Phosphorylation of β-D-ribosylbenzimidazoles is not required for activity against human cytomegalovirus

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 2, 2002, Pages 478-486

  Krosky, Paula M ^a   Borysko, Katherine Z ^a   Nassiri, M Reza ^a   Devivar, Rodrigo V ^a   Ptak, Roger G ^a   Davis, Michelle G ^a   Biron, Karen K ^a   Townsend, Leroy B ^a   Drach, John C ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 BROMO 5,6 DICHLORO 1 (BETA DEXTRO RIBOFURANOSYL)BENZIMIDAZOLE; 2 BROMO 5,6 DICHLORO 1 (BETA DEXTRO RIBORUFANOSYL)BENZIMIDAZOLE 5' MONOPHOSPHATE; 2,5,6 TRICHLORO 1 (BETA DEXTRO RIBOFURANOSYL)BENZIMIDAZOLE; 5' DEOXY 2,5,6 TRICHLORO 1 (BETA DEXTRO RIBOFURANOSYL)BENZIMIDAZOLE; ALKALINE PHOSPHATASE; ANTIVIRUS AGENT; BENZIMIDAZOLE DERIVATIVE; DRUG METABOLITE; RIBONUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANION EXCHANGE CHROMATOGRAPHY; ANTIVIRAL ACTIVITY; ARTICLE; CYTOMEGALOVIRUS INFECTION; DNA SYNTHESIS INHIBITION; DRUG EFFECT; DRUG EFFICACY; DRUG METABOLISM; DRUG POTENCY; DRUG SELECTIVITY; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; VIRUS GENOME; VIRUS INHIBITION;

ANTIVIRAL AGENTS; BENZIMIDAZOLES; CYTOMEGALOVIRUS; DNA; DRUG RESISTANCE, MICROBIAL; HUMANS; PHOSPHORYLATION; RIBONUCLEOSIDES; RNA; TUMOR CELLS, CULTURED;

EID: 0036150159     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.2.478-486.2002     Document Type: Article

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