L-type calcium channels selectively control the defensive behaviors induced by electrical stimulation of dorsal periaqueductal gray and overlying collicular layers

Behavioural Brain Research

Volumn 111, Issue 1-2, 2000, Pages 175-185

  Schenberg, Luiz Carlos ^a   Pimentel De Almeida Marçal, Leonardo ^a   Seeberger, Fabiana ^a   Rufina De Barros, Maria ^a   Murari Sudré, Eliana Cristina ^a  

^a Department of Physiological Sciences   (Brazil)

Author keywords

Defence reaction; Defensive behavior; Flight behavior; Freezing behavior; L type calcium channel; Logistic threshold analysis; PAG; Periaqueductal gray

Indexed keywords

CALCIUM CHANNEL; COBALT CHLORIDE; VERAPAMIL;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DEFENSIVE BEHAVIOR; ELECTROSTIMULATION; MALE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT;

AGGRESSION; ANIMALS; AROUSAL; BRAIN MAPPING; CALCIUM CHANNELS; ELECTRIC STIMULATION; FEAR; MALE; MOTOR ACTIVITY; PERIAQUEDUCTAL GRAY; RATS; RATS, WISTAR; SUPERIOR COLLICULUS;

EID: 0034660107     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(00)00154-6     Document Type: Article

References (63)

1. Adams D.B., Baccelli G., Mancia G., Zanchetti A. Relation of cardiovascular changes in fighting to emotion and exercise. J. Physiol. (London). 212:1971;321-335.
2. Amano K., Tanikawa T., Iseki H., Kawabatake H., Notani M., Kawamura H., Kitamura K. Single neuron analysis of the human midbrain tegmentum (rostral mesencephalic reticulotomy for pain relief). Appl. Neurophysiol. 41:1978;66-78.
3. Bandler R., Carrive P. Integrated defense reaction elicited by excitatory aminoacid microinjection in the midbrain periaqueductal gray region of the unrestrained cat. Brain Res. 439:1988;95-106.
4. Bandler R., Depaulis A. Midbrain periaqueductal gray control of defensive behavior in the cat and the rat. Depaulis A., Bandler R. The Midbrain Periaqueductal Gray Matter. 1991;175-198 Plenum Press, New York.
5. Bandler R., Keay K. Columnar organization in the midbrain periaqueductal gray and the integration of emotional expression. Prog. Brain Res. 107:1998;285-300.
6. Bandler R., Carrive P., Depaulis A. Emerging principles of organization of the midbrain periaqueductal gray matter. Depaulis A., Bandler R. The Midbrain Periaqueductal Gray Matter. 1991;1-8 Plenum, New York.
7. Bertolino M., Llinás R. The central role of voltage-activated and receptor-operated calcium channels in neuronal cells. Annu. Rev. Pharmacol. Toxicol. 32:1992;399-421.
8. Bittencourt AS. Intrinsic properties of dorsolateral and lateral columns of the periaqueductal gray matter. M.Sc. thesis, Federal University of Espírito Santo, Vitória, 1999.
9. Blanchard R.J., Blanchard D.C. Attack and defense in rodents as ethoexperimental models for the study of emotions. Prog. Neuro-Psychopharmacol. Biol. Psychiat. 13:1989;S3-S14.
10. Blanchard R.J., Griebel G., Henrie J.A., Blanchard D.C. Differentiation of anxiolytic and panicolytic drugs by effects on rat and mouse defense test batteries. Neurosci. Biobehav. Rev. 21:1997;783-789.
11. Blok B.F., Holstege G. Direct projections from the periaqueductal gray to the pontine micturition center (M-region). An anterograde and retrograde tracing study in the cat. Neurosci. Lett. 166:1994;93-96.
12. Blok B.F., De Weerd H., Holstege G. Ultrastructural evidence for a paucity of projections from the lumbosacral cord to the pontine micturition center or M-region in the cat: a new concept for the organization of the micturition reflex with the periaqueductal gray as central relay. J. Comp. Neurol. 359:1995;300-309.
13. Boudin H., Pelaprat D., Rostene W., Beaudet A. Cellular distribution of neurotensisn receptors in rat brain: immunohistochemical study using an antipeptide antibody against the cloned high affinity receptor. J. Comp. Neurol. 373:1996;76-89.
14. 1A receptors on neurones of the rat midbrain tectum. Brain Res. 556:1991;259-266.
15. Carrive P. The periaqueductal gray and defensive behavior: functional representation and neuronal organization. Behav. Brain Res. 58:1993;27-47.
16. Carrive P. Functional organization of PAG neurons controlling regional vascular beds. Depaulis A., Bandler R. The Midbrain Periaqueductal Gray Matter. 1991;67-100 Plenum, New York.
17. Carrive P., Schmitt P., Karli P. Flight induced by microinjection of D-tubocurarine or a-bungarotoxin into medial hypothalamus or periaqueductal gray matter: cholinergic or GABAergic mediation? Behav. Brain Res. 2:1986;233-248.
18. Coimbra N.C., Eichenberger G.C., Gorchinski R.T., Maisonnette S. Effects of the blockade of opioid receptor on defensive reactions elicited by electrical stimulation within the deep layers of the superior colliculus and DPAG. Brain Res. 736:1996;348-352.
19. Collett D. Modelling Binary Data. 1991;Chapman and Hall, London.
20. Dean P., Mitchell I.J., Redgrave P. Response resembling defensive behavior produced by microinjection of glutamate into the superior colliculus of rats. Neuroscience. 24:1988;501-510.
21. Driver P.M., Humphreys D.A. Protean Behavior: The Biology of Unpredictability. 1988;Oxford University Press, New York.
22. Fedynyshyn J.P., Kwiat G., Lee N.M. Characterization of high affinity opioid biding sites in rat periaqueductal gray P2 membrane. J. Pharmacol. 159:1989;83-88.
23. Fernandez de Molina A., Hunsperger R.W. Organization of the subcortical system governing defense and flight reactions in the cat. J. Physiol. (London). 160:1962;200-213.
24. Graeff F.G. Role of 5-HT in defensive behavior and anxiety. Rev. Neurosci. 4:1993;181-211.
25. Graybiel A.M., Brecha N., Karten H.J. Cluster and sheet pattern of enkephalin like immunoreactivity in the superior colliculus of the cat. Neuroscience. 12:1984;191-214.
26. Graybiel A.M., Illing R.B. Enkephalin positive and acetylcholinesterase positive patch systems in the superior colliculus have matching distributions but distinct developmental histories. J. Comp. Neurol. 340:1994;297-310.
27. Griebel G., Blanchard D.C., Jung A., Lee J.C., . Masuda C.K., Blanchard R.J. Further evidence that the mouse defense test battery is useful for screening anxiolytic and panicolytic drugs: effects of acute and chronic treatment with alprazolam. Neuropharmacology. 34:1995;1625-1633.
28. Griebel G., Blanchard D.C., Agnes R.S., Blanchard R.J. Differential modulation of antipredator defensive behavior in Swiss-Webster mice following acute or chronic administration of imipramine and fluoxetine. Psychopharmacology (Berlin). 120:1995;57-66.
29. Guimarães F.S., Carobrez A.P., De Aguiar J.C., Graeff F.G. Anxiolytic effect on the elevated plus-maze of the NMDA receptor antagonist AP7 microinjected into the dorsal periaqueductal gray. Psychopharmacology (Berlin). 103:1990;91-94.
30. Hamalainen M.M., Lovick T.A. Role of nitric oxide and serotonin in modulation of the cardiovascular defense response evoked by stimulation in the periaqueductal gray matter in rats. Neurosci. Lett. 229:1997;105-108.
31. 2+ channels. Mol. Pharmacol. 50:1996;1284-1294.
32. Jenck F., Moreau J.L., Martin J.R. Dorsal periaqueductal gray-induced aversion as a simulation of panic anxiety: elements of face and predictive validity. Psychiatry Res. 57:1995;181-191.
33. 2+ channels in the rat periaqueductal gray neurons by mu-type opioid agonist. J. Neurophysiol. 77:1997;1418-1424.
34. Llinás R., Yarom Y. Electrophysiology of mammalian inferior olivary neurones in vitro. Different types of voltage dependent ionic conductances. J. Physiol. (London). 315:1981;549-567.
35. Lovick T.A. Serotonergic influence from nucleus raphe obscurus on neurones in the periaqueductal gray matter in the rat. Brain Res. 606:1993;92-98.
36. Lovick T.A., Key B.J. Inhibitory effect of nitric oxide on neuronal activity in the periaqueductal gray matter of the rat. Exp. Brain Res. 108:1996;382-388.
37. 1A receptors are involved in inhibition of the midbrain-evoked cardiovascular defense response by nucleus raphe obscurus. Br. J. Pharmacol. 117:1996;94P.
38. Marseillan R.F. A solid state sine-wave stimulator. Physiol. Behav. 19:1977;339-340.
39. Matheus M.G., Nogueira R.L., Carobrez A.P., Graeff F.G., Guimarães F.S. Anxiolytic effect of glycine antagonists microinjected into the dorsal periaqueductal gray. Psychopharmacology (Berlin). 113:1994;565-569.
40. Nashold B.S. Jr., Wilson W.P., Slaughter G. Sensations evoked by stimulation in the midbrain of man. J. Neurosurg. 30:1969;14-24.
41. Nashold B.S. Jr., Wilson W.P., Slaughter D.G. The midbrain and pain. Bonica J.J. International Symposium on Pain Advances in Neurology. 4:1974;191-196 Raven Press, New York.
42. Nogueira R.L., Graeff F.G. Role of 5-HT receptor subtypes in the modulation of dorsal periaqueductal gray generated aversion. Pharmacol. Biochem. Behav. 52:1995;1-6.
43. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 2nd ed. 1986;Academic Press, San Diego.
44. Redgrave P., Dean P. Does the PAG learn about emergencies from the superior colliculus? Depaulis A., Bandler R. The Midbrain Periaqueductal Gray Matter. 1991;199-209 Plenum, New York.
45. Reiman E.M., Raichle M.E., Robins E., Mintun M.A., Fusselman M.J., Fox P.T., Price J.L., Hackman K.A. Neuroanatomical correlates of a lactate-induced anxiety attack. Arch. Gen. Psychol. 46:1989;493-500.
46. Russo A.S., Guimarães F.S., De Aguiar J.C., Graeff F.G. Role of benzodiazepine receptors located in the dorsal periaqueductal gray in anxiety. Psychopharmacology (Berlin). 110:1992;198-202.
47. Sánchez D., Ribas J. Properties and ionic basis of the action potentials in the periaqueductal gray neurones of the guinea-pig. J. Physiol. (London). 440:1991;167-187.
48. Schenberg L.C., Aguiar J.C., Graeff F.G. Gaba modulation of the defense reaction induced by brain electrical stimulation. Physiol. Behav. 31:1983;429-437.
49. Schenberg L.C., Vasquez E.C., Costa M.B. Cardiac baroreflex dynamics during the defense reaction in freely moving rats. Brain Res. 621:1993;50-58.
50. Schenberg L.C., Vargas L.C., Medeiros R.L., Marques T.A., Silva S.R., Fraipont P., Tufik S. Evaluation of the rat defense reaction as a model of panic attack in man: pharmacological and neuroendocrine evidence. Int. J. Psychophys. 30:1998;127-128.
51. Schmitt M.L., Graeff F.G., Carobrez A.P. Anxiolytic effect of kynurenic acid microinjected into the dorsal periaqueductal gray matter of rats placed in the elevated plus-maze test. Braz. J. Med. Biol. Res. 23:1990;677-679.
52. Schmitt M.L., Coelho W., Lopes-de-Souza A.S., Guimarães F.S., Carobrez A.P. Anxiogenic-like effect of glycine and D-serine microinjected into dorsal periaqueductal gray matter of rats. Neurosci. Lett. 189:1995;93-96.
53. Smith G.S.T., Savery D., Marden C., Costa J.J.L., Averill S., Priestley J.V., Rattray M. Distribution of messenger RNAs encoding enkephalin, substance P, somatostatin, galanin, vasoactive intestinal polypeptide, neuropeptide Y, and calcitonin gene related peptide in the midbrain periaqueductal gray in the rat. J. Comp. Neurol. 373:1994;23-40.
54. Souza M.M., Schenberg L.C., Carobrez A.P. NMDA-coupled periaqueductal gray glycine receptors modulate anxioselective drug effects on plus-maze performance. Behav. Brain Res. 90:1998;157-165.
55. Steriade M., Llinás R. The functional states of the thalamus and the associated neuronal interplay. Physiol. Rev. 68:1988;649-742.
56. Sudré E.C.M., Barros M.R., Sudré G.N., Schenberg L.C. Thresholds of electrically induced defense reaction of the rat: short- and long-term adaptation mechanisms. Behav. Brain Res. 58:1993;141-154.
57. 2+ signalling: problems and pitfalls. TIPS. 19:1998;370-375.
58. Tishler M.D., Davis M. A visual pathway that mediates fear-conditioned enhancement of acoustic startle. Brain Res. 276:1983;55-71.
59. Vargas LC, Marques TA, Schenberg LC Micturition and defensive behaviors are controlled by distinct neural networks within the dorsal periaqueductal gray and deep gray layer of the superior colliculus of the rat. Neurosci. Lett. 280:2000;45-48.
60. Vaughan C.W., Christie M.J. Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal gray in vitro. J. Physiol. (London). 498:1997;463-472.
61. Vaughan C.W., Bandler R., Christie M.J. Differential responses of lateral and ventrolateral periaqueductal gray neurones to noradrenaline in vitro. J. Physiol. (London). 490:1996;373-381.
62. Young R.F. Brain and spinal stimulation: how and to whom! Clin. Neurosurg. 35:1989;429-447.
63. Zhang S.P., Bandler R., Carrive P. Flight and immobility evoked by excitatory amino acid microinjection within distinct parts of the subtentorial midbrain periaqueductal gray of the cat. Brain Res. 520:1990;73-82.