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Volumn 25, Issue 1, 2003, Pages 27-37

Ixodes ricinus tick salivary gland extract inhibits IL-10 secretion and CD69 expression by mitogen-stimulated murine splenocytes and induces hyporesponsiveness in B lymphocytes

Author keywords

B lymphocytes; IL 10; Immunosuppression; Ixodes ricinus; Salivary glands; Tick

Indexed keywords

CD69 ANTIGEN; CONCANAVALIN A; INTERLEUKIN 10; LIPOCORTIN 5; LIPOPOLYSACCHARIDE; MITOGENIC AGENT; CELL EXTRACT; LEUKOCYTE ANTIGEN; T LYMPHOCYTE ANTIGEN;

EID: 0041626086     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.2003.00605.x     Document Type: Article
Times cited : (54)

References (37)
  • 1
    • 0035451704 scopus 로고    scopus 로고
    • Coinfecting deer-associated zoonoses. Lyme disease, babesiosis, and ehrlichiosis
    • Thompson C, Spielman A & Krause PJ. Coinfecting deer-associated zoonoses. Lyme disease, babesiosis, and ehrlichiosis. Clin Infect Dis 2001; 33: 676-685.
    • (2001) Clin Infect Dis , vol.33 , pp. 676-685
    • Thompson, C.1    Spielman, A.2    Krause, P.J.3
  • 2
    • 0035094607 scopus 로고    scopus 로고
    • Aspects of Lyme borreliosis in Europe
    • Weber K. Aspects of Lyme borreliosis in Europe. Eur J Clin Microbiol Infect Dis 2001; 20: 6-13.
    • (2001) Eur J Clin Microbiol Infect Dis , vol.20 , pp. 6-13
    • Weber, K.1
  • 3
    • 0039488442 scopus 로고    scopus 로고
    • Lyme disease - United States 2000
    • Anonymous. Lyme disease - United States 2000. Morbidity Mortality Weekly Report 2002; 51: 29-31.
    • (2002) Morbidity Mortality Weekly Report , vol.51 , pp. 29-31
  • 4
    • 0034046934 scopus 로고    scopus 로고
    • The immunomodulatory factors of bloodfeeding arthropod saliva
    • Gillespie RD, Mbow ML & Titus RG. The immunomodulatory factors of bloodfeeding arthropod saliva. Parasite Immunol 2000; 22: 319-331.
    • (2000) Parasite Immunol , vol.22 , pp. 319-331
    • Gillespie, R.D.1    Mbow, M.L.2    Titus, R.G.3
  • 5
    • 0032781224 scopus 로고    scopus 로고
    • Tick modulation of host immunity: An important factor in pathogen transmission
    • Wikel SK. Tick modulation of host immunity: an important factor in pathogen transmission. Int J Parasitol 1999; 29: 51-59.
    • (1999) Int J Parasitol , vol.29 , pp. 51-59
    • Wikel, S.K.1
  • 6
    • 0024315797 scopus 로고
    • Enhancement of virus transmission by tick salivary glands
    • Jones LD, Hodgson E & Nuttall PA. Enhancement of virus transmission by tick salivary glands. J General Virol 1989; 70: 1895-1898.
    • (1989) J General Virol , vol.70 , pp. 1895-1898
    • Jones, L.D.1    Hodgson, E.2    Nuttall, P.A.3
  • 7
    • 0033835741 scopus 로고    scopus 로고
    • Cytokines (IL-4 and IFN-gamma) and antibodies (IgE and IgG2a) produced in mice infected with Borrelia burgdorferi sensu stricto via nymphs of Ixodes ricinus ticks or syringe inoculations
    • Christe M, Rutti B & Brossard M. Cytokines (IL-4 and IFN-gamma) and antibodies (IgE and IgG2a) produced in mice infected with Borrelia burgdorferi sensu stricto via nymphs of Ixodes ricinus ticks or syringe inoculations. Parasitol Res 2000; 86: 491-496.
    • (2000) Parasitol Res , vol.86 , pp. 491-496
    • Christe, M.1    Rutti, B.2    Brossard, M.3
  • 8
    • 0030767838 scopus 로고    scopus 로고
    • Effects of Ixodes scapularis and Borrelia burgdorferi on modulation of the host immune response: Induction of a TH2 cytokine response in Lyme disease-susceptible (C3H/HeJ) mice but not in disease-resistant (BALB/c) mice
    • Zeidner N, Mbow ML, Dolan M, Massung R, Baca E & Piesman J. Effects of Ixodes scapularis and Borrelia burgdorferi on modulation of the host immune response: induction of a TH2 cytokine response in Lyme disease-susceptible (C3H/HeJ) mice but not in disease-resistant (BALB/c) mice. Infect Immun 1997; 65: 3100-3106.
    • (1997) Infect Immun , vol.65 , pp. 3100-3106
    • Zeidner, N.1    Mbow, M.L.2    Dolan, M.3    Massung, R.4    Baca, E.5    Piesman, J.6
  • 9
    • 0026914639 scopus 로고
    • Modulation of host-immune responses by ticks (Acari: Ixodidae): Effect of salivary gland extracts on host macrophages and lymphocyte cytokine production
    • Ramachandra RN & Wikel SK. Modulation of host-immune responses by ticks (Acari: Ixodidae): effect of salivary gland extracts on host macrophages and lymphocyte cytokine production. J Med Entomol 1992; 29: 818-826.
    • (1992) J Med Entomol , vol.29 , pp. 818-826
    • Ramachandra, R.N.1    Wikel, S.K.2
  • 10
    • 0028169440 scopus 로고
    • Saliva of the Lyme disease vector, Ixodes dammini, blocks cell activation by a nonprostaglandin E2-dependent mechanism
    • Urioste S, Hall LR, Telford SR & Titus RG. Saliva of the Lyme disease vector, Ixodes dammini, blocks cell activation by a nonprostaglandin E2-dependent mechanism. J Exp Med 1994; 180: 1077-1085.
    • (1994) J Exp Med , vol.180 , pp. 1077-1085
    • Urioste, S.1    Hall, L.R.2    Telford, S.R.3    Titus, R.G.4
  • 11
    • 0035723238 scopus 로고    scopus 로고
    • Anti-interleukin-8 activity of tick salivary gland extracts
    • Hajnicka V, Kocakova P, Slavikova M et al. Anti-interleukin-8 activity of tick salivary gland extracts. Parasite Immunol 2001; 23: 483-489.
    • (2001) Parasite Immunol , vol.23 , pp. 483-489
    • Hajnicka, V.1    Kocakova, P.2    Slavikova, M.3
  • 12
    • 0028106372 scopus 로고
    • Salivary gland extracts of partially fed Dermacentor reticulatus ticks decrease natural killer cell activity in vitro
    • Kubes M, Fuchsberger N, Labuda M, Zuffova E & Nuttall PA. Salivary gland extracts of partially fed Dermacentor reticulatus ticks decrease natural killer cell activity in vitro. Immunology 1994; 82: 113-116.
    • (1994) Immunology , vol.82 , pp. 113-116
    • Kubes, M.1    Fuchsberger, N.2    Labuda, M.3    Zuffova, E.4    Nuttall, P.A.5
  • 13
    • 0029584659 scopus 로고
    • Dermacentor andersoni: Salivary gland proteins suppressing T-lymphocyte responses to concanavalin A in vitro
    • Bergman DK, Ramachandra RN & Wikel SK. Dermacentor andersoni: salivary gland proteins suppressing T-lymphocyte responses to concanavalin A in vitro. Exp Parasitol 1995; 81: 262-271.
    • (1995) Exp Parasitol , vol.81 , pp. 262-271
    • Bergman, D.K.1    Ramachandra, R.N.2    Wikel, S.K.3
  • 14
    • 0035935651 scopus 로고    scopus 로고
    • Progress toward molecular characterization of ectoparasite modulation of host immunity
    • Wikel SK & Alarcon-Chaidez F. Progress toward molecular characterization of ectoparasite modulation of host immunity. Vet Parasitol 2001; 101: 275-287.
    • (2001) Vet Parasitol , vol.101 , pp. 275-287
    • Wikel, S.K.1    Alarcon-Chaidez, F.2
  • 15
    • 18444406853 scopus 로고    scopus 로고
    • Salp15, an Ixodes scapularis salivary protein, inhibits CD4(+) T cell activation
    • Anguita J, Ramamoorthi N, Hovius JW et al. Salp15, an Ixodes scapularis salivary protein, inhibits CD4(+) T cell activation. Immunity 2002; 16: 849-859.
    • (2002) Immunity , vol.16 , pp. 849-859
    • Anguita, J.1    Ramamoorthi, N.2    Hovius, J.W.3
  • 16
    • 0032981719 scopus 로고    scopus 로고
    • Successive tick infestations selectively promote a T-helper 2 cytokine profile in mice
    • Ferreira BR & Silva JS. Successive tick infestations selectively promote a T-helper 2 cytokine profile in mice. Immunology 1999; 96: 434-439.
    • (1999) Immunology , vol.96 , pp. 434-439
    • Ferreira, B.R.1    Silva, J.S.2
  • 17
    • 0032787091 scopus 로고    scopus 로고
    • Control of early viral and bacterial distribution and disease by natural antibodies
    • Ochsenbein AF, Fehr T, Lutz C et al. Control of early viral and bacterial distribution and disease by natural antibodies. Science 1999; 286: 2156-2159.
    • (1999) Science , vol.286 , pp. 2156-2159
    • Ochsenbein, A.F.1    Fehr, T.2    Lutz, C.3
  • 18
    • 0035313541 scopus 로고    scopus 로고
    • Identification of an IL-2 binding protein in the saliva of the Lyme disease vector tick, Ixodes scapularis
    • Gillespie RD, Dolan MC, Piesman J & Titus RG. Identification of an IL-2 binding protein in the saliva of the Lyme disease vector tick, Ixodes scapularis. J Immunol 2001; 166: 4319-4326.
    • (2001) J Immunol , vol.166 , pp. 4319-4326
    • Gillespie, R.D.1    Dolan, M.C.2    Piesman, J.3    Titus, R.G.4
  • 19
    • 0034705418 scopus 로고    scopus 로고
    • Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis
    • Valenzuela JG, Charlab R, Mather TN & Ribeiro JM. Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis. J Biol Chem 2000; 275: 18717-18723.
    • (2000) J Biol Chem , vol.275 , pp. 18717-18723
    • Valenzuela, J.G.1    Charlab, R.2    Mather, T.N.3    Ribeiro, J.M.4
  • 20
    • 0037155836 scopus 로고    scopus 로고
    • Characterization of a novel salivary immunosuppressive protein from Ixodes ricinus ticks
    • Leboulle G, Crippa M, Decrem Y et al. Characterization of a novel salivary immunosuppressive protein from Ixodes ricinus ticks. J Biol Chem 2002; 277: 10083-10089.
    • (2002) J Biol Chem , vol.277 , pp. 10083-10089
    • Leboulle, G.1    Crippa, M.2    Decrem, Y.3
  • 21
    • 0033029085 scopus 로고    scopus 로고
    • Salivary gland extract from Ixodes ricinus ticks inhibits production of interferon-gamma by the upregulation of interleukin-10
    • Kopecky J, Kuthejlova M, Pechova J, Lin JX & Leonard WJ. Salivary gland extract from Ixodes ricinus ticks inhibits production of interferon-gamma by the upregulation of interleukin-10. Parasite Immunol 1999; 21: 351-356.
    • (1999) Parasite Immunol , vol.21 , pp. 351-356
    • Kopecky, J.1    Kuthejlova, M.2    Pechova, J.3    Lin, J.X.4    Leonard, W.J.5
  • 22
    • 0035018568 scopus 로고    scopus 로고
    • Mechanisms of interleukin-10-mediated immune suppression
    • Akdis CA & Blaser K. Mechanisms of interleukin-10-mediated immune suppression. Immunology 2001; 103: 131-136.
    • (2001) Immunology , vol.103 , pp. 131-136
    • Akdis, C.A.1    Blaser, K.2
  • 23
    • 0030932709 scopus 로고    scopus 로고
    • Induction of apoptosis in human T-cells by organomercuric compounds: A flow cytometric analysis
    • Shenker BJ, Datar S, Mansfield K & Shapiro IM. Induction of apoptosis in human T-cells by organomercuric compounds: a flow cytometric analysis. Toxicol Appl Pharmacol 1997; 143: 397-406.
    • (1997) Toxicol Appl Pharmacol , vol.143 , pp. 397-406
    • Shenker, B.J.1    Datar, S.2    Mansfield, K.3    Shapiro, I.M.4
  • 24
    • 0035979435 scopus 로고    scopus 로고
    • Salivary gland extract of Rhipicephalus appendiculatus ticks inhibits in vitro transcription and production of cytokines and production of nitric oxide by LPS-stimulated JA-4 cells
    • Gwakisa P, Yoshihara K, Long To T, Gotoh H, Amano F & Momotani E. Salivary gland extract of Rhipicephalus appendiculatus ticks inhibits in vitro transcription and production of cytokines and production of nitric oxide by LPS-stimulated JA-4 cells. Vet Parasitol 2001; 99: 53-61.
    • (2001) Vet Parasitol , vol.99 , pp. 53-61
    • Gwakisa, P.1    Yoshihara, K.2    Long To, T.3    Gotoh, H.4    Amano, F.5    Momotani, E.6
  • 25
    • 0024671792 scopus 로고
    • Transmission of Theileria parva bovis (Boleni strain) to cattle resistant to the brown ear tick Rhipicephalus appendiculatus (Neumann)
    • Fivaz BH, Norval RA & Lawrence JA. Transmission of Theileria parva bovis (Boleni strain) to cattle resistant to the brown ear tick Rhipicephalus appendiculatus (Neumann). Trop Anim Health Prod 1989; 21: 129-134.
    • (1989) Trop Anim Health Prod , vol.21 , pp. 129-134
    • Fivaz, B.H.1    Norval, R.A.2    Lawrence, J.A.3
  • 26
    • 0035083540 scopus 로고    scopus 로고
    • Th2 polarization of the immune response of BALB/c mice to Ixodes ricinus instars, importance of several antigens in activation of specific Th2 sub-populations
    • Mejri N, Franscini N, Rutti B & Brossard M. Th2 polarization of the immune response of BALB/c mice to Ixodes ricinus instars, importance of several antigens in activation of specific Th2 sub-populations. Parasite Immunol 2001; 23: 61-69.
    • (2001) Parasite Immunol , vol.23 , pp. 61-69
    • Mejri, N.1    Franscini, N.2    Rutti, B.3    Brossard, M.4
  • 27
    • 0033982678 scopus 로고    scopus 로고
    • Cytokine responses of C3H/HeN mice infested with Ixodes scapularis or Ixodes pacificus nymphs
    • Schoeler GB, Manweiler SA & Wikel SK. Cytokine responses of C3H/HeN mice infested with Ixodes scapularis or Ixodes pacificus nymphs. Parasite Immunol 2000; 22: 31-40.
    • (2000) Parasite Immunol , vol.22 , pp. 31-40
    • Schoeler, G.B.1    Manweiler, S.A.2    Wikel, S.K.3
  • 28
    • 0031014147 scopus 로고    scopus 로고
    • Infestation with pathogen-free nymphs of the tick Ixodes scapularis induces host resistance to transmission of Borrelia burgdorferi by ticks
    • Wikel SK, Ramachandra RN, Bergman DK, Burkot TR & Piesman J. Infestation with pathogen-free nymphs of the tick Ixodes scapularis induces host resistance to transmission of Borrelia burgdorferi by ticks. Infect Immun 1997; 65: 335-338.
    • (1997) Infect Immun , vol.65 , pp. 335-338
    • Wikel, S.K.1    Ramachandra, R.N.2    Bergman, D.K.3    Burkot, T.R.4    Piesman, J.5
  • 29
    • 0032584515 scopus 로고    scopus 로고
    • Saliva of Rhipicephalus sanguineus tick impairs T cell proliferation and IFN-gamma-induced macrophage microbicidal activity
    • Ferreira BR & Silva JS. Saliva of Rhipicephalus sanguineus tick impairs T cell proliferation and IFN-gamma-induced macrophage microbicidal activity. Vet Immunol Immunopathol 1998; 64: 279-293.
    • (1998) Vet Immunol Immunopathol , vol.64 , pp. 279-293
    • Ferreira, B.R.1    Silva, J.S.2
  • 30
    • 0030057661 scopus 로고    scopus 로고
    • Immunosuppression and cytokine production in mice infected with Ixodes ricinus ticks: A possible role of laminine and interleukin-10 on the in vitro responsiveness of lymphocytes to mitogens
    • Ganapamo F, Rutti B & Brossard M. Immunosuppression and cytokine production in mice infected with Ixodes ricinus ticks: a possible role of laminine and interleukin-10 on the in vitro responsiveness of lymphocytes to mitogens. Immunology 1996; 87: 259-263.
    • (1996) Immunology , vol.87 , pp. 259-263
    • Ganapamo, F.1    Rutti, B.2    Brossard, M.3
  • 31
    • 0022047272 scopus 로고
    • Effects of tick infestation on the plaque-forming cell response to a thymic dependent antigen
    • Wikel SK. Effects of tick infestation on the plaque-forming cell response to a thymic dependent antigen. Ann Trop Med Parasitol 1985; 79: 195-198.
    • (1985) Ann Trop Med Parasitol , vol.79 , pp. 195-198
    • Wikel, S.K.1
  • 32
    • 0027327158 scopus 로고
    • Borrelia burgdorferi outer surface lipoproteins OspA and OspB possess B-cell mitogenic and cytokine-stimulatory properties
    • Ma Y & Weis JJ. Borrelia burgdorferi outer surface lipoproteins OspA and OspB possess B-cell mitogenic and cytokine-stimulatory properties. Infect Immun 1993; 61: 3843-3853.
    • (1993) Infect Immun , vol.61 , pp. 3843-3853
    • Ma, Y.1    Weis, J.J.2
  • 33
    • 0033850122 scopus 로고    scopus 로고
    • T-cell-independent responses to Borrelia burgdorferi are critical for protective immunity and resolution of Lyme disease
    • McKisic MD & Barthold SW. T-cell-independent responses to Borrelia burgdorferi are critical for protective immunity and resolution of Lyme disease. Infect Immun 2000; 68: 5190-5197.
    • (2000) Infect Immun , vol.68 , pp. 5190-5197
    • McKisic, M.D.1    Barthold, S.W.2
  • 34
    • 0030741166 scopus 로고    scopus 로고
    • Production of cytokines by human B cells in health and disease
    • Pistoia V. Production of cytokines by human B cells in health and disease. Immunol Today 1997; 18: 343-350.
    • (1997) Immunol Today , vol.18 , pp. 343-350
    • Pistoia, V.1
  • 35
    • 0035660755 scopus 로고    scopus 로고
    • CD19(+) cells produce IFN-gamma in mice infected with Borrelia burgdorferi
    • Ganapamo F, Dennis VA & Philipp MT. CD19(+) cells produce IFN-gamma in mice infected with Borrelia burgdorferi. Eur J Immunol 2001; 31: 3460-3468.
    • (2001) Eur J Immunol , vol.31 , pp. 3460-3468
    • Ganapamo, F.1    Dennis, V.A.2    Philipp, M.T.3
  • 36
    • 0344171995 scopus 로고    scopus 로고
    • Characterization of anergic anti-DNA B cells: B cell hyporesponsiveness is a T cell-independent and potentially reversible process
    • Noorchashm H, Bui A, Li HL et al. Characterization of anergic anti-DNA B cells: B cell hyporesponsiveness is a T cell-independent and potentially reversible process. Int Immunol 1999; 11: 765-776.
    • (1999) Int Immunol , vol.11 , pp. 765-776
    • Noorchashm, H.1    Bui, A.2    Li, H.L.3
  • 37
    • 0032572815 scopus 로고    scopus 로고
    • Pyrazole bioisosteres of leflunomide as B-cell immunomodulators for xenotransplantation and chronic rejection: Scope and limitations
    • Papageorgiou C, Albert R, Floersheim P et al. Pyrazole bioisosteres of leflunomide as B-cell immunomodulators for xenotransplantation and chronic rejection: scope and limitations. J Med Chem 1998; 41: 3530-3538.
    • (1998) J Med Chem , vol.41 , pp. 3530-3538
    • Papageorgiou, C.1    Albert, R.2    Floersheim, P.3


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