A novel class of peptide found in scorpion venom with neurodepressant effects in peripheral and central nervous system of the rat

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1649, Issue 1, 2003, Pages 58-67

  Corona, Miguel ^a   Coronas, Fredy V ^a   Merino, Enrique ^a   Becerril, Baltazar ^a   Gutiérrez, Rafael ^b   Rebolledo Antunez, Santiago ^c   Garcia, David E ^c   Possani, Lourival D ^a  

^a INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Amino acid sequence; Centruroides limpidus; Epilepsy; Gene cloning; Na+ channel; Neurodepression; Neuron; Scorpion toxin

Indexed keywords

ANTICONVULSIVE AGENT; SODIUM CHANNEL; VENOM; CLL9 TOXIN, CENTRUROIDES LIMPIDUS; NEUROTOXIN; PEPTIDE; SCORPION VENOM; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DNA DETERMINATION; GENE SEQUENCE; INTRON; MOLECULAR CLONING; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SCORPION; SIGNAL TRANSDUCTION; SLEEP; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; DRUG SCREENING; GANGLION; GENETICS; GRYLLIDAE; ISOLATION AND PURIFICATION; MALE; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY; WISTAR RAT;

CENTRUROIDES; CENTRUROIDES LIMPIDUS; CENTRUROIDES LIMPIDUS LIMPIDUS; CRUSTACEA; HEXAPODA; SCORPIONES;

AMINO ACID SEQUENCE; ANIMALS; ANTICONVULSANTS; BASE SEQUENCE; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CLONING, MOLECULAR; DRUG EVALUATION, PRECLINICAL; GANGLIA; GRYLLIDAE; INTRONS; MALE; MICE; MOLECULAR SEQUENCE DATA; NEUROTOXINS; PEPTIDES; PERIPHERAL NERVOUS SYSTEM; RATS; RATS, WISTAR; SCORPION VENOMS; SEQUENCE HOMOLOGY, AMINO ACID; SLEEP; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 0041620461     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-9639(03)00155-9     Document Type: Article

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