메뉴 건너뛰기




Volumn 731, Issue 1-2, 1996, Pages 141-154

Ultrastructural localization of μ-opioid receptors in the superficial layers of the rat cervical spinal cord: Extrasynaptic localization and proximity to Leu5-enkephalin

Author keywords

Afferent; Analgesia; Anatomy; Neurotransmitter; Ultrastructure

Indexed keywords

LEUCINE ENKEPHALIN; MU OPIATE RECEPTOR;

EID: 0030603111     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00492-1     Document Type: Article
Times cited : (60)

References (73)
  • 1
    • 0026575450 scopus 로고
    • C-terminal tail of β-adrenergic receptors; immunocytochemical localization within astrocytes and their relation to catecholaminergic neurons in n. Tractus solitarii and area postrema
    • [1] Aoki, C. and Pickel, V.M., C-terminal tail of β-adrenergic receptors; immunocytochemical localization within astrocytes and their relation to catecholaminergic neurons in n. tractus solitarii and area postrema, Brain Res., 571 (1992) 35-49.
    • (1992) Brain Res. , vol.571 , pp. 35-49
    • Aoki, C.1    Pickel, V.M.2
  • 2
    • 0019860088 scopus 로고
    • Ultrastructural localization and biochemical features of immunoreactive leuenkephalin in monkey dorsal horn
    • [2] Aronin, N., Di Figlia, M., Liotta, A.S. and Martin, J.B., Ultrastructural localization and biochemical features of immunoreactive leuenkephalin in monkey dorsal horn, J. Neurosci., 1 (1981) 561-577.
    • (1981) J. Neurosci. , vol.1 , pp. 561-577
    • Aronin, N.1    Di Figlia, M.2    Liotta, A.S.3    Martin, J.B.4
  • 4
    • 0017694439 scopus 로고
    • Autoradiographic localization of opiate receptors in rat brain. III. The telencephalon
    • [4] Atweh, S.F. and Kuhar, M.J., Autoradiographic localization of opiate receptors in rat brain. III. The telencephalon, Brain Res., 134 (1977) 393-405.
    • (1977) Brain Res. , vol.134 , pp. 393-405
    • Atweh, S.F.1    Kuhar, M.J.2
  • 5
    • 0021288912 scopus 로고
    • Endogenous pain control systems: Brainstem spinal pathways and endorphin circuitry
    • [5] Basbaum, A.I. and Fields, H.L., Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry, Annu. Rev. Neurosci., 7 (1984) 309-338.
    • (1984) Annu. Rev. Neurosci. , vol.7 , pp. 309-338
    • Basbaum, A.I.1    Fields, H.L.2
  • 6
    • 0017797287 scopus 로고
    • Differential excitatory and inhibitory effects of opiates on non-nociceptive and nociceptive neurones in the spinal cord of the cat
    • [6] Belcher, G. and Ryall, R.W., Differential excitatory and inhibitory effects of opiates on non-nociceptive and nociceptive neurones in the spinal cord of the cat. Brain Res., 145 (1978) 303-314.
    • (1978) Brain Res. , vol.145 , pp. 303-314
    • Belcher, G.1    Ryall, R.W.2
  • 7
    • 0017262602 scopus 로고
    • Analgesia induced in vivo by central administration of enkephalin in rat
    • [7] Belluzzi, J.D., Grant, N., Garsky, V., Sarantakis, D., Wise, C.D. and Stein, L.. Analgesia induced in vivo by central administration of enkephalin in rat. Nature, 260 (1976) 625-626.
    • (1976) Nature , vol.260 , pp. 625-626
    • Belluzzi, J.D.1    Grant, N.2    Garsky, V.3    Sarantakis, D.4    Wise, C.D.5    Stein, L.6
  • 8
    • 0025307494 scopus 로고
    • Pre-and postsynaptic distribution of μ, δ and κ opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord
    • [8] Besse, D., Lombard, M.C., Zajac, J.M., Roques, B.P. and Besson, J.M., Pre-and postsynaptic distribution of μ, δ and κ opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord, Brain Res., 521 (1990) 15-22.
    • (1990) Brain Res. , vol.521 , pp. 15-22
    • Besse, D.1    Lombard, M.C.2    Zajac, J.M.3    Roques, B.P.4    Besson, J.M.5
  • 9
    • 0023754944 scopus 로고
    • The physiological basis of pain pathways and the segmental controls of pain
    • [9] Besson, J.M., The physiological basis of pain pathways and the segmental controls of pain. Acta Anaesthesiol. Belg., 39 (1988) 47-51.
    • (1988) Acta Anaesthesiol. Belg. , vol.39 , pp. 47-51
    • Besson, J.M.1
  • 10
    • 0019852797 scopus 로고
    • Immunoreactive dynorphin in mammalian spinal cord and dorsal root ganglia
    • [10] Botticelli, L.J., Cox, B.M. and Goldstein, A., Immunoreactive dynorphin in mammalian spinal cord and dorsal root ganglia. Proc. Natl. Acad. Sci. USA. 78 (1981) 7783-7786.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 7783-7786
    • Botticelli, L.J.1    Cox, B.M.2    Goldstein, A.3
  • 13
    • 0025100314 scopus 로고
    • Optimisation of differential immunogold-silver and peroxidase labeling with maintenance of ultrastructure in brain sections before plastic embedding
    • [13] Chan, J., Aoki, C. and Pickel, V.M., Optimisation of differential immunogold-silver and peroxidase labeling with maintenance of ultrastructure in brain sections before plastic embedding. J. Neurosci. Methods. 33 (1990) 113-127.
    • (1990) J. Neurosci. Methods. , vol.33 , pp. 113-127
    • Chan, J.1    Aoki, C.2    Pickel, V.M.3
  • 15
    • 0000870839 scopus 로고
    • Ultrastructural localization of μ-opioid receptor immunoreactivity and relationship to enkephalin in cervical dorsal horn of the rat spinal cord
    • [15] Cheng, P.Y., Moriwaki, A., Wang, J.B., Uhl, G.R. and Pickel, V.M., Ultrastructural localization of μ-opioid receptor immunoreactivity and relationship to enkephalin in cervical dorsal horn of the rat spinal cord. Analgesia. 1 (1995) 363-366.
    • (1995) Analgesia. , vol.1 , pp. 363-366
    • Cheng, P.Y.1    Moriwaki, A.2    Wang, J.B.3    Uhl, G.R.4    Pickel, V.M.5
  • 16
    • 0029027070 scopus 로고
    • Ultrastructural immunolabeling shows prominent presynaptic vesicular localization of δ-opioid receptor within both enkephalin and non-enkephalin containing axon terminals in the superficial layers of the rat cervical spinal cord
    • [16] Cheng, P.Y., Svingos, A.L., Wang, H.W., Clarke, C.L., Jenab, S., Beczkowska, I.W., Inturrisi, C.E. and Pickel, V.M., Ultrastructural immunolabeling shows prominent presynaptic vesicular localization of δ-opioid receptor within both enkephalin and non-enkephalin containing axon terminals in the superficial layers of the rat cervical spinal cord. J. Neurosci., 15 (1995) 5976-5988.
    • (1995) J. Neurosci. , vol.15 , pp. 5976-5988
    • Cheng, P.Y.1    Svingos, A.L.2    Wang, H.W.3    Clarke, C.L.4    Jenab, S.5    Beczkowska, I.W.6    Inturrisi, C.E.7    Pickel, V.M.8
  • 17
    • 0023522750 scopus 로고
    • Autoradiographic evidence of serotonin 1 binding sites on primary afferent fibres in the dorsal horn of the rat spinal cord
    • [17] Daval, G., Verge, D., Basbaum, A.I., Bourgoin, S. and Hamon, M., Autoradiographic evidence of serotonin 1 binding sites on primary afferent fibres in the dorsal horn of the rat spinal cord. Neurosci. Lett., 83 (1987) 71-76.
    • (1987) Neurosci. Lett. , vol.83 , pp. 71-76
    • Daval, G.1    Verge, D.2    Basbaum, A.I.3    Bourgoin, S.4    Hamon, M.5
  • 18
    • 0023265850 scopus 로고
    • Opioid receptor subtypes in the rat spinal cord: Electrophysiological studies with μ-and δ-opioid receptor agonists in the control of nociception
    • [18] Dickenson, A.H., Sullivan, A.F., Knox, R., Zajac, J.M. and Roques, B.P., Opioid receptor subtypes in the rat spinal cord: electrophysiological studies with μ-and δ-opioid receptor agonists in the control of nociception. Brain Res., 413 (1987) 36-44.
    • (1987) Brain Res. , vol.413 , pp. 36-44
    • Dickenson, A.H.1    Sullivan, A.F.2    Knox, R.3    Zajac, J.M.4    Roques, B.P.5
  • 19
    • 0028980794 scopus 로고
    • Co-localization of μ-opioid receptor-like and substance P-like immunoreactivities in axon terminals within the superficial layers of the medullary and spinal dorsal horns of the rat
    • [19] Ding, Y.Q., Nomura, S., Kaneko, T. and Mizuno, N., Co-localization of μ-opioid receptor-like and substance P-like immunoreactivities in axon terminals within the superficial layers of the medullary and spinal dorsal horns of the rat. Neurosci. Lett., 198 (1995) 45-48.
    • (1995) Neurosci. Lett. , vol.198 , pp. 45-48
    • Ding, Y.Q.1    Nomura, S.2    Kaneko, T.3    Mizuno, N.4
  • 20
    • 0020666481 scopus 로고
    • Electrophysiology of opioid peptides and sensory systems
    • [20] Duggan, A.W., Electrophysiology of opioid peptides and sensory systems. Br. Med. Bull., 39 (1983) 65-70.
    • (1983) Br. Med. Bull. , vol.39 , pp. 65-70
    • Duggan, A.W.1
  • 21
    • 0017689294 scopus 로고
    • Suppression of transmission of nociceptive impulses by morphine: Selective effects of morphine administered in the region of the substantia gelatinosa
    • [21] Duggan, A.W., Hall, J.G. and Headley, P.M., Suppression of transmission of nociceptive impulses by morphine: selective effects of morphine administered in the region of the substantia gelatinosa, Brain Res., 61 (1977) 65-76.
    • (1977) Brain Res. , vol.61 , pp. 65-76
    • Duggan, A.W.1    Hall, J.G.2    Headley, P.M.3
  • 22
    • 0017196892 scopus 로고
    • Immunohistochemical studies using antibodies to leucine-enkephalin: Initial observations on the nervous system of the rat
    • [22] Elde, R., Hokfelt, T., Johansson, O. and Terenius, L., Immunohistochemical studies using antibodies to leucine-enkephalin: initial observations on the nervous system of the rat. Neuroscience. 1 (1976) 340-351.
    • (1976) Neuroscience , vol.1 , pp. 340-351
    • Elde, R.1    Hokfelt, T.2    Johansson, O.3    Terenius, L.4
  • 23
    • 0023110291 scopus 로고
    • 3H]diprenorphine binding sites with the laminar pattern of substance P. myelin and Nissl staining
    • 3H]diprenorphine binding sites with the laminar pattern of substance P. myelin and Nissl staining, Neuroscience, 20 (1987) 395-407.
    • (1987) Neuroscience , vol.20 , pp. 395-407
    • Faull, R.L.1    Villiger, J.W.2
  • 24
    • 0019482353 scopus 로고
    • The immunocytochemical localization of enkephalin in the central nervous system of the rat
    • [24] Finley, J.C., Maderdrut, J.L. and Petrusz, P., The immunocytochemical localization of enkephalin in the central nervous system of the rat. J. Comp. Neurol., 198 (1981) 541-565.
    • (1981) J. Comp. Neurol. , vol.198 , pp. 541-565
    • Finley, J.C.1    Maderdrut, J.L.2    Petrusz, P.3
  • 25
    • 0028169755 scopus 로고
    • 2-. And μ-opioid receptor agonists on excitatory transmission in lamina II neurons of adult rat spinal cord
    • 2-. and μ-opioid receptor agonists on excitatory transmission in lamina II neurons of adult rat spinal cord, J. Neurosci., 14 (1994) 4965-4971.
    • (1994) J. Neurosci. , vol.14 , pp. 4965-4971
    • Glaum, S.R.1    Miller, R.J.2    Hammond, D.L.3
  • 26
    • 0023280702 scopus 로고
    • Release of substance P from the cat spinal cord
    • [26] Go, V.L. and Yaksh, T.L., Release of substance P from the cat spinal cord, J. Physiol,. 391 (1987) 141-167.
    • (1987) J. Physiol,. , vol.391 , pp. 141-167
    • Go, V.L.1    Yaksh, T.L.2
  • 27
    • 0000745561 scopus 로고
    • Differentiation of δ and μ opiate receptor localizations by light microscopic autoradiography
    • [27] Goodman, R.R., Snyder, S.H., Kuhar, M.J. and Young III, W.S., Differentiation of δ and μ opiate receptor localizations by light microscopic autoradiography. Proc. Natl. Acad. Sci. USA, 11 (1980) 6239-6243.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.11 , pp. 6239-6243
    • Goodman, R.R.1    Snyder, S.H.2    Kuhar, M.J.3    Young W.S. III4
  • 28
    • 0028385286 scopus 로고
    • μ,-opioid agonists inhibit spinal trigeminal substantia gelatinosa neurons in guinea pig and rat
    • [28] Grudt, T.J. and Williams, J.T., μ,-Opioid agonists inhibit spinal trigeminal substantia gelatinosa neurons in guinea pig and rat, J. Neurosci., 14 (1994) 1646-1654.
    • (1994) J. Neurosci. , vol.14 , pp. 1646-1654
    • Grudt, T.J.1    Williams, J.T.2
  • 29
    • 0021171468 scopus 로고
    • Electron microscopic autoradiographic localization of opioid receptors in rat neostriatum
    • [29] Hamel, E. and Beaudet, A., Electron microscopic autoradiographic localization of opioid receptors in rat neostriatum, Nature, 312 (1984) 155-157.
    • (1984) Nature , vol.312 , pp. 155-157
    • Hamel, E.1    Beaudet, A.2
  • 30
    • 0023634852 scopus 로고
    • Mismatches between neurotransmitter and receptor localizations in brain: Observations and implications
    • [30] Herkenham, M., Mismatches between neurotransmitter and receptor localizations in brain: observations and implications, Neuroscience, 23 (1987) 1-38.
    • (1987) Neuroscience , vol.23 , pp. 1-38
    • Herkenham, M.1
  • 32
    • 0018971348 scopus 로고
    • The electron microscopic localization of methionine-enkephalin within the superficial layers (I and II) of the spinal cord
    • [32] Hunt, S.P., Kelly, J.S. and Emson, P.C., The electron microscopic localization of Methionine-enkephalin within the superficial layers (I and II) of the spinal cord. Neuroscience, 5 (1980) 1871-1890.
    • (1980) Neuroscience , vol.5 , pp. 1871-1890
    • Hunt, S.P.1    Kelly, J.S.2    Emson, P.C.3
  • 33
    • 0027048462 scopus 로고
    • Spinal antinociceptive effects of [D-Ala2]deltorphin II. A novel and highly selective δ-opioid receptor agonist
    • [33] Improta, G. and Broccardo, M., Spinal antinociceptive effects of [D-Ala2]deltorphin II. a novel and highly selective δ-opioid receptor agonist. Peptides, 13 (1992) 1123-1126.
    • (1992) Peptides , vol.13 , pp. 1123-1126
    • Improta, G.1    Broccardo, M.2
  • 34
    • 0023767103 scopus 로고
    • Enkephalins modulate excitatory synaptic transmission in the superficial dorsal horn by acting at μ-opioid receptor sites
    • [34] Jeftinija, S., Enkephalins modulate excitatory synaptic transmission in the superficial dorsal horn by acting at μ-opioid receptor sites, Brain Res., 460 (1988) 260-268.
    • (1988) Brain Res. , vol.460 , pp. 260-268
    • Jeftinija, S.1
  • 35
    • 0018392311 scopus 로고
    • Substance p: Depletion in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neurons
    • [35] Jessell, T., Tsunoo, A., Kanazawa, I. and Otsuka, M., Substance P: depletion in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neurons, Brain Res., 168 (1979) 247-259.
    • (1979) Brain Res. , vol.168 , pp. 247-259
    • Jessell, T.1    Tsunoo, A.2    Kanazawa, I.3    Otsuka, M.4
  • 36
    • 0017622848 scopus 로고
    • Opiate analgesics inhibit substance P release from rat trigeminal nucleus
    • [36] Jessell, T.M. and Iversen, L.L.. Opiate analgesics inhibit substance P release from rat trigeminal nucleus. Nature. 268 (1977) 549-551.
    • (1977) Nature , vol.268 , pp. 549-551
    • Jessell, T.M.1    Iversen, L.L.2
  • 37
    • 0017074204 scopus 로고
    • Opiate receptor binding in primate spinal cord: Distribution and changes after dorsal root section
    • [37] Lamotte, C., Pert, C.B. and Snyder, S.H.. Opiate receptor binding in primate spinal cord: distribution and changes after dorsal root section. Brain Res., 112 (1976) 407-412.
    • (1976) Brain Res. , vol.112 , pp. 407-412
    • Lamotte, C.1    Pert, C.B.2    Snyder, S.H.3
  • 38
    • 0019486524 scopus 로고
    • A novel immunocytochemical model system for specificity and sensitivity screening of antisera against multiple antigens
    • [38] Larsson, L.I.. A novel immunocytochemical model system for specificity and sensitivity screening of antisera against multiple antigens, J. Histochem. Cytochem., 29 (1981) 408-410.
    • (1981) J. Histochem. Cytochem. , vol.29 , pp. 408-410
    • Larsson, L.I.1
  • 39
    • 0000354303 scopus 로고
    • Electron microscopic pre-embedding double immunostaining methods
    • L. Heimer and L. Zaborszky (Eds.), Plenum, New York
    • [39] Leranth, C. and Pickel, V.M., Electron microscopic pre-embedding double immunostaining methods. In L. Heimer and L. Zaborszky (Eds.), Neuroanatomical Tract-tracing Methods II, Recent Progress, Plenum, New York, 1989, pp. 129-172.
    • (1989) Neuroanatomical Tract-tracing Methods II, Recent Progress , pp. 129-172
    • Leranth, C.1    Pickel, V.M.2
  • 40
    • 0018758817 scopus 로고
    • Reexamination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers
    • [40] Light, A.R. and Perl, E.R., Reexamination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers, J. Comp. Neurol., 186 (1979) 117-131.
    • (1979) J. Comp. Neurol. , vol.186 , pp. 117-131
    • Light, A.R.1    Perl, E.R.2
  • 41
    • 0028091385 scopus 로고
    • Synaptic relationship between substance P and the substance p receptor: Light and electron microscopic characterization of the mismatch between neuropeptides and their receptors
    • [41] Liu, H., Brown, J.L., Jasmin, L., Maggio, J.E., Vigna, S.R., Mantyh, P.W. and Basbaum, A.I., Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors. Proc. Natl. Acad. Sci. USA, 91 (1994) 1009-1013.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1009-1013
    • Liu, H.1    Brown, J.L.2    Jasmin, L.3    Maggio, J.E.4    Vigna, S.R.5    Mantyh, P.W.6    Basbaum, A.I.7
  • 42
    • 0018130198 scopus 로고
    • Specific-opiate-induced depression of transmitter release from dorsal root ganglion cells in culture
    • [42] Macdonald, R.L. and Nelson, P.G.. Specific-opiate-induced depression of transmitter release from dorsal root ganglion cells in culture, Science, 199 (1978) 1449-1451.
    • (1978) Science , vol.199 , pp. 1449-1451
    • Macdonald, R.L.1    Nelson, P.G.2
  • 43
    • 0022611336 scopus 로고
    • Immunocytochemical localization of proenkephalin-derived peptides in the central nervous system of the rat
    • [43] Merchenthaler, I., Maderdrut, J.L., Altschuler, R.A. and Petrusz, P., Immunocytochemical localization of proenkephalin-derived peptides in the central nervous system of the rat. Neuroscience, 17 (1986) 325-348.
    • (1986) Neuroscience , vol.17 , pp. 325-348
    • Merchenthaler, I.1    Maderdrut, J.L.2    Altschuler, R.A.3    Petrusz, P.4
  • 44
    • 0023107697 scopus 로고
    • Comparison of Met-enkephalin-, dynorphin A-. And neurotensin-immunoreactive neurons in the cat and rat spinal cords: I. Lumbar cord
    • [44] Miller, K.E. and Seybold, V.S., Comparison of Met-enkephalin-, dynorphin A-. and neurotensin-immunoreactive neurons in the cat and rat spinal cords: I. Lumbar cord, J. Comp. Neurol., 255 (1987) 293-304.
    • (1987) J. Comp. Neurol. , vol.255 , pp. 293-304
    • Miller, K.E.1    Seybold, V.S.2
  • 45
    • 0024394479 scopus 로고
    • Ultrastructural basis for interactions between central opioids and catecholamines. I. Rostral ventrolateral medulla
    • [45] Milner, T.A., Pickel, V.M. and Reis, D.J., Ultrastructural basis for interactions between central opioids and catecholamines. I. Rostral ventrolateral medulla, J. Neurosci., 9 (1989) 2114-2130.
    • (1989) J. Neurosci. , vol.9 , pp. 2114-2130
    • Milner, T.A.1    Pickel, V.M.2    Reis, D.J.3
  • 46
    • 0026075628 scopus 로고
    • Axon collaterals indicate broad intraspinal role for sacral preganglionic neurons
    • [46] Morgan, C.W., de Groat. W.C., Felkins, L.A. and Zhang, S.J., Axon collaterals indicate broad intraspinal role for sacral preganglionic neurons. Proc. Natl. Acad. Sci. USA, 88 (1991) 6888-6892.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6888-6892
    • Morgan, C.W.1    De Groat, W.C.2    Felkins, L.A.3    Zhang, S.J.4
  • 47
    • 0019971149 scopus 로고
    • Localization of opiate and histamine H1-receptors in the primate sensory ganglia and spinal cord
    • [47] Ninkovic, M., Hunt, S.P. and Gleave, J.R., Localization of opiate and histamine H1-receptors in the primate sensory ganglia and spinal cord. Brain Res., 241 (1982) 197-206.
    • (1982) Brain Res. , vol.241 , pp. 197-206
    • Ninkovic, M.1    Hunt, S.P.2    Gleave, J.R.3
  • 48
    • 0019825389 scopus 로고
    • Effect of dorsal rhizotomy on the autoradiographic distribution of opiate and neurotensin receptors and neurotensin-like immunoreactivity within the rat spinal cord
    • [48] Ninkovic, M., Hunt, S.P. and Kelly. J.S.. Effect of dorsal rhizotomy on the autoradiographic distribution of opiate and neurotensin receptors and neurotensin-like immunoreactivity within the rat spinal cord. Brain Res., 230 (1981) 111-119.
    • (1981) Brain Res. , vol.230 , pp. 111-119
    • Ninkovic, M.1    Hunt, S.P.2    Kelly, J.S.3
  • 51
    • 52649114611 scopus 로고
    • The use of lead citrate at high ph as an electronopaque stain in electron microscopy
    • [51] Reynolds, E.S.. The use of lead citrate at high pH as an electronopaque stain in electron microscopy. J. Cell Biol., 17 (1963) 208
    • (1963) J. Cell Biol. , vol.17 , pp. 208
    • Reynolds, E.S.1
  • 53
    • 0020049940 scopus 로고
    • Opiates and pain pathways: Demonstration of enkephalin synapses on dorsal horn projection neurons
    • [53] Ruda, M.A., Opiates and pain pathways: demonstration of enkephalin synapses on dorsal horn projection neurons. Science, 215 (1982) 1523-1525.
    • (1982) Science , vol.215 , pp. 1523-1525
    • Ruda, M.A.1
  • 54
    • 0021635407 scopus 로고
    • Demonstration of post-synaptic opioid modulation of thalamic projection neurons by the combined techniques of retrograde horseradish peroxidase and enkephalin immuncytochemistry
    • [54] Ruda, M.A., Coffield, J. and Dubner, R.. Demonstration of post-synaptic opioid modulation of thalamic projection neurons by the combined techniques of retrograde horseradish peroxidase and enkephalin immuncytochemistry, J. Neurosci., 4 (1984) 2117-2132.
    • (1984) J. Neurosci. , vol.4 , pp. 2117-2132
    • Ruda, M.A.1    Coffield, J.2    Dubner, R.3
  • 55
    • 0024411803 scopus 로고
    • Ontogeny of μ, and δ opioid receptors and of neutral endopeptidase in human spinal cord: An autoradiographic study
    • [55] Sales, N., Charnay, Y., Zajac, J.M., Dubois, P.M. and Roques, B.P., Ontogeny of μ, and δ opioid receptors and of neutral endopeptidase in human spinal cord: an autoradiographic study. J. Chem. Neuroanat., 2 (1989) 179-188.
    • (1989) J. Chem. Neuroanat. , vol.2 , pp. 179-188
    • Sales, N.1    Charnay, Y.2    Zajac, J.M.3    Dubois, P.M.4    Roques, B.P.5
  • 56
    • 0018123998 scopus 로고
    • Immunohistochemical localization of enkephalin in rat brain and spinal cord
    • [56] Sar, M., Stumpf, W.E., Miller, R.J., Chang, K.J. and Cuatrecasas, P., Immunohistochemical localization of enkephalin in rat brain and spinal cord, J. Comp. Neurol., 182 (1978) 17-37.
    • (1978) J. Comp. Neurol. , vol.182 , pp. 17-37
    • Sar, M.1    Stumpf, W.E.2    Miller, R.J.3    Chang, K.J.4    Cuatrecasas, P.5
  • 57
    • 0021360975 scopus 로고
    • In vivo studies on spinal opiate receptor systems mediating antinociception. II. Pharmacological profiles suggesting a differential association of μ, δ and κ receptors with visceral chemical and cutaneous thermal stimuli in the rat
    • [57] Schmauss, C. and Yaksh, T.L., In vivo studies on spinal opiate receptor systems mediating antinociception. II. Pharmacological profiles suggesting a differential association of μ, δ and κ receptors with visceral chemical and cutaneous thermal stimuli in the rat. J. Pharmacol. Exp. Ther., 228 (1984) 1-12.
    • (1984) J. Pharmacol. Exp. Ther. , vol.228 , pp. 1-12
    • Schmauss, C.1    Yaksh, T.L.2
  • 58
    • 0025853840 scopus 로고
    • Biochemical characterization and regional quantification of μ, δ and κ opioid binding sites in rat spinal cord
    • [58] Stevens, C.W., Lacey, C.B., Miller, K.E., Elde, R.P. and Seybold, V.S., Biochemical characterization and regional quantification of μ, δ and κ opioid binding sites in rat spinal cord. Brain Res., 550 (1991) 77-85.
    • (1991) Brain Res. , vol.550 , pp. 77-85
    • Stevens, C.W.1    Lacey, C.B.2    Miller, K.E.3    Elde, R.P.4    Seybold, V.S.5
  • 59
    • 0022527022 scopus 로고
    • Spinal action of dermorphin, an extremely potent peptide from frog skin
    • [59] Stevens, C.W. and Yaksh, T.L., Spinal action of dermorphin, an extremely potent peptide from frog skin, Brain Res., 385 (1986) 300-304.
    • (1986) Brain Res. , vol.385 , pp. 300-304
    • Stevens, C.W.1    Yaksh, T.L.2
  • 60
    • 0027240819 scopus 로고
    • Opioid actions on neurons of rat lateral amygdala in vitro
    • [60] Sugita, S. and North, R.A., Opioid actions on neurons of rat lateral amygdala in vitro, Brain Res., 612 (1993) 151-155.
    • (1993) Brain Res. , vol.612 , pp. 151-155
    • Sugita, S.1    North, R.A.2
  • 61
    • 0022981156 scopus 로고
    • Central projections of identified, unmyelinated (c) afferent fibers innervating mammalian skin
    • [61] Sugiura, Y., Lee, C.L. and Perl, E.R., Central projections of identified, unmyelinated (c) afferent fibers innervating mammalian skin, Science, 234 (1986) 358-361.
    • (1986) Science , vol.234 , pp. 358-361
    • Sugiura, Y.1    Lee, C.L.2    Perl, E.R.3
  • 62
    • 0028170438 scopus 로고
    • μ opiate receptor: Charged transmembrane domain amino acids are critical for agonist recognition and intrinsic activity
    • [62] Surratt, C.K., Johnson, P.S., Moriwaki, A., Seidleck, B.K., Blaschak, C.J., Wang, J.B. and Uhl, G.R., μ Opiate receptor: charged transmembrane domain amino acids are critical for agonist recognition and intrinsic activity, J. Biol. Chem., 32 (1994) 20548-20553.
    • (1994) J. Biol. Chem. , vol.32 , pp. 20548-20553
    • Surratt, C.K.1    Johnson, P.S.2    Moriwaki, A.3    Seidleck, B.K.4    Blaschak, C.J.5    Wang, J.B.6    Uhl, G.R.7
  • 63
    • 0027156901 scopus 로고
    • 2+ currents in bovine adrenal chromaffin cells
    • 2+ currents in bovine adrenal chromaffin cells, Neuron, 10 (1993) 701-709.
    • (1993) Neuron , vol.10 , pp. 701-709
    • Twitchell, W.A.1    Rane, S.G.2
  • 64
    • 0022483544 scopus 로고
    • Autoradiographic comparison of the distribution of the neutral endopeptidase 'enkephalinase' and of μ and δ opioid receptors in rat brain
    • [64] Waksman, G., Hamel, E., Fournie-Zaluski, M.C. and Roques, B.P., Autoradiographic comparison of the distribution of the neutral endopeptidase 'enkephalinase' and of μ and δ opioid receptors in rat brain, Proc. Natl. Acad. Sci. USA, 83 (1986) 1523-1527.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 1523-1527
    • Waksman, G.1    Hamel, E.2    Fournie-Zaluski, M.C.3    Roques, B.P.4
  • 65
    • 0020084417 scopus 로고
    • Distribution of opiate receptors in the monkey brain: An autoradiographic study
    • [65] Wamsley, J.K., Zarbin, M.A., Young III, W.S. and Kuhar, M.J., Distribution of opiate receptors in the monkey brain: an autoradiographic study, Neuroscience, 1 (1982) 595-613.
    • (1982) Neuroscience , vol.1 , pp. 595-613
    • Wamsley, J.K.1    Zarbin, M.A.2    Young W.S. III3    Kuhar, M.J.4
  • 67
    • 0027967989 scopus 로고
    • Activation of μ-opioid receptor modulates GABAa receptor-mediated currents in isolated spinal dorsal horn neurons
    • [67] Wang, R.A. and Randic, M., Activation of μ-opioid receptor modulates GABAa receptor-mediated currents in isolated spinal dorsal horn neurons. Neurosci. Lett., 180 (1994) 109-113.
    • (1994) Neurosci. Lett. , vol.180 , pp. 109-113
    • Wang, R.A.1    Randic, M.2
  • 68
    • 0021288283 scopus 로고
    • Effects of iontophoretically released peptides on primate spinothalamic tract cells
    • [68] Willcockson, W.S., Chung, J.M., Hori, Y., Lee, K.H. and Willis, W.D.. Effects of iontophoretically released peptides on primate spinothalamic tract cells, J. Neurosci., 4 (1984) 741-750.
    • (1984) J. Neurosci. , vol.4 , pp. 741-750
    • Willcockson, W.S.1    Chung, J.M.2    Hori, Y.3    Lee, K.H.4    Willis, W.D.5
  • 69
    • 0019947923 scopus 로고
    • Enkephalin opens potassium channels on mammalian central neurones
    • [69] Williams, J.T., Egan, T.M. and North, R.A., Enkephalin opens potassium channels on mammalian central neurones, Nature, 299 (1982) 74-77.
    • (1982) Nature , vol.299 , pp. 74-77
    • Williams, J.T.1    Egan, T.M.2    North, R.A.3
  • 70
    • 0020599793 scopus 로고
    • Substantia gelatinosa neurones hyperpolarized in vitro by enkephalin
    • [70] Yoshimura, M. and North, R.A.. Substantia gelatinosa neurones hyperpolarized in vitro by enkephalin, Nature, 305 (1983) 529-530.
    • (1983) Nature , vol.305 , pp. 529-530
    • Yoshimura, M.1    North, R.A.2
  • 71
    • 0024494028 scopus 로고
    • Autoradiographic study of μ and δ opioid binding sites and neutral endopeptidase-24.11 in rat after dorsal root rhizotomy
    • [71] Zajac, J.M., Lombard, M.C., Peschanski, M., Besson, J.M. and Roques, B.P., Autoradiographic study of μ and δ opioid binding sites and neutral endopeptidase-24.11 in rat after dorsal root rhizotomy, Brain Res., 477 (1989) 400-403.
    • (1989) Brain Res. , vol.477 , pp. 400-403
    • Zajac, J.M.1    Lombard, M.C.2    Peschanski, M.3    Besson, J.M.4    Roques, B.P.5
  • 72
    • 0028170280 scopus 로고
    • Ultrastructural study of δ-opioid receptors in the dorsal horn of the rat spinal cord using monoclonal anti-idiotypic antibodies
    • [72] Zerari, F., Zouaoui, D., Gastard, M., Apartis, E., Fischer, J., Herbrrecht, F., Cupo, A., Cucumel, K. and Conrath, M.. Ultrastructural study of δ-opioid receptors in the dorsal horn of the rat spinal cord using monoclonal anti-idiotypic antibodies, J. Chem. Neuroanat., 7 (1994) 159-170.
    • (1994) J. Chem. Neuroanat. , vol.7 , pp. 159-170
    • Zerari, F.1    Zouaoui, D.2    Gastard, M.3    Apartis, E.4    Fischer, J.5    Herbrrecht, F.6    Cupo, A.7    Cucumel, K.8    Conrath, M.9
  • 73
    • 0018378548 scopus 로고
    • The effects of methionine-and leucine-enkephalin on spinal neurones of the cat
    • [73] Zieglgansberger, W. and Tulloch, I.F., The effects of methionine-and leucine-enkephalin on spinal neurones of the cat, Brain Res., 167 (1979) 53-64.
    • (1979) Brain Res. , vol.167 , pp. 53-64
    • Zieglgansberger, W.1    Tulloch, I.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.