IMCR V: The seven-component reaction

Acta Chemica Scandinavica

Volumn 52, Issue 1, 1998, Pages 107-113

  Dömling, Alexander ^a   Herdtweck, Eberhardt ^a   Ugi, Ivar ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0039352277     PISSN: 0904213X     EISSN: None     Source Type: Journal    
DOI: 10.3891/acta.chem.scand.52-0107     Document Type: Article

References (36)

1. Previous communication MCR III: Chattopadhyaya, J., Dömling, A., Lorentz, K., Richter, W., Ugi, I. and Werner, B. Nucleosides Nucleotides (1997). In press.
2. Ugi, I., Dömling, A. and Hörl, W. Endeavour 18 (1994) 115-122.
3. Strecker, A. Ann. Chem. 75 (1850) 27.
4. Hellmann, H. and Opitz, G. α-Aminoalkylierung, Verlag Chemie, Weinheim 1960.
5. Ugi, I. Isonitrile Chemistry, Academic Press, New York 1971.
6. Weber, L., Wallbaum, S., Broger, S. and Gubernator, Angew. Chem., Int. Ed. Engl. 34 (1995) 2280; Keating, T. A. and Armstrong, R. W. J. Org. Chem. 61 (1996) 8935; Short, K. M., Ching, B. W. and Mjalli, A. M. M. Tetrahedron Lett. 37 (1996) 7489; Park, W. K. C., Auer, M., Jaksche, H. and Wong, C.-H. J. Am. Chem. Soc. 118 (1996) 10150; Dömling, A., Richter, W. and Ugi, I. Nucleosides Nucleotides (1997). In press.
7. Weber, L., Wallbaum, S., Broger, S. and Gubernator, Angew. Chem., Int. Ed. Engl. 34 (1995) 2280; Keating, T. A. and Armstrong, R. W. J. Org. Chem. 61 (1996) 8935; Short, K. M., Ching, B. W. and Mjalli, A. M. M. Tetrahedron Lett. 37 (1996) 7489; Park, W. K. C., Auer, M., Jaksche, H. and Wong, C.-H. J. Am. Chem. Soc. 118 (1996) 10150; Dömling, A., Richter, W. and Ugi, I. Nucleosides Nucleotides (1997). In press.
8. Weber, L., Wallbaum, S., Broger, S. and Gubernator, Angew. Chem., Int. Ed. Engl. 34 (1995) 2280; Keating, T. A. and Armstrong, R. W. J. Org. Chem. 61 (1996) 8935; Short, K. M., Ching, B. W. and Mjalli, A. M. M. Tetrahedron Lett. 37 (1996) 7489; Park, W. K. C., Auer, M., Jaksche, H. and Wong, C.-H. J. Am. Chem. Soc. 118 (1996) 10150; Dömling, A., Richter, W. and Ugi, I. Nucleosides Nucleotides (1997). In press.
9. Weber, L., Wallbaum, S., Broger, S. and Gubernator, Angew. Chem., Int. Ed. Engl. 34 (1995) 2280; Keating, T. A. and Armstrong, R. W. J. Org. Chem. 61 (1996) 8935; Short, K. M., Ching, B. W. and Mjalli, A. M. M. Tetrahedron Lett. 37 (1996) 7489; Park, W. K. C., Auer, M., Jaksche, H. and Wong, C.-H. J. Am. Chem. Soc. 118 (1996) 10150; Dömling, A., Richter, W. and Ugi, I. Nucleosides Nucleotides (1997). In press.
10. Weber, L., Wallbaum, S., Broger, S. and Gubernator, Angew. Chem., Int. Ed. Engl. 34 (1995) 2280; Keating, T. A. and Armstrong, R. W. J. Org. Chem. 61 (1996) 8935; Short, K. M., Ching, B. W. and Mjalli, A. M. M. Tetrahedron Lett. 37 (1996) 7489; Park, W. K. C., Auer, M., Jaksche, H. and Wong, C.-H. J. Am. Chem. Soc. 118 (1996) 10150; Dömling, A., Richter, W. and Ugi, I. Nucleosides Nucleotides (1997). In press.
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12. One of us as early as 1961 mentioned the possibility of generating thousands of compounds in a combinatorial fashion, long before anyone thought about combinatorial chemistry: Ugi, I. and Steinbrückner, C. Chem. Ber. 94 (1961) 734; see also Früchtel, J. S. and Jung, G. Angew. Chem., Int. Ed. Engl. 35 (1996) 17. Balkenhohl, F., von dem Bussche-Hünnefeld, C., Lanky, A. and Zechel, C. Angew. Chem., Int. Ed. Engl. 35 (1996) 2288.
13. One of us as early as 1961 mentioned the possibility of generating thousands of compounds in a combinatorial fashion, long before anyone thought about combinatorial chemistry: Ugi, I. and Steinbrückner, C. Chem. Ber. 94 (1961) 734; see also Früchtel, J. S. and Jung, G. Angew. Chem., Int. Ed. Engl. 35 (1996) 17. Balkenhohl, F., von dem Bussche-Hünnefeld, C., Lanky, A. and Zechel, C. Angew. Chem., Int. Ed. Engl. 35 (1996) 2288.
14. One of us as early as 1961 mentioned the possibility of generating thousands of compounds in a combinatorial fashion, long before anyone thought about combinatorial chemistry: Ugi, I. and Steinbrückner, C. Chem. Ber. 94 (1961) 734; see also Früchtel, J. S. and Jung, G. Angew. Chem., Int. Ed. Engl. 35 (1996) 17. Balkenhohl, F., von dem Bussche-Hünnefeld, C., Lanky, A. and Zechel, C. Angew. Chem., Int. Ed. Engl. 35 (1996) 2288.
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17. Several other acid components suitable for iscyanide-driven MCRs have been identified recently: Dömling, A. Unpublished results.
18. Dömling, A. and Ugi, I. Angew. Chem., Int. Ed. Engl. 32 (1993) 563.
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32. Altomare, A., Cascarano, G., Giacovazzo, C., Guagliardi, A., Burla, M. C., Polidori, G. and Camalli, M. SIR-92, University Bari, Italy 1992; Sheldrick, G. M. SHELXL-93. A Program for the Solution of Crystal Structures from Diffraction Data; Acta Crystallogr., Sect. A 46 (1990) 467; Artus, G., Scherer, W., Priermeier, T. and Herdtweck, E. STRUX-V, A Program System to Handle X-ray Data, TU München, Germany 1994; Sheldrick, G. M. SHELXS-86, A Program for the Solution of Crystal Structures from Diffraction Data: Acta Crystallogr., Sect. A 46 (1990) 467; Frenz, B. A. SDP-Plus; Structure Determination Package, Version 4.0. Enraf-Nonius, Delft, The Netherlands 1988.
33. Altomare, A., Cascarano, G., Giacovazzo, C., Guagliardi, A., Burla, M. C., Polidori, G. and Camalli, M. SIR-92, University Bari, Italy 1992; Sheldrick, G. M. SHELXL-93. A Program for the Solution of Crystal Structures from Diffraction Data; Acta Crystallogr., Sect. A 46 (1990) 467; Artus, G., Scherer, W., Priermeier, T. and Herdtweck, E. STRUX-V, A Program System to Handle X-ray Data, TU München, Germany 1994; Sheldrick, G. M. SHELXS-86, A Program for the Solution of Crystal Structures from Diffraction Data: Acta Crystallogr., Sect. A 46 (1990) 467; Frenz, B. A. SDP-Plus; Structure Determination Package, Version 4.0. Enraf-Nonius, Delft, The Netherlands 1988.
34. Altomare, A., Cascarano, G., Giacovazzo, C., Guagliardi, A., Burla, M. C., Polidori, G. and Camalli, M. SIR-92, University Bari, Italy 1992; Sheldrick, G. M. SHELXL-93. A Program for the Solution of Crystal Structures from Diffraction Data; Acta Crystallogr., Sect. A 46 (1990) 467; Artus, G., Scherer, W., Priermeier, T. and Herdtweck, E. STRUX-V, A Program System to Handle X-ray Data, TU München, Germany 1994; Sheldrick, G. M. SHELXS-86, A Program for the Solution of Crystal Structures from Diffraction Data: Acta Crystallogr., Sect. A 46 (1990) 467; Frenz, B. A. SDP-Plus; Structure Determination Package, Version 4.0. Enraf-Nonius, Delft, The Netherlands 1988.
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