Ketogenic diet as an alternative therapy for children with refractory epilepsy: About 29 children;Le régime cétogène à visée anti-épileptique: Son utilisation chez 29 enfants épileptiques

Archives de Pediatrie

Volumn 10, Issue 4, 2003, Pages 300-306

  Francois, L Lion ^a   Manel, V ^a   Rousselle, C ^a   David, M ^a  

^a CENTRE HOSPITALIER LYON SUD   (France)

Author keywords

Child; Diet therapy; Epilepsy; Ketone bodies; Metabolism

Indexed keywords

ANTICONVULSIVE AGENT; KETONE BODY;

ARTICLE; CHILD; CLINICAL ARTICLE; DIET THERAPY; EPILEPSY; FEMALE; HEART DISEASE; HUMAN; HYPOKALEMIA; INFANT; KETOGENIC DIET; MALE; METABOLISM; PATIENT COMPLIANCE; SEIZURE; SIDE EFFECT;

EID: 0038790230     PISSN: 0929693X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0929-693X(03)00030-7     Document Type: Article

References (43)

1. Prasad AN, Stafstrom CF, Holmes GL. Alternative epilepsy therapies: the ketogenic diet, immunoglobulins and steroids. Epilepsia 1996;37 (Suppl 1):85-91.
2. Wilder RM. The effects of ketonemia on the course of epilepsy. Mayo Clin Proc 1921;2:307-8.
3. Lefevre F, Aronson N. Ketogenic diet for the treatment of refractory epilepsy in children: a systematic review of efficacity. Pediatrics 2000;105. URL: http://www.pediatrics.org/cgi/content/full/105/4/e46.
4. Freeman JM, Kelly MT, Freeman JB. The epilepsy diet treatment: An introduction to the ketogenic diet. New York: Demos Publications; 1996.
5. [51 Kinsman SL, Vining EP, Quaskey SA, Mellite D, Freeman JM. Efficacity of the ketogenic diet for intractable seizure disorders: review of 58 cases. Epilepsia 1992;33:1132-6.
6. Swoboda KJ, Specht L, Jones HR, Shapiro F, DiMauro S, Korson M. Infantile phosphofructo-kinase deficiency with arthrogryposis: clinical benefit of a ketogenic diet. J Pediatr 1997;131:932-4.
7. Wexler ID, Hemalatha SG, McConnell J, Buist NR, Dahl HH, Berry SA, et al. Outcome of pyruvate deshydrogenase deficiency treated with ketogenic diet, Studies in patients with identical mutations. Neurology 1997;49:1955-61.
8. Casey JC, Mc Grogan J, Pillas D, Pyzik P, Freeman J, Vining EP. The implementation and maintenance of the ketogenic diet in children. J Neurosci Nurs 1999;31:294-302.
9. Yao SG, Bough KJ, Eagles DA. Determination of the role of ketogenic ratio in preventing seizures in rats. Epilepsia 1998;39(Suppl 6):46.
10. Lustig S, Niesen CE. β-hydroxybutyrate suppresses pentylenetetrazol induced seizures in young adult rats. Epilepsia 1998;39(Suppl 6):36.
11. Freeman JM, Vining EP, Pyzik P, Gilbert DL. β-hydroxybutyrate levels in blood correlate with seizure controle in children on the ketogenic diet. Epilepsia 1998;39(Suppl 6):167.
12. Brown L, Lutchka LM, Bergquist C, Koo McCoy S, Stanley C, Chee C. Monitoring β-hydroxybutyrate as an anticonvulsivant level in the ketogenic diet. Epilepsia 1998;39(Suppl 6):168.
13. Bough KJ, Valiyil R, Han FT, Eagles DA. Seizure resistance is dependant upon age and caloric restriction in rats fed a ketogenic diet. Epilepsy Res 1999;35:21-8.
14. Persson B, Settergren G, Dahlquist G. Cerebral arterio-venous difference of aceto-acetate and beta-OH butyrate in children. Acta Paediatr Scand 1972;61:273-8.
15. Haymond MW, Howard C, Ben-Galim E, De Vivo DC. Effects of ketosis on glucose flux in children and adults. Am J Physiol 1983;245: 373-8.
16. Matthews PJ, Bough KJ, Eagles DA. A ketogenic diet markedly exacerbates seizure severity but elevates seizure threshold in the same animal [abstract]. Epilepsia 1998;39(Suppl 6):45.
17. Wheless JW. The ketogenic diet: Fa(c)t or fiction [editorial]. J Child Neurol 1995;10:419-23.
18. Freeman JM, Vining EP, Pillas DJ, Pyzik PL, Casey JC, Kelly LM. The efficacity of the ketogenic diet-1998: a prospective evaluation of intervention in 150 children. Pediatrics 1998;102:1358-63.
19. Berman W. Medium chain triglyceride diet in the treatment of intractable childhood epilepsy. Dev Med Child Neurol 1978;20:249-52.
20. Trauner DA. Medium chain triglycerid diet in intractable seizure disorders. Neurology 1985;35:237-8.
21. Vining EP, Freeman JM, Ballaban-Gil K, Camfield CS, Camfield PR, Holmes GL, et al. A multicenter study of the efficacity of the ketogenic diet. Arch Neurol 1998;55:1433-7.
22. Huttenlocher PR. Ketonemia and seizures: metabolic and anticonvulsivant effects of 2 ketogenic diet in epilepsy. Pediatr Res 1976;10: 536-40.
23. Swink T, Vining EP, Kelly MC. Efficacity of the classical ketogenic diet in children under 2 years of age [abstract]. Ann Neurol 1997;38 (Suppl 26).
24. Livingston S. Dietary management of epilepsy. In: Livingston S, editor. Comprehensive management of epilepsy in infancy, childhood and adolescence. Springfield, IL: Charles C, Thomas; 1972. p. 378-405.
25. Magrath G, MacDonald A, Whitehouse W. Dietary practices and use of the ketogenic diet in the UK. Seizure 2000;9:128-30.
26. De Vivo DC, Trifiletti RR, Jacobson RI, Ronen GM, Behmand RA, Harik SI. Defective glucose transport across the blood-brain barrier as a cause of persistent hypoglycorrhachia, seizures and developmental delay. N Engl J Med 1991;325:703-9.
27. Sirven J, Whedon B, Caplan D, Liporace J, Gloser D, O'Dwyer J, et al. The ketogenic diet for intractable epilepsy in adults: preliminary results. Epilepsia 1999;40:1721-6.
28. Thompson JA, Van Orman CB, Peterson P. Ketogenic diet: long-term efficacity and patient tolerance in the treatment of intractable pediatric epilepsy [abstract]. Epilepsia 1998;39(Suppl 6):167.
29. Gilbert DL, Pyzik PL, Vining EP, Freeman JM. Medication cost reduction in children on the ketogenic diet: data from a prospective study. J Child Neurol 1999;14:469-71.
30. Marson AG, Kadir ZA, Hutton JL, Chadwick DW. The new antiepileptic drugs: a systematic review of their efficacity and tolerability. Epilepsia 1997;38:859-80.
31. Hopkins IJ, Lynch BC. Use of ketogenic diet in epilepsy in childhood. Aust Paediatr J 1970;6:25-9.
32. Vining EPG, Freeman JM, Ballaban-Gil K. A multi-center study of the efficacity of the ketogenic diet. Arch Neurol 1998;55:1433-7.
33. Bergqvist CAG, Chee C, Lutchka L, Satin-Smith M. Changes in resting energy expenditure and respiratory quotient in children with intractable epilepsy on the ketogenic diet [abstract]. Epilepsia 1998; 167(Suppl 6).
34. Hahn TJ, Halstead LR, De Vivo DC. Disordered mineral metabolism produced by ketogenic diet therapy. Calcif Tissue Int 1979;28:17-22.
35. Tallian KB, Nahata MC, Tsao CY. Role of the ketogenic diet in children with intractable seizures. Ann Pharmacother 1998;32: 349-61.
36. Best TH, Franz DN, Gilbert DL, Nelson DP, Epstein MR. Cardiac complications in pediatric patients on the ketogenic diet. Neurology 2000;54:2328-30.
37. Lin MI, Mitchell WG, Chen LS, Davis KA. Symptomatic camitine depletion is common in children on ketogenic diet [abstract]. Epilepsia 1998;38(Suppl 6):168.
38. Nordli DR, De Vivo DC. The ketogenic diet revisited: back to the future. Epilepsia 1997;38:743-9.
39. Ballaban-Gil K, Callahan C, O'Dell C, Pappo M, Moshe S, Shinnar S. Complications of the ketogenic diet. Epilepsia 1998;39:744-8.
40. Kielb S, Koo HP, Bloom DA, Faerber GJ. Nephrolithiasis associated with the ketogenic diet. J Urol 2000;164:464-6.
41. Betsey D, Sotero de Menezes M, Stapleton B. Nephrolithiasis associated with ketogenic diet treatment [abstract]. Epilepsia 1998;39 (Suppl 6):168.
42. Herzberg GZ, Fivush BA, Kinsman SL, Gearhart JP. Urolithiasis associated with the ketogenic diet. J Pediatr 1990;117:743-5.
43. Theda C, Woody RC, Naidu S, Moser AB, Moser HW. Increased very long chain fatty acid in patients on ketogenic diet: a cause of diagnostic confusion. J Pediatr 1993;122:724-6.