The chemotactic and mitogenic responses of vascular smooth muscle cells to insulin-like growth factor-I require the activation of ERK1/2

Molecular and Cellular Endocrinology

Volumn 206, Issue 1-2, 2003, Pages 75-83

  Duan, Cunming ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Insulin like growth factor I; Migration; Mitogen activated protein kinase; Proliferation; Vascular smooth muscle cell

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTISENSE OLIGONUCLEOTIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHOTRANSFERASE; PLATELET DERIVED GROWTH FACTOR; SOMATOMEDIN C;

ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; MITOGENESIS; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 0042433330     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(03)00212-0     Document Type: Article

References (30)

1. Bai H.Z., Pollman M.J., Inishi Y., Gibbons G.H. Regulation of vascular smooth muscle cell apoptosis - modulation of bad by a phosphatidylinositol 3-kinase-dependent pathway. Circ. Res. 85:1999;229-237.
2. Bayes-Genis A., Conover C.A., Schwartz R.S. The insulin-like growth factor axis - a review of atherosclerosis and restenosis. Circ. Res. 86:2000;125-130.
3. Berrou E., Bryckaert M. Platelet-derived growth factor inhibits smooth muscle cell adhesion to fibronectin by ERK-dependent and ERK-independent pathways. J. Biol. Chem. 276:2001;39303-39309.
4. Bornfeldt K.E., Raines E.W., Nakano T., Graves L.M., Krebs E.G., Ross R. Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation. J. Clin. Invest. 93:1994;1266-1274.
5. Bornfeldt K.E., Raines E.W., Graves L.M., Skinner M.P., Krebs E.G., Ross R. Platelet-derived growth factor: distinct signal transduction pathways associated with migration versus proliferation. Ann. N. Y. Acad. Sci. 766:1995;416-430.
6. Clemmons D.R. Growth factors and atherosclerosis. Diabetes Rev. 5:1997;353-364.
7. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 362:1993;801-809.
8. Delafontaine P., Meng X.P., Ku L., Du J. Regulation of vascular smooth muscle cell insulin-like growth factor I receptor by phosphorothioate oligonucleotides. J. Biol. Chem. 270:1995;14383-14388.
9. Du J., Delafontaine P. Inhibition of vascular smooth muscle cell growth through antisense transcription of a rat insulin-like growth factor I receptor cDNA. Circ. Res. 76:1995;963-972.
10. Duan C. Specifying the cellular responses to insulin-like growth factor (IGF) signals: Role of IGF binding proteins. J. Endocrinol. 175:2002;41-54.
11. Duan C., Hawes S.B., Prevette T., Clemmons D.R. Insulin-like growth factor (IGF) -I regulates IGF binding protein-5 synthesis through transcriptional activation of the gene in aortic smooth muscle cells. J. Biol. Chem. 271:1996;4280-4288.
12. Duan C., Limatta M.B., Bottum O.L. Insulin-like growth factor (IGF)-I regulates IGF binding protein-5 expression through the phosphatidylinositol-3-kinase, PKB/Akt and p70 S6 kinase signaling pathway. J. Biol. Chem. 274:1999;37147-37153.
13. Duan C., Bauchat J.R., Hsieh T. Phosphatidylinositol 3-kinase is required for IGF-I-induced vascular smooth muscle cell proliferation and migration. Circ. Res. 86:2000;15-23.
14. Favata M.F., Horiuchi K.Y., Manos E.J., Daulerio A.J., Stradley D.A., Feeser W.S., Van Dyk D.E., Pitts W.J., Earl R.A., Hobbs F., Copeland R.A., Magolda R.L., Scherle P.A., Trzaskos J.M. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273:1998;18623-18632.
15. Folli F., Kahn C.R., Hansen H., Bouchie J.L., Feenet E.P. Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. J. Clin. Invest. 100:1997;2158-2169.
16. Graf K., Xi X.P., Yang D., Fleck E., Hsueh W.A., Law R.E. Mitogen-activated protein kinase activation is involved in platelet-derived growth factor-directed migration by vascular smooth muscle cells. Hypertension. 29:1997;334-339.
17. Graves L.M., Bornfeldt K.E., Sidhu J.S., Argast G.M., Raines F.W., Ross R., Leslie C.C., Krebs E.G. Platelet-derived growth factor stimulates protein kinase A through a mitogen-activated protein kinase-dependent pathway in human arterial smooth muscle cells. J. Biol. Chem. 272:1996;505-511.
18. Imai Y., Clemmons D.R. Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascular smooth muscle cell migration and deoxyriboncleic acid synthesis by insulin-like growth factor-I. Endocrinology. 140:1999;4228-4235.
19. Kim B., Leventhal P.S., Saltiel A.R., Feldman E.L. Insulin-like growth factor-I-mediated neurite outgrowth in vitro requires mitogen-activated protein kinase activation. J. Biol. Chem. 272:1997;21268-21273.
20. Koyama H., Nishizawa Y., Hosoi M., Kogawa K., Shioi A., Morii H. The fumagillin analogue TNP-470 inhibits DNA synthesis of vascular smooth muscle cells stimulated by platelet-derived growth factor and insulin-like growth factor-I-Possible involvement of cyclin-dependent kinase 2. Circ. Res. 79:1996;757-764.
21. LeRoith D., Werner H., Beitner-Johnson D., Roberts C.T.J.r. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr. Rev. 16:1995;143-163.
22. Martiny-Baron G., Kazanietz M.G., Mischak H., Blumberg P.M., Kochs G., Hug H., Marme D., Schachtele C. Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976. J. Biol. Chem. 268:1993;9194-9197.
23. Parrizas M., Saltiel A.R., LeRoith D. Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways. J. Biol. Chem. 272:1997;154-161.
24. Pavlovic-Surjancev B., Cahill B.L., Perlman R.L. Staurosporine activates a 60,000 Mr protein-kinase in bovine chromaffin cells that phosphorylates myelin basic protein in vitro. J. Neurochem. 59:1992;2134-2140.
25. Takagi Y., Kashiwagi A., Tanaka Y., Maegawa H., Shigeta Y. Insulin-specific activation of S6 kinase and IRS desensitization in cultured rat vascular smooth muscle cells. Atherosclerosis. 113:1995;19-27.
26. Thommes K.B., Hoppe J., Vetter H., Sachinidis A. The synergistic effect of PDGF-AA and IGF-I on SMC proliferation might be explained by the differential activation of their intracellular signaling pathways. Exp. Cell Res. 226:1996;59-66.
27. Toullec D., Pianetti P., Coste H., Bellevergue P., Grand-Perret T., Ajakane M., Baudet V., Boissin P., Boursier E., Loriolle F., Duhamel L., Charon D., Kirilovsky J. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266:1991;15771-15781.
28. White M.F. The IRS-signaling system: a network of docking proteins that mediate insulin action. Mol. Cell. Biochem. 182:1998;3-11.
29. Yano K., Bauchat J.R., Liimatta M., Clemmons D.R., Duan C. Down-regulation of protein kinase C inhibits IGF-I-induced vascular smooth muscle cell proliferation, migration and gene expression. Endocrinology. 140:1999;4622-4632.
30. Zaina S., Pettersson L., Ahrén B., Brånén L., Hassan A.B., Lindhol M., Mattsson R., Thyberg J., Nilsson J. Insulin-like growth factor II plays a central role in atherosclerosis in a mouse model. J. Biol. Chem. 277:2002;4505-4511.