Pd(en) as a sequence-selective molecular pinch for α-helical peptides

Chemistry Letters

Volumn , Issue 1, 2001, Pages 16-17

  Hamachi, Itaru ^a,b   Kasagi, Noriyuki ^a   Kiyonaka, Shigeki ^a   Nagase, Tsuyoshi ^a   Mito Oka, Yasuko ^a   Shinkai, Seiji ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b INSTITUTE FOR MOLECULAR SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035530825     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.2001.16     Document Type: Article

References (17)

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13. Details were previously described. I. Hamachi, Y. Yamada, T. Matsugi, and S. Shinkai, Chem. Eur. J., 5, 1503 (1999).
14. The parentheses [ ] indicate the helix content in the absence of Pd(en). The helix contents are calculated according to the following paper: P. C. Lyu, L. A. Marky, N. R. Kallenbach, J. Am. Chem. Soc., 111, 2733 (1989).
15. The distances were estimated assuming that the conformation of the peptides is the typical α-helix in the region of the corresponding His residues.
16. Kostic and co-workers reported that the excess amount of Pd(en) can cleave a peptide bond of some His-appended peptides at higher temperature, a) T. N. Parac and N. M. Kostic, J. Am. Chem. Soc., 118, 5946 (1996).
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