Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia

Journal of Biological Chemistry

Volumn 278, Issue 31, 2003, Pages 29024-29030

  Jones, Christopher ^a   Hammer, Robert E ^a,b   Li, Wei Ping ^b   Cohen, Jonathan C ^a,b   Hobbs, Helen H ^a,b   Herz, Joachim ^a,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHOLESTEROL; CYTOLOGY; GENES; IMMUNOLOGY;

ENDOCYTOSIS; FIBROBLASTS;

PROTEINS;

ADAPTOR PROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARH GENE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENDOCYTOSIS; GENE; HYPERCHOLESTEROLEMIA; IMMUNOLOCALIZATION; LIVER CELL; METABOLIC CLEARANCE RATE; MOUSE; NONHUMAN; PLASMA CLEARANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CENTRIFUGATION, DENSITY GRADIENT; CHOLESTEROL; CHOLESTEROL, DIETARY; CHOLESTEROL, LDL; ENDOCYTOSIS; HYPERCHOLESTEROLEMIA; HYPERLIPOPROTEINEMIA TYPE II; IODINE RADIOISOTOPES; LIPOPROTEINS, LDL; LIVER; METABOLIC CLEARANCE RATE; MICE; MICE, KNOCKOUT; RECEPTORS, LDL;

ANIMALIA;

EID: 0042206621     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M304855200     Document Type: Article

References (44)

1. Osono, Y., Woollett, L. A., Herz, J., and Dietschy, J. M. (1995) J. Clin. Invest. 95, 1124-1132
2. Goldstein,J.,Hobbs,H., and Brown, M. (2001) in The Metabolic and Molecular Bases oflnherited Disease (Scriver, C., Beaudet, A., Sly, W., and Valle, D., eds) Vol. II, 8th ed., pp. 2683-2913, McGraw-Hill Inc., New York
3. Goldstein, J. L., and Brown, M. S. (2001) Science 292, 1310-1312
4. Garcia, C. K., Wilund, K., Arca, M., Zuliani, G., Fellin, R., Maioli, M., Calandra, S., Bertolini, S., Cossu, F., Grishin, N., Barnes, R., Cohen, J. C., and Hobbs, H. H. (2001) Science 292, 1394 -1398
5. Wilund, K. R., Yi, M., Campagna, F., Arca, M., Zuliani, G., Fellin, R., Ho, Y. K., Garcia, J. V., Hobbs, H. H., and Cohen, J. C. (2002) Hum. Mol. Genet. 11, 3019-3030
6. Zuliani, G., Arca, M., Signore, A., Bader, G., Fazio, S., Chianelli, M., Bellosta, S., Campagna, F., Montali, A., Maioli, M., Pacifico, A., Ricci, G., and Fellin, R. (1999) Arterioscler. Thromb. Vasc. Biol. 19, 802-809
7. Norman, D., Sun, X.-M., Bourbon, M., Knight, B. L., Naoumova, R. P., and Soutar, A. K. (1999) J. Clin. Invest. 104, 619-628
8. Arca, M., Zuliani, G., Wilund, K., Campagna, F., Fellin, R., Bertolini, S., Calandra, S., Rieci, G., Glorioso, N., Maioli, M., Pintus, P., Carru, C., Cossu, F., Cohen, J., and Hobbs, H. H. (2002) Lancet 359, 841-847
9. Zuliani, G., Vigna, G. B., Corsini, A., Maioli, M., Romagnoni, F., and Fellin, R. (1995) Eur. J. Clin. Invest. 25, 322-331
10. He, G., Gupta, S., Yi, M., Michaely, P., Hobbs, H. H., and Cohen, J. C. (2002) J. Biol. Chem. 277, 44044-44049
11. Mishra, S. K., Watkins, S. C., and Traub, L. M. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 16099-16104
12. Forman-Kay, J. D., and Pawson, T. (1999) Curr. Opin. Struct. Biol. 9, 690-695
13. Yan, K. S., Kuti, M., and Zhou, M.-M. (2002) FEBS Lett. 513, 67-70
14. Chen, W. J, Goldstein, J. L., and Brown, M. S. (1990) J. Biol. Chem. 265, 3116-3123
15. Davis, C. G., Lehrman, M. A., Russell, D. W., Anderson, R. G., Brown, M. S., and Goldstein, J. L. (1986) Cell 45, 15-24
16. Garcia-Garcia, A. B., Real, J. T., Puig, O., Cebolla, E., Marin-Garcia, P., Martinez Ferrandis, J. I, Garcia-Sogo, M., Civera, M., Ascaso, J., F., Carmena, R., Armengod, M. E., and Chaves, F. J. (2001) Hum. Mutat. 18, 458-459
17. Trommsdorff, M., Borg, J. P., Margolis, B., and Herz, J. (1998) J. Biol. Chem. 273, 33556-33560
18. Trommsdorff, M., Gotthardt, M., Hiesberger, T., Shelton, J., Stockinger, W., Nimpf, J., Hammer, R. E., Richardson, J. A., and Herz, J. (1999) Cell 97, 689-701
19. Willnow, T. E., Sheng, Z., Ishibashi, S., and Herz, J. (1994) Science 264, 1471-1474
20. Rohlmann, A., Gotthardt, M., Hammer, R. E., and Herz, J. (1998) J. Clin. Invest. 101, 689-695
21. Sambrook, J., and Russel, D. W. (2001) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
22. Goldstein, J. L., Basu, S. K., and Brown, M. S. (1983) Methods Enzymol. 98, 241-260
23. Ishibashi, S., Brown, M. S., Goldstein, J. L., Gerard, R. D., Hammer, R. E., and Herz, J. (1993) J. Clin. Invest. 92, 883-893
24. Fraker, P. J., and Speck, J. C., Jr. (1978) Biochem. Biophys. Res. Commun. 80, 849-857
25. Herz, J., Hamann, U., Rogne, S., Myklebost, O., Gausepohl, H., and Stanley. K. K. (1988) EMBO J. 7, 4119-4127
26. Russell, D. W., Schneider, W. J., Yamamoto, T., Luskey, K. L., Brown, M. S., and Goldstein, J. L. (1984) Cell 37, 577-585
27. Gotthardt, M., Hammer, R. E., Hubner, N., Monti, J., Witt, C. C., McNabb, M., Richardson, J. A., Granzier, H, Labeit, S., and Herz, J. (2003) J. Biol. Chem. 278, 6059-6065
28. Soriano, P., Montgomery, C., Geske, R., and Bradley, A. (1991) Cell 64, 693-702
29. Mansour, S. L., Thomas, K. R., and Capecchi, M. R. (1988) Nature 336, 348-352
30. Willnow, T. E., and Herz, J. (1994) Methods Cell Biol. 43, 305-334
31. Plump, A. S., Smith, J. D., Hayek, T., Aalto-Setala, K., Walsh, A., Verstuyft, J. G., Rubin, E. M., and Breslow, J. L. (1992) Cell 71,343-353
32. Choi, S. Y., and Cooper, A. D. (1993) J. Biol. Chem. 268, 15804-15811
33. Gotthardt, M, Trommsdorff, M., Nevitt, M. F., Shelton, J., Richardson, J. A., Stockinger, W., Nimpf, J., and Herz, J. (2000) J. Biol. Chem. 275, 25616-25624
34. Stockinger, W., Sailler, B., Strasser, V., Recheis, B., Fasching, D., Kahr, L., Schneider, W. J., and Nimpf, J. (2002) EMBO J. 21, 4259-4267
35. Morris, S. M., Tallquist, M. D., Rock, C. O., and Cooper, J. A. (2002) EMBO J. 21, 1555-1564
36. Kowal, R. C., Herz, J., Weisgraber, K. H., Mahley, R. W., Brown, M. S., and Goldstein, J. L. (1990) J. Biol. Chem. 265, 10771-10779
37. Twisk, J., Gillian-Daniel, D. L., Tebon, A., Wang, L., Barrett, P. H. R., and Attie, A. D. (2000) J. Clin. Invest. 105, 521-532
38. Koivisto, U. M., Hubbard, A. L., and Mellman, I. (2001) Cell 105, 575-585
39. Eden, E. R., Patel, D. D., Sun, X. M., Burden, J. J., Themis, M., Edwards, M., Lee, P., Neuwirth, C., Naoumova, R. P., and Soutar, A. K. (2002) J. Clin. Invest. 110, 1695-1702
40. Li, Y., Lu, W., Marzolo, M. P., and Bu, G. (2001) J. Biol. Chem. 276, 18000-18006
41. Rohlmann, A., Gotthardt, M., Willnow, T. E., Hammer, R. E., and Herz, J. (1996) Nature Biotechnol. 14, 1562-1565
42. Somsel Rodman, J., and Wandinger-Ness, A. (2000) J. Cell Sci. 113, 183-192
43. Gotthardt, M., Hammer, R. E., Hübner, N., Monti, J., Witt, C. C., McNabb, M., Richardson, J. A., Granzier, H., Labeit, S., and Herz, J. (2003) J. Biol. Chem. 278, 6059-6065
44. Yokode, M., Hammer, R. E., Ishibashi, S., Brown, M. S., and Goldstein, J. L. (1990) Science 250, 1273-1275