Expression of differential nitric oxide synthase isoforms in human normal gastric mucosa and gastric cancer tissue

Carcinogenesis

Volumn 18, Issue 9, 1997, Pages 1841-1845

  Rajnakova, Andrea ^a   Goh, Peter M Y ^a   Chan, Steven T F ^a   Ngoi, Sing Shang ^a   Alponat, Ahmet ^a   Moochhala, Shabbir ^a  

^a NATIONAL UNIVERSITY HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ISOENZYME; NITRIC OXIDE SYNTHASE;

ADULT; AGED; ANTIBODY SPECIFICITY; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; STOMACH CANCER; STOMACH MUCOSA;

ADULT; AGED; FEMALE; GASTRIC MUCOSA; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE; STOMACH NEOPLASMS;

EID: 0031418676     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.9.1841     Document Type: Article

References (11)

1. Moncada, S., Palmer, M.J. and Higgs, E.A. (1991) Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev., 43, 109-139.
2. Stark, M.E. and Szurszewski, J.H. (1992) Role of nitric oxide in gastrointestinal and hepatic function and disease. Gastroenterology, 103 1928-1949.
3. Assurey, J., Canha, F.Q., Liew, F.Y. and Moncada, S. (1993) Feedback inhibition of nitric oxide synthase activity by nitric oxide. Br. J. Pharmacol., 108, 833-837.
4. Brown, J.F., Tepperman, B.L., Hanson, P.J., Whittle, B.J.R. and Moncada, S. (1992) Differential distribution of nitric oxide synthase between cell fractions isolated from the rat gastric mucosa. Biochem. Biophys. Res. Commun., 184, 680-685.
5. Desai, K.M., Sessa, W.C. and Vane, J.R. (1991) Involvement of nitric oxide in the reflux relaxation of the stomach to accommodate food or fluid. Nature, 351, 477-479.
6. Moochhala, S., Chhatwal, V.J.S., Chan, S.T.F., Ngoi, S.S., Chia, Y.W. and Abu Rauff. (1996) Nitric oxide synthase activity and expression in human colorectal cancer. Carcinogenesis, 17(5), 1171-1174.
7. Billiar, T.R. (1995) Nitric oxide - novel biology with clinical relevance. Ann. Surg., 221, 339-349.
8. Buttery, L.D.K., Springall, D.R., Andrade, S.P., Riveros-Moreno, V., Hart, I., Piper, P.J. and Polak, J.M. (1993) Induction of nitric oxide synthase in the neo-vasculature of experimental tumours in mice. J. Pathol., 171, 311-319.
9. Morris, S.M. Jr. and Billiar, R.R. (1994) New insights into the regulation of inducible nitric oxide synthesis. Am. J. Physiol., 266, E829-E839.
10. Blaser, M.J. (1992) Hypotheses on the pathogenesis and natural history of Helicobacter pylori-induced inflammation. Gastroenterology, 102, 720-727.
11. Yim, C., Bastian, N.R., Smith, J.C., Hibbs, J.B. Jr and Samlowski, W.E. (1993) Macrophage nitric oxide synthesis delays progression of ultraviolet light-induced murine skin cancers. Cancer Res., 53, 5507-5511.