Oxidized low-density lipoprotein induces calpain-dependent cell death and ubiquitination of caspase 3 in HMEC-1 endothelial cells

Biochemical Journal

Volumn 374, Issue 2, 2003, Pages 403-411

  Pörn Ares, M Isabella ^a   Saido, Takaomi C ^b   Andersson, Tommy ^a   Ares, Mikko P S ^c  

^a LUND UNIVERSITY   (Sweden)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

fodrin; Apoptosis; Bid; Calpain; Endothelial cells; Low density lipoprotein

Indexed keywords

CELLS; DNA; ENZYME INHIBITION; OXIDATION; PROTEINS;

PROTEOLYSIS;

BIOCHEMISTRY;

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CA 074 ME; CALPAIN; CALPASTATIN; CASPASE 3; CASPASE INHIBITOR; CATHEPSIN B INHIBITOR; ENZYME INHIBITOR; LOW DENSITY LIPOPROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PD 151746; PROTEIN BID; PROTEIN SUBUNIT; TERT BUTOXYCARBONYLASPARTYLMETHOXY FLUOROMETHYL KETONE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME MODIFICATION; HUMAN; HUMAN CELL; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UBIQUITINATION;

APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CALCIUM; CALPAIN; CARRIER PROTEINS; CASPASE 3; CASPASES; CELL LINE; DNA FRAGMENTATION; ENDOPEPTIDASES; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; GROWTH INHIBITORS; HUMANS; HYDROLYSIS; INTRACELLULAR FLUID; LIPOPROTEINS, LDL; MICROFILAMENT PROTEINS; OXIDATION-REDUCTION; PROTO-ONCOGENE PROTEINS C-BCL-2; UBIQUITIN;

EID: 0041829109     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021955     Document Type: Article

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