A Mucor rouxii mutant with high accumulation of an unusual trans-linoleic acid (9c,12t-C18:2)

FEMS Microbiology Letters

Volumn 223, Issue 2, 2003, Pages 159-165

  Laoteng, Kobkul ^a   Pongchuachidthai, Rapeepun ^a   Rueksomtawin, Kanchana ^a   Dandusitapunth, Yuwapin ^a   Tanticharoen, Morakot ^a   Cheevadhanarak, Supapon ^a  

^a KING MONGKUT'S UNIVERSITY OF TECHNOLOGY THONBURI   (Thailand)

Author keywords

Fatty acid desaturation; Linoleic acid; Mucor rouxii; Mutant; trans Unsaturated fatty acid; Linolenic acid

Indexed keywords

GAMMA LINOLENIC ACID; LINOLEIC ACID;

ARTICLE; CIS TRANS ISOMERISM; CONTROLLED STUDY; ENRICHMENT CULTURE; FATTY ACID ANALYSIS; FATTY ACID DESATURATION; FILTRATION; FUNGUS CULTURE; FUNGUS MUTANT; GENETIC ANALYSIS; LIPID COMPOSITION; LOW TEMPERATURE PROCEDURES; MUCOR; MUCOR ROUXII; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SUPPLEMENTATION; ULTRAVIOLET RADIATION;

AMYLOMYCES ROUXII; FUNGI; MUCOR; MUCOR ROUXII;

EID: 0038771956     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(03)00324-0     Document Type: Article

References (32)

1. White J.A., Benning C. Genomic approaches towards the engineering of oil seeds. Plant Physiol. Biochem. 139:2001;363-370.
2. Thelen J.J., Ohlrogge J.B. Metabolic engineering of fatty acid biosynthesis in plants. Metab. Eng. 4:2002;12-21.
3. Murphy D.J. Production of novel oils in plants. Curr. Opin. Biotechnol. 10:1999;175-180.
4. Gunstone F.D. Gamma linolenic acid - occurrence and physical and chemical properties. Prog. Lipid Res. 31:1992;145-161.
5. Alonso D.L., Maroto F.G. Plants as chemical factories for the production of polyunsaturated fatty acids. Biotechnol. Adv. 18:2000;481-497.
6. Gill I., Valivety R. Polyunsaturated fatty acids, part 1: occurrence, biological activities and applications. Trends Biotechnol. 15:1997;401-409.
7. 5-monounsaturated fatty acids by bacteria. J. Biol. Chem. 239:1964;998-1003.
8. Certik M., Shimizu S. Biosynthesis and regulation of microbial polyunsaturated fatty acid production. J. Biosci. Bioeng. 87:1999;1-14.
9. Hansson L., Dostalek M., Sorenby B. Production of γ-linolenic acid by the fungus Mucor rouxii in fed-batch and continuous culture. Appl. Microbiol. Biotechnol. 31:1989;223-227.
10. Mukherjee K.D. Production and use of microbial oils. Inform. 10:1999;308-313.
11. 9-desaturase gene is transcriptionally regulated during cell growth and by low temperature. Mol. Cell. Biol. Res. Commun. 1:1999;36-43.
12. 12-desaturase gene in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 263:1999;47-51.
13. 6-desaturase and its heterologous expression in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 279:2000;17-22.
14. Catcheside D.G. Isolation of nutritional mutants of Neurospora crassa by filtration enrichment. J. Gen. Microbiol. 11:1954;34-36.
15. 9-desaturase. Can. J. Microbiol. 31:1985;346-351.
16. Stearns T., Ma H., Botstein D. Manipulating yeast genome using plasmid vectors. Methods Enzymol. 185:1990;280-297.
17. Lepage G., Roy C.C. Improved recovery of fatty acid through direct transesterification without prior extraction or purification. J. Lipid Res. 25:1984;1391-1396.
18. Carratu L., Francheschelli S., Pardini C.L., Kobayashi G.S., Horvath I., Vigh L., Maresca B. Membrane lipid perturbation modifies the set point of the temperature of heat shock response in yeast. Proc. Natl. Acad. Sci. USA. 93:1996;2120-2125.
19. Cossins, A.R. (1994) Homeoviscous adaptation of biological membranes and its functional significance. In: Temperature Adaptation of Biological Membranes (Cossins, A.R., Ed.), pp. 63-76. Portland Press, London.
20. Vigh L., Maresca B., Harwood J. Does the membrane's physical state control the expression of heat shock and other genes? Trends Biochem. Sci. 23:1998;369-374.
21. Kodama H., Hamada T., Horiguchi G., Nishimura M., Iba K. Genetic enhancement of cold tolerance by expression of a gene for chloroplast ω3-fatty acid desaturase in transgenic tobacco. Plant Physiol. 105:1994;601-605.
22. Nishida I., Murata N. Chilling sensitivity in plants and cyanobacteria: the crucial contribution of membrane lipids. Annu. Rev. Plant Physiol. Plant Mol. Biol. 47:1996;541-568.
23. Murata N., Los D.A. Membrane fluidity and temperature perception. Plant Physiol. 115:1997;560-564.
24. Wallis J.G., Browse J. Mutants of Arabidopsis reveal many roles for membrane lipids. Prog. Lipid Res. 41:2002;254-278.
25. Iba K., Gibson S., Nishiuchi T., Fuse T., Nishimura M., Arondel V., Hugly S., Somerville C. A gene encoding a chloroplast ω-3 fatty acid desaturase complements alterations in fatty acid desaturation and chloroplast copy number of the fad7 mutant of Arabidopsis thaliana. J. Biol. Chem. 268:1993;24099-24105.
26. Anamnart S., Tolstorukov I., Kaneko Y., Harashima S. Fatty acid desaturation in methylotrophic yeast Hansenula polymorpha strain CBS 1976 and unsaturated fatty acid auxotrophic mutants. J. Ferment. Bioeng. 85:1998;476-482.
27. Avelange-Macherel M.-H., Macherel D., Wada H., Murata N. Site-directed mutagenesis of histidine residues in the Δ12 acyl-lipid desaturase of Synechocystis. FEBS Lett. 361:1995;111-114.
28. Keweloh H., Heipieper H.J. Trans unsaturated fatty acids in bacteria. Lipids. 31:1996;129-137.
29. Holtwick R., Keweloh H., Meinhardt F. Cis/trans isomerase of unsaturated fatty acids of Pseudomonas putida P8: Evidence for a heme protein of the cytochrome c type. Appl. Environ. Microbiol. 65:1999;2644-2649.
30. Diefenbach R., Heipieper H.-J., Keweloh H. The conversion of cis into trans unsaturated fatty acids in Pseudomanas putida P8: evidence for a role in the regulation of membrane fluidity. Appl. Microbiol. Biotechnol. 38:1992;382-387.
31. Ackman R.G., Hooper S.N., Hooper D.L. Linolenic acid artifacts from the deodorization of oils. J. Am. Oil Chem. Soc. 51:1974;42-49.
32. Dyer J.M., Chaptital D.C., Kuan J.W., Mullen R.T., Turner C., McKeon T.A., Pepperman A.B. Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung: implications for the evolution of plant fatty acid diversity. Plant Physiol. 130:2002;2027-2038.