Classical and molecular cytogenetic analysis in head and neck squamous cell carcinomas

Genetics and Molecular Biology

Volumn 26, Issue 2, 2003, Pages 121-128

  Veiga, Luciana C S ^a   Bérgamo, Nádia A ^a   Kowalski, Luiz Paulo ^b   Rogatto, Silvia R ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b A C CAMARGO CANCER CENTER   (Brazil)

Author keywords

Chromosomal aberrations; Chromosome 17; FISH; Head and neck cancer

Indexed keywords

ADULT; AGED; ANEUPLOIDY; CENTROMERE; CHROMOSOME 10; CHROMOSOME 16; CHROMOSOME 17; CHROMOSOME 19; CHROMOSOME 22; CHROMOSOME 22Q; CHROMOSOME 5; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; CHROMOSOME G BAND; CHROMOSOME LOSS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE PROBE; GENETIC GAIN; HEAD AND NECK CARCINOMA; HUMAN; HUMAN TISSUE; MALE; METAPHASE CHROMOSOME; MONOSOMY; REVIEW; SQUAMOUS CELL CARCINOMA; STRUCTURAL CHROMOSOME ABERRATION; Y CHROMOSOME;

EID: 0042593126     PISSN: 14154757     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1415-47572003000200003     Document Type: Review

References (64)

1. Ah-See KW, Cooke TG, Pickford IR, Soutar D and Balmain A (1994) Allelo-type of squamous carcinoma of the head and neck using microsatellite. Cancer Res 54:1617-1621.
2. Ai H, Barrera JE, Meyers AD, Shroyer KR and Varella-Garcia M (2001) Chromosomal aneuploidy precedes morphological changes and supports multifocality in head and neck lesions. Laryngoscope 111:1853-1858.
3. AJCC, American Joint Committee on Cancer: Manual for Staging of Cancer (1998) 4th edition. JB Lippincott, Philadelphia.
4. Bayani J and Squire JA (2001) Advances in the detection of chromosomal aberrations using spectral kayotyping. Clin Genet 59:656-73.
5. Beder LB, Gunduz M, Ouchida M, Fukushima K, Gunduz E, Ito S, Sakai A, Nagai N, Nishizaki K and Shimizu K (2003) Genome-wide analysis on loss of heterozygosity in head and neck squamous cell carcinomas. Lab Invest 83:99-105.
6. Blons H, Cabelguenne A, Carnot F, Laccourreye O, de Waziers I, Hamelin R, Brasnu D, Beaune P and Laurent-Puig P (1999) Microsatellite analysis and response to chemotherapy in head and neck squamous cell carcinoma. Int J Cancer 84:410-415.
7. Bockmühl U, Schwendel A, Dietel M and Petersen I (1996) Distinct patterns of chromosomal alterations in high- and low-grade head and neck squamous cell carcinomas. Cancer Res 56:5325-5329.
8. Bockmühl U, Wolf G, Schmidt S, Schwendel A, Jahnke V, Dietel M and Petersen I (1998) Genomic alterations associated with malignancy in head and neck cancer. Head Neck 20:145-151.
9. Bockmühl U, Schulüns K, Küchler I, Petersen S and Petersen I (2000) Genetic imbalances with impact on survival in head and neck cancer patients. Am J Pathol 157: 369-375.
10. Bockmühl U, Schulüns K, Schimdt S, Matthias S and Petersen I (2002) Chromosomal alterations during metastasis formation of head and neck squamous cell carcinoma. Genes Chromosomes Cancer 33:29-35.
11. Brandt B, Vogt U, Schlotter CM, Jackisch C, Werkmeister R, Thomas M, von Eiff M, Bosse U, Assmann G and Zanker KS (1995) Prognostic relevance of aberrations in the erbB oncogenes from breast, ovarian, oral and lung cancers: double-differential polymerase chain reaction (ddPCR) for clinical diagnosis. Gene 159:35-42.
12. Brzoska PM, Levin NA, Fu KK, Kaplan MJ, Singer MI, Gray JW and Christman MF (1995) Frequent novel DNA copy number increase in squamous cell head and neck tumors. Cancer Res 55:3055-3059.
13. Califano J, van der Riet P, Westra W, Nawroz H, Clayman G, Piantadosi S, Corio R, Lee D, Greenberg B, Koch W and Sidransky D (1996) Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res 56:2488-2492.
14. Califano J, Westra WH, Meininger G, Corio R, Koch WM and Sidransky D (2000) Genetic progression and clonal relationship of recurrent premalignant head and neck lesions. Clin Cancer Res 6:347-352.
15. Chang Y, Lin Y, Tsai C, Shu C, Tsai M, Choo K and Liu ST (1992) Detection of mutations in p53 gene in human head and neck carcinomas by single strand conformation polymorphism analysis. Cancer Lett 67:167-174.
16. Decker J and Goldstein JC (1982) Risk factors in head and neck cancers. N Engl J Med 306:1151-1155.
17. Dracopoli NC (2000) Current Protocols in Human Genetics. John Wiley & Sons, Inc. (CD Version), New York.
18. El-Naggar AK, Lovell M, Killary A and Batsakis JG (1994) Trisomy 5 as the sole chromosomal abnormality in a primary mucoepidermoid carcinoma of the minor salivary gland. Cancer Genet Cytogenet 76:96-99.
19. Field JK (1995) The role of oncogenes and tumour-suppressor genes in the aetiology of oral, head and neck squamous cell carcinoma. J R Soc Med 88:35P-39P.
20. Foulkes WD, Brunet J-S, Kowalski LP, Narod AS and Franco EL (1995) Family history of cancer is a risk factor for squamous cell carcinoma of the head and neck in Brazil: a case-control study. Int J Cancer 63:769-773.
21. Gollin SM (2001) Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease. Head Neck 23:238-253.
22. Hainaut P, Hernandez T, Robinson A, Rodriguez-Tome P, Flores T, Hollstain M, Harris CC and Montesano R (1998) IARC database of TP53 gene mutation in human tumors and cell lines: updated compilation, revised formats and new visualization tolls. Nucleic Acid Res 26:205-213.
23. Hanahan D and Weinberg RA (2000) The hallmarks of cancer. Cell 100:57-70.
24. Hashimoto Y, Oga A, Kawauchi S, Furuya T, Shimizu N, Nakano T, Imate Y, Yamashita H and Sasaki K. (2001) Amplification of 3q26 approximately qter correlates with tumor progression in head and neck squamous cell carcinomas. Cancer Genet Cytogenet 129:52-56.
25. Hopman AHN, Ramaekers FCS and Vooijs GP (1992) Interphase cytogenetics of solid tumours. In: Polak JN and McGee JOJ (eds). In situ Hybridization: Principles and Practice. Oxford Science Press. VIII, pp 165-186.
26. Huang Q, Yu GP, McCormick SA, Mo J, Datta B, Mahimkar M, Lazarus P and Schaffer SP (2002) Genetic differences detected by comparative genomic hybridization in head and neck squamous cell carcinomas from different tumor sites: construction of oncogenetic trees for tumor progression. Genes Chromosomes Cancer 34:224-233.
27. Ibrahim SO, Lillehaug JR, Johannssen AC, Liavaag PG, Nilsen R and Vasstrand EN (1999) Expression of biomarkers (p53, transforming growth factor alpha, epidermal growth factor receptor, c-erbB-2/neu and the proliferative cell nuclear antigen) in oropharyngeal squamous cell carcinomas. Oral Oncol 35:302-313.
28. ISCN (1995) An International System for Human Cytogenetic Nomenclature, Mitelman F. (ed.), Skarger, Basel 1995.
29. Jin Y, Higashi K, Mandahk N, Heim S, Wennerberg J, Biörklund A, Dictor M and Mitelman F (1990) Frequent rearrangement of chromosomal bands 1p22 and 11q13 in squamous cell carcinoma of the head and neck. Genes Chromosomes Cancer 2:198-204.
30. Jin Y, Mertens F, Mandahl N, Heim S, Olegard C, Wennerberg J, Biörklund A and Mitelman F (1993) Chromosome abnormalities in eighty-three head and neck squamous cell carcinomas: Influence of culture conditions on karyotypic pattern. Cancer Res 53:2140-2146.
31. Jin Y, Mertens F, Jin C, Akervall J, Wennerberg J, Gorunova L, Mandahl N, Heim S and Mitelman F (1995) Nonrandom chromosome abnormalities in short-term cultured primary squamous cell carcinomas of the head and neck. Cancer Res 55:3204-3210.
32. Jin C, Jin Y-S, Wennerberg J, Akervall J, Grenthe B, Mandahl N, Heim S, Mitelman F and Mertens F. (1997) Clonal chromosome aberrations accumulate with age in upper aerodigestive tract mucosa. Mutat Res 374:63-72.
33. Jin Y, Hoglund M, Jin C, Martins C, Wennerberg J, Akervall J, Mandahl N, Mitelman F and Mertens F (1998) FISH characterization of head and neck carcinomas reveals that amplification of band 11q13 is associated with deletion of distal 11q. Genes Chromosomes Cancer 22:312-320.
34. Jin C, Jin Y-S, Wennerberg J, Akervall J, Dictor M and Mertens F (2002) Karyotypic heterogeneity and clonal evolution in squamous cell carcinomas of the head and neck. Cancer Genet Cytogenet 132:85-96.
35. Komiyama T, Matsumura K and Tsuchida N (1997) Comparison of DNA copy numbers in original oral squamous cell carcinomas and corresponding cell lines by comparative genomic hybridization. Jpn J Cancer Res 88:476-483.
36. Kropveld A, Rozemuller E, Leppers F, Scheidel K, de Weger R, Koole R, Hordijk GJ, Slootweg PJ and Tilanus MG (1999) Sequencing analysis of RNA and DNA of exons 1 through 11 shows p53 gene alterations to be present in almost 100% of head and neck squamous cell cancers. Lab Invest 79:347-353.
37. Martins C, Jin Y, Jin C, Wennerberg J, Höglund M and Mertens F (1999) Fluorescent in situ hybridization (FISH) characterization of pericentromeric breakpoints on chromosome 5 in head and neck squamous cell carcinomas. Eur J Cancer 35:498-501.
38. Mertens F, Johansson B, Hoglund M and Mittelman F (1997) Chromosomal imbalance maps of malignant solid tumors: a cytogenetic survey of 3185 neoplasms. Cancer Res 57:2765-2780.
39. Mitelman F, Johansson B and Mertens F (2003) Mitelman Database of Chromosome Aberration in Cancer. Mitelman F, Johansson B, Mertens F (eds). http://cgap.nci.nih.gov/Chromosomes/Mitelman.
40. Nagai MA, Miracca EC, Yamamoto L, Moura RP, Simpson AJ, Kowalski LP and Brentani RR. (1998) TP53 genetic alterations in head and neck carcinomas from Brazil. Int. J. Cancer 76:13-18.
41. Nawroz H, van der Riet P, Hruban RH, Koch W, Ruppert JM and Sidransky D (1994) Allelotype of head and neck squamous cell carcinoma. Cancer Res 54:1152-1155.
42. Nowell PC (1976) The clonal evolution of tumor cell populations. Science 194:23-28.
43. Oh Y and Mao L (1997) Biomarkers in head and neck carcinoma. Curr Opin Oncol 9:247-256.
44. Owens W, Field JK, Howard PJ and Stell PM (1992) Multiple cytogenetic aberrations in squamous cell carcinomas of the head and neck. Oral Oncol Eur J Cancer 28B: 17-21.
45. Ransom DT, Barnett TC, Bot J, de Boer B, Metcalf C, Davidson JA and Turbett GR (1998) Loss of heterozygosity on chromosome 2q: possibly a poor prognostic factor in head and neck cancer. Head Neck 20:404-410.
46. Rao PH, Sreekantalah C, Schantz SP and Chaganti RSK (1994) Cytogenetic analysis of 11 squamous cell carcinomas of the head and neck. Cancer Genet Cytogenet 77:60-64.
47. Redon R, Muller D, Caulee K, Wanherdrick K, Abecassis J and du Manoir S (2001) A simple specific pattern of chromosomal aberrations at early stages of head and neck squamous cell carcinomas: PIK3CA but not p63 gene as a likely target of 3q26-qter gains. Cancer Res 61:4122-4129.
48. Reid BC, Winn DM, Morse DE and Pendrys DG (2000) Head and neck in situ carcinoma: incidence, trends and survival. Oral Oncol 36:414-420.
49. Rogatto SR, Casartelli C, Rainho CA and Barbieri-Neto J (1993) Chromosomes in the genesis and progression of ependymomas. Cancer Genet Cytogenet 69:146-152.
50. Rogatto SR, Rainho CA, Zhang ZM, Figueiredo F, Barbieri-Neto J, Georgetto SM and Squire JA (1999) Hemangioendothelioma of bone in a patient with a constitutional supernumerary marker. Cancer Genet Cytogenet 110:23-27.
51. Scheres Vac MJC (1972) Identification of two Robertsonian translocations with a Giemsa banding technique. Hum Genet 15:253-256.
52. Scully C and Field JK (1997) Genetic aberrations in squamous cell carcinoma of the head and neck (SCCHN), with reference to oral carcinoma (Review). Int J Oncol 10:5-21.
53. Scully C, Field JK and Tanzawa H (2000) Genetic aberrations in oral or head and neck squamous cell carcinoma 2: chromosomal aberrations. Oral Oncol 36:311-327.
54. Shin DM, Lee JS, Lippman SM, Lee JJ, Tu ZN, Choi G, Heyne K, Shin HJ, Ro JY, Goepfert H, Hong WK and Hittelman WN. (1996) p53 expressions: predicting recurrence and second primary tumours in head and neck squamous cell carcinoma. J Natl Cancer Inst 88:519-529.
55. Soder AI, Hopman AHN, Ramaekers FCS, Conradt C and Bosch FX (1995) Distinct nonradom patterns of chromosomal aberrations in the progression of squamous cell carcinomas of the head and neck. Cancer Res 55:5030-5037.
56. Speicher MR, Howe C, Crotty P, du Manoir S, Costa J and Ward DC (1995) Comparative genomic hybridization detects novel deletions and amplifications in head and neck squamous cell carcinomas. Cancer Res 55:1010-1013.
57. Squire JA, Bayani J, Luk C, Unwin L, Tokunaga J, MacMillan C, Irish J, Brown D, Gullane P and Kamel-Reid S (2002) Molecular cytogenetic analysis of head and neck squamous cell carcinoma: by comparative genomic hybridization, spectral karyotyping, and expression array analysis. Head Neck 24:874-887.
58. van Dyke DL, Worsham MJ, Benninger MS, Krause CJ, Baker SR, Wolf GT, Drumheller T, Tilley BC and Carey TE. (1994) Recurrent cytogenetic abnormalities in squamous cell carcinomas of the head and neck region. Genes Chromosomes Cancer 9:192-206.
59. Varella-Garcia M, Gemmill RM, Rabenhorst SH, Lotto A, Drabkin HA, Archer PA and Franklin WA. (1998) Chromosomal duplication accompanies allelic loss in non-small cell lung carcinoma. Cancer Res 58:4701-4707.
60. Werkmeister R, Brandt B and Joos U (1996) The erbB oncogene as prognostic markers in oral squamous cell carcinomas. Am J Surg 172:681-683.
61. Werkmeister R, Brandt B and Joos U (2000) Clinical relevance of erbB-1 and -2 oncogenes in oral carcinomas. Oral Oncol 36:100-105.
62. Wolff E, Girod S, Liehr T, Vorderwulbecke U, Ries J, Steininger H and Gebhart E. (1998) Oral squamous cell carcinomas are characterized by a rather uniform pattern of genomic imbalances detected by comparative genomic hybridization. Oral Oncol 34:186-190.
63. World Health Organization (1990) International Classification of Diseases for Oncology, 2nd edition. World Health Organization, Geneva.
64. Xia W, Lau YK, Zhang HZ, Xiao FY, Johnston DA, Liu AR, Li L, Katz RL and Hung MC (1999) Combination of EGFR, Her-2/neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members. Clin Cancer Res 5:4164-4174.