Tumor suppressor INK4: Quantitative structure-function analyses of p18(INK4C) as an inhibitor of cyclin-dependent kinase 4

Biochemistry

Volumn 39, Issue 4, 2000, Pages 649-657

  Li, Junan ^a   Poi, Ming Jye ^a   Qin, Dongyan ^a   Selby, Thomas L ^a   Byeon, In Ja ^a   Tsai, Ming Daw ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; CYCLIN D2; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; MUTANT PROTEIN; PROTEIN P16; TUMOR SUPPRESSOR INK4; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; ENZYME INHIBITION; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TERTIARY STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; CARRIER PROTEINS; CELL CYCLE PROTEINS; CRYSTALLOGRAPHY, X-RAY; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P18; CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; GENES, TUMOR SUPPRESSOR; HELIX-TURN-HELIX MOTIFS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR SUPPRESSOR PROTEINS;

EID: 0039596684     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991281u     Document Type: Article

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