Modulation of p53 after maternal exposure to all-trans-retinoic acid in Swiss Webster mouse fetuses

Experimental and Molecular Pathology

Volumn 74, Issue 3, 2003, Pages 298-308

  Sarkar, Suparna A ^a,b   Sharma, Raghubir P ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF COLORADO DENVER   (United States)

Author keywords

Histochemistry; Mouse; Organogenesis; p21; p27; p53; Retinoic acid; Teratogenesis

Indexed keywords

MESSENGER RNA; PROTEIN P21; PROTEIN P27; PROTEIN P53; RETINOIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CELL DISRUPTION; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; DEVELOPMENTAL DISORDER; FEMALE; FETUS; FETUS DEVELOPMENT; FETUS WEIGHT; IMMUNOHISTOCHEMISTRY; MOUSE; NEUROEPITHELIUM; NONHUMAN; ORGANOGENESIS; PRENATAL EXPOSURE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STEM CELL; TERATOGENESIS; TISSUE LEVEL;

MURINAE;

EID: 0038730988     PISSN: 00144800     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4800(02)00018-7     Document Type: Article

References (44)

1. Alles A.J., Sulik K.K. Retinoic-acid-induced limb-reduction defects perturbation of zones of programmed cell death as a pathogenetic mechanism . Teratology. 40:1989;163-171.
2. Almog N., Rotter V. Involvement of p53 in cell differentiation and development. Biochim. Biophys. Acta. 1333:1997;F1-27.
3. Armstrong J.F., Kaufman M.H., Harrison D.J., Clarke A.R. High-frequency developmental abnormalities in p53-deficient mice. Curr. Biol. 5:1995;931-936.
4. Armstrong R.B., Ashenfelter K.O., Eckhoff C., Levin A.A., Shapiro S.S. General and reproductive toxicology of retinoids. Sporn M.B., Roberts A.B., Goodman D.S. The Retinoids. 1994;545-572 Raven Press, New York.
5. Choi J., Donehower L.A. p53 in embryonic development maintaining a fine balance . Cell. Mol. Life Sci. 55:1999;38-47.
6. Deryckere F., Gannon F. A one-hour mini preparation technique for extraction of DNA-binding proteins from animal tissues. Biotechniques. 16:1994;405.
7. Donehower L.A., Harvey M., Slagle B.T., McArthur M.J., Montgomery C.A., Butel J.S., Bradly A. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature. 356:1992;215-221.
8. Dulic V., Kaufmann W.K., Wilson S.J., Tlsty T.D., Lees E., Harper J.W., Elledge S.J., Reed S.I. p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell. 76:1994;1013-1023.
9. El-Deiry W.S., Tokino T., Velculescu V., Levy D.B., Parson R., Trent J.M. WAF1, a potential mediator of p53 tumor suppressor. Cell. 75:1993;817-825.
10. Gartel A.L., Tyner A.L. Transcriptional regulation of the p21 (WAF1/CIP1) gene. Exp. Cell Res. 246:1999;280-289.
11. Gottlieb T.M., Oren M. P53 in growth control and neoplasia. Biochim. Biophys. Acta. 1287:1996;77-102.
12. Harper J.W., Adami G.R., Wei N., Keyomarsi K., Elledge S.J. The p21 CDK interacting protein cip1 is a potent inhibitor of G1 cyclin dependent kinase. Cell. 75:1993;805-816.
13. Horton C., Maden M. Endogenous distribution of retinoids during normal development and teratogenesis in the mouse embryo. Dev. Dyn. 202:1995;312-323.
14. Kato F., Ootsuyama A., Nomoto S., Kondo S., Norimura T. Threshold effect for teratogenic risk of radiation depends on dose-rate and p53-dependent apoptosis. Int. J. Radiat. Biol. 77:2001;13-19.
15. Khochbin S., Brocard M.P., Grunwald D., Lawrence J.J. Antisense RNA and p53 regulation in induced murine cell differentiation. Ann. N.Y. Acad. Sci. 660:1992;77-87.
16. Ko L.J., Prives C. p53 Puzzle and paradigm . Genes Dev. 10:1996;1054-1072.
17. Kochhar D.M., Penner J.D., Satre M.A. Derivation of retinoic acid and metabolites from a teratogenic dose of retinol (vitamin A) in mice. Toxicol. Appl. Pharmacol. 96:1988;429-441.
18. Lammer E.J., Chen D.T., Hoar R.M., Agnish N.D., Benke P.J., Braun J.T., Curry C.J., Fernhoff P.M., Grix A.W. Jr., Lott I.T., Richard J., Sun S. Retinoic acid embryopathy. N. Engl. J. Med. 313:1985;837-841.
19. Leid M., Kastner P., Chambon P. Multiplicity generates diversity in the retinoic acid signaling pathways. Trends Biochem. Sci. 17:1992;427-433.
20. Lichnovsky V., Kolar Z., Murray P., Hlobilkova A., Cernochova D., Pospisilova E., Vojtesek B., Nenutil R. Differences in p53 and Bcl-2 expression in relation to cell proliferation during the development of human embryos. Mol. Pathol. 51:1998;131-137.
21. Lotan R. Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells. Biochim. Biophys. Acta. 605:1980;33-91.
22. Mora P.T., Chandrasekaran K., McFarland V.W. An embryo protein induced by SV40 virus transformation of mouse cells. Nature. 288:1980;722-724.
23. Morriss G.M. An electron microscopic study of the effects of hypervitaminosis A on the maternal-embryonic relationship of the rat at 8 days of pregnancy. J. Reprod. Fertil. 33:1973;451-456.
24. Nakayamak K., Ishida N., Shirane M., Inomata A., Inoue T., Shishido N., Horii I., Loh D.Y., Nakayama K. Mice lacking p27 (Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell. 85:1996;707-720.
25. Nicol C.J., Harrison M.L., Laposa R.R., Gimelshtein I.L., Wells P.G. A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice. Nat. Genet. 10:1995;181-187.
26. Norimura T., Nomoto S., Katsuki M., Gondo Y., Kondo S. p53-dependent apoptosis suppresses radiation-induced teratogenesis. Nat. Med. 2:1996;577-580.
27. Ozeki H., Shirai S. Developmental eye abnormalities in mouse fetuses induced by retinoic acid. Jpn. J. Ophthalmol. 42:1998;162-167.
28. Pauken C.M., LaBorde J.B., Bolon B. Retinoic acid acts during peri-implantational development to alter axial and brain formation. Anat. Embryol. (Berl.). 200:1999;645-655.
29. Pillans P.I., Folb P.I., Ponzi S.F. The effects of in vivo administration of teratogenic doses of vitamin A during the preimplantation period in the mouse. Teratology. 37:1988;7-11.
30. Poulaki V., Benekou A., Bozas E., Bolaris S., Stylianopoulou F. P53 expression and regulation by NMDA receptors in the developing rat brain. J. Neurosci. Res. 56:1999;427-440.
31. Rogel A., Poplinker M., Webb S.G., Oren M. P53 cellular tumor antigen Analysis of mRNA levels in normal adult tissues and tumors . Mol. Cell. Biol. 5:1985;2851-2855.
32. Rutledge J.C., Shourbaji A.G., Hughes L.A., Polifka J.E., Cruz Y.P., Bishop J.B., Generoso W.M. Limb and lower-body duplications induced by retinoic acid in mice. Proc. Natl. Acad. Sci. USA. 91:1994;5436-5440.
33. Sah V.P., Attardi L.D., Mulligan G.J., Williams B.O., Bronson R.T., Jacks T.A. Subset of p53-deficient embryos exhibit exencephaly. Nat. Genet. 10:1995;175-180.
34. Sarkar S.A., Sharma R.P. Expression of c-Myc and other apoptosis-related genes in Swiss Webster mouse fetuses after maternal exposure to all-trans-retinoic acid. Reprod. Toxicol. 16:2002;245-252.
35. Sarkar S.A., Sharma R.P. All-trans-retinoic acid-mediated modulation of p53 during neural differentiation in murine embryonic stem cells. Cell Biol. Toxicol. 18:2002;243-257.
36. Schmid P., Lorenz A., Hameister H., Montenarh M. Expression of p53 during mouse embryogenesis. Development. 113:1991;857-865.
37. Sharma R.P., Bhandari N., Riley R.T., Voss K.A., Meredith F.I. Tolerance to fumonisin toxicity in a mouse strain lacking the P75 tumor necrosis factor receptor. Toxicology. 143:2000;183-194.
38. Shenefelt R.E. Morphogenesis of malformations in hamsters caused by retinoic acid relation to dose and stage at treatment . Teratology. 5:1972;103-118.
39. Tendler Y., Weisinger G., Coleman R., Diamond E., Lischinsky S., Kerner H., Rotter V., Zinder O. Tissue-specific p53 expression in the nervous system. Brain Res. Mol. Brain Res. 72:1999;40-46.
40. van Lookeren Campagne M., Gill R. Tumor-suppressor p53 is expressed in proliferating and newly formed neurons of the embryonic and postnatal rat brain comparison with expression of the cell cycle regulators p21Waf1/Cip1, p27Kip1, p57Kip2, p16Ink4a, cyclin G1, and the proto-oncogene Bax . J. Comp. Neuro. 397:1998;181-198.
41. Waga S., Hannon G.J., Beach D., Stillman B. The p21 inhibitor of cyclin dependent kinases controls DNA replication by interacting with PCNA. Nature. 371:1994;534-537.
42. Wubah J.A., Ibrahim M.M., Gao X., Nguyen D., Pisano M.M., Knudsen T.B. Teratogen-induced eye defects mediated by p53-dependent apoptosis. Curr. Biol. 6:1996;60-69.
43. Xiong Y., Hannon G.J., Zhang H., Casso D., Kobayashi R., Beach D. P21 is a universal inhibitor of cyclin kinases. Nature. 366:1993;701-704.
44. Yamagata T., Momoi M.Y., Yanagisawa M., Kumagai H., Yamakado M., Momoi T. Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos. Brain Res. Dev. Brain Res. 77:1994;163-176.