receptor (c-MET) in prostatic carcinoma. Am J Pathol 1995;147:386.
32. Kroncke KD, Fehsel K, Kolb-Bachofen V. Inducible nitric oxode synthase in human disease (review). Clin Exp Immunol 1998;113:147-56.
33. Geller D, Billiar T. Molecular biology of nitric oxide synthases. Cancer Metastasis Rev 1998;17:7-23.
34. Kojima M, Morisaki T, Tsukahara Y, et al. Nitric oxide synthase expression and nitric oxide production in human colon carcinoma tissue. J Surg Oncol 1999;70:222-9.
35. Ambs S, Merriam WG, Bennett WP, et al. Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. Cancer Res 1998;58:334-41.
36. Tanaka H, Kijima H, Tokunaga T, et al. Frequent expression of inducible nitric oxide synthase in esophageal squamous cell carcinomas. Int J Oncol 1999;14:1069-73.
37. Vickers SM, MacMillan-Crow LA, Green M, Ellis C, Thompson JA. Association of increased immunostaining for inducible nitric oxide synthase and nitrotyrosine with fibroblast growth factor transformation in pancreatic cancer. Arch Surg 1999;134:245-51.
38. Gallo O, Masini E, Morbidelli L, et al. Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer. J Natl Cancer Inst 1998;90:587-96.
39. Thomsen LL, Sargent JM, Williamson CJ, Elgie AW. Nitric oxide synthase activity in fresh cells from ovarian tumour tissue: relationship of enzyme activity with clinical parameters of patients with ovarian cancer. Biochem Pharmacol 1998;56:1365-70.
40. Tschugguel W, Schneeberger C, Unfried G, et al. Expression of inducible nitric oxide synthase in human breast cancer depends on tumor grade. Breast Cancer Res Treat 1999;56:145-51.
41. Fujimoto H, Ando Y, Yamashito T, et al. Nitric oxide synthase activity in human lung cancer. Jpn J Cancer Res 1997;88:1190-8.
42. Rao CV, Kavamori T, Hamid R, Reddy BS. Chemoprevention of colonic aberrant crypt foci by an inducible nitric oxide synthase-selective inhibitor. Carcinogenesis 1999;20:641-4.