Deferiprone (L1) as an adjuvant therapy for Plasmodium falciparum malaria

Indian Journal of Medical Research

Volumn 115, Issue JAN., 2002, Pages 17-21

  Mohanty, D ^a   Ghosh, K ^a   Pathare, A V ^a   Karnad, D ^a  

^a KEM HOSPITAL   (India)

Author keywords

Adjuvant therapy; Deferiprone; Falciparum malaria; Iron chelation; Plasmodium falciparum

Indexed keywords

DEFERIPRONE; DOXYCYCLINE; IRON CHELATING AGENT; PLACEBO; QUININE; ANTIMALARIAL AGENT; PYRIDONE DERIVATIVE;

ADJUVANT THERAPY; ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEATH; DISEASE COURSE; DISEASE SEVERITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG CAPSULE; DRUG TOLERABILITY; FEMALE; FEVER; HUMAN; MALARIA; MALE; MORTALITY; OUTCOMES RESEARCH; PARASITEMIA; PLASMODIUM FALCIPARUM; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; ANIMAL; DRUG COMBINATION; DRUG EFFECT; INDIA; MALARIA FALCIPARUM; MIDDLE AGED;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMAL; ANTIMALARIALS; COMA; DOUBLE-BLIND METHOD; DOXYCYCLINE; DRUG THERAPY, COMBINATION; FEMALE; HUMAN; INDIA; IRON CHELATING AGENTS; MALARIA, FALCIPARUM; MALE; MIDDLE AGE; PLACEBOS; PLASMODIUM FALCIPARUM; PROSPECTIVE STUDIES; PYRIDONES; QUININE; ANIMALS; HUMANS; MIDDLE AGED;

EID: 0035986016     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Effect of iron chelation therapy on recovery from deep coma in children with cerebral malaria
2. Iron chelation with desferrioxamine B in adults with asymptomatic Plasmodium falciparum parasitemia
3. Plasmocidal effect of desferrioxamine B in human vivax or falciparum malaria from Thailand
4. Clinical studies of iron chelators in malaria
5. Preliminary report on the use of desferrioxamine in the treatment of Plasmodium falciparum malaria
6. Comparative efficacy and toxicity of desferrioxamine, deferiprone and other iron and aluminium chelating drugs
7. Trauma of the head and spine
8. False-positive serological tests in acute malaria
9. Iron chelating agents for treating malaria
10. Assessment of the effect of the oral iron chelator deferiprone on asymptomatic Plasmodium falciparum parasitaemia in humans
11. A reappraisal of the effects of iron and desferrioxamine on the growth of Plasmodium falciparum 'in vitro': The unimportance of serum iron
12. A transferrin-independent iron uptake activity in Plasmodium falciparum - Infected and uninfected erythrocytes
13. Iron chelation therapy for malaria: A review
14. Cerebral and ocular toxicity induced by desferrioxamine
15. Control of disease by selective iron depletion: A novel therapeutic strategy utilising iron chelators
16. Differential cytotoxicity of iron chelators on malaria infected cells versus mammalian cells