Efficacy of amodiaquine alone and combined with sulfadoxine-pyrimethamine and of sulfadoxine pyrimethamine combined with artesunate

American Journal of Tropical Medicine and Hygiene

Volumn 68, Issue 6, 2003, Pages 743-747

  Rwagacondo, Claude E ^a   Niyitegeka, Francois ^a   Sarushi, Joseph ^a   Karema, Corine ^a   Mugisha, Veronique ^a   Dujardin, Jean Claude ^b   Van Overmeir, Chantal ^b   Van Den Ende, Jef ^b   D'Alessandro, Umberto ^b  

^a National Malaria Control Program   (Rwanda)

^b INSTITUTE OF TROPICAL MEDICINE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; ARTESUNATE; CHLOROQUINE; FANSIDAR; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; PYRIMETHAMINE; SESQUITERPENE; SULFADOXINE; SULFADOXINE-PYRIMETHAMINE;

AGRANULOCYTOSIS; APLASTIC ANEMIA; ARTICLE; CELL VOLUME; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; HEALTH CENTER; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALARIA; NEUTROPENIA; PLASMODIUM FALCIPARUM; PRESCHOOL CHILD; RWANDA; TREATMENT FAILURE; TREATMENT OUTCOME; TREATMENT PLANNING; ANIMAL; DRUG COMBINATION; DRUG EFFECT; FEMALE; HEALTH SERVICE; MALARIA FALCIPARUM; MALE; PARASITOLOGY; RURAL HEALTH CARE;

PLASMODIUM FALCIPARUM; PROTOZOA;

AMODIAQUINE; ANIMALS; ANTIMALARIALS; ARTEMISININS; CHILD, PRESCHOOL; DRUG COMBINATIONS; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; INFANT; MALARIA, FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; PYRIMETHAMINE; RURAL HEALTH SERVICES; RWANDA; SESQUITERPENES; SULFADOXINE; TREATMENT OUTCOME; URBAN HEALTH SERVICES;

EID: 0041736445     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2003.68.743     Document Type: Article

References (23)

1. World Health Organization, 1993. Implementation of the Global Malaria Control Strategy. Report of a WHO Study Group on the implementation of the Global Plan of Action on Malaria Control 1993-2000. Geneva: World Health Organization.
2. Shretta R, Omumbo J, Rapuoda B, Snow RW, 2000. Using evidence to change antimalarial drug policy in Kenya. Trop Med Int Health 5: 755-764.
3. Trape JF, 2001. The public health impact of chloroquine resistance in Africa. Am J Trop Med Hyg 64 (Suppl 1-2): 12-17.
4. Bloland PB, Lackritz EM, Kazembe PN, Were JB, Steketee R, Campbell CC, 1993. Beyond chloroquine: implications of drug resistance for evaluating malaria therapy efficacy and treatment policy in Africa. J Infect Dis 167: 932-937.
5. White NJ, Olliaro PL, 1996. Strategies for the prevention of antimalarial drug resistance: rationale for combination chemotherapy for malaria. Parasitol Today 12: 399-401.
6. White NJ, 1998. Preventing antimalarial drug resistance through combinations. Drug Res Updates 1: 3-9.
7. White NJ, 1999. Antimalaria drug resistance and combination chemotherapy. Philos Trans R Soc Lond B Biol Sci 354: 739-749.
8. Nosten F, van Vugt M, Price R, Luxemburger C, Thway KL, Brockman A, McGready R, ter Kuile F, Looareesuwan S, White NJ, 2000. Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand: a prospective study. Lancet 356: 297-302.
9. White NJ, Olliaro P, 1998. Artemisinin and derivatives in the treatment of uncomplicated malaria. Med Trop (Mars) 58 (Suppl 3): 54-56.
10. Hastings IM, D'Alessandro U, 2000. Modelling a predictable disaster: the rise and spread of drug resistant malaria. Parasitol Today 16: 340-347.
11. Ministère de la Santé, 1999. Rapport Annuel 1998 du Ministère de la Santé. Kigali, Rwanda.
12. Warrell DA, Molyneux ME, Beales PF, 1990. Severe and complicated malaria. Trans R Soc Trop Med Hyg 84 (Supp. 2): 1-65.
13. Irion A, Felger I, Abdulla S, Smith T, Mull R, Tanner M, Hatz C, Beck HP, 1998. Distinction of recrudescences from new infection by PCR-RFLP analysis in a comparative trial of CGP 56 697 and chloroquine in Tanzanian children. Trop Med Int Health 3: 490-497.
14. World Health Organization, 1996. Assessment of Therapeutic Efficacy of Antimalarial Drugs For Uncomplicated Falciparum Malaria in Areas with Intense Transmission. Geneva: World Health Organization. WHO/MAL/96.1077.
15. Doherty JF, Sadiq AD, Bayo L, Alloueche A, Olliaro P, Milligan P, von Seidlein L, Pinder M, 1999. A randomized safety and tolerability trial of artesunate plus sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine alone for the treatment of uncomplicated malaria in Gambian children. Trans R Soc Trop Med Hyg 93: 543-546.
16. von Seidlein L, Milligan P, Pinder M, Bojang K, Anyalebechi C, Gosling R, Coleman R, Ude JI, Sadiq A, Duraisingh M, Warhurst D, Alloueche A, Targett G, McAdam K, Greenwood B, Walraven G, Olliaro P, Doherty T, 2000. Efficacy of artesunate plus pyrimethamine-sulphadoxine for uncomplicated malaria in Gambian children: a double-blind, randomised, controlled trial. Lancet 355: 352-357.
17. McIntosh HM, 2002. Chloroquine and amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria (Cochrane Review). The Cochrane Library. Issue 3. Oxford: Update Software.
18. Staedke SG, Kamya MR, Dorsey G, Gasasira A, Ndeezi G, Charlebois ED, Rosenthal PJ, 2001. Amodiaquine, sulfadoxine/pyrimethamine, and combination therapy for the treatment of uncomplicated falciparum malaria in Kampala, Uganda: a randomised trial. Lancet 358: 368-374.
19. Wongsrichanalai C, Thimasarn K, Sirichaisinthop J, 2000. Antimalarial drug combination policy: a caveat. Lancet 355: 2245-2247.
20. Magesa SM, Mdira KY, Babiker HA, Alifrangis M, Farnert A, Simonsen PE, Bygbjerg IC, Walliker D, Jakobsen PH, 2002. Diversity of Plasmodium falciparum clones infecting children living in a holoendemic area in north-eastern Tanzania. Acta Trop 84: 83-92.
21. Greenwood B, 2002. The molecular epidemiology of malaria. Trop Med Int Health 7: 1012-1021.
22. Olliaro P, Mussano P, 2002. Amodiaquine for treating malaria (Cochrane Review). The Cochrane Library. Issue 3. Oxford: Update Software.
23. Adjuik M, Agnamey P, Babiker A, Borrman S, Brasseur P, Cisse M, Cobelens F, Diallo S, Faucher JF, Garner P, Gikunda S, Kremsner PG, Krishna S, Lell B, Loolpapit M, Matsiegui P-B, Missinou MA, Mwanza J, Ntoumi F, Olliaro P, Osimbo P, Rezbach P, Some E, Taylor WRJ, 2002. Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children: a randomised, multicentre trial. Lancet 359: 1365-1372.