Structural and biochemical characterization of a new Mg2+ binding site near Tyr94 in the restriction endonuclease PvuII

Journal of Molecular Biology

Volumn 331, Issue 2, 2003, Pages 395-406

  Spyridaki, Aspasia ^a   Matzen, Claudia ^b   Lanio, Thomas ^b   Jeltsch, Albert ^b   Simoncsits, Andras ^c   Athanasiadis, Alekos ^a,d   Scheuring Vanamee, Eva ^a   Kokkinidis, Michael ^a   Pingoud, Alfred ^b  

^a INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Crystallography; DNA cleavage; Kinetics; Mechanism of catalysis; Metal ion binding

Indexed keywords

ASPARAGINE; DNA; ENDONUCLEASE; GLUTAMIC ACID; MAGNESIUM ION; PHENYLALANINE; PROTEIN SUBUNIT; TYROSINE;

ARTICLE; BINDING SITE; BIOCHEMISTRY; CATALYSIS; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CRYSTAL STRUCTURE; DNA CLEAVAGE; DNA STRAND; HILL REACTION; PRIORITY JOURNAL; RESTRICTION SITE; WILD TYPE;

EID: 0041347883     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(03)00692-2     Document Type: Article

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