Autocrine FGF-2 is responsible for the cell density-dependent susceptibility to apoptosis of HUVEC: A role of a calpain inhibitor-sensitive mechanism

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 19, Issue 10, 1999, Pages 2323-2329

  Kinoshita, Mikio ^a   Shimokado, Kentaro ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Apoptosis; Cytoplasmic neutral protease; Endothelial cells; Endothelial integrity; Growth factors

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CALPASTATIN; PROTEASOME INHIBITOR; PROTEIN ANTIBODY; SCATTER FACTOR; SOMATOMEDIN C; VASCULOTROPIN;

APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL DENSITY; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN SECRETION; PROTEIN SYNTHESIS REGULATION;

EID: 0032879135     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.19.10.2323     Document Type: Article

References (44)

1. Reidy MA, Fingerle J, Lindner V. Factors controlling the development of arterial lesions after injury. Circulation. 1992;86(Suppl 6)III43-III46.
2. Sato Y, Rifkin DB. Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis. J Cell Biol. 1988;107:1199-1205.
3. Lindner V, Reidy MA. Expression of basic fibroblast growth factor and its receptor by smooth muscle cells and endothelium in injured rat arteries. An en face study. Circ Res. 1993;73:589-595.
4. Mitchinson MJ, Hardwick SJ, Bennett MR. Cell death in atherosclerotic plaques. Curr Opin Lipidol. 1996;7:324-329.
5. Araki S, Shimada Y, Kaji K, Hayashi H. Apoptosis of vascular endothelial cells by fibroblast growth factor deprivation. Biochem Biophys Res Commun. 1990;168:1194-1200.
6. Escargueil BI, Meilhac O, Pieraggi MT, Arnal JF, Salvayre R, Negre SA. Oxidized LDLs induce massive apoptosis of cultured human endothelial cells through a calcium-dependent pathway. Prevention by aurintricarboxylic acid. Arterioscler Thromb Vasc Biol. 1997;17:331-339.
7. Langley RE, Bump EA, Quartuccio SG, Medeiros D, Braunhut SJ. Radiation-induced apoptosis in microvascular endothelial cells. Br J Cancer. 1997;75:666-672.
8. Szabo C, Cuzzocrea S, Zingarelli B, O'Connor M, Salzman AL. Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. J Clin Invest. 1997;100: 723-735.
9. Hoyt DG, Mannix RJ, Gerritsen ME, Watkins SC, Lazo JS, Pitt BR, Integrins inhibit LPS-induced DNA strand breakage in cultured lung endothelial cells. Am J Physiol. 1996:L689-L694.
10. Slowik MR, De LL, Min W, Pober JS. Ceramide is not a signal for tumor necrosis factor-induced gene expression but does cause programmed cell death in human vascular endothelial cells. Circ Res. 1996;79:736-747.
11. Maier JA, Morelli D, Menard S, Colnaghi MI, Balsari A. Tumor-necrosis-factor-induced fibroblast growth factor-1 acts as a survival factor in a transformed endothelial cell line. Am J Pathol. 1996;149:945-952.
12. Varani J, Dame MK, Taylor CG, Sarma V, Merino R, Kunkel RG, Nunez G, Dixit VM. Age-dependent injury in human umbilical vein endothelial cells: relationship to apoptosis and correlation with a lack of A20 expression. Lab Invest. 1995;73:851-858.
13. Harada SM, Kinoshita M, Kamido H, Shimokado K. Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms. J Biol Chem. 1998;273: 9681-9687.
14. Yang W, deBono D. A new role for vascular endothelial growth factor and fibroblast growth factors: increasing endothelial resistance to oxidative stress. FEBS Lett. 1997;403:139-142.
15. Matsuzaki K, Yoshitake Y, Matuo Y, Sasaki H, Nishikawa K. Monoclonal antibodies against heparin-binding growth factor II/basic fibroblast growth factor that block its biological activity: invalidity of the antibodies for tumor angiogenesis. Proc Natl Acad Sci U S A. 1989;86:9911-9915.
16. Saito Y, Tsubuki S, Ito H, Kawashima S. The structure-function relationship between peptide aldehyde derivatives on initiation of neurite outgrowth in PC12h cells. Neurosci Lett. 1990;120:1-4.
17. Tsubuki S, Saito Y, Tomioka M, Ito H, Kawashima S. Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-leucine and tri-leucine. J Biochem (Tokyo). 1996;119:572-576.
18. Omura S, Fujimoto T, Otoguro K, Matsuzaki K, Moriguchi R, Tanaka H, Sasaki Y. Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells. J Antibiot (Tokyo). 1991;44:113-116.
19. Tamai M, Yokoo C, Murata M, Oguma K, Sota K, Sato E, Kanaoka Y. Efficient synthetic method for ethyl (+)-(2S,3S)-3-[(S)-3-methyl- 1-(3-methylbutylcarbamoyl) butylcarbamoyl]-2-oxiranecarb oxylate (EST), a new inhibitor of cysteine proteinases. Chem Pharm Bull (Tokyo). 1987;35: 1098-1104.
20. Bikfalvi A, Klein S, Pintucci G, Quarto N, Mignatti P, Rifkin DB, Differential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: possible intracellular signaling by the high molecular weight forms. J Cell Biol. 1995;129:233-243.
21. Gimbrone MA, Cotran RS, Folkman J. Human vascular endothelial cells in culture. Growth and DNA synthesis. J Cell Biol. 1974;60:673-684.
22. Rosl F. A simple and rapid method for detection of apoptosis in human cells. Nucleic Acids Res. 1992;20:5243.
23. Higaki M, Sakaue H, Ogawa W, Kasuga M, Shimokado K. Phosphatidylinositol 3-kinase-independent signal transduction pathway for platelet-derived growth factor-induced chemotaxis. J Biol Chem. 1996;271: 29342-29346.
24. Okamura K, Sato Y, Matsuda T, Hamanaka R, Ono M, Kohno K, Kuwano M. Endogenous basic fibroblast growth factor-dependent induction of collagenase and interleukin-6 in tumor necrosis factor-treated human microvascular endothelial cells. J Biol Chem. 1991;266:19162-19165.
25. Shimokado K, Umezawa K, Ogata J. Tyrosine kinase inhibitors inhibit multiple steps of the cell cycle of vascular smooth muscle cells. Exp Cell Res. 1995;220:266-273.
26. Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 1989; 246:1306-1309.
27. Bussolino F, Di Renzo MF, Ziehe M, Bocchietto E, Olivero M, Naldini L, Gaudino G, Tamagnaone L, Coffer A, Comoglio PM. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol. 1992;119:629-641.
28. King GL, Goodman AD, Buzney S, Moses A, Kahn CR. Receptors and growth promoting effects of insulin and insulin-like growth factors on cells bovine retinal capillaries and aorta. J Clin Invest. 1985;75:1028-1036.
29. Renko M, Quarto N, Morimot T, Rifkin DB. Nuclear and cytoplasmic localization of different basic fibroblast growth factor species. J Cell Physiol. 1990;144:108-114.
30. Yu ZX, Biro S, Fu YM, Sanchez J, Smale G, Sasse J, Ferrans VJ, Casscells W. Localization of basic fibroblast growth factor in bovine endothelial cells: immunohistochemical and biochemical studies. Exp Cell Res. 1993;204: 247-259.
31. Coux O, Tanaka K, Goldberg AL. Structure and functions of the 20S and 26S proteasomes. Annu Rev Biochem. 1996;65:801-847.
32. Suzuki K, Saido TC, Hirai S. Modulation of cellular signals by calpain. Ann N Y Acad Sci. 1992;674:218-227.
33. Tamm I, Kikuchi T, Zychlinsky A. Acidic and basic fibroblast growth factors are survival factors with distinctive activity in quiescent BALB/c 3T3 murine fibroblasts. Proc Natl Acad Sci U S A. 1991;88:3372-3376.
34. Fuks Z, Persaud RS, Alfieri A, McLoughlin M, Ehleiter D, Schwartz JL, Seddon AP, Cordon CC, Haimovitz FA. Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo. Cancer Res. 1994;54:2582-2590.
35. Prats H, Kaghad M, Prats AC, Klagsbrun M, Lelias JM, Liauzun P, Chalon P, Tauber JP, Amalric F, Smith JA, Caput D. High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons. Proc Natl Acad Sci U S A. 1989;86:1836-1840.
36. Biro S, Yu ZX, Fu YM, Smale G, Sasse J, Sanchez J, Ferrans VJ, Casscells W. Expression and subcellular distribution of basic fibroblast growth factor are regulated during migration of endothelial cells. Circ Res. 1994;74: 485-494.
37. Moffett J, Kratz E, Florkiewicz R, Stachowiak MK. Promoter regions involved in density-dependent regulation of basic fibroblast growth factor gene expression in human astrocytic cells. Proc Natl Acad Sci U S A. 1996; 93:2470-2475.
38. Ku PT, D'Amore PA. Regulation of basic fibroblast growth factor (bFGF) gene and protein expression following its release from sublethally injured endothelial cells. J Cell Biochem. 1995;58:328-343.
39. Yuan Y, Dopheide SM, Ivanidis C, Salem HH, Jackson SP. Calpain regulation of cytoskeletal signaling complexes in von Willebrand factor-stimulated platelets. J Biol Chem. 1997;272:21847-21854.
40. Yang Y, Liu ZH, Ware CF, Ashwell JD. A cysteine protease inhibitor prevents activation-induced T-cell apoptosis and death of peripheral blood cells from human immunodeficiency virus-infected individuals by inhibiting upregulation of Fas ligand. Blood. 1997;89:550-557.
41. Jensen TJ, Loo MA, Pind S, Williams DB, Goldberg AL, Riordan JR. Multiple proteolytic systems, including the proteasome, contribute to CFTR processing. Cell. 1995;83:129-135.
42. Fujitani K, Kambayash J, Sakon M, Ohmi SI, Kawashima S, Yukawa M, Yano Y, Miyoshi H, Ikeda M, Shinoki N, Monden M. Identification of mu-, m-calpains and calpastatin and capture of mu- calpain activation in endothelial cells. J Cell Biochem. 1997;66:197-209.
43. Saido TC, Sorimachi H, Suzuki K. Calpain: new perspectives in molecular diversity and physiological-pathological involvement. FASEB J. 1994;48: 814-822.
44. McCelland P, Lash JA, Hathaway DR. Identification of major autolytic cleavage sites in the regulatory subunit of vascular calpain II. A comparison of partial amino-terminal sequences to deduced sequence from complementary DNA. J Biol Chem. 1989;264:17428-17431.