메뉴 건너뛰기




Volumn 22, Issue 3, 2003, Pages 399-409

Pharmaceuticals and personal care products in the environment: Regulatory drivers and research needs

Author keywords

Pharmaceuticals and personal care products; QSARs; Regulatory drivers; Research needs

Indexed keywords

BIOMEDICAL EQUIPMENT; COMPUTATIONAL CHEMISTRY; ENVIRONMENTAL PROTECTION AGENCY; RISK ASSESSMENT;

EID: 0038515078     PISSN: 1611020X     EISSN: None     Source Type: Journal    
DOI: 10.1002/qsar.200390030     Document Type: Conference Paper
Times cited : (63)

References (63)
  • 2
    • 0034672012 scopus 로고    scopus 로고
    • Monitoring natural and synthetic estrogens at activated sludge sewage treatment plants and in a receiving river water
    • Baronti, C., Curini R., D'Ascenzo, G., Di Corcia, A., Gentili, A., and Samperi, R., Monitoring Natural and Synthetic Estrogens at Activated Sludge Sewage Treatment Plants and in a Receiving River Water, Environ. Sci. Technol. 34, 5059-5066 (2000).
    • (2000) Environ. Sci. Technol. , vol.34 , pp. 5059-5066
    • Baronti, C.1    Curini, R.2    D'Ascenzo, G.3    Di Corcia, A.4    Gentili, A.5    Samperi, R.6
  • 3
    • 0032100629 scopus 로고    scopus 로고
    • Identification of estrogenic chemicals in STW effluent. 2. In vivo responses in trout and roach
    • Routledge, E. J., Sheahan, D., Desbrow, C., Sumpter, J. P., and Waldock, M., Identification of Estrogenic Chemicals in STW Effluent. 2. In Vivo Responses in trout and Roach, Environ. Sci. Technol. 32, 1559-1565 (1998).
    • (1998) Environ. Sci. Technol. , vol.32 , pp. 1559-1565
    • Routledge, E.J.1    Sheahan, D.2    Desbrow, C.3    Sumpter, J.P.4    Waldock, M.5
  • 4
    • 0027300955 scopus 로고
    • The potential for avermectins to affect wildlife
    • McCracken, D. I., The Potential for Avermectins to Affect Wildlife, Vet. Parasitol. 48, 273-280 (1993).
    • (1993) Vet. Parasitol. , vol.48 , pp. 273-280
    • McCracken, D.I.1
  • 5
    • 0030851571 scopus 로고    scopus 로고
    • Behavior of pharmaceutical drugs (human and animal health) in the environment
    • Velagaleti, R., Behavior of Pharmaceutical Drugs (Human and Animal Health) in the Environment, Drug. Inform J. 31, 715-722 (1997).
    • (1997) Drug. Inform J. , vol.31 , pp. 715-722
    • Velagaleti, R.1
  • 6
    • 0032210734 scopus 로고    scopus 로고
    • Occurrence of drugs in German sewage treatment plants and rivers
    • Ternes, T. A., Occurrence of Drugs in German Sewage Treatment Plants and Rivers, Water Res. 31(11), 3245-3260 (1998).
    • (1998) Water Res. , vol.31 , Issue.11 , pp. 3245-3260
    • Ternes, T.A.1
  • 7
    • 0343338129 scopus 로고    scopus 로고
    • Sources behaviour and fate of organic contaminants during sewage treatment and in sewage sludges
    • Rogers, H. R., Sources Behaviour and Fate of Organic Contaminants During Sewage Treatment and in Sewage Sludges, Sci. Total Environ. 185, 3-26 (1996).
    • (1996) Sci. Total Environ. , vol.185 , pp. 3-26
    • Rogers, H.R.1
  • 8
    • 0033383635 scopus 로고    scopus 로고
    • Pharmaceuticals and personal care products in the environment: Agents of subtle change?
    • Daughton, C. G., and Ternes, T. A., Pharmaceuticals and Personal Care Products in the Environment: Agents of Subtle Change?, Environ. Health Perspect. 107(Supplement 6), 907-938 (1999).
    • (1999) Environ. Health Perspect. , vol.107 , Issue.SUPPL. 6 , pp. 907-938
    • Daughton, C.G.1    Ternes, T.A.2
  • 10
    • 0035417251 scopus 로고    scopus 로고
    • Determination of endocrine-disrupting phenolic compounds and estrogens in surface and drinking water by HRGC-(NCI)-MS in the picogram per liter range
    • Kuch, H. M., and Ballschmiter K., Determination of Endocrine-Disrupting Phenolic Compounds and Estrogens in Surface and Drinking Water by HRGC-(NCI)-MS in the Picogram per Liter Range, Environ. Sci. Technol. 35, 3201-3206 (2001).
    • (2001) Environ. Sci. Technol. , vol.35 , pp. 3201-3206
    • Kuch, H.M.1    Ballschmiter, K.2
  • 11
    • 0032807198 scopus 로고    scopus 로고
    • Biodegradability of cefotiam, ciprofloxacin, meropenem, penicillin G., and sulfametohoxazole and inhibition of wastewater bacteria
    • Al-Ahmad, A., Daschner, F. D., and Kummerer, K., Biodegradability of Cefotiam, Ciprofloxacin, Meropenem, Penicillin G., and Sulfametohoxazole and Inhibition of Wastewater Bacteria, Arch. Environ. Contam. Toxicol. 37, 158-153 (1999).
    • (1999) Arch. Environ. Contam. Toxicol. , vol.37 , pp. 158-153
    • Al-Ahmad, A.1    Daschner, F.D.2    Kummerer, K.3
  • 13
    • 0037052860 scopus 로고    scopus 로고
    • The sorption and transport of a sulfonamide antibiotic in soil systems
    • Boxall, A. B. A., Blackwell, P. A., Cavello, R., Kay, P., and Tolls, J., The Sorption and Transport of a Sulfonamide Antibiotic in Soil Systems, Toxicol. Lett. 131, 19-28 (2002).
    • (2002) Toxicol. Lett. , vol.131 , pp. 19-28
    • Boxall, A.B.A.1    Blackwell, P.A.2    Cavello, R.3    Kay, P.4    Tolls, J.5
  • 14
    • 0019431652 scopus 로고
    • Identification of musk xylene and musk ketone in freshwater fish collected from the Tama River, Tokyo
    • Yamagishi, T., Miyazaki, T., Horii, S., and Kaneko, S., Identification of Musk Xylene and Musk Ketone in Freshwater Fish Collected from the Tama River, Tokyo, Bull. Environ. Contam. Toxicol. 26, 656-662. (1981).
    • (1981) Bull. Environ. Contam. Toxicol. , vol.26 , pp. 656-662
    • Yamagishi, T.1    Miyazaki, T.2    Horii, S.3    Kaneko, S.4
  • 15
    • 0032533389 scopus 로고    scopus 로고
    • Occurrence and fate of the pharmaceutical drug dichlofenac in surface waters: Rapid photodegradation in a lake
    • Buser H-R., Poiger, T., and Müller, M. D., Occurrence and Fate of the Pharmaceutical Drug Dichlofenac in Surface Waters: Rapid Photodegradation in a Lake, Environ. Sci. Technol. 32, 3449-3456 (1998).
    • (1998) Environ. Sci. Technol. , vol.32 , pp. 3449-3456
    • Buser, H.-R.1    Poiger, T.2    Müller, M.D.3
  • 16
    • 0031935383 scopus 로고    scopus 로고
    • Identification of fluoroquinolone antibiotics as the main source of umuc genotoxicity in native hospital wastewater
    • Hartmann A., Alder, A. C., Koller, T., and Widmer, R. M., Identification of Fluoroquinolone Antibiotics as the Main Source of umuC Genotoxicity in Native Hospital Wastewater, Environ. Toxicol. Chem. 17(3), 377-382 (1998).
    • (1998) Environ. Toxicol. Chem. , vol.17 , Issue.3 , pp. 377-382
    • Hartmann, A.1    Alder, A.C.2    Koller, T.3    Widmer, R.M.4
  • 17
    • 0001743761 scopus 로고    scopus 로고
    • Simultaneous determination of antiseptics and acidic drugs in sewage and river
    • Ternes, T. A., Stumpf, M., Schuppert, B., and Haberer, K., Simultaneous Determination of Antiseptics and Acidic Drugs in Sewage and River, Vom. Wasser 90, 295-309 (1998).
    • (1998) Vom. Wasser , vol.90 , pp. 295-309
    • Ternes, T.A.1    Stumpf, M.2    Schuppert, B.3    Haberer, K.4
  • 18
    • 0001337851 scopus 로고    scopus 로고
    • Determination of drugs in sewage treatment plants and river water
    • Stumpf, M., Ternes, T. A., Haberer, K., Seel, P., and Baumann, W., Determination of Drugs in Sewage Treatment Plants and River Water, Vom Wasser 86, 291-303 (1996).
    • (1996) Vom. Wasser , vol.86 , pp. 291-303
    • Stumpf, M.1    Ternes, T.A.2    Haberer, K.3    Seel, P.4    Baumann, W.5
  • 19
    • 0042548456 scopus 로고    scopus 로고
    • Biodegradability of the anti-tumor agent ifosamide and its occurrence in hospital effluents and communal sewage
    • Kümmerer, K., Steger-Hartmann, T., and Meyer, M., Biodegradability of the Anti-Tumor Agent Ifosamide and Its Occurrence in Hospital Effluents and Communal Sewage, Water Res. 31 (11), 2705-2710 (1997).
    • (1997) Water Res. , vol.31 , Issue.11 , pp. 2705-2710
    • Kümmerer, K.1    Steger-Hartmann, T.2    Meyer, M.3
  • 20
    • 0034789817 scopus 로고    scopus 로고
    • Drugs in the environment: Emission of drugs, diagnostic aids and disinfectants into waste by hospitals in relation to other sources - A review
    • Kümmerer K., Drugs in the Environment: Emission of Drugs, Diagnostic Aids and Disinfectants Into Waste by Hospitals in Relation to Other Sources - A Review, Chemosphere 45, 957-969 (2001).
    • (2001) Chemosphere , vol.45 , pp. 957-969
    • Kümmerer, K.1
  • 21
    • 0037085574 scopus 로고    scopus 로고
    • Pharmaceuticals, hormones, and other organic wasterwater contaminants in US streams, 1999-2000: A national reconnaissance
    • Kolpin, D. W., Furlong, E., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B. and Buxton, H. T., Pharmaceuticals, Hormones, and Other Organic Wasterwater Contaminants in US Streams, 1999-2000: A National Reconnaissance, Environ. Sci. Technol 36, 1202-1211 (2002).
    • (2002) Environ. Sci. Technol. , vol.36 , pp. 1202-1211
    • Kolpin, D.W.1    Furlong, E.2    Meyer, M.T.3    Thurman, E.M.4    Zaugg, S.D.5    Barber, L.B.6    Buxton, H.T.7
  • 23
    • 0028988626 scopus 로고
    • Occurrence and distribution of pharmaceutical organic compounds in the groundwater downgradient of a landfill (Grindsted, Denmark)
    • Holm, J. V., Rügge, K., Bjerg, P. L., and Christensen, T. H., Occurrence and Distribution of Pharmaceutical Organic Compounds in the Groundwater Downgradient of a Landfill (Grindsted, Denmark), Environ. Sci. Technol. 29(5), 1415-1420 (1995).
    • (1995) Environ. Sci. Technol. , vol.29 , Issue.5 , pp. 1415-1420
    • Holm, J.V.1    Rügge, K.2    Bjerg, P.L.3    Christensen, T.H.4
  • 24
    • 85192671881 scopus 로고
    • Synthetic nitro musk fragrances and bromocyclen - New environmental chemicals in fish and mussels as well as in breast milk and human lipids
    • Geyer H. J., Rimkus, G., Wolf, M., Attar, A., Steinburg, C., and Kettrup, A., Synthetic Nitro Musk Fragrances and Bromocyclen - New Environmental Chemicals in Fish and Mussels as Well as in Breast Milk and Human Lipids, Z. Umweltchem Ökotox 61(1), 8-17 (1994).
    • (1994) Z. Umweltchem Ökotox , vol.61 , Issue.1 , pp. 8-17
    • Geyer, H.J.1    Rimkus, G.2    Wolf, M.3    Attar, A.4    Steinburg, C.5    Kettrup, A.6
  • 25
    • 0024397675 scopus 로고
    • The environmental impact of the use of ivermectin: Environmental effects and fate
    • Halley, B. A., Jacob, T. A., and Lu, A. Y. H., The Environmental Impact of the Use of Ivermectin: Environmental Effects and Fate, Chemosphere 18: 1543-1563 (1989).
    • (1989) Chemosphere , vol.18 , pp. 1543-1563
    • Halley, B.A.1    Jacob, T.A.2    Lu, A.Y.H.3
  • 26
    • 0027217578 scopus 로고
    • Environmental assessment of avermectins by the U.S. food and drug administration
    • Bloom, R. A., and Matheson III, J. C., Environmental Assessment of Avermectins by the U.S. Food and Drug Administration, Vet. Parasitol. 48, 281-294 (1993).
    • (1993) Vet. Parasitol. , vol.48 , pp. 281-294
    • Bloom, R.A.1    Matheson J.C. III2
  • 27
    • 0035986253 scopus 로고    scopus 로고
    • Comparison of two screening level risk assessment approaches for six disinfectants and pharmaceuticals
    • van Wezel, A. P., and Jager, T., Comparison of Two Screening Level Risk Assessment Approaches for Six Disinfectants and Pharmaceuticals, Chemosphere 47, 1113-1128 (2002).
    • (2002) Chemosphere , vol.47 , pp. 1113-1128
    • Van Wezel, A.P.1    Jager, T.2
  • 35
    • 0031774853 scopus 로고    scopus 로고
    • US food and drug administration ecological risk assessments for drugs used in aquaculture and in terrestrial animals
    • Haley, C. J., Eirkson, C., Geil, S., and Mahanes,.B., US Food and Drug Administration Ecological Risk Assessments for Drugs Used in Aquaculture and in Terrestrial Animals, Vet. Hum. Toxicol. 40(Suppl 2), 52-55 (1998).
    • (1998) Vet. Hum. Toxicol. , vol.40 , Issue.SUPPL. 2 , pp. 52-55
    • Haley, C.J.1    Eirkson, C.2    Geil, S.3    Mahanes, B.4
  • 39
    • 0003418761 scopus 로고
    • (FDA Center for Food Safety and Applied Nutrition, Environmental Impact Section, March 1987). NTIS PB87-175345
    • U.S. FDA (U.S. Food and Drugs Administration), Environmental Assessment Technical Assistance Handbook (FDA Center for Food Safety and Applied Nutrition, Environmental Impact Section, March 1987). NTIS PB87-175345, (1987).
    • (1987) Environmental Assessment Technical Assistance Handbook
  • 41
    • 0004060307 scopus 로고    scopus 로고
    • Center for Drug Evaluation and Research & Center for Biologics Evaluation and Research, FDA, CMC 6, Revision 1 (July). 42 pp.
    • U.S. FDA (U.S. Food and Drugs Administration), Guidance for Industry - Environmental Assessment of Human Drug and Biologics Applications. Center for Drug Evaluation and Research & Center for Biologics Evaluation and Research, FDA, CMC 6, Revision 1 (July 1998). 42 pp.
    • (1998) Guidance for Industry - Environmental Assessment of Human Drug and Biologics Applications
  • 44
    • 0037923546 scopus 로고    scopus 로고
    • Development of Quantitative Structure-Activity Relationships (QSARs) and their use for priority setting in the testing strategy for endocrine disruptors
    • Tong, W., Perkins, R., Fang, H., Hong, H., Xie, Q., Branham, W., Sheehan, D.M., and Hason, J.F., Development of Quantitative Structure-Activity Relationships (QSARs) and Their Use for Priority Setting in the Testing Strategy for Endocrine Disruptors, Regulatory Res. Perspect. 1(3), 1-16 (2002).
    • (2002) Regulatory Res. Perspect. , vol.1 , Issue.3 , pp. 1-16
    • Tong, W.1    Perkins, R.2    Fang, H.3    Hong, H.4    Xie, Q.5    Branham, W.6    Sheehan, D.M.7    Hason, J.F.8
  • 45
    • 0032458218 scopus 로고    scopus 로고
    • A new highly specific method for predicting the carcinogenic potential of pharmaceuticals in rodents using enhanced MCASE QSAR-ES software
    • Matthews, E. J., Contrera, J. F., A New Highly Specific Method for Predicting the Carcinogenic Potential of Pharmaceuticals in Rodents Using Enhanced MCASE QSAR-ES software, Regul. Toxicol. Pharmacol. 28, 242-264 (1998).
    • (1998) Regul. Toxicol. Pharmacol. , vol.28 , pp. 242-264
    • Matthews, E.J.1    Contrera, J.F.2
  • 47
    • 0031458685 scopus 로고    scopus 로고
    • A computationally-based hazard identification algorithm that incorporates ligand flexibility. 1. Identification of potential androgen receptor ligands
    • Mekenyan O, Ivanov J, Karabunarliev S, Bradbury S, Ankley G, Karcher W., A Computationally-Based Hazard Identification Algorithm that Incorporates Ligand Flexibility. 1. Identification of Potential Androgen Receptor Ligands, Environ Sci Technol. 31, 3702-3711 (1997).
    • (1997) Environ. Sci. Technol. , vol.31 , pp. 3702-3711
    • Mekenyan, O.1    Ivanov, J.2    Karabunarliev, S.3    Bradbury, S.4    Ankley, G.5    Karcher, W.6
  • 49
    • 0021282856 scopus 로고
    • Quantitative structure-activity relationships and mixture toxicity studies of chloro- and alkylanilines at an acute lethal toxicity level to the Guppy (Poecilia reticulata)
    • Hermens, J. L. M., P. Leeuwangh, and A. Musch., Quantitative Structure-Activity Relationships and Mixture Toxicity Studies of Chloro- and Alkylanilines at an Acute Lethal Toxicity Level to the Guppy (Poecilia reticulata), Ecotox. Environ. Saf. 8, 388-394, (1984).
    • (1984) Ecotox. Environ. Saf. , vol.8 , pp. 388-394
    • Hermens, J.L.M.1    Leeuwangh, P.2    Musch, A.3
  • 50
    • 0020971444 scopus 로고
    • Structure-toxicity relationships for the fathead minnow, pimephales promelas: Narcotic industrial chemicals
    • Veith, G. D., D. J. Call, and L. T. Brooke., Structure-Toxicity Relationships for the Fathead Minnow, Pimephales promelas: Narcotic Industrial Chemicals, Can. J. Fish. Aquat. Sci. 40, 743-748 (1983).
    • (1983) Can. J. Fish. Aquat. Sci. , vol.40 , pp. 743-748
    • Veith, G.D.1    Call, D.J.2    Brooke, L.T.3
  • 52
    • 0029447512 scopus 로고
    • The application of Structure Activity Relationships (SARs) in the aquatic toxicity evaluation of discrete organic chemicals
    • Clements, R. G., J. V. Nabholz, M. Zeeman and C. M. Auer., The Application of Structure Activity Relationships (SARs) in the Aquatic Toxicity Evaluation of Discrete Organic Chemicals, SAR and QSAR in Environ. Res. 3, 203-215 (1995).
    • (1995) SAR and QSAR in Environ. Res. , vol.3 , pp. 203-215
    • Clements, R.G.1    Nabholz, J.V.2    Zeeman, M.3    Auer, C.M.4
  • 53
    • 0019517032 scopus 로고
    • Quantitative structure-activity relationships in fish toxicity studies. Part 1: Relationship for 50 industrial chemicals
    • Könemann, H. Quantitative Structure-Activity Relationships in Fish Toxicity Studies. Part 1: Relationship for 50 Industrial Chemicals, Toxicol. 16, 209-221 (1981).
    • (1981) Toxicol. , vol.16 , pp. 209-221
    • Könemann, H.1
  • 54
    • 0026785215 scopus 로고
    • Classifying environmental pollutants. 1: Structure-Activity relationships for prediction of aquatic toxicity
    • Veerhaar, H. J. M., C. J. van Leeuwen and J. L. M. Hermens., Classifying Environmental Pollutants. 1: Structure-Activity Relationships for Prediction of Aquatic Toxicity, Chemosphere 25, 471-491 (1992).
    • (1992) Chemosphere , vol.25 , pp. 471-491
    • Veerhaar, H.J.M.1    Van Leeuwen, C.J.2    Hermens, J.L.M.3
  • 58
    • 0036490150 scopus 로고    scopus 로고
    • Probabilistic assessment of biodegradability based on metabolic pathways: Catabol system
    • Jaworska, J., S. Dimitrov, N. Nikolova and O. Mekenyan., Probabilistic Assessment of Biodegradability Based on Metabolic Pathways: Catabol System, SAR and QSAR in Environ. Res., 13 (2), 307-323 (2002).
    • (2002) SAR and QSAR in Environ. Res. , vol.13 , Issue.2 , pp. 307-323
    • Jaworska, J.1    Dimitrov, S.2    Nikolova, N.3    Mekenyan, O.4
  • 59
    • 0026355089 scopus 로고
    • ASTER: An integration of the AQUIRE data base and the QSAR system for use in ecological risk assessments
    • Russom, C. L., Anderson, E. B., Greenwood, B. E., and Pilli, A., ASTER: An Integration of the AQUIRE Data Base and the QSAR System for Use in Ecological Risk Assessments, Sci. Total Environ. 109/110, 667-670 (1991).
    • (1991) Sci. Total Environ. , vol.109-110 , pp. 667-670
    • Russom, C.L.1    Anderson, E.B.2    Greenwood, B.E.3    Pilli, A.4
  • 60
    • 85192678347 scopus 로고    scopus 로고
    • in preparation
    • Servos, M. et al. in preparation.
    • Servos, M.1
  • 61
    • 0035449230 scopus 로고    scopus 로고
    • Sorption of veterinary medicines: A review
    • Tolls, J., Sorption of Veterinary Medicines: A Review, Environ. Sci. Technol. 35, 3397-3406 (2001).
    • (2001) Environ. Sci. Technol. , vol.35 , pp. 3397-3406
    • Tolls, J.1
  • 62
    • 0037903204 scopus 로고    scopus 로고
    • Modeling mode of action of industrial chemicals: Application using chemicals on Canada's Domestic Substances List (DSL)
    • Part of the QSAR 2002 Proceedings
    • Dimitrov, S., Koleva, Y., Lewis, M., Breton, R., Veith, G, and Mekenyan, O., Modeling Mode of Action of Industrial Chemicals: Application Using Chemicals on Canada's Domestic Substances List (DSL), QSAR and Combinatorial Science, Vol. 22(1), 5-17 (2003). [Part of the QSAR 2002 Proceedings]
    • (2003) QSAR and Combinatorial Science , vol.22 , Issue.1 , pp. 5-17
    • Dimitrov, S.1    Koleva, Y.2    Lewis, M.3    Breton, R.4    Veith, G.5    Mekenyan, O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.