Lysine-313 of 5-aminolevulinate synthase acts as a general base during formation of the quinonoid reaction intermediates

Biochemistry

Volumn 38, Issue 12, 1999, Pages 3711-3718

  Hunter, Gregory A ^a   Ferreira, Gloria C ^a,b  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINOLEVULINATE SYNTHASE; HISTIDINE; LYSINE; QUINONE DERIVATIVE;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME MECHANISM; HEME SYNTHESIS; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PURIFICATION; REACTION ANALYSIS;

5-AMINOLEVULINATE SYNTHETASE; ACYL COENZYME A; AMINOLEVULINIC ACID; CATALYSIS; GLYCINE; LYSINE; MUTAGENESIS; SPECTRUM ANALYSIS; TRITIUM;

ANIMALIA; MURINAE; TRITIUM;

EID: 0033596947     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982390w     Document Type: Article

References (37)

1. May, B. K., Dogra, S. C., Sadlon, T. J., Bhasker, C. R., Cox, T. C., and Bottomley, S. S. (1995) Prog. Nucleic Acid. Res. Mol. Biol. 51, 1-51.
2. Ferreira, G. C., and Gong, J. (1995) J. Bioenerg. Biomembr. 27, 151-159.
3. Rohde, M., Srivastava, G., Rylatt, D. B., Bundesen, P., Zamattia, J., Crane, D. I., and May, B. K. (1990) Arch. Biochem. Biophys. 280, 331-335.
4. Bottomley, S. S., May, B. K., Cox, T. C., Cotter, P. D., and Bishop, D. F. (1995) J. Bioenerg. Biomembr. 27, 161-168.
5. Grishin, N. V., Phillips, M. A., and Goldsmith, E. J. (1995) Protein Sci. 4, 1291-1304.
6. Alexander, F. W., Sandmeier, E., Mehta, P. K., and Christen, P. (1994) Eur. J. Biochem. 219, 953-960.
7. Metzler, D. E., Longenecker, J. B., and Snell, E. E. (1954) J. Am. Chem. Soc. 76, 639-644.
8. John, R. A. (1995) Biochim. Biophys. Acta 1248, 81-96.
9. Metzler. C. M., Harris, A. G., and Metzler, D. E. (1988) Biochemistry 27, 4923-4933.
10. Phillips, R. S., Sundararaju, B., and Koushik, S. V. (1998) Biochemistry 37, 8783-8789.
11. Jhee, K. H., Yang, L. H., Ahmed, S. A., McPhie, P., Rowlett, R., and Miles, E. W. (1998) J. Biol. Chem. 273, 11417-11422.
12. Gong, J., Hunter, G. A., and Ferreira, G. C. (1998) Biochemistry 37, 3509-3517.
13. Sun, S., Bagdassarian, C. K., and Toney, M. D. (1998) Biochemistry 37, 3876-3885.
14. Toney, M. D., and Kirsch, J. F. (1991) J. Biol. Chem. 266, 23900-23903.
15. Phillips, R. S., Richter, I., Gollnick, P., Brzovic, P., and Dunn, M. F. (1991) J. Biol. Chem. 266, 18642-18648.
16. Toney, M. D., and Kirsch, J. F. (1993) Biochemistry 32, 1471-1479.
17. Lu, Z., Nagata, S., McPhie, P., and Miles, E. W. (1993) J. Biol. Chem. 268, 8727-8734.
18. Rege, V. D., Kredich, N. M., Tai, C. H., Karsten, W. E., Schnackerz, K. D., and Cook, P. F. (1996) Biochemistry 35, 13485-13493.
19. Yoshimura, T., Bhatia, M. B., Manning, J. M., Ringe, D., and Soda, K. (1992) Biochemistry 31, 11748-11754.
20. Cordes, E. H., and Jencks, W. P. (1962) Biochemistry 1, 773-778.
21. Toney, M. D., and Kirsch, J. F. (1989) Science 243, 1485-1488.
22. Ahktar, M., and Jordan, P. M. (1979) in Comprehensive organic chemistry: the synthesis and reactions of organic compounds (Haslam, E., Ed.) pp 1121-1144, Pergamon Press, Oxford, New York.
23. Ferreira, G. C., Neame, P. J., and Dailey, H. A. (1993) Protein Sci. 2, 1959-1965.
24. Ferreira, G. C., Vajapey, U., Hafez, O., Hunter, G. A., and Barber, M. J. (1995) Protein Sci. 4, 1001-1006.
25. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular cloning: a laboratory manual, 2nd ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
26. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463-5467.
27. Ferreira, G. C., and Dailey, H. A. (1993) J. Biol. Chem. 268, 584-590.
28. Laemmli, U. K. (1970) Nature 227, 680-685.
29. Hunter, G. A., and Ferreira, G. C. (1995) Anal. Biochem. 226, 221-224.
30. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Anal. Biochem. 150, 76-85.
31. Nandi, D. L. (1978) J. Biol. Chem. 253, 8872-8877.
32. Jordan, P. M., and Laghai, A. (1976) Biochem. Soc. Trans. 4, 52-53.
33. Laghai, A., and Jordan, P. M. (1977) Biochem. Soc. Trans. 5, 299-301.
34. Zaman, Z., Jordan, P. M., and Akhtar, M. (1973) Biochem. J. 135, 257-263.
35. Ziak, M., Jaussi, R., Gehring, H., and Christen, P. (1990) Eur. J. Biochem. 187, 329-333.
36. Ziak, M., Jager, J., Malashkevich, V. N., Gehring, H., Jaussi, R., Jansonius, J. N., and Christen, P. (1993) Eur. J. Biochem. 211, 475-484.
37. Cook, P. F., Hara, S., Nalabolu, S., and Schnackerz, K. D. (1992) Biochemistry 31, 2298-2303.