Design and synthesis of S-(-)-2-[[4-(napht-1-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2- a]pyrazine (CSP-2503) using computational simulation. A 5-HT1A receptor agonist

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 8, 2003, Pages 1429-1432

  López Rodríguez, María L ^a   Morcillo, Ma José ^b   Fernández, Esther ^a   Benhamú, Bellinda ^a   Tejada, Ignacio ^a   Ayala, David ^a   Viso, Alma ^a   Olivella, Mireia ^c   Pardo, Leonardo ^c   Delgado, Mercedes ^a   Manzanares, Jorge ^a   Fuentes, José A ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD NACIONAL DE EDUCACIÓN A DISTANCIA   (Spain)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[4 (NAPHTH 1 YL)PIPERAZIN 1 YL]METHYL] 1,4 DIOXOPERHYDROPYRROLO[1,2 ALPHA]PYRAZINE; ALPHA 1 ADRENERGIC RECEPTOR; ANXIOLYTIC AGENT; CSP 2503; PIPERAZINE DERIVATIVE; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; RECEPTOR AFFINITY; SIMULATION; SYNAPSE; TRANQUILIZING ACTIVITY;

EID: 0042452222     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00160-4     Document Type: Article

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