Short-term exposure to 17α-ethynylestradiol decreases the fertility of sexually maturing male rainbow trout (Oncorhynchus mykiss)

Environmental Toxicology and Chemistry

Volumn 22, Issue 6, 2003, Pages 1272-1280

  Schultz, Irvin R ^a   Skillman, Ann ^a   Nicolas, Jean Marc ^b   Cyr, Daniel G ^b   Nagler, James J ^c  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^b INRS INSTITUT ARMAND FRAPPIER   (Canada)

^c UNIVERSITY OF IDAHO   (United States)

Author keywords

Embryonic development; Endocrine disruption; Environmental estrogens; Sperm motility

Indexed keywords

ALCOHOLS; BIOCHEMISTRY; EFFLUENTS; HISTOLOGY; HORMONES; TOXICITY;

FERTILIZATION;

WATER ANALYSIS;

11 OXOTESTOSTERONE; 17,20BETA DIHYDROXYPREGN 4 EN 3 ONE; ETHINYLESTRADIOL; WATER;

CHEMICAL POLLUTANT; EMBRYONIC DEVELOPMENT; ESTROGENIC COMPOUND; REPRODUCTION; SALMONID; SEWAGE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DOSE TIME EFFECT RELATION; ENVIRONMENTAL EXPOSURE; ESTROGEN ACTIVITY; GONAD DEVELOPMENT; GONADOSOMATIC INDEX; HEPATOSOMATIC INDEX; HISTOPATHOLOGY; HORMONE ACTION; INCUBATION TIME; MALE; MALE FERTILITY; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAINBOW TROUT; REPRODUCTION; SEWAGE EFFLUENT; SEXUAL MATURATION; SPERM; SPERMATOCRIT; SPERMATOZOON DENSITY; SPERMATOZOON MOTILITY; STEROID ANALYSIS; TESTIS CELL;

ANIMALS; ENVIRONMENTAL EXPOSURE; ETHINYL ESTRADIOL; FEMALE; FERTILIZATION; FISH DISEASES; HYDROXYPROGESTERONES; INFERTILITY; MALE; SEMEN; SEXUAL MATURATION; SPERMATOGENESIS; TESTIS; TESTOSTERONE; TIME FACTORS; TROUT; WATER POLLUTANTS, CHEMICAL;

ANIMALIA; ONCORHYNCHUS; ONCORHYNCHUS MYKISS; SALMONIDAE;

EID: 0041315719     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/1551-5028(2003)022<1272:STETED>2.0.CO;2     Document Type: Article

References (43)

1. Jobling S, Nolan M, Tyler CR, Brighty G, Sumpter JP. 1998. Widespread sexual disruption in wild fish. Environ Sci Technol 32:2498-2506.
2. Loomis AK, Thomas P. 1999. Binding characteristics of estrogen receptor (ER) in Atlantic croaker (Micropogonias undulatus) testis: Different affinity for estrogens and xenobiotics from that of hepatic ER. Biol Reprod 61:51-60.
3. Fent K. 2001. Fish cell lines as versatile tools in ecotoxicology: Assessment of cytotoxicity, cytochrome P4501A induction potential and estrogenic activity of chemicals and environmental samples. Toxicol In Vitro 15:477-488.
4. Kloas W, Schrag B, Ehnes C, Segner H. 2000. Binding of xenobiotics to hepatic estrogen receptor and plasma sex steroid binding protein in the teleost fish, the common carp (Cyprinus carpio). Gen Comp Endocrinol 119:287-299.
5. Arcand-Hoy LD, Benson WH. 1998. Fish reproduction: An ecologically relevant indicator of endocrine disruption. Environ Toxicol Chem 17:49-57.
6. Larsson DGJ, Adolfsson-Erici M, Parkkonen J, Pettersson M, Berg AH, Olsson PE, Forlin L. 1999. Ethinyloestradiol - An undesired fish contraceptive? Aquat Toxicol 45:91-97.
7. Desbrow C, Routledge EJ, Brighty GC, Sumpter JP, Waldock M. 1998. Identification of estrogenic chemicals in STW effluent. 1. Chemical fractionation and in vitro biological screening. Environ Sci Technol 32:1549-1558.
8. Snyder SA, Keith TL, Verbrugge DA, Snyder EM, Gross TS, Kannan K, Giesy JP. 1999. Analytical methods for detection of selected estrogenic compounds in aqueous mixtures. Environ Sci Technol 33:2814-2820.
9. Ternes TA, Stumpf M, Mueller J, Haberer K, Wilken RD, Servos M. 1999. Behavior and occurrence of estrogens in municipal sewage treatment plants - I. Investigations in Germany, Canada and Brazil. Sci Total Environ 225:81-90.
10. Baronti C, Curini R, D'Ascenzo G, Di Corcia A, Gentili A, Samperi R. 2000. Monitoring natural and synthetic estrogens at activated sludge sewage treatment plants and in a receiving river water. Environ Sci Technol 34:5059-5066.
11. Huang CH, Sedlak DL. 2001. Analysis of estrogenic hormones in municipal wastewater effluent and surface water using enzyme-linked immunosorbent assay and gas chromatography/tandem mass spectrometry. Environ Toxicol Chem 20:133-139.
12. Kolpin DW, Furlong ET, Meyer MT, Thurman EM, Zaugg SD, Barber LB, Buxton HT. 2002. Pharmaceuticals, hormones, and other organic wastewater contaminants in US streams, 1999-2000: A national reconnaissance. Environ Sci Technol 36:1202-1211.
13. Sheahan DA, Bucke D, Matthiessen P, Sumpter JP, Kirby MF, Neall P, Waldock M. 1994. The effects of low levels of 17alpha-ethylnylestradiol upon plasma vitellogenin levels in male and female rainbow trout, Oncorhynchus mykiss. In Muller R, Lloyd R, eds, Sublethal and Chronic Effects of Pollutants on Freshwater Fish. Blackwell, Oxford, UK, pp 99-112.
14. Zillioux EJ, Johnson I, Kiparissis Y, Metcalfe CD, Wheat JV, Ward SG. Liu H. 2001. The sheepshead minnow as an in vivo model for endocrine disruption in marine teleosts: A partial life-cycle test with 17-ethynylestradiol. Environ Toxicol Chem 20: 1968-1978.
15. Scholz S, Gutzeit HO. 2000. 17-alpha-ethinylestradiol affects reproduction, sexual differentiation and aromatase gene expression of the medaka (Oryzias latipes). Aquat Toxicol 50:363-373.
16. Lange R, Hutchinson TH, Croudace CP, Siegmund F. 2001. Effects of the synthetic estrogen 17 alpha-ethinylestradiol on the life-cycle of the fathead minnow (Pimephales promelas). Environ Toxicol Chem 20:1216-1227.
17. Piferrer F, Donaldson EM. 1989. Gonadal differentiation in coho salmon, Oncorhynchus-kisutch, after a single treatment with androgen or estrogen at different stages during ontogenesis. Aquaculture 77:251-262.
18. Vizziano D, LeGac F, Fostier A. 1996. Effect of 17 beta-estradiol, testosterone, and 11-ketotestosterone on 17,20 beta-dihydroxy-4-pregnen-3-one production in the rainbow trout testis. Gen Comp Endocrinol 104:179-188.
19. Legler J, Broekhof Jose LM, Brouwer A, Lanser PH, Murk AJ, van der Saag PT, Vethaak AD, Wester P, Zivkovic D, van der BB. 2000. A novel in vivo bioassay for (xeno-) estrogens using transgenic zebrafish. Environ Sci Technol 34:4439-4444.
20. Schultz IR, Orner G, Merdink JL, Skillman A. 2001. Dose-response relationships and pharmacokinetics of vitellogenin in rainbow trout after intravascular administration of 17 alpha-ethynyl-estradiol. Aquat Toxicol 51:305-318.
21. Scott AP, Bye VJ, Baynes SM, Springate JRC. 1980. Seasonal-variations in plasma-concentrations of 11-ketotestosterone and testosterone in male rainbow trout, Salmo gairdneri richardson. J Fish Biol 17:495-505.
22. Shioda T, Wakabayashi M. 2000. Evaluation of reproductivity of medaka (Oryzias latipes) exposed to chemicals using a 2-week reproduction test. Water Sci Technol 42:53-60.
23. Van den Belt K, Verheyen R, Witters H. 2001. Reproductive effects of ethynylestradiol and 4t-octylphenol on the zebrafish (Danio rerio). Arch Environ Contam Toxicol 41:458-467.
24. Kime DE, Nash JP. 1999. Gamete viability as an indicator of reproductive endocrine disruption in fish. Sci Total Environ 233: 123-129.
25. Piironen J, Hyvarinen H. 1983. Composition of the milt of some teleost fishes. J Fish Biol 22:351-361.
26. Munkittrick KR, Moccia RD. 1987. Seasonal-changes in the quality of rainbow-trout (Salmo gairdneri) semen - Effect of a delay in stripping on spermatocrit, motility, volume and seminal plasma constituents. Aquaculture 64:147-156.
27. Ciereszko A, Dabrowski K. 1993. Estimation of sperm concentration of rainbow trout, whitefish and yellow perch using a spectrophotometric technique. Aquaculture 109:367-373.
28. Geffen AJ, Evans JP. 2000. Sperm traits and fertilization success of male and sex-reversed female rainbow trout (Oncorhynchus mykiss). Aquaculture 182:61-72.
29. Koldras M, Loir M, Maisse G, LeGac F. 1996. Study of the composition of seminal fluid and of sperm motility along the genital tract, during a spawning season, in the rainbow trout (Oncorhynchus mykiss). Aquat Living Resour 9:337-345.
30. Billard R. 1988. Artificial-insemination and gamete management in fish. Mar Behav Physiol 14:3-21.
31. Scott AP, Baynes SM. 1980. A review of the biology, handling and storage of salmonid spermatozoa. J Fish Biol 17:707-739.
32. Lahnsteiner F, Berger B, Weismann T, Patzner R. 1996. Changes in morphology, physiology, metabolism, and fertilization capacity of rainbow trout semen following cryopreservation. Prog Fish-Cult 58:149-159.
33. Rurangwa E, Roelants I, Huyskens G, Ebrahimi M, Kime DE, Ollevier F. 1998. The minimum effective spermatozoa:egg ratio for artificial insemination and the effects of mercury on sperm motility and fertilization ability in Clarias gariepinus. J Fish Biol 53:402-413.
34. Lahnsteiner F, Berger B, Weismann T, Patzner RA. 1998. Determination of semen quality of the rainbow trout, Oncorhynchus mykiss, by sperm motility, seminal plasma parameters, and spermatozoal metabolism. Aquaculture 163:163-181.
35. Fostier A, Billard R, Breton B, Legendre M, Marlot S. 1982. Plasma 11-oxotestosterone and gonadotropin during the beginning of spermiation in rainbow trout (Salmo gairdneri). Gen Comp Endocrinol 46:428-434.
36. Schulz R. 1984. Serum levels of 11-oxotestosterone in male and 17-beta- estradiol in female rainbow-trout (Salmo gairdneri) during the 1st reproductive-cycle. Gen Comp Endocrinol 56:111-120.
37. Miura T, Yamauchi K, Takahashi H, Nagahama Y. 1992. The role of hormones in the acquisition of sperm motility in salmonid fish. J Exp Zool 261:359-363.
38. Amer MA, Miura T, Miura C, Yamauchi K. 2001. Involvement of sex steroid hormones in the early stages of spermatogenesis in Japanese huchen (Hucho perryi). Biol Reprod 65:1057-1066.
39. Vizziano D, Fostier A, Le Gac F, Loir M. 1996. 20b-hydroxysteroid dehydrogenase activity in nonflagellated germ cells of rainbow trout testis. Biol Reprod 54:1-7.
40. Bouma J, Nagler JJ. 2001. Estrogen receptor-a protein localization in the testis of the rainbow trout (Oncorhynchus mykiss) during different stages of the reproductive cycle. Biol Reprod 65:60-65.
41. Le Gac F, Loir M. 1988. Control of testis function in fish: In vitro studies of gonadotropic regulation in the trout (Salmo gairdneri). Reprod Nutr Dev 28:1031-1046.
42. U.S. Geological Survey. 1997. Reconnaissance of 17 beta-Estradiol, 11-Ketotestostorone, Vitellogenin, and Gonad Histopathology in Common Carp of the United States Streams: Potential for Contaminant-Induced Endocrine Disruption. Open file report 96-627. Sacramento, CA.
43. Ankley GT, Jensen KM, Kahl MD, Korte JJ, Makynen EA. 2001. Description and evaluation of a short-term reproduction test with the fathead minnow (Pimephales promelas). Environ Toxicol Chem 20:1276-1290.