Curariform antagonists bind in different orientations to the nicotinic receptor ligand binding domain

Journal of Biological Chemistry

Volumn 278, Issue 34, 2003, Pages 32284-32291

  Wang, Hai Long ^a   Gao, Fan ^a   Bren, Nina ^a   Sine, Steven M ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY CHROMATOGRAPHY; COMPUTATIONAL METHODS; MOLECULAR ORIENTATION; MUSCLE; MUTAGENESIS;

QUATERNARY NITROGEN;

BIOCHEMISTRY;

CHOLINERGIC RECEPTOR; DIMETHYLTUBOCURARINE CHLORIDE; LYSINE; MUTANT PROTEIN; NEUROMUSCULAR BLOCKING AGENT; NICOTINIC RECEPTOR; NITROGEN; THREONINE; TUBOCURARINE CHLORIDE; TYROSINE;

ALPHA CHAIN; ARTICLE; CHEMICAL MUTAGENESIS; COMPETITIVE INHIBITION; CRYSTAL STRUCTURE; DRUG BINDING SITE; HUMAN; HUMAN CELL; LIGAND BINDING; MATHEMATICAL ANALYSIS; MOLECULAR DYNAMICS; MUSCLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; RECEPTOR AFFINITY;

ALKALOIDS; BINDING SITES; CELL LINE; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTATION; NEUROMUSCULAR NONDEPOLARIZING AGENTS; RECEPTORS, NICOTINIC;

EID: 0042357059     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M304366200     Document Type: Article

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