메뉴 건너뛰기




Volumn 38, Issue 8, 1997, Pages 859-880

The new antiepileptic drugs: A systematic review of their efficacy and tolerability

Author keywords

Gabapentin; Lamotrigine; Tiagabine; Topiramate; Vigabatrin; Zonis amide

Indexed keywords

ANTICONVULSIVE AGENT; GABAPENTIN; LAMOTRIGINE; NEW DRUG; PLACEBO; TIAGABINE; TOPIRAMATE; VIGABATRIN; ZONISAMIDE;

EID: 0030873963     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1157.1997.tb01251.x     Document Type: Review
Times cited : (336)

References (38)
  • 2
    • 0029920752 scopus 로고    scopus 로고
    • How easy Are randomized controlled trials in epilepsy to find on Medline? the sensitivity and precision of two Medline searches
    • Marson AG, Chadwick DW. How easy Are randomized controlled trials in epilepsy to find on Medline? The sensitivity and precision of two Medline searches. Epilepsia 1996;37:377-80.
    • (1996) Epilepsia , vol.37 , pp. 377-380
    • Marson, A.G.1    Chadwick, D.W.2
  • 3
    • 0025690059 scopus 로고
    • Farr.
    • Reynolds EH, ed. Vigabatrin: rational treatment for chronic epilepsy
    • Ring HA, Heller AJ, Farr. In: Reynolds EH, ed. Vigabatrin: rational treatment for chronic epilepsy. J Neurol Neurosurg Psychiatry 1990;53(12):1051-5.
    • (1990) J Neurol Neurosurg Psychiatry , vol.53 , Issue.12 , pp. 1051-1055
    • Ring, H.A.1    Heller, A.J.2
  • 4
    • 0027420062 scopus 로고
    • Felbamate: A double blind controlled trial in patients undergoing presurgical evaluation of partial seizures
    • Bourgeois B, Leppik IE, Sackellares JC, et al. Felbamate: a double blind controlled trial in patients undergoing presurgical evaluation of partial seizures. Neurology 1993;43(4):693-6.
    • (1993) Neurology , vol.43 , Issue.4 , pp. 693-696
    • Bourgeois, B.1    Leppik, I.E.2    Sackellares, J.C.3
  • 5
    • 0026662642 scopus 로고
    • Felbamate monotherapy: Controlled trial in patients with partial onset seizures
    • Sachdeo R, Kramer LD, Rosenberg A, Sachdeo S. Felbamate monotherapy: controlled trial in patients with partial onset seizures. Ann Neurol 1992;32(3):386-92.
    • (1992) Ann Neurol , vol.32 , Issue.3 , pp. 386-392
    • Sachdeo, R.1    Kramer, L.D.2    Rosenberg, A.3    Sachdeo, S.4
  • 6
    • 0027536726 scopus 로고
    • Felbamate monotherapy for partial onset seizures: An active control trial
    • Faught E, Sachdeo RC, Remler MP, et al. Felbamate monotherapy for partial onset seizures: an active control trial. Neurology 1993;43(4):688-92.
    • (1993) Neurology , vol.43 , Issue.4 , pp. 688-692
    • Faught, E.1    Sachdeo, R.C.2    Remler, M.P.3
  • 7
    • 0025934106 scopus 로고
    • Felbamate for partial seizures: Results of a controlled clinical trial
    • Leppik IE, Dreifuss FE, Pledger GW, et al. Felbamate for partial seizures: results of a controlled clinical trial. Neurology 1991;41(11):1785-9.
    • (1991) Neurology , vol.41 , Issue.11 , pp. 1785-1789
    • Leppik, I.E.1    Dreifuss, F.E.2    Pledger, G.W.3
  • 8
    • 0025834179 scopus 로고
    • Felbamate: A clinical trial for complex partial seizures
    • Theodore WH, Raubertas RF, Porter RJ, et al. Felbamate: a clinical trial for complex partial seizures. Epilepsia 1991;32(3):392-7.
    • (1991) Epilepsia , vol.32 , Issue.3 , pp. 392-397
    • Theodore, W.H.1    Raubertas, R.F.2    Porter, R.J.3
  • 9
    • 0028120906 scopus 로고
    • Collaborative overview of randomized trials of antiplatelet therapy: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
    • Antiplatelet Trialists' Collaboration. Collaborative overview of randomized trials of antiplatelet therapy: prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ 1994;308:81-106.
    • (1994) BMJ , vol.308 , pp. 81-106
  • 10
    • 0003504721 scopus 로고
    • Meta-analysis decision analysis and cost effectiveness analysis
    • Oxford: Oxford University Press
    • Petitti DB. Meta-analysis decision analysis and cost effectiveness analysis. In: Methods for quantitative synthesis in medicine. Oxford: Oxford University Press, 1984.
    • (1984) Methods for Quantitative Synthesis in Medicine
    • Petitti, D.B.1
  • 12
    • 0028041242 scopus 로고
    • Gabapentin (Neurontin) as add-on therapy in patients with partial seizures: A double-blind, placebo-controlled study: The International Gabapentin Study Group
    • Anhut H, Ashman P, Feuerstein TJ, Sauermann W, Saunders M, Schmidt B. Gabapentin (Neurontin) as add-on therapy in patients with partial seizures: a double-blind, placebo-controlled study: the International Gabapentin Study Group. Epilepsia 1994;35(4):795-801.
    • (1994) Epilepsia , vol.35 , Issue.4 , pp. 795-801
    • Anhut, H.1    Ashman, P.2    Feuerstein, T.J.3    Sauermann, W.4    Saunders, M.5    Schmidt, B.6
  • 13
    • 0026095572 scopus 로고
    • Double blind study of gabapentin in the treatment of partial seizures
    • Sivenius J, Kalviainen R, Ylinen A, Riekkinen P. Double blind study of gabapentin in the treatment of partial seizures. Epilepsia 1991;32(4):539-42.
    • (1991) Epilepsia , vol.32 , Issue.4 , pp. 539-542
    • Sivenius, J.1    Kalviainen, R.2    Ylinen, A.3    Riekkinen, P.4
  • 14
    • 0025343921 scopus 로고
    • Gabapentin in partial epilepsy
    • UK Gabapentin Study Group. Gabapentin in partial epilepsy. Lancet 1990;335(8698):1114-7.
    • (1990) Lancet , vol.335 , Issue.8698 , pp. 1114-1117
  • 15
    • 0027374164 scopus 로고
    • Gabapentin as add-on therapy in refractory partial epilepsy: A double-blind, placebo-controlled, parallel-group study
    • The US Gabapentin Study Group No. 5. Gabapentin as add-on therapy in refractory partial epilepsy: a double-blind, placebo-controlled, parallel-group study. Neurology 1993;43(11):2292-8.
    • (1993) Neurology , vol.43 , Issue.11 , pp. 2292-2298
  • 16
    • 0027491284 scopus 로고
    • Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures: U.S. Lamotrigine Protocol 0.5 Clinical Trial Group
    • Matsuo F, Bergen D, Faught E, et al. Placebo-controlled study of the efficacy and safety of lamotrigine in patients with partial seizures: U.S. Lamotrigine Protocol 0.5 Clinical Trial Group. Neurology 1993;43(11):2284-91.
    • (1993) Neurology , vol.43 , Issue.11 , pp. 2284-2291
    • Matsuo, F.1    Bergen, D.2    Faught, E.3
  • 17
    • 0024453369 scopus 로고
    • Double blind crossover trial of lamotrigine (Lamictal) as add on therapy in intractable epilepsy
    • Binnie CD, Debets RM, Engelsman M, et al. Double blind crossover trial of lamotrigine (Lamictal) as add on therapy in intractable epilepsy. Epilepsy Res 1989;4(3):222-9.
    • (1989) Epilepsy Res , vol.4 , Issue.3 , pp. 222-229
    • Binnie, C.D.1    Debets, R.M.2    Engelsman, M.3
  • 18
    • 0024335018 scopus 로고
    • Controlled trial of lamotrigine (Lamictal) for refractory partial seizures
    • Jawad S, Richens A, Goodwin G, Yuen WC. Controlled trial of lamotrigine (Lamictal) for refractory partial seizures. Epilepsia 1989;30(3):356-63.
    • (1989) Epilepsia , vol.30 , Issue.3 , pp. 356-363
    • Jawad, S.1    Richens, A.2    Goodwin, G.3    Yuen, W.C.4
  • 19
    • 0025087187 scopus 로고
    • A randomised double blind placebo controlled cross-over add on trial of lamotrigine in patients with treatment resistant partial seizures
    • Loiseau P, Yuen AW, Duche B, Menager T, Arne Bes MC. A randomised double blind placebo controlled cross-over add on trial of lamotrigine in patients with treatment resistant partial seizures. Epilepsy Res 1990;7(2):136-45.
    • (1990) Epilepsy Res , vol.7 , Issue.2 , pp. 136-145
    • Loiseau, P.1    Yuen, A.W.2    Duche, B.3    Menager, T.4    Arne Bes, M.C.5
  • 20
    • 0028268250 scopus 로고
    • Lamotrigine therapy for partial seizures: A multicenter, placebo-controlled, double-blind, cross-over trial
    • Messenheimer J, Ramsay RE, Willmore LJ, et al. Lamotrigine therapy for partial seizures: a multicenter, placebo-controlled, double-blind, cross-over trial. Epilepsia 1994;35(1):113-21.
    • (1994) Epilepsia , vol.35 , Issue.1 , pp. 113-121
    • Messenheimer, J.1    Ramsay, R.E.2    Willmore, L.J.3
  • 21
    • 0027254062 scopus 로고
    • Double blind, placebo controlled, cross-over study of lamotrigine in treatment resistant partial seizures
    • Schapel GJ, Beran RG, Vajda FJ, et al. Double blind, placebo controlled, cross-over study of lamotrigine in treatment resistant partial seizures. J Neurol Neurosurg Psychiatry 1993;56(5):448-53.
    • (1993) J Neurol Neurosurg Psychiatry , vol.56 , Issue.5 , pp. 448-453
    • Schapel, G.J.1    Beran, R.G.2    Vajda, F.J.3
  • 22
    • 0027534819 scopus 로고
    • Outcomes of add on treatment with lamotrigine in partial epilepsy
    • Smith D, Baker G, Davies G, Dewey M, Chadwick DW. Outcomes of add on treatment with lamotrigine in partial epilepsy. Epilepsia 1993;34(2):312-22.
    • (1993) Epilepsia , vol.34 , Issue.2 , pp. 312-322
    • Smith, D.1    Baker, G.2    Davies, G.3    Dewey, M.4    Chadwick, D.W.5
  • 23
    • 0029997934 scopus 로고    scopus 로고
    • A double-blind, placebo controlled study of vigabatrin 3 g/day in patients with uncontrolled complex partial seizures
    • French JA, Mosier M, Walker S, Somerville K, Sussman N, and the Vigabatrin Protocol 024 Investigative Cohort. A double-blind, placebo controlled study of vigabatrin 3 g/day in patients with uncontrolled complex partial seizures. Neurology 1996;46:54-61.
    • (1996) Neurology , vol.46 , pp. 54-61
    • French, J.A.1    Mosier, M.2    Walker, S.3    Somerville, K.4    Sussman, N.5
  • 25
    • 0002368859 scopus 로고
    • Multicenter dose-response sstudy of vigabatrin in adults with focal (partial) epilepsy
    • Abstract (Hoechst Marrion Roussel)
    • Penry JK, Wilder BJ, Rajesh C, et al. Multicenter dose-response sstudy of vigabatrin in adults with focal (partial) epilepsy. Epilepsia 1993;34(suppl 6):67. Abstract (Hoechst Marrion Roussel).
    • (1993) Epilepsia , vol.34 , Issue.SUPPL. 6 , pp. 67
    • Penry, J.K.1    Wilder, B.J.2    Rajesh, C.3
  • 26
    • 0027180811 scopus 로고
    • Zonisamide for add on treatment of refractory partial epilepsy: A European double blind trial
    • Schmidt D, Jacob R, Loiseau P, et al. Zonisamide for add on treatment of refractory partial epilepsy: a European double blind trial. Epilepsy Res 1993;15(1):67-73.
    • (1993) Epilepsy Res , vol.15 , Issue.1 , pp. 67-73
    • Schmidt, D.1    Jacob, R.2    Loiseau, P.3
  • 29
    • 0000722175 scopus 로고
    • Vigabatrin versus hydrocortisone as first-line monotherapy in infantile spasms due to tuberous sclerosis
    • Chiron C, Dumas C, Dulac O, et al. Vigabatrin versus hydrocortisone as first-line monotherapy in infantile spasms due to tuberous sclerosis. Epilepsia 1995;(36 suppl 3):S265.
    • (1995) Epilepsia , Issue.36 SUPPL. 3
    • Chiron, C.1    Dumas, C.2    Dulac, O.3
  • 30
    • 0021188579 scopus 로고
    • Validation of the phenomenon of regresssion of seizure frequency in epilepsy
    • Spilker B, Segreti A. Validation of the phenomenon of regresssion of seizure frequency in epilepsy. Epilepsia 1984;25(4):443-9.
    • (1984) Epilepsia , vol.25 , Issue.4 , pp. 443-449
    • Spilker, B.1    Segreti, A.2
  • 32
    • 0026009636 scopus 로고
    • A general parametric approach to the meta-analysis of randomized clinical trials
    • Whitehead A, Whitehead J. A general parametric approach to the meta-analysis of randomized clinical trials. Stat Med 1991;10:1677-77.
    • (1991) Stat Med , vol.10 , pp. 1677-1677
    • Whitehead, A.1    Whitehead, J.2
  • 33
    • 0012861285 scopus 로고
    • Depakote adjunctive therapy in the treatment of partial seizures
    • Willmore JL. Depakote adjunctive therapy in the treatment of partial seizures. Epilepsia 1995;36(suppl 3):S66.
    • (1995) Epilepsia , vol.36 , Issue.SUPPL. 3
    • Willmore, J.L.1
  • 34
    • 0029651761 scopus 로고
    • Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy
    • Brodie MJ, Richens A, Yuen AWC. Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy. Lancet 1995;(345):476-9.
    • (1995) Lancet , Issue.345 , pp. 476-479
    • Brodie, M.J.1    Richens, A.2    Yuen, A.W.C.3
  • 35
    • 0021887675 scopus 로고
    • Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures
    • Mattson RH, Cramer JA, Collins JF, et al. Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. N Engl J Med 1985;313(3):145-51.
    • (1985) N Engl J Med , vol.313 , Issue.3 , pp. 145-151
    • Mattson, R.H.1    Cramer, J.A.2    Collins, J.F.3
  • 36
    • 0029057901 scopus 로고
    • Antiepileptic drug mechanisms of action
    • MacDonald RL, Kelly KM. Antiepileptic drug mechanisms of action. Epilepsia 1995;36(suppl 2):S2-12.
    • (1995) Epilepsia , vol.36 , Issue.SUPPL. 2
    • MacDonald, R.L.1    Kelly, K.M.2
  • 38
    • 0028219830 scopus 로고
    • Guidelines for antiepileptic drug trials in children
    • Commission on Antiepileptic Drugs of the International League Against Epilepsy. Guidelines for antiepileptic drug trials in children. Epilepsia 1994;35(1):94-100.
    • (1994) Epilepsia , vol.35 , Issue.1 , pp. 94-100


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.