Clinical experience with open-label topiramate use in infants younger than 2 years of age

Journal of Child Neurology

Volumn 18, Issue 4, 2003, Pages 258-262

  Watemberg, Nathan ^a   Goldberg Stern, Hadassah ^b   Ben Zeev, Bruria ^c   Berger, Itai ^e   Straussberg, Rachel ^b   Kivity, Sara ^b   Kramer, Uri ^d   Brand, Nathan ^c   Lerman Sagie, Tally ^a  

^a WOLFSON MEDICAL CENTER   (Israel)

^b Schneider Children Hospital   (Israel)

^c SHEBA MEDICAL CENTER   (Israel)

^d TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^e HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CLOBAZAM; CLONAZEPAM; LAMOTRIGINE; MIDAZOLAM; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PYRIDOXINE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN;

ABSENCE; ANOREXIA; ANTICONVULSANT THERAPY; CLINICAL ARTICLE; COMPLEX PARTIAL SEIZURE; DROWSINESS; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; EPILEPSY; EXPERIENCE; HUMAN; INFANT; INFANTILE SPASM; IRRITABILITY; KETOGENIC DIET; MEDICAL RECORD; MONOTHERAPY; MYOCLONUS EPILEPSY; ONSET AGE; OPEN STUDY; PRESCHOOL CHILD; PRESCRIPTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; REVIEW; SIMPLE PARTIAL SEIZURE; TONIC SEIZURE; TREATMENT OUTCOME; WEIGHT REDUCTION;

EID: 0038628025     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/08830738030180040901     Document Type: Review

References (27)

1. Faught E, Wilder BJ, Ramsay RE, et al: Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 200, 400, and 600 mg daily doses: Topiramate YD Study Group. Neurology 1996;46:1684-1690.
2. Ben-Menachem E, Henriksen O, Dam M, et al: Double blind, placebo-controlled trial of topiramate as add-on therapy in patients with refractory partial seizures. Epilepsia 1996;37:539-543.
3. Biton V, Montouris GD, Ritter FJ, et al: A randomized, placebo-controlled study of topiramate in primary generalized tonic-clonic seizures. Topiramate YTC Study Group. Neurology 1999; 53:1330-1337.
4. Elterman R, Glauser TA, Wyllie E, et al, and the Topiramate YP Study Group: A double blind, randomized trial of topiramate as adjunctive therapy for partial-onset seizures in children. Neurology 1999;52:1338-1344.
5. Sadcheo RC, Glauser TA, Ritter F, et al: A double blind, randomized trial of topiramate in Lennox-Gastaut syndrome. Topiramate YL Study Group. Neurology 1999;52:1882-1887.
6. Glauser TA, Clark PO, McGee K: Long-term response to topiramate in the treatment of infantile spasms. Epilepsia 2000;41:S91-S94.
7. Herranz JL: Topiramate: A broad spectrum antiepileptic drug, used in 224 patients with refractory epilepsy. Rev Neurol 2000;31:822-828.
8. Uldall P, Buchholt JM: Clinical experiences with topiramate in children with intractable epilepsy. Eur J Paediatr Neurol 1999;3:105-111.
9. Coppola G, Caliendo G, Terracciano MM, et al: Topiramate in refractory partial-onset seizures in children, adolescents and young adults: A multicenter open trial. Epilepsy Res 2001;43:255-260.
10. Thijs J, Verhelst H, Van Coster R: Retrospective study of topiramate in a paediatric population with intractable epilepsy showing promising effects in the West syndrome patients. Acta Neurol Belg 2001;101:171-176.
11. Physician leaflet on topiramate. Geneva, Janssen-Cilag Pharmaceuticals, 2001.
12. Ritter F, Glauser TA, Elterman RD, Wyllie E, and the Topiramate YP Study Group: Effectiveness, tolerability, and safety of topiramate in children with partial-onset seizures. Epilepsia 2000;41(Suppl 1)S82-S85.
13. Wheless JW: Use of topiramate in childhood generalized seizure disorders. J Child Neurol 2000;15(Suppl 1):S7-S13.
14. Glauser TA, Clark PO, Strawsburg R: A pilot study of topiramate in the treatment of infantile spasms. Epilepsia 1998-139:1324-1328.
15. Wong M, Trevathan E: Infantile spasms. Pediatr Neurol 2001;24:89-98.
16. Kugler SL, Sachdeo RC: Topiramate efficacy in infancy. Pediatr Neurol 1998;19:320-322.
17. Capovilla V, Vigevano F: Benign idiopathic partial epilepsies in infancy. J Child Neurol 2001;16:874-881.
18. Deckers CL, Czuczwar SJ, Hekster YA, et al: Selection of antiepileptic drug polytherapy based on mechanisms of action: The evidence reviewed. Epilepsia 2000;41:1364-1374.
19. Thompson PJ, Baxendale SA, Duncan JS, Sander JW: Effects of topiramate on cognitive function. J Neurol Neurosurg Psychiatry 2000;69:636-641.
20. Tatum WO, French JA, Faught GL, et al: Postmarketing experience with topiramate and cognition. Epilepsia 2001;42:1134-1140.
21. Gerber PE, Hamiwka L, Connolly MB, Farrell K: Factors associated with behavioral and cognitive abnormalities in children receiving topiramate. Pediatr Neurol 2000;22:200-203.
22. Levisohn PM: Safety and tolerability of topiramate in children. J Child Neurol 2000;15(Suppl 1):S22-S26.
23. Abou-Khalil B and the Topiramate YOL Study Group: Topiramate in the long-term management of refractory epilepsy. Epilepsia 2000;41(Suppl 1):S72-S76.
24. Reife R, Pledger G, Wu SC: Topiramate as add-on therapy: Pooled analysis of randomized controlled trials in adults. Epilepsia 2000;41(Suppl 1):S66-S71.
25. Montouris GD, Biton V, Rosenfeld WE, and the Topiramate YTC/YTCE Study Group: Nonfocal generalized tonic-clonic seizures: Response during long-term topiramate treatment. Epilepsia 2000-141(Suppl 1):S77-S81.
26. Genton P: When antiepileptic drugs aggravate epilepsy. Brain Dev 2000;22:75-80.
27. Perucca E, Gram L, Avanzini G, Dulac O: Antiepileptic drugs as a cause of worsening seizures. Epilepsia 1998;39:5-17.