Immortalization of normal human embryonic fibroblasts by introduction of either the human papillomavirus type 16 E6 or E7 gene alone

International Journal of Cancer

Volumn 106, Issue 3, 2003, Pages 301-309

  Yamamoto, Akito ^a   Kumakura, Shin Ichi ^a   Uchida, Minoru ^a   Barrett, J Carl ^b,c   Tsutsui, Takeki ^a  

^a NIPPON DENTAL UNIVERSITY   (Japan)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

HPV 16 E6 or E7; Human fibroblasts; Immortalization; Immotalization

Indexed keywords

GENE PRODUCT; INK4A PROTEIN; PROTEIN E6; PROTEIN E7; RETINOBLASTOMA PROTEIN; RETROVIRUS VECTOR; TELOMERASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G1 PHASE; CELL IMMORTALIZATION; CELL POPULATION; CLONE; CONTROLLED STUDY; DNA DAMAGE; E6 GENE; E7 GENE; EMBRYO; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; NONHUMAN; PAPILLOMA VIRUS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TELOMERE; VIRUS ONCOGENE; X IRRADIATION;

BLOTTING, WESTERN; BROMODEOXYURIDINE; CELL CYCLE; CELL DIVISION; CELL TRANSFORMATION, VIRAL; CELLS, CULTURED; CPG ISLANDS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLINS; DNA; EMBRYO; FIBROBLASTS; GENES, P16; GENES, VIRAL; HUMANS; METHYLATION; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; RETINOBLASTOMA PROTEIN; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0038826812     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.11219     Document Type: Article

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