Second-site suppressor mutations for the serine 202 to phenylalanine substitution within the interdomain loop of the tetracycline efflux protein Tet(c)

Journal of Biological Chemistry

Volumn 278, Issue 31, 2003, Pages 28588-28592

  Sapunaric, Frederic M ^b   Levy, Stuart B ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; MUTAGENESIS; PROTEINS; SUBSTITUTION REACTIONS;

SUPPRESSOR MUTATIONS;

BIOCHEMISTRY;

AMINO ACID; HYDROXYLAMINE; MEMBRANE PROTEIN; NITROSOGUANIDINE; PHENYLALANINE; SERINE; TETRACYCLINE; TETRACYCLINE EFFLUX PROTEIN TETC; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOPLASM; ESCHERICHIA COLI; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BLOTTING, WESTERN; CELL MEMBRANE; ESCHERICHIA COLI; GENE EXPRESSION; GENES, SUPPRESSOR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTAGENESIS, SITE-DIRECTED; PHENYLALANINE; PROTEIN STRUCTURE, SECONDARY; REPRESSOR PROTEINS; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP; TETRACYCLINE; TETRACYCLINE RESISTANCE;

ESCHERICHIA COLI; NEGIBACTERIA; PROKARYOTA;

EID: 0042208058     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302658200     Document Type: Article

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