-
1
-
-
0035811050
-
Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments
-
Alonso A. D., Zaidi T., Novak, M., Grundke-Iqbal I., and Iqbal K. (2001a) Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments. Proc. Natl. Acad. Sci. USA 98, 6923-6928.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6923-6928
-
-
Alonso, A.D.1
Zaidi, T.2
Novak, M.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
2
-
-
0035851157
-
Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease-like protein
-
Alonso A. D., Zaidi T., Novak, M., Barra H. S., Grundke-Iqbal I., and Iqbal K. (2001b) Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease-like protein. J. Biol. Chem. 276, 37,967-37,973.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37967-37973
-
-
Alonso, A.D.1
Zaidi, T.2
Novak, M.3
Barra, H.S.4
Grundke-Iqbal, I.5
Iqbal, K.6
-
3
-
-
0026030994
-
Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer's disease
-
Bancher C., Grundke-Iqbal I., Iqbal K., Fried V. A., Smith H. T., and Wisniewski H. M. (1991) Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer's disease. Brain Res. 539, 11-18.
-
(1991)
Brain Res.
, vol.539
, pp. 11-18
-
-
Bancher, C.1
Grundke-Iqbal, I.2
Iqbal, K.3
Fried, V.A.4
Smith, H.T.5
Wisniewski, H.M.6
-
4
-
-
0037029740
-
Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25-transgenic mice
-
Bian F., Nath R., Sobocinski G., et al. (2002) Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25-transgenic mice. J. Comp. Neurol. 446, 257-266.
-
(2002)
J. Comp. Neurol.
, vol.446
, pp. 257-266
-
-
Bian, F.1
Nath, R.2
Sobocinski, G.3
-
5
-
-
0027468235
-
Neuropathological indexes of Alzheimer's disease in demented and nondemented persons aged 80 years and older
-
Berg L., McKeel D. W., Miller J. P., Baty J., and Morris J. C. (1993) Neuropathological indexes of Alzheimer's disease in demented and nondemented persons aged 80 years and older. Arch. Neurol. 50, 349-358.
-
(1993)
Arch. Neurol.
, vol.50
, pp. 349-358
-
-
Berg, L.1
McKeel, D.W.2
Miller, J.P.3
Baty, J.4
Morris, J.C.5
-
6
-
-
0028362458
-
A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
-
Braak E., Braak H., and Mandelkow E. M. (1994) A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol. 87, 554-567.
-
(1994)
Acta Neuropathol.
, vol.87
, pp. 554-567
-
-
Braak, E.1
Braak, H.2
Mandelkow, E.M.3
-
7
-
-
0344859874
-
Phosphorylated serine422 on tau proteins is a pathological epitope found in several diseases with neurofibrillary degeneration
-
Bussiere T., Hof P. R., Mailliot C., et al. (1999) Phosphorylated serine422 on tau proteins is a pathological epitope found in several diseases with neurofibrillary degeneration. Acta Neuropathol. 97, 221-230.
-
(1999)
Acta Neuropathol.
, vol.97
, pp. 221-230
-
-
Bussiere, T.1
Hof, P.R.2
Mailliot, C.3
-
8
-
-
0027410176
-
Beta A4 deposits are constant in the brain of the oldest old: An immunocytochemical study of 20 French centenarians
-
Delaere P., He Y., Fayet G., Duyckaerts C., and Hauw J. J. (1993) Beta A4 deposits are constant in the brain of the oldest old: an immunocytochemical study of 20 French centenarians. Neurobiol. Aging 14, 191-194.
-
(1993)
Neurobiol. Aging
, vol.14
, pp. 191-194
-
-
Delaere, P.1
He, Y.2
Fayet, G.3
Duyckaerts, C.4
Hauw, J.J.5
-
9
-
-
0026549985
-
Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state
-
Drewes G., Lichtenberg-Kraag B., Doring F., et al. (1992) Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state. EMBO J. 11, 2131-2138.
-
(1992)
EMBO J.
, vol.11
, pp. 2131-2138
-
-
Drewes, G.1
Lichtenberg-Kraag, B.2
Doring, F.3
-
10
-
-
0034329543
-
Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants
-
Flaherty D. B., Soria J. P., Tomasiewicz H. G., and Wood J. G. (2000) Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants. J. Neurosci. Res. 62, 463-472.
-
(2000)
J. Neurosci. Res.
, vol.62
, pp. 463-472
-
-
Flaherty, D.B.1
Soria, J.P.2
Tomasiewicz, H.G.3
Wood, J.G.4
-
11
-
-
0028173238
-
Tau phosphorylation in human, primate, and rat brain: Evidence that a pool of tau is highly phosphorylated in vivo and is rapidly dephosphorylated in vitro
-
Garver T. D., Harris K. A., Lehman R. A., Lee V. M. Y., Trojanowski J. Q., and Billingsley M. L. (1994) Tau phosphorylation in human, primate, and rat brain: evidence that a pool of tau is highly phosphorylated in vivo and is rapidly dephosphorylated in vitro. J. Neurochem. 63, 2279-2287.
-
(1994)
J. Neurochem.
, vol.63
, pp. 2279-2287
-
-
Garver, T.D.1
Harris, K.A.2
Lehman, R.A.3
Lee, V.M.Y.4
Trojanowski, J.Q.5
Billingsley, M.L.6
-
12
-
-
0030963035
-
Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases
-
Goedert M., Hasegawa M., Jakes R., Lawler S., Cuenda A., and Cohen P. (1997) Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases. FEBS Lett. 409, 57-62.
-
(1997)
FEBS Lett.
, vol.409
, pp. 57-62
-
-
Goedert, M.1
Hasegawa, M.2
Jakes, R.3
Lawler, S.4
Cuenda, A.5
Cohen, P.6
-
13
-
-
0034472890
-
Metabolically active rat brain slices as a model to study the regulation of protein phosphorylation in mammalian brain
-
Gong C. X., Lidsky T., Wegiel J., Grundke-Iqbal I., and Iqbal K. (2001) Metabolically active rat brain slices as a model to study the regulation of protein phosphorylation in mammalian brain. Brain Res. Brain Res. Protoc. 6, 134-140.
-
(2001)
Brain Res. Brain Res. Protoc.
, vol.6
, pp. 134-140
-
-
Gong, C.X.1
Lidsky, T.2
Wegiel, J.3
Grundke-Iqbal, I.4
Iqbal, K.5
-
14
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
Grundke-Iqbal I., Iqbal K., Tung Y. C., Quinlan M., Wisniewski H. M., and Binder L. I. (1986) Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. USA 83, 4913-4917.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
15
-
-
0026487365
-
Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase
-
Hanger D. P., Hughes K., Woodgett J. R., Brion J. P., and Anderton B. H. (1992) Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci. Lett. 147, 58-62.
-
(1992)
Neurosci. Lett.
, vol.147
, pp. 58-62
-
-
Hanger, D.P.1
Hughes, K.2
Woodgett, J.R.3
Brion, J.P.4
Anderton, B.H.5
-
16
-
-
0029879046
-
Characterisation of mAb AP422, a novel phosphorylation-dependent antibody against tau protein
-
Hasegawa M., Jakes R., Crowther R. A., Lee V. M. Y., Ihara Y., and Goedert M. (1996) Characterisation of mAb AP422, a novel phosphorylation-dependent antibody against tau protein. FEBS Lett. 384, 25-30.
-
(1996)
FEBS Lett.
, vol.384
, pp. 25-30
-
-
Hasegawa, M.1
Jakes, R.2
Crowther, R.A.3
Lee, V.M.Y.4
Ihara, Y.5
Goedert, M.6
-
17
-
-
0030611097
-
Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse
-
Irizarry M. C., Soriano F., McNamara M., Page K. J., Schenk D., Games D., and Hyman B. T. (1997) Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse. J. Neurosci. 17, 7053-7059.
-
(1997)
J. Neurosci.
, vol.17
, pp. 7053-7059
-
-
Irizarry, M.C.1
Soriano, F.2
McNamara, M.3
Page, K.J.4
Schenk, D.5
Games, D.6
Hyman, B.T.7
-
19
-
-
0034426011
-
Neurofibrillary tangles, amyotrophy, and progressive motor disturbance in mice expressing mutant (P301L) tau protein
-
Lewis J., McGowan E., Rockwood J., et al. (2000) Neurofibrillary tangles, amyotrophy, and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet. 25, 402-405.
-
(2000)
Nat. Genet.
, vol.25
, pp. 402-405
-
-
Lewis, J.1
McGowan, E.2
Rockwood, J.3
-
20
-
-
0028675873
-
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells
-
Lovestone S., Reynolds C. H., Latimer D., et al. (1994) Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Curr. Biol. 4, 1077-1086.
-
(1994)
Curr. Biol.
, vol.4
, pp. 1077-1086
-
-
Lovestone, S.1
Reynolds, C.H.2
Latimer, D.3
-
21
-
-
0035863188
-
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
-
Lucas J. J., Hernandez F., Gomez-Ramos P., Moran M. A., Hen R., and Avila J. (2001) Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J. 20, 27-39.
-
(2001)
EMBO J.
, vol.20
, pp. 27-39
-
-
Lucas, J.J.1
Hernandez, F.2
Gomez-Ramos, P.3
Moran, M.A.4
Hen, R.5
Avila, J.6
-
22
-
-
0032500861
-
Alzheimer-specific epitope of AT100 in transfected cell lines with tau: Toward an efficient cell model of tau abnormal phosphorylation
-
Mailliot C., Bussiere T., Caillet-Boudin M. L., Delacourte A., and Buee L. (1998) Alzheimer-specific epitope of AT100 in transfected cell lines with tau: toward an efficient cell model of tau abnormal phosphorylation. Neurosci. Lett. 255, 13-16.
-
(1998)
Neurosci. Lett.
, vol.255
, pp. 13-16
-
-
Mailliot, C.1
Bussiere, T.2
Caillet-Boudin, M.L.3
Delacourte, A.4
Buee, L.5
-
23
-
-
0026619584
-
Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau
-
Mandelkow E. M., Drewes G., Biernat J., Gustke N., Van Lint J., Vandenheede J. R., and Mandelkow E. (1992) Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau. FEBS Lett. 314, 315-321.
-
(1992)
FEBS Lett.
, vol.314
, pp. 315-321
-
-
Mandelkow, E.M.1
Drewes, G.2
Biernat, J.3
Gustke, N.4
Van Lint, J.5
Vandenheede, J.R.6
Mandelkow, E.7
-
24
-
-
0027945346
-
Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau
-
Matsuo E. S., Shin R. W., Billingsley M. L., Van deVoorde A., O'Connor M., Trojanowski J. Q., and Lee V. M. Y. (1994) Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau. Neuron 13, 989-1002.
-
(1994)
Neuron
, vol.13
, pp. 989-1002
-
-
Matsuo, E.S.1
Shin, R.W.2
Billingsley, M.L.3
Van DeVoorde, A.4
O'Connor, M.5
Trojanowski, J.Q.6
Lee, V.M.Y.7
-
25
-
-
0032502829
-
Characterization of tau phosphorylation in glycogen synthase kinase-3beta and cyclin dependent kinase-5 activator (p23) transfected cells
-
Michel G., Mercken M., Murayama M., Noguchi K., Ishiguro K., Imahori K., and Takashima A. (1998) Characterization of tau phosphorylation in glycogen synthase kinase-3beta and cyclin dependent kinase-5 activator (p23) transfected cells. Biochim. Biophys. Acta 1380, 177-182.
-
(1998)
Biochim. Biophys. Acta
, vol.1380
, pp. 177-182
-
-
Michel, G.1
Mercken, M.2
Murayama, M.3
Noguchi, K.4
Ishiguro, K.5
Imahori, K.6
Takashima, A.7
-
26
-
-
0027421625
-
Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments
-
Paudel H. K., Lew J., Ali Z., and Wang J. H. (1993) Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments. J. Biol. Chem. 268, 23,512-23,518.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 23512-23518
-
-
Paudel, H.K.1
Lew, J.2
Ali, Z.3
Wang, J.H.4
-
27
-
-
0025719976
-
Two novel kinases phosphorylate tau and the KSP site of heavy neurofilament subunits in high stoichiometric ratios
-
Roder H. M. and Ingram V. M. (1991) Two novel kinases phosphorylate tau and the KSP site of heavy neurofilament subunits in high stoichiometric ratios. J. Neurosci. 11, 3325-3343.
-
(1991)
J. Neurosci.
, vol.11
, pp. 3325-3343
-
-
Roder, H.M.1
Ingram, V.M.2
-
28
-
-
0027181221
-
Brain protein kinase PK40erk converts TAU into a PHF-like form as found in Alzheimer's disease
-
Roder H. M., Eden P. A., and Ingram V. M. (1993) Brain protein kinase PK40erk converts TAU into a PHF-like form as found in Alzheimer's disease. Biochem. Biophys. Res. Commun. 193, 639-647.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.193
, pp. 639-647
-
-
Roder, H.M.1
Eden, P.A.2
Ingram, V.M.3
-
29
-
-
0028927602
-
Phosphatase resistance of ERK2 brain kinase PK40erk2
-
Roder H. M., Hoffman F. J., and Schröder W. (1995) Phosphatase resistance of ERK2 brain kinase PK40erk2. J. Neurochem. 64, 2203-2212.
-
(1995)
J. Neurochem.
, vol.64
, pp. 2203-2212
-
-
Roder, H.M.1
Hoffman, F.J.2
Schröder, W.3
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