Targeted epidermal expression of mutant connexins 26(D66H) mimics true Vohwinkel syndrome and provides a model for the pathogenesis of dominant connexin disorders

Human Molecular Genetics

Volumn 12, Issue 14, 2003, Pages 1737-1744

  Bakirtzis, George ^a   Choudhry, Rukhsana ^a   Assen, Trond ^a   Shore, Leonard ^b   Brown, Ken ^b   Bryson, Sheila ^b   Forrow, Stephen ^b   Tetley, Laurence ^a   Finbow, Malcolm ^c   Greenhalgh, David ^a   Hodgins, Malcolm ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c GLASGOW CALEDONIAN UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 26; CONNEXIN 30; GAP JUNCTION PROTEIN; KERATIN; LORICRIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; ELECTRON MICROSCOPY; EPIDERMIS CELL; GAP JUNCTION; GENE EXPRESSION; GENE INSERTION; GENE MUTATION; KERATODERMA; MICROSCOPY; MOUSE; MULTIPLE MALFORMATION SYNDROME; NICK END LABELING; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SKIN DISEASE; TRANSGENIC MOUSE; UPREGULATION; VOHWINKLE SYNDROME;

ANIMALS; CONNEXINS; EPIDERMIS; GENES, DOMINANT; MICE; MICE, TRANSGENIC; PROMOTER REGIONS (GENETICS); SKIN ABNORMALITIES;

ANIMALIA; INSERTION SEQUENCES; MUS MUSCULUS;

EID: 0042309578     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddg183     Document Type: Article

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