메뉴 건너뛰기




Volumn 182, Issue 1, 2000, Pages 180-190

Enterotoxin adjuvants have direct effects on T cells and antigen- presenting cells that result in either interleukin-4-dependent or - independent immune responses

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; IMMUNOGLOBULIN A; INTERLEUKIN 4; INTERLEUKIN 5;

EID: 0033929615     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315694     Document Type: Article
Times cited : (53)

References (47)
  • 1
    • 0023938398 scopus 로고
    • Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens
    • 1. Clements JD, Hartzog NM, Lyon FL. Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens. Vaccine 1988; 6:269-77.
    • (1988) Vaccine , vol.6 , pp. 269-277
    • Clements, J.D.1    Hartzog, N.M.2    Lyon, F.L.3
  • 2
    • 0027486404 scopus 로고
    • Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems
    • 2. Holmgren J, Lycke N, Czerkinsky C. Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems. Vaccine 1993; 11: 1179-84.
    • (1993) Vaccine , vol.11 , pp. 1179-1184
    • Holmgren, J.1    Lycke, N.2    Czerkinsky, C.3
  • 3
    • 0007205169 scopus 로고    scopus 로고
    • A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity
    • 3. Yamamoto S, Kiyono H, Yamamoto M, et al. A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity. Proc Natl Acad Sci USA 1997; 94:5267-72.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 5267-5272
    • Yamamoto, S.1    Kiyono, H.2    Yamamoto, M.3
  • 4
    • 0028807596 scopus 로고
    • Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4
    • 4. Marinaro M, Staats HF, Hiroi T, et al. Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4. J Immunol 1995; 155:4621-9.
    • (1995) J Immunol , vol.155 , pp. 4621-4629
    • Marinaro, M.1    Staats, H.F.2    Hiroi, T.3
  • 5
    • 0027183310 scopus 로고
    • Helper T cell subsets for immunoglobulin A responses: Oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues
    • 5. Xu-Amano J, Kiyono H, Jackson RJ, et al. Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. J Exp Med 1993; 178:1309-20.
    • (1993) J Exp Med , vol.178 , pp. 1309-1320
    • Xu-Amano, J.1    Kiyono, H.2    Jackson, R.J.3
  • 6
    • 0025338731 scopus 로고
    • Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: Role of cAMP in T cell proliferation
    • 6. Munoz E, Zubiaga AM, Merrow M, Sauter NP, Huber BT. Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: role of cAMP in T cell proliferation. J Exp Med 1990; 172: 95-103.
    • (1990) J Exp Med , vol.172 , pp. 95-103
    • Munoz, E.1    Zubiaga, A.M.2    Merrow, M.3    Sauter, N.P.4    Huber, B.T.5
  • 7
    • 19144364760 scopus 로고    scopus 로고
    • Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin
    • 7. Takahashi I, Kiyono H, Marinaro M, et al. Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin. J Infect Dis 1996; 173:627-35.
    • (1996) J Infect Dis , vol.173 , pp. 627-635
    • Takahashi, I.1    Kiyono, H.2    Marinaro, M.3
  • 8
    • 0025082313 scopus 로고
    • Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
    • 8. LeGros G, Ben-Sasson SZ, Seder R, Finkelman FD, Paul WE. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J Exp Med 1990; 172:921-9.
    • (1990) J Exp Med , vol.172 , pp. 921-929
    • LeGros, G.1    Ben-Sasson, S.Z.2    Seder, R.3    Finkelman, F.D.4    Paul, W.E.5
  • 9
    • 0027959893 scopus 로고
    • Single IL-2-secreting precursor CD4 T cell can develop into Th1 or Th2 cytokine secretion phenotype
    • 9. Sad S, Mosmann TR. Single IL-2-secreting precursor CD4 T cell can develop into Th1 or Th2 cytokine secretion phenotype. J Immunol 1994; 153: 3514-22.
    • (1994) J Immunol , vol.153 , pp. 3514-3522
    • Sad, S.1    Mosmann, T.R.2
  • 10
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • 10. Swain SL, Weinberg AD, English M, Huston G. IL-4 directs the development of Th2-like helper effectors. J Immunol 1990; 145:3796-806.
    • (1990) J Immunol , vol.145 , pp. 3796-3806
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 12
    • 0029874545 scopus 로고    scopus 로고
    • + Th2 cells producing IL-6 and IL-10 are associated with mucosal IgA responses
    • + Th2 cells producing IL-6 and IL-10 are associated with mucosal IgA responses. Infect Immun 1996; 64:1516-25.
    • (1996) Infect Immun , vol.64 , pp. 1516-1525
    • Okahashi, N.1    Yamamoto, M.2    VanCott, J.L.3
  • 13
    • 0028906467 scopus 로고
    • Impaired mucosal immune responses in interleukin-4-targeted mice
    • 13. Vajdy M, Kosco-Vilbois MH, Kopf M, Kohler G, Lyke N. Impaired mucosal immune responses in interleukin-4-targeted mice. J Exp Med 1995; 181: 41-53.
    • (1995) J Exp Med , vol.181 , pp. 41-53
    • Vajdy, M.1    Kosco-Vilbois, M.H.2    Kopf, M.3    Kohler, G.4    Lyke, N.5
  • 14
    • 0023748643 scopus 로고
    • Recombinant murine IL-5 induces high rate IgA synthesis in cycling IgA-positive Peyer's patch B cells
    • 14. Beagley KW, Eldridge JH, Kiyono H, et al. Recombinant murine IL-5 induces high rate IgA synthesis in cycling IgA-positive Peyer's patch B cells. J Immunol 1988; 141:2035-42.
    • (1988) J Immunol , vol.141 , pp. 2035-2042
    • Beagley, K.W.1    Eldridge, J.H.2    Kiyono, H.3
  • 15
    • 0024362523 scopus 로고
    • Interleukins and IgA synthesis. Human and murine IL-6 induce high rate IgA secretion in IgA-committed B cells
    • 15. Beagley K, Eldridge JH, Lee F, et al. Interleukins and IgA synthesis. Human and murine IL-6 induce high rate IgA secretion in IgA-committed B cells. J Exp Med 1989; 169:2133-48.
    • (1989) J Exp Med , vol.169 , pp. 2133-2148
    • Beagley, K.1    Eldridge, J.H.2    Lee, F.3
  • 16
    • 0028234789 scopus 로고
    • Interleukin 10 induces B lymphocytes from IgA-deficient patients to secrete IgA
    • 16. Briere F, Bridon JM, Chevet D, et al. Interleukin 10 induces B lymphocytes from IgA-deficient patients to secrete IgA. J Clin Invest 1994; 94:97-104.
    • (1994) J Clin Invest , vol.94 , pp. 97-104
    • Briere, F.1    Bridon, J.M.2    Chevet, D.3
  • 17
    • 0023606511 scopus 로고
    • A mouse T cell product that preferentially enhances IgA production. I. Biologic characterization
    • 17. Coffman RL, Shrader B, Carty J, Mosmann TR, Bond MW. A mouse T cell product that preferentially enhances IgA production. I. Biologic characterization. J Immunol 1987; 139:3685-90.
    • (1987) J Immunol , vol.139 , pp. 3685-3690
    • Coffman, R.L.1    Shrader, B.2    Carty, J.3    Mosmann, T.R.4    Bond, M.W.5
  • 18
    • 0024357742 scopus 로고
    • IL-6 is a potent co-factor of IL-1 in IgM synthesis and of IL-5 in IgA synthesis
    • 18. Kunimoto DY, Nordan RP, Strober W. IL-6 is a potent co-factor of IL-1 in IgM synthesis and of IL-5 in IgA synthesis. J Immunol 1989; 143:2230-5.
    • (1989) J Immunol , vol.143 , pp. 2230-2235
    • Kunimoto, D.Y.1    Nordan, R.P.2    Strober, W.3
  • 19
    • 0343978503 scopus 로고    scopus 로고
    • Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella
    • 19. VanCott JL, Staats HF, Pascual DW, et al. Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. J Immunol 1996; 156:1504-14.
    • (1996) J Immunol , vol.156 , pp. 1504-1514
    • VanCott, J.L.1    Staats, H.F.2    Pascual, D.W.3
  • 21
    • 0031569528 scopus 로고    scopus 로고
    • Genetically engineered nontoxic vaccine adjuvant that combine B cell targeting with immunomodulation by cholera toxin A1 subunit
    • 21. Ågren LC, Ekman L, Lowenadler B, Lycke NY. Genetically engineered nontoxic vaccine adjuvant that combine B cell targeting with immunomodulation by cholera toxin A1 subunit. J Immunol 1997; 158:3936-46.
    • (1997) J Immunol , vol.158 , pp. 3936-3946
    • Ågren, L.C.1    Ekman, L.2    Lowenadler, B.3    Lycke, N.Y.4
  • 22
    • 0031296660 scopus 로고    scopus 로고
    • The mucosal adjuvanticity of cholera toxin involves enhancement of costimulatory activity by selective up-regulation of B7.2 expression
    • 22. Cong Y, Weaver CT, Elson CO. The mucosal adjuvanticity of cholera toxin involves enhancement of costimulatory activity by selective up-regulation of B7.2 expression. J Immunol 1997; 159:5301-8.
    • (1997) J Immunol , vol.159 , pp. 5301-5308
    • Cong, Y.1    Weaver, C.T.2    Elson, C.O.3
  • 23
    • 0033564665 scopus 로고    scopus 로고
    • Direct effects on antigen-presenting cells and T lymphocytes explain the adjuvanticity of a nontoxic cholera toxin mutant
    • 23. Yamamoto M, Kiyono H, Yamamoto S, et al. Direct effects on antigen-presenting cells and T lymphocytes explain the adjuvanticity of a nontoxic cholera toxin mutant. J Immunol 1999; 162:7015-21.
    • (1999) J Immunol , vol.162 , pp. 7015-7021
    • Yamamoto, M.1    Kiyono, H.2    Yamamoto, S.3
  • 24
    • 0028296259 scopus 로고
    • Simple method of purification of Escherichia coli heat-labile enterotoxin and cholera toxin using immobilized galactose
    • 24. Uesaka Y, Otsuka Y, Lin Z, et al. Simple method of purification of Escherichia coli heat-labile enterotoxin and cholera toxin using immobilized galactose. Microb Pathog 1994; 16:71-6.
    • (1994) Microb Pathog , vol.16 , pp. 71-76
    • Uesaka, Y.1    Otsuka, Y.2    Lin, Z.3
  • 25
    • 0027453689 scopus 로고
    • Optimizing oral vaccines: Induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant
    • 25. Jackson RJ, Fujihashi K, Xu-Amano J, Kiyono H, McGhee JR. Optimizing oral vaccines: induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant. Infect Immun 1993; 61:4272-9.
    • (1993) Infect Immun , vol.61 , pp. 4272-4279
    • Jackson, R.J.1    Fujihashi, K.2    Xu-Amano, J.3    Kiyono, H.4    McGhee, J.R.5
  • 26
    • 0025737943 scopus 로고
    • In vitro measurement of antigen-specific cell-mediated immune responses using recombinant HIV-1 proteins absorbed to latex microspheres
    • 26. Wu JY, Riggin CH, Seals JR, Murphy CI, Newman MJ. In vitro measurement of antigen-specific cell-mediated immune responses using recombinant HIV-1 proteins absorbed to latex microspheres. J Immunol Methods 1991; 143:1-9.
    • (1991) J Immunol Methods , vol.143 , pp. 1-9
    • Wu, J.Y.1    Riggin, C.H.2    Seals, J.R.3    Murphy, C.I.4    Newman, M.J.5
  • 27
    • 0028877001 scopus 로고
    • Polarized Th2 cytokine expression by both mucosal γδ and αβ T cells
    • 27. Hiroi T, Fujihashi K, McGhee JR, Kiyono H. Polarized Th2 cytokine expression by both mucosal γδ and αβ T cells. Eur J Immunol 1995; 25: 2743-51.
    • (1995) Eur J Immunol , vol.25 , pp. 2743-2751
    • Hiroi, T.1    Fujihashi, K.2    McGhee, J.R.3    Kiyono, H.4
  • 28
    • 0028327705 scopus 로고
    • Multi-target PCR analysis by capillary electrophoresis and laser-induced fluorescence
    • 28. Lu W, Han DS, Yuan J, Andrieu JM. Multi-target PCR analysis by capillary electrophoresis and laser-induced fluorescence. Nature 1994; 368:269-71.
    • (1994) Nature , vol.368 , pp. 269-271
    • Lu, W.1    Han, D.S.2    Yuan, J.3    Andrieu, J.M.4
  • 29
    • 0030030884 scopus 로고    scopus 로고
    • Absence of exogenous IL-4-induced apoptosis of gingival macrophage may contribute to chronic inflammation in periodontal diseases
    • 29. Yamamoto M, Kawabata K, Fujihashi K, et al. Absence of exogenous IL-4-induced apoptosis of gingival macrophage may contribute to chronic inflammation in periodontal diseases. Am J Pathol 1996; 148:331-9.
    • (1996) Am J Pathol , vol.148 , pp. 331-339
    • Yamamoto, M.1    Kawabata, K.2    Fujihashi, K.3
  • 30
    • 0024537991 scopus 로고
    • Measurement of antigen-specific mouse IgE by a fluorometric reverse (IgE-capture) ELISA
    • 30. Sakaguchi M, Inouye S, Miyazawa H, Tamura S. Measurement of antigen-specific mouse IgE by a fluorometric reverse (IgE-capture) ELISA. J Immunol Methods 1989; 116:181-7.
    • (1989) J Immunol Methods , vol.116 , pp. 181-187
    • Sakaguchi, M.1    Inouye, S.2    Miyazawa, H.3    Tamura, S.4
  • 31
    • 0029986760 scopus 로고    scopus 로고
    • Luminometry: A novel bioluminescent immunoassay enhances the quantitation of mucosal and systemic antibody responses
    • 31. Jackson RJ, Fujihashi K, Kiyono H, McGhee JR. Luminometry: a novel bioluminescent immunoassay enhances the quantitation of mucosal and systemic antibody responses. J Immunol Methods 1996; 190:189-97.
    • (1996) J Immunol Methods , vol.190 , pp. 189-197
    • Jackson, R.J.1    Fujihashi, K.2    Kiyono, H.3    McGhee, J.R.4
  • 33
    • 0022493589 scopus 로고
    • Characterization of the receptor for cholera toxin and Escherichia coli heat-labile enterotoxin in rabbit brush borders
    • 33. Griffiths SL, Finkelstein RA, Critchley RR. Characterization of the receptor for cholera toxin and Escherichia coli heat-labile enterotoxin in rabbit brush borders. Biochem J 1986; 238:313-22.
    • (1986) Biochem J , vol.238 , pp. 313-322
    • Griffiths, S.L.1    Finkelstein, R.A.2    Critchley, R.R.3
  • 34
    • 0019935016 scopus 로고
    • Rabbit intestinal glycoprotein receptor for Escherichia coli heat-labile enterotoxin lacking affinity for cholera toxin
    • 34. Holmgren J, Fredman P, Lindblad M, Svennerholm AM, Svennerholm L. Rabbit intestinal glycoprotein receptor for Escherichia coli heat-labile enterotoxin lacking affinity for cholera toxin. Infect Immun 1982; 38:424-33.
    • (1982) Infect Immun , vol.38 , pp. 424-433
    • Holmgren, J.1    Fredman, P.2    Lindblad, M.3    Svennerholm, A.M.4    Svennerholm, L.5
  • 35
    • 0021830077 scopus 로고
    • Comparison of receptors for cholera and Escherichia coli enterotoxins in human intestine
    • 35. Holmgren J, Lindblad M, Fredman P, Svennerholm L, Myrvold H. Comparison of receptors for cholera and Escherichia coli enterotoxins in human intestine. Gastroenterology 1985; 89:27-35.
    • (1985) Gastroenterology , vol.89 , pp. 27-35
    • Holmgren, J.1    Lindblad, M.2    Fredman, P.3    Svennerholm, L.4    Myrvold, H.5
  • 36
    • 0028135424 scopus 로고
    • Humoral immune responses in CD40 ligand deficient mice
    • 36. Renshaw BR, Fanslow WCI, Armitage RJ, et al. Humoral immune responses in CD40 ligand deficient mice. J Exp Med 1994; 180:1889-900.
    • (1994) J Exp Med , vol.180 , pp. 1889-1900
    • Renshaw, B.R.1    Fanslow, W.C.I.2    Armitage, R.J.3
  • 37
    • 0028486131 scopus 로고
    • Mice deficient for the CD40 ligand
    • 37. Xu J, Foy TM, Laman JD, et al. Mice deficient for the CD40 ligand. Immunity 1994; 1:423-31.
    • (1994) Immunity , vol.1 , pp. 423-431
    • Xu, J.1    Foy, T.M.2    Laman, J.D.3
  • 38
    • 0026458260 scopus 로고
    • Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin
    • 38. Spangler BD. Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol Rev 1992; 56:622-47.
    • (1992) Microbiol Rev , vol.56 , pp. 622-647
    • Spangler, B.D.1
  • 40
    • 0028819315 scopus 로고
    • CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL
    • 40. Lanier LL, O'Fallon S, Somoza C, et al. CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. J Immunol 1995; 154:97-105.
    • (1995) J Immunol , vol.154 , pp. 97-105
    • Lanier, L.L.1    O'Fallon, S.2    Somoza, C.3
  • 41
    • 0030584924 scopus 로고    scopus 로고
    • Costimulation of IL-4 production by murine B7-1 and B7-2 molecules
    • 41. Natesan M, Razi-Wolf Z, Reiser H. Costimulation of IL-4 production by murine B7-1 and B7-2 molecules. J Immunol 1996; 156:2783-91.
    • (1996) J Immunol , vol.156 , pp. 2783-2791
    • Natesan, M.1    Razi-Wolf, Z.2    Reiser, H.3
  • 42
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
    • 42. Kuchroo VK, Das MP, Brown JA. et al. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 1995; 80:707-18.
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1    Das, M.P.2    Brown, J.A.3
  • 43
    • 0029073050 scopus 로고
    • B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4
    • 43. Freeman GJ, Boussiotis VA, Anumanthan A, et al. B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4. Immunity 1995; 2:523-32.
    • (1995) Immunity , vol.2 , pp. 523-532
    • Freeman, G.J.1    Boussiotis, V.A.2    Anumanthan, A.3
  • 44
    • 0028900297 scopus 로고
    • Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse
    • 44. Lenschow DJ, Ho SC, Sattar H, et al. Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. J Exp Med 1995; 181:1145-55.
    • (1995) J Exp Med , vol.181 , pp. 1145-1155
    • Lenschow, D.J.1    Ho, S.C.2    Sattar, H.3
  • 47
    • 0027512506 scopus 로고
    • Cytokine synthesis by intestinal intraepithelial lymphocytes. Both γ/δ T cell receptor positive and α/β T cell receptor-positive T cells in the G1 phase of cell cycle produce IFN-γ and IL-5
    • 47. Yamamoto M, Fujihashi K, Beagley KW, McGhee JR, Kiyono H. Cytokine synthesis by intestinal intraepithelial lymphocytes. Both γ/δ T cell receptor positive and α/β T cell receptor-positive T cells in the G1 phase of cell cycle produce IFN-γ and IL-5. J Immunol 1993; 150:106-14.
    • (1993) J Immunol , vol.150 , pp. 106-114
    • Yamamoto, M.1    Fujihashi, K.2    Beagley, K.W.3    McGhee, J.R.4    Kiyono, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.