Na+ channel mutation leading to loss of function and non-progressive cardiac conduction defects

Journal of Molecular and Cellular Cardiology

Volumn 35, Issue 5, 2003, Pages 549-557

  Herfst, Lucas J ^a   Potet, Franck ^b   Bezzina, Connie R ^c   Groenewegen, W Antoinette ^a   Le Marec, Hervé ^b   Hoorntje, Theo M ^a   Demolombe, Sophie ^b   Baró, Isabelle ^b   Escande, Denis ^b   Jongsma, Habo J ^a   Wilde, Arthur A M ^c   Rook, Martin B ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b HÔTEL DIEU   (France)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Brugada syndrome; Cardiac conduction defect; Cardiac sodium channel; Familial heart block; Len gre Lev disease; Nav 1.5; SCN5A

Indexed keywords

GENE PRODUCT; HYBRID PROTEIN; MUTANT PROTEIN; PROTEIN SUBUNIT; SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; ATRIOVENTRICULAR BLOCK; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; ELECTROCARDIOGRAM; FEMALE; FRAMESHIFT MUTATION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC CODE; HEART FUNCTION; HEART MUSCLE CONDUCTION DISTURBANCE; HEART VENTRICLE CONDUCTION; HUMAN; HUMAN CELL; MALE; MAMMAL CELL; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; SODIUM CURRENT; STOP CODON; VOLTAGE CLAMP; XENOPUS LAEVIS;

MAMMALIA; XENOPUS LAEVIS;

EID: 0038637901     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2828(03)00078-6     Document Type: Article

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