Structures along the catalytic pathway of PrmC/HemK, an N5-glutamine AdoMet-dependent methyltransferase

Biochemistry

Volumn 42, Issue 19, 2003, Pages 5592-5599

  Schubert, Heidi L ^a   Phillips, John D ^a   Hill, Christopher P ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CARRIER CONCENTRATION; CONFORMATIONS; CRYSTAL STRUCTURE; HYDROGEN BONDS; PROTEINS; SUBSTRATES;

NUCLEOPHILES;

BIOCHEMISTRY;

GLUTAMINE; GLUTAMINE DERIVATIVE; METHYLTRANSFERASE; PROTEIN HEMK; PROTEIN PRMC; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; ENZYME STRUCTURE; HYDROGEN BOND; METHYLATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN SYNTHESIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CATALYTIC DOMAIN; ELECTROSTATICS; ESCHERICHIA COLI PROTEINS; GENES, BACTERIAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; PROTEIN METHYLTRANSFERASES; SEQUENCE HOMOLOGY, AMINO ACID; THERMOTOGA MARITIMA;

EID: 0038629269     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034026p     Document Type: Article

References (42)

1. Gary, J. D., and Clarke, S. (1998) Proc. Natl. Acad. Sci. U.S.A. 61, 65-131.
2. Levit, M. N., and Stock, J. B. (2002) J. Biol. Chem. 15, 15.
3. Klotz, A. V., and Glazer, A. N. (1987) J. Biol. Chem. 262, 17350-17355.
4. Najbauer, J., Orpiszewski, J., and Aswad, D. W. (1996) Biochemistry 35, 5183-5190.
5. Lachner, M., and Jenuwein, T. (2002) Curr. Opin. Cell Biol. 14, 286-298.
6. Dincbas-Renqvist, V., Engstrom, A., Mora, L., Heurgue-Hamard, V., Buckingham, R., and Ehrenberg, M. (2000) EMBO J. 19, 6900-6907.
7. Heurgue-Hamard, V., Champ, S., Engstrom, A., Ehrenberg, M., and Buckingham, R. H. (2002) EMBO J. 21, 769-778.
8. Kisselev, L. L., and Buckingham, R. H. (2000) Trends Biochem. Sci. 25, 561-566.
9. Ehrenberg, M., and Tenson, T. (2002) Nat. Struct. Biol. 9, 85-87.
10. Song, H., Mugnier, P., Das, A. K., Webb, H. M., Evans, D. R., Tuite, M. F., Hemmings, B. A., and Barford, D. (2000) Cell 100, 311-321.
11. Frolova, L. Y., Tsivkovskii, R. Y., Sivolobova, G. F., Oparina, N. Y., Serpinsky, O. I., Blinov, V. M., Tatkov, S. I., and Kisselev, L. L. (1999) RNA 5, 1014-1020.
12. Nakahigashi, K., Kubo, N., Narita, S., Shimaoka, T., Goto, S., Oshima, T., Mori, H., Maeda, M., Wada, C., and Inokuchi, H. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 1473-1478.
13. Clarke, S. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 1104-1106.
14. Nakayashiki, T., Nishimura, K., and Inokuchi, H. (1995) Gene 153, 67-70.
15. Fauman, E. B., Blumenthal, R. M., and Cheng, X. (1999) in S-Adenosylmethionine-dependent Methyltransferases: Structures and Functions (Cheng, X., and Blumenthal, R. M., Eds.) pp 3-38, World Scientific Publishing, River Edge, NJ.
16. Martin, J. L., and McMillian, F. M. (2002) Curr. Opin. Struct. Biol. 12, 783-793.
17. Malone, T., Blumenthal, R. M., and Cheng, X. (1995) J. Mol. Biol. 253, 618-632.
18. Goedecke, K., Pignot, M., Goody, R. S., Scheidig, A. J., and Weinhold, E. (2001) Nat. Struct. Biol. 8, 121-125.
19. Newby, Z. E., Lau, E. Y., and Bruice, T. C. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 7922-7927.
20. Sheffield, P., Gerrard, S., and Derewenda, Z. (1999) Protein Exp. Purifi. 15, 34-39.
21. Van Duyne, G. D., Standaert, R. F., Karplus, P. A., Schreiber, S. L., and Clardy, J. (1993) J. Mol. Biol. 229, 105-124.
22. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 267, 307-326.
23. Terwilliger, T. C. (2001) Acta Crystallogr. D, Biol. Crystallogr. 57, 1763-1775.
24. Terwilliger, T. C. (2001) Acta Crystallogr. D, Biol. Crystallogr. 57, 1755-1762.
25. Jones, A. T., Zou, J.-Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. D, Biol. Crystallogr. A47, 110-119.
26. Murshudov, G. N., and Dodson, E. J. (1997) Acta Crystallogr. D, Biol. Crystallogr. 53, 240-255.
27. Acta Crystallogr. (1994) D50, 760-763.
28. Holm, L., and Sander, C. (1993) J. Mol. Biol. 223, 123-138.
29. Bujnicki, J. M., and Rychlewski, L. (2002) BMC Bioinformatics 3, 10.
30. Klimasauskas, S., Kumar, S., Roberts, R. J., and Cheng, X. (1994) Cell 76, 357-369.
31. Bujnicki, J. M., and Radlinska, M. (1999) IUBMB Life 48, 247-249.
32. Milner-White, E. J. (1997) Protein Sci. 6, 2477-2482.
33. Wu, J. C., and Santi, D. V. (1987) J. Biol. Chem. 262, 4778- 4786.
34. Lau, E. Y., and Bruice, T. C. (1999) J. Mol. Biol. 293, 9-18.
35. Vidgren, J., Svensson, L. A., and Liljas, A. (1994) Nature 368, 354-357.
36. Zheng, Y.-J., and Bruice, T. C. (1997) J. Am. Chem. Soc. 119, 8137-8145.
37. Djordjevic, S., and Stock, A. M. (1997) Structure 5, 545-558.
38. Zhang, X., Zhou, L., and Cheng, X. (2000) EMBO J. 19, 3509- 3519.
39. Vestergaard, B., Van, L. B., Andersen, G. R., Nyborg, J., Buckingham, R. H., and Kjeldgaard, M. (2001) Mol. Cell 8, 1375-1382.
40. DeLano, W. L. (2002) http://www/pymol.org.
41. Schluckebier, G., Kozak, M., Bleimling, N., Weinhold, E., and Saenger, W. (1997) J. Mol. Biol. 265, 56-67.
42. Nicholls, A., Sharp, K. A., and Honig, B. (1991) Proteins 11, 281-296.