Identification of a peptide inducing experimental autoimmune uveoretinitis (EAU) in H-2A(k)-carrying mice

Clinical and Experimental Immunology

Volumn 111, Issue 2, 1998, Pages 442-449

  Namba, K ^a,b   Ogasawara, K ^a   Kitaichi, N ^a,b   Matsuki, N ^a   Takahashi, A ^a   Sasamoto, Y ^b   Kotake, S ^b   Matsuda, H ^b   Iwabuchi, K ^a   Ohno, S ^c   Onoe K ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

EAU; IRBP; MHC restriction; Peptide antigen

Indexed keywords

PEPTIDE; RETINOID BINDING PROTEIN; T LYMPHOCYTE RECEPTOR;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; FEMALE; HAPLOTYPE; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; T LYMPHOCYTE; UVEORETINITIS;

EID: 6844226208     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00514.x     Document Type: Article

References (25)

1. Wacker WB, Donoso LA, Kalsow CM et al. Experimental allergic uveitis. Isolation, characterization and localization of a soluble uveitopathogenic antigen from bovine retina. J Immunol 1977; 119:1949-58.
2. Gery I, Mochizuki M, Nussenblatt RB. Retinal specific antigens and immunopathogenic processes they provoke. Prog Retinal Res 1986; 5:75-109.
3. Caspi RR. Basic mechanisms in immune-mediated uveitic disease. In: Lightman SL, ed. Immunology of eye disease. Lancaster, UK: Kluwer Academic Publishers, 1989: 61-86.
4. Mochizuki M, Kuwabara T, McAllister C, Nussenblatt RB, Gery I. Adoptive transfer of experimental autoimmune uveoretinitis in rats: immunopathogenic mechanisms and histologic features. Invest Opthalmol Vis Sci 1985; 26:1-9.
5. Caspi RR, Roberge FG, McAllister CG et al. T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat. J Immunol 1986; 136:1928-33.
6. Gregerson DS, Obritsch WF, Fling SP, Cameron JD. T cell lines recognize peptide fragments of S-antigen and mediate experimental auto-immune uveoretinitis and pinealitis. J Immunol 1986; 136:2875-82.
7. Caspi RR, Roberge FG, Chan CC et al. A new model of autoimmune disease: experimental autoimmune uveoretinitis induced in mice with two different retinal antigens. J Immunol 1988; 140:1490-5.
8. Pepperberg DR, Okajima TL, Wiggert B et al. Molecular biology and physiological role in the visual cycle of rhodopsin. Mol Neurobiol 1993; 7:61-85.
9. Borst DE, Redmond TM, Elser JE et al. Interphotoreceptor retinoid-binding protein: gene characterization, protein repeat structure, and its evolution. J Biol Chem 1989; 264:1115-23.
10. Caspi RR, Grubbs BG, Chan CC, Chader GJ, Wiggert B. Genetic control of susceptibility to experimental autoimmune uveoretinitis in the mouse model: concomitant regulation by MHC and non-MHC genes. J Immunol 1992; 148:2384-9.
11. Caspi RR, Silver PB, Chan CC et al. Immunogenetics of experimental autoimmune uveoretinitis (EAU). Reg Immunol 1993; 6:20-23.
12. r haplotype. Invest Ophthalmol Vis Sci 1995; 36:946-54.
13. Allen PM, Matsueda DR, Evans RJ et al. Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope. Nature 1987; 327:713-7.
14. Ogasawara K, Wambua PP, Gotohda T, Onoé K. Modification of the T cell responsiveness to synthetic peptides by substituting amino acids on agretopes. Int Immunol 1989; 2:219-24.
15. Itoh Y, Ogasawara K, Takami K et al. Determination of amino acids on agretopes of pigeon cytochrome c-related peptides specifically bound to I-A allelic products. Eur J Immunol 1994; 24:76-83.
16. Ogasawara K, Maloy WE, Beverly B, Schwartz RH. Functional analysis of the antigenic structure of a minor T cell determinant from pigeon cytochrome c: evidence against an α-helical conformation. J Immunol 1989; 142:1448-56.
17. Stern LJ, Brown JH, Jardetzky TS et al. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 1994; 368:215-21.
18. Fremont DH, Henderickson WA, Marrack P, Kappler J. Structures of an MHC class II molecule with covalently bound single peptides. Science 1996; 272:1001-4.
19. Ghosh P, Amaya M, Mellins E, Wiley DC. The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3. Nature 1995; 378:457-62.
20. Schaeffer EL, Sette A, Johnson DL et al. Relative contribution of "determinant selection" and "holes in the T cell repertoire" to T-cell responses. Proc Natl Acad Sci USA 1989; 86:4649-53.
21. Ogasawara K, Onoé K. MHC-binding motifs and the design of peptide-based vaccines. Trends Microbiol 1993; 1:276-9.
22. Hirose S, Ogasawara K, Natori T et al. Regulation of experimental autoimmune uveilis in rats - separation of MHC and non-MHC gene effects. Clin Exp Immunol 1991; 86:419-25.
23. Dadaglio C, Nelson CA, Deck MB et al. Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody. Immunity 1997; 6:727-38.
24. Stanhope MJ, Czelusniak J, Si JS, Nickerson J, Goodman M. A molecular perspective on mammalian evolution from the gene encoding interphotoreceptor retinoid binding protein, with convincing evidence for bat monophyly. Mol Phylogenet Evol 1992; 1:148-60.
25. Griffith TS, Brunner T, Fletcher SM, Green DR, Ferguson TA. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 1995; 270:1189-92.