Effect of clonidine on lidocaine clearance in vivo: A microdialysis study in humans

Anesthesiology

Volumn 95, Issue 6, 2001, Pages 1371-1376

  Kopacz, Dan J ^a,b   Bernards, Christopher M ^b  

^a VIRGINIA MASON MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLONIDINE; LIDOCAINE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG CLEARANCE; DRUG POTENTIATION; DRUG TISSUE LEVEL; EXTRACELLULAR FLUID; FEMALE; HUMAN; HUMAN EXPERIMENT; LASER DOPPLER FLOWMETRY; LOCAL ANESTHESIA; MALE; MICRODIALYSIS; NERVE BLOCK; NORMAL HUMAN; PERONEUS NERVE; PHARMACODYNAMICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKIN BLOOD FLOW;

EID: 0035208668     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200112000-00015     Document Type: Article

References (22)

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5. Effects of epinephrine and clonidine on plasma concentrations of spinal bupivacaine
6. Clonidine and or adrenaline decrease lignocaine plasma peak concentration after epidural injection
7. Clonidine administered as an axillary block does not affect postoperative pain when given as a sole analgesic
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11. 2 adrenoreceptor agonists: Defining the role in clinical anesthesia
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14. Peripheral analgesic action of clonidine: Mediation by release of endogenous enkephalin-like substances
15. Clonidine administered as an axillary block does not affect postoperative pain when given as the sole analgesic
16. Comparison of intravenous and epidural clonidine for postoperative patient-controlled analgesia
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20. Postoperative analgesia after peripheral nerve block for podiatric surgery: Clinical efficacy and chemical stability of lidocaine alone versus lidocaine plus clonidine
21. Small-dose clonidine prolongs postoperative analgesia after sciatic-femoral nerve block with 0.75% ropivacaine for foot surgery
22. Dose-range effects of clonidine added to lidocaine for brachial plexus block