Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: Challenging the gene dosage effect hypothesis (Part IV)

Amino Acids

Volumn 25, Issue 1, 2003, Pages 41-47

  Cheon, M S ^a   Shim, K S ^a   Kim, S H ^a   Hara, A ^b   Lubec, Gert ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Carbonyl reductase 1; Chromosome 21; Coxsackievirus and adenovirus receptor; Down syndrome; Interferon ; Receptor; Trefoil factor

Indexed keywords

ALPHA INTERFERON RECEPTOR; CARBONYL REDUCTASE 1; COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR; GENE PRODUCT; TREFOIL FACTOR 1; TREFOIL FACTOR 2; TREFOIL FACTOR 3; TREFOIL PEPTIDE; UNCLASSIFIED DRUG; VIRUS RECEPTOR;

ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; CHROMOSOME 21; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN SYNDROME; FEMALE; FETUS; GENE DOSAGE; GENE OVEREXPRESSION; GENE SEQUENCE; GENOTYPE PHENOTYPE CORRELATION; HUMAN; HUMAN TISSUE; HYPOTHESIS; MENTAL DEFICIENCY; PRIORITY JOURNAL; SECOND TRIMESTER PREGNANCY; TRISOMY 21; WESTERN BLOTTING;

ADENOVIRIDAE; COXSACKIEVIRUS; LOTUS;

EID: 0042268004     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-003-0009-9     Document Type: Article

References (48)

1. Abramovich C, Ratovitski E, Lundgren E, Revel M (1994) Identification of mRNAs encoding two different soluble forms of the human interferon alpha-receptor. FEBS Lett 338: 295-300
2. Balcz B, Kirchner L, Cairns N, Fountoulakis M, Lubec G (2001) Increased brain protein levels of carbonyl reductase and alcohol dehydrogenase in Down syndrome and Alzheimer's disease. J Neural Transm [Suppl 61]: 193-201
3. Bergelson JM, Cunningham JA, Droguett G, Kurt-Jones EA, Krithivas A, Hong JS, Horwitz MS, Crowell RL, Finberg RW (1997) Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science 275: 1320-1323
4. Bergelson JM, Krithivas A, Celi L, Droguett G, Horwitz MS, Wickham T, Crowell RL, Finberg RW (1998) The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses. J Virol 72: 415-419
5. Bernal RM, Sharma S, Gardner BK, Douglas JT, Bergelson JM, Dubinett SM, Batra RK (2002) Soluble coxsackievirus adenovirus receptor is a putative inhibitor of adenoviral gene transfer in the tumor milieu. Clin Cancer Res 8: 1915-1923
6. Bork P (1993) A trefoil domain in the major rabbit zona pellucida protein. Protein Sci 2: 669-670
7. Busciglio J, Yankner BA (1995) Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro. Nature 378: 776-779
8. Chen YH, Lu Y, De Plaen IG, Wang LY, Tan XD (2000) Transcription factor NF-kB signals antianoikic function of trefoil factor 3 in intestinal epithelial cells. Biochem Biophys Res Commun 274: 576-582
9. Cheon MS, Bajo M, Kim SH, Claudio JO, Stewart AK, Patterson D, Kruger WD, Kondoh H, Lubec G (2003a) Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: challenging the gene dosage effect hypothesis (Part II). Amino Acids 24: 119-125
10. Cheon MS, Kim SH, Ovod V, Kopitar Jerala N, Morgan JI, Hatefi Y, Ijuin T, Takenawa T, Lubec G (2003b) Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: challenging the gene dosage effect hypothesis (Part III). Amino Acids 24: 127-134
11. Cohen CJ, Shieh JT, Pickles RJ, Okegawa T, Hsieh JT, Bergelson JM (2001) The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction. Proc Natl Acad Sci USA 98: 15191-15196
12. Colamonici O, Yan H, Domanski P, Handa R, Smalley D, Mullersman J, Witte M, Krishnan K, Krolewski J (1994) Direct binding to and tyrosine phosphorylation of the alpha subunit of the type 1 interferon receptor by p135tyk2 tyrosine kinase. Mol Cell Biol 14: 8133-8142
13. Cutrone EC, Langer JA (1997) Contributions of cloned type I interferon receptor subunits to differential ligand binding. FEBS Lett 404: 197-202
14. Engidawork E, Balic N, Fountoulakis M, Dierssen M, Greber-Platzer S, Lubec G (2001) β-Amyloid precursor protein, ETS-2 and collagen alpha 1 (VI) chain precursor, encoded on chromosome 21, are not over-expressed in fetal Down syndrome: further evidence against gene dosage effect. J Neural Transm [Suppl 61]: 335-346
15. Fechner H, Haack A, Wang H, Wang X, Eizema K, Pauschinger M, Schoemaker R, Veghel R, Houtsmuller A, Schultheiss HP, Lamers J, Poller W (1999) Expression of coxsackie adenovirus receptor and alpha-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers. Gene Ther 6: 1520-1535
16. Gauzzi MC, Barbieri G, Richter MF, Uze G, Ling L, Fellous M, Pellegrini S (1997) The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor. Proc Natl Acad Sci USA 94: 11839-11844
17. Goldman LA, Zafari M, Cutrone EC, Dang A, Brickelmeier M, Runkel L, Benjamin CD, Ling LE, Langer JA (1999) Characterization of anti-human IFNAR-1 monoclonal antibodies: epitope localization and functional analysis. J Interferon Cytokine Res 19: 15-26
18. Greber-Platzer S, Schatzmann-Turhani D, Cairns N, Balcz B, Lubec G (1999) Expression of the transcription factor ETS2 in brain of patients with Down syndrome-evidence against the overexpression-gene dosage hypothesis. J Neural Transm [Suppl 57]: 269-281
19. Gulesserian T, Engidawork E, Fountoulakis M, Lubec G (2001) Antioxidant proteins in fetal brain: superoxide dismutase-1 (SOD-1) protein is not overexpressed in fetal Down syndrome. J Neural Transm [Suppl 61]: 71-84
20. Gulesserian T, Kim SH, Fountoulakis M, Lubec G (2002) Aberrant expression of centractin and capping proteins, integral constituents of the dynactin complex, in fetal Down syndrome brain. Biochem Biophys Res Commun 291: 62-67
21. Hitora M, Awatsuji H, Sugihara Y, Miyashita S, Furukawa Y, Hayashi K (1995) Expression of pS2 gene in rat brain. Biochem Mol Biol Int 5: 1079-1084
22. Hoffmann W, Jagla W (2002) Cell type specific expression of secretory TFF peptides: Colocalization with mucin and synthesis in the brain. Int Rev Cyto 213: 147-181
23. Hoffmann W, Jagla W, Wiede A (2001) Molecular medicine of TFF-peptides: from gut to brain. Histol Histopathol 16: 319-334
24. Honda T, Saitoh H, Masuko M, Katagiri-Abe T, Tominaga K, Kozakai I, Kobayashi K, Kumanishi T, Watanabe YG, Odani S, Kuwano R (2000) The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain. Brain Res Mol Brain Res 77: 19-28
25. Ishikura S, Yamamto Y, Matsuura K, Wei J, Hodes ME, Hara A (1998) Properties and tissue distribution of mouse monomeric carbonyl reductase. Biol Pharm Bull 21: 879-881
26. Jagla W, Wiede A, Dietzmann K, Rutkowski K, Hoffmann W (2000) Colocalization of TFF3 peptide and oxytocin in the human hypothalamus. FASEB J 14: 1126-1131
27. Kinoshita T, Taupin DR, Itoh H, Podolsky DK (2000) Distinct pathways of cell migration and antiapoptotic response to epithelial injury: Structure-function analysis of human intestinal trefoil factor. Mol Cell Biol 20: 4680-4690
28. Lalani EN, Willams R, Jayaram Y, Gilbert C, Chaudhary KS, Sku LS, Koumarianou A, Playford R, Stamp GWH (1999) Trefoil factor-2, human spasmolytic polypeptide, promotes branching morphogenesis in MCF-7 cells. Lab Invest 79: 537-546
29. Lemieux N, Malfoy B, Forrest GL (1993) Human carbonyl reductase (CBR) localized to band 21q22.1 by high-resolution fluorescence in situ hybridization displays gene dosage effects in trisomy 21 cells. Genomics 15: 169-172
30. Ling LE, Zafari M, Reardon D, Brickelmeier M, Goelz SE, Benjamin CD (1995) Human type I interferon receptor, IFNAR, is a heavily glycosylated 120-130 kD membrane protein. J Interferon Cytokine Res 15: 55-61
31. Marks A, O'Hanlon D, Lei M, Percy ME, Becker LE (1996) Accumulation of S100 beta mRNA and protein in cerebellum during infancy in Down syndrome and control subjects. Brain Res Mol Brain Res 36: 343-348
32. May FEB, Semple JI, Newton JL, Westley B (2000) The human two domain trefoil protein, TFF2, is glycosylated in vivo in the stomach. Gut 46: 454-459
33. Novick D, Cohen B, Rubinstein M (1992) Soluble interferon-alpha receptor molecules are present in body fluids. FEBS Lett 314: 445-448
34. Odetti P, Angelini G, Dapino D, Zaccheo D, Garibaldi S, Dagna-Bricarelli F, Piombo G, Perry G, Smith M, Traverso N, Tabaton M (1998) Early glycoxidation damage in brains from Down's syndrome. Biochem Biophys Res Commun 243: 849-851
35. Pestka S, Langer JA, Zoon KC, Samuel CE (1987) Interferons and their actions. Annu Rev Biochem 56: 727-777
36. Probst JC, Skutella T, Mueller-Schmid A, Jirikowski GF, Hoffmann W (1995) Molecular and cellular analysis of rP1.B in the rat hypothalamus: In situ hybridization and immunohistochemistry of a new P-domain neuropeptide. Mol Brain Res 33: 269-276
37. Taub JW, Huang X, Matherly LH, Stout ML, Buck SA, Massey GV, Becton DL, Chang MN, Weinstein HJ, Ravindranath Y (1999) Expression of chromosome 21-localized genes in acute myeloid leukemia: differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin. Blood 94: 1393-1400
38. Taupin DR, Kinoshita K, Podolsky DK (2000) Intestinal trefoil factor confers colonic epithelial resistance to apoptosis. Proc Natl Acad Sci USA 97: 799-804
39. Thoelen I, Magnusson C, Tagerud S, Polacek C, Lindberg M, Van Ranst M (2001) Identification of alternative splice products encoded by the human coxsackie-adenovirus receptor gene. Biochem Biophys Res Commun 287: 216-222
40. Velazquez L, Fellous M, Stark GR, Pellegrini S (1992) A protein tyrosine kinase in the interferon alpha/beta signaling pathway. Cell 70: 313-322
41. Weitzdoerfer R, Dierssen M, Fountoulakis M, Lubec G (2001) Fetal life in Down syndrome starts with normal neuronal density but impaired dendritic spines and synaptosomal structure. J Neural Transm [Suppl 61]: 59-70
42. Wermuth B (1982) Human carbonyl reductases. Prog Clin Biol Res 114: 261-274
43. Wermuth B (1985) Aldo-keto reductases. Prog Clin Biol Res 174: 209-230
44. Wiede A, Jagla W, Welte T, Koehnlein T, Busk H, Hoffmann W (1999) Localization of TFF3, a new mucus-associated peptide of the human respiratory tract. Am J Respir Crit Care Med 159: 1330-1335
45. Wirth H, Wermuth B (1992) Immunohistochemical localization of carbonyl reductase in human tissues. J Histochem Cytochem 40: 1857-1863
46. Xu R, Crowell RL (1996) Expression and distribution of the receptors for coxsackievirus B3 during fetal development of the Balb/c mouse and of their brain cells in culture. Virus Res 46: 157-170
47. Xu R, Mohanty JG, Crowell RL (1995) Receptor proteins on newborn Balb/c mouse brain cells for coxsackievirus B3 are immunologically distinct from those on HeLa cells. Virus Res 35: 323-340
48. Yamada T, Yamanaka I (1995) Microglial localization of alpha-interferon receptor in human brain tissues. Neurosci Lett 189: 73-76