Free radicals and the ischemia-evoked extracellular accumulation of amino acids in rat cerebral cortex

Neurochemical Research

Volumn 22, Issue 3, 1997, Pages 273-280

  O'Regan, M H ^b   Song, D ^a   VanderHeide, S J ^a   Phillis, J W ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF DETROIT MERCY   (United States)

Author keywords

catalase; glutamate, superoxide dismutase; hydrogen peroxide aspartate; prostaglandin synthase; Xanthine oxidase

Indexed keywords

ASPARTIC ACID; CATALASE; FREE RADICAL; GLUTAMIC ACID; GLYCINE; HYDROGEN PEROXIDE; PHOSPHOETHANOLAMINE; SUPEROXIDE DISMUTASE; XANTHINE; XANTHINE OXIDASE;

AMINO ACID SYNTHESIS; AMINO ACID TRANSPORT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; REPERFUSION INJURY;

ANIMALS; BASAL METABOLISM; CEREBRAL CORTEX; FREE RADICALS; ISCHEMIC ATTACK, TRANSIENT; MALE; NEUROTRANSMITTER AGENTS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; XANTHINE OXIDASE;

ANIMALIA;

EID: 0031055481     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022434604428     Document Type: Article

References (38)

1. Kontos, H. A. 1989. Oxygen radicals in CNS damage. Chem. Biol. Interact. 72:229-255.
2. Siesjo, B. K. 1992. Pathophysiology and treatment of focal cerebral ischemia. Part I. Pathophysiology. J. Neurosurg. 77:169-184.
3. Sen, S., and Phillis, J. W. 1993. Alpha-phenyl-tert-butyl-nitrone (PBN) attenuates hydroxyl radical production during ischemia/reperfusion injury of rat brain: an EPR study. Free Rad. Res. Comms. 19:255-265.
4. Phillis, J. W., and Sen, S. 1993. Oxypurinol attenuates hydroxyl radical production during ischemia/reperfusion injury of the rat cerebral cortex: an ESR study. Brain Res. 628:309-312.
5. Hall, E. D., Andrus, P. K., Althaus, J. S., and von Voightlander, P. F. 1993. Hydroxyl radical production and lipid peroxidation parallel selective post-ischemic vulnerability in gerbil brain. J. Neurosci. Res. 34:107-112.
6. McCord, J. M. 1985. Oxygen-derived free radicals in post-ischemic tissue injury. New Engl. J. Med. 312:159-163.
7. Granger, D. N., Hollwarth, M. E., and Parks, D. A. 1986. Ischemia-reperfusion injury: role of oxygen-derived free radicals. Acta Physiol. Scand. 126 (Suppl.) 548:47-63.
8. Liu, D., Yang, R., Yan, X., and McAdoo, D. J. 1994. Hydroxyl radicals generated in vivo kill neurons in rat spinal cord: electrophysiological, histological, and neurochemical results. J. Neurochem. 62:37-44.
9. Pellegrini-Giampietro, D., Cherici, G., Alesiani, M., Carla, V., and Moroni, F. 1990. Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage. J. Neurosci. 10:1035-1041.
10. 3H]aspartate from cerebral cortical synaptosomes. J. Neurochem. 62:1757-1763.
11. Halliwell, B. 1992. Reactive oxygen species and the central nervous system. J. Neurochem. 59:1609-1623.
12. Lin, Y., and Phillis, J. W. 1992. Deoxycoformycin and oxypurinol: Protection against focal ischemic brain injury in the rat. Brain Res. 571:272-280.
13. Kinuta, Y., Kikuchi, H., Ishikawa, M., Kimura, M., and Itokawa, Y. 1989. Lipid peroxidation in focal cerebral ischemia. J. Neurosurg. 71:421-429.
14. Hara, H., Kato, H., Araki, T., Onodera, H., and Kogure, K. 1991. Involvement of lipid peroxidation and inhibitory mechanisms on ischemic neuronal damage in gerbil hippocampus: quantitative autoradiographic studies on second messenger and neurotransmitter systems. Neuroscience 42:159-169.
15. +-ATPase. Am. J. Physiol. 252:H252-H257.
16. Viani, P., Cervato, G., Fiorilli, R., and Cestaro, B. 1991. Age-related differences in synaptosomal peroxidative damage and membrane properties. J. Neurochem. 56:253-258.
17. Rohn, T. T., Hinds, T. R., and Vincenzi, F. F. 1993. Ion transport ATPases as targets for free radical damage. Biochem. Pharmacol. 46:525-534.
18. Hitschke, K., Buhler, R., Appel, H. J., and Stark, G. 1994. Inactivation of the Na,K-ATPase by radiation-induced free radicals. Evidence for a radical-chain mechanism. FEBS Lett. 353:297-300.
19. 2+ concentrations. J. Neurochem. 66:2057-2066.
20. Choi, D. W. 1992. Excitotoxic cell death. J. Neurobiol. 23:1261-1276.
21. Siesjo, B. K., Zhao, Q., Pahlmark, K., Siesjo, P., Katsura, K., and Folbergrova, J. 1995. Glutamate, calcium, and free radicals as mediators of ischemic brain damage. Ann. Thorac. Surg. 59:1316-1320.
22. Phillis, J. W., Walter, G. A., Simpson, R. E. 1991. Brain adenosine and transmitter amino acid release from the ischemic rat cerebral cortex: Effects of adenosine deaminase inhibitor deoxycoformycin. J. Neurochem. 56:644-650.
23. Simpson, R. E., O'Regan, M. H., Perkins, L. M., Phillis, J. W. 1992. Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists. J. Neurochem. 58:1683-1690.
24. Phillis, J. W. and Walter, G. A. 1989a. Hypoxia/hypotension evoked release of glutamate and aspartate from the rat cerebral cortex. Neurosci. Lett. 106:147-151.
25. Phillis, J. W. and Walter, G. A. 1989b. Effect of a brief hypoxic/hypotensive episode on the in vivo release of cerebral cortical γ-aminobutyric acid and glycine. Brain Res. 540:121-123.
26. O'Regan, M. H., Perkins, L. M., and Phillis, J. W. 1995. Arachidonic acid and lysophosphatidylcholine modulate excitatory transmitter amino acid release from the rat cerebral cortex. Neurosci. Lett. 193:85-88.
27. Phillis, J. W. and O'Regan, M. H. 1996. Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortex. Brain Res. 730:150-164.
28. Abe, K., Kogure, K., Yamamoto, H., Imazawa, M., Miyamato, K. 1987. Mechanism of arachidonic acid liberation during ischemia in gerbil cortex. J. Neurochem. 48:503-509.
29. Phillis, J. W. 1996. Cerebroprotective action of the phospholipase inhibitor quinacrine in the ischemia/reperfused gerbil hippocampus. Life Sci. 58:97-101.
30. Kimelberg, H. K., Goderie, S. K., Higman, S., Pang, S., Waniewski, R. A. 1990. Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures. J. Neuroscience 10:1583-1591.
31. Phillis, J. W., Smith-Barbour, M., Perkins, L. M., O'Regan, M. H. 1994a. Characterization of glutamate, aspartate, and GABA release from ischemic rat cerebral cortex. Brain Res. Bull. 34:457-466.
32. Phillis, J. W., Perkins, L. M., and O'Regan, M. H. 1993. Potassium-evoked efflux of transmitter amino acids and purines from rat cerebral cortex. Brain Res. Bull. 31:547-552.
33. 2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity. Brain Res. 663:237-243.
34. Obrenovitch, T. P. and Richards, D. A. 1995. Extracellular neurotransmitter changes in cerebral ischemia. Cerebrovasc and Brain Metab. Rev. 7:1-54.
35. 2 action, in C. K. Chow (ed.) Cellular Antioxidant Defense Mechanisms, Vol. 2, CRC Press, Inc. Boca Raton, FL.
36. Lochner, A. and Villiers, M. 1989. Phosphatidylcholine biosynthesis in myocardial ischemia. J. Mol. Cell. Cardiol. 21:151-163.
37. Phillis, J. W., Smith-Barbour, M., Perkins, L. M., and O'Regan, M. H. 1994b. Indomethacin modulates ischemia-evoked release of glutamate and adenosine from the rat cerebral cortex. Brain Res. 652:353-356.
38. Ghribi, O., Callebert, J., Plotkine, M., and Boulu, R. G. 1994. L-NAME modulates glutamate accumulation induced by K+-depolarization but not by forebrain ischemia in the rat striatum. Neurosci. Lett. 174:34-38.