Effects of recombinant human superoxide dismutase during reoxygenation with 21% or 100% oxygen after cerebral asphyxia in newborn piglets

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 14, Issue 2, 2003, Pages 96-101

  Solas A B ^a,b   Kalous, P ^a   Davis, J M ^c   Saugstad, O D ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c WINTHROP UNIVERSITY HOSPITAL   (United States)

Author keywords

Antioxidant; Cerebral hypoxemia ischemia hypercapnia; Newborn piglets; Reoxygenation reperfusion; Superoxide dismutase; Superoxide radicals

Indexed keywords

ANTIOXIDANT; BIOCHEMICAL MARKER; CARBON DIOXIDE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTAMIC ACID; HYPOXANTHINE; OXYGEN; RECOMBINANT COPPER ZINC SUPEROXIDE DISMUTASE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN HYPOXIA; BRAIN MICROCIRCULATION; CAROTID ARTERY OBSTRUCTION; COMMON CAROTID ARTERY; CONTROLLED STUDY; CORPUS STRIATUM; DRUG BLOOD LEVEL; LASER DOPPLER FLOWMETRY; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; REOXYGENATION; RESUSCITATION; SINGLE DRUG DOSE; SWINE;

EID: 0042830951     PISSN: 14767058     EISSN: None     Source Type: Journal    
DOI: 10.1080/jmf.14.2.96.101     Document Type: Article

References (22)

1. Andersen C, Hoffman D, Du C, et al. Effect of reoxygenation with 21% or 100% oxygen on free radical formation following hypoxia in the cerebral cortex of newborn piglets. Pediatr Res 1997;41:A
2. Vanhoutte PM. Endothelium-derived free radicals: for worse and for better. J Clin Invest 2001;107:23-5
3. O'Regan MH, Song D, VanderHeide SJ, et al. Free radicals and the ischemia-evoked extracellular accumulation of amino acids in rat cerebral cortex. Neurochem Res 1997;22:273-80
4. Rosenberg AA, Murdaugh E, White CW. The role of oxygen free radicals in postasphyxia cerebral hypoperfusion in newborn lambs. Pediatr Res 1989;26:215-19
5. Muir JK, Tynan M, Caldwell R, et al. Superoxide dismutase improves posttraumatic cortical blood flow in rats. J Neurotrauma 1995;12:179-88
6. Rosenfeld WN, Davis JM, Parton L, et al. Safety and pharmacokinetics of recombinant human superoxide dismutase administered intratracheally to premature neonates with respiratory distress syndrome. Pediatrics 1996;97:811-17
7. Feet BA, Yu XQ, Rootwelt T, et al. Effects of hypoxemia and reoxygenation with 21% or 100% oxygen in newborn piglets: extracellular hypoxanthine in cerebral cortex and femoral muscle (see comments). Crit Care Med 1997;25:1384-91
8. Lindroth P, Mopper K. High performance liquid chromatographic determination of subpicomole amounts of amino acids by precolumn fluorescence derivatization with o-phthaldialdehyde. Anal Chem 1979;51:1667-74
9. Solås A-B, Kutzsche S, Vinje M, et al. Cerebral hypoxemia-ischemia and reoxygenation with 21% or 100% oxygen in newborn piglets: effects on extracellular levels of excitatory amino acids and microcirculation. Pediatr Crit Care Med 2001;2:340-5
10. Bannister JV, Bannister WH, Rotilio G. Aspects of the structure, function, and applications of superoxide dismutase. CRC Crit Rev Biochem 1987;22:111-80
11. Silverman HS, Siddoway LA, Yavin Z, et al. Pharmacokinetics of recombinant human superoxide dismutase. J Cardiovasc Pharmacol 1990;16:107-11
12. Imaizumi S, Woolworth V, Kinouchi H, et al. Liposome-entrapped superoxide dismutase ameliorates infarct volume in focal cerebral ischaemia. Acta Neurochir Suppl (Wien) 1990;51:236-8
13. Wengenack TM, Curran GL, Poduslo JF. Postischemic, systemic administration of polyamine-modified superoxide dismutase reduces hippocampal CA1 neurodegeneration in rat global cerebral ischemia. Brain Res 1997;754:46-54
14. McDonald RJ, Berger EM, White CW, et al. Effect of superoxide dismutase encapsulated in liposomes or conjugated with polyethylene glycol on neutrophil bactericidal activity in vitro and bacterial clearance in vivo. Am Rev Respir Dis 1985;131:633-7
15. Francis JW, Ren J, Warren L, et al. Postischemic infusion of Cu/Zn superoxide dismutase or SOD:Tet451 reduces cerebral infarction following focal ischemia/reperfusion in rats. Exp Neurol 1997;146:435-43
16. Ting P, Wang P, Song H, et al. Neuro-pathophysio-biochemical profiles of neonatal asphyxia. Acta Neurochir Suppl (Wien) 1994;60:203-6
17. Strasser A, Stanimirovic D, Kawai N, et al. Hypoxia modulates free radical formation in brain microvascular endothelium. Acta Neurochir Suppl (Wien) 1997;70:8-11
18. Tasdemiroglu E, Chistenberry PD, Ardell JL, et al. Effect of superoxide dismutase on acute reperfusion injury of the rabbit brain. Acta Neurochir (Wien) 1993;120:180-6
19. Hashimoto Y, Itoh K, Nishida K, et al. Rapid superoxide production by endothelial cells and their injury upon reperfusion. J Surg Res 1994;57:693-7
20. Ditelberg JS, Sheldon RA, Epstein CJ, et al. Brain injury after perinatal hypoxia-ischemia is exacerbated in copper/zinc superoxide dismutase transgenic mice. Pediatr Res 1996;39:204-8
21. Ying W, Anderson CM, Chen Y, et al. Differing effects of copper, zinc superoxide dismutase overexpression on neurotoxicity elicited by nitric oxide, reactive oxygen species, and excitotoxins. J Cereb Blood Flow Metab 2000;20:359-68
22. Chen Y, Ying W, Simma V, et al. Overexpression of Cu,Zn superoxide dismutase attenuates oxidative inhibition of astrocyte glutamate uptake. J Neurochem 2000;75:939-45