Type II transmembrane serine proteases

Current Topics in Developmental Biology

Volumn 54, Issue , 2003, Pages 167-206

  Wu, Qingyu ^a  

^a BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CORIN PROTEIN, MOUSE; CRN PROTEIN, HUMAN; ENTEROPEPTIDASE; HEPSIN; MATRIPTASE; MEMBRANE PROTEIN; SERINE PROTEINASE; ST14 PROTEIN, HUMAN; TMPRSS2 PROTEIN, HUMAN; TRYPSIN;

ANIMAL; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; REVIEW;

ANIMALS; ENTEROPEPTIDASE; HUMANS; MEMBRANE PROTEINS; PROTEIN STRUCTURE, TERTIARY; SERINE ENDOPEPTIDASES; TRYPSIN;

EID: 0038463745     PISSN: 00702153     EISSN: None     Source Type: Book Series    
DOI: 10.1016/s0070-2153(03)54009-1     Document Type: Review

References (164)

1. D.E Afar I Vivanco R.S Hubert J Kuo E Chen D.C Saffran A.B Raitano A Jakobovits Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia Cancer Res. 61 2001 1686 1692
2. R.L Allgren T.C Marbury S.N Rahman L.S Weisberg A.Z Fenves R.A Lafayette R.M Sweet F.C Genter B.R Kurnik J.D Conger M.H Sayegh Anaritide in acute tubular necrosis Auriculin Anaritide Acute Renal Failure Study Group N. Engl. J. Med. 336 1997 828 834
3. L.E Anderson K.A Walsh H Neurath Bovine enterokinase Purification, specificity, and some molecular properties Biochemistry 16 1977 3354 3360
4. L.F Appel M Prout R Abu-Shumays A Hammonds J.C Garbe D Fristrom J Fristrom The Drosophila Stubble-stubbloid gene encodes an apparent transmembrane serine protease required for epithelial morphogenesis Proc. Natl. Acad. Sci. USA 90 1993 4937 4941
5. L Bartoloni M Wattenhofer J Kudoh A Berry K Shibuya K Kawasaki J Wang S Asakawa I Talior B Bonne-Tamir C Rossier J Michaud E.R McCabe S Minoshima N Shimizu H.S Scott S.E Antonarakis Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency Genomics 70 2000 190 200
6. M.P Belvin K.V Anderson A conserved signaling pathway: the Drosophila toll-dorsal pathway Annu. Rev. Cell. Dev. Biol. 12 1996 393 416
7. C Benaud R.B Dickson C.Y Lin Regulation of the activity of matriptase on epithelial cell surfaces by a blood-derived factor Eur. J. Biochem. 268 2001 1439 1447
8. C Benaud M Oberst J.P Hobson S Spiegel R.B Dickson C.Y Lin Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase J. Biol. Chem. 277 2002 10539 10546
9. T Ben-Yosef M Wattenhofer S Riazuddin Z.M Ahmed H.S Scott J Kudoh K Shibuya S.E Antonarakis B Bonne-Tamir U Radhakrishna S Naz Z Ahmed A Pandya W.E Nance E.R Wilcox T.B Friedman R.J Morell Novel mutations of TMPRSS3 in four DFNB8/B10 families segregating congenital autosomal recessive deafness J. Med. Genet. 38 2001 396 400
10. A Berry H.S Scott J Kudoh I Talior M Korostishevsky M Wattenhofer M Guipponi C Barras C Rossier K Shibuya J Wang K Kawasaki S Asakawa S Minoshima N Shimizu S Antonarakis B Bonne-Tamir Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region Genomics 68 2000 22 29
11. S Bleyl L Nelson S.J Odelberg H.D Ruttenberg B Otterud M Leppert K Ward A gene for familial total anomalous pulmonary venous return maps to chromosome 4p13-q12 Am. J. Hum. Genet. 56 1995 408 415
12. K.D Bloch J.A Scott J.B Zisfein J.T Fallon M.N Margolies C.E Seidman G.R Matsueda C.J Homcy R.M Graham J.G Seidman Biosynthesis and secretion of proatrial natriuretic factor by cultured rat cardiocytes Science 230 1985 1168 1171
13. B Bonne-Tamir A.L Destefano C.E Briggs R Adair B Franklyn S Weiss M Korostishevsky M Frydman C.T Baldwin L.A Farrer Linkage of congenital recessive deafness (gene DFNB10) to chromosome 21q22.3 Am. J. Hum. Genet. 58 1996 1254 1259
14. M.S Brown J Herz J.L Goldstein LDL-receptor structure Calcium cages, acid baths and recycling receptors Nature 388 1997 629 630 [news; comment]
15. J.C Burnett Jr. P.C Kao D.C Hu D.W Heser D Heublein J.P Granger T.J Opgenorth G.S Reeder Atrial natriuretic peptide elevation in congestive heart failure in the human Science 231 1986 1145 1147
16. K.M Cadigan R Nusse Wnt signaling: a common theme in animal development Genes Dev. 11 1997 3286 3305
17. C.F Catterall A Lyons R.B Sim A.J Day T.J Harris Characterization of primary amino acid sequence of human complement control protein factor I from an analysis of cDNA clones Biochem. J. 242 1987 849 856
18. E.G Cho M.G Kim C Kim S.R Kim I.S Seong C Chung R.H Schwartz D Park N-terminal processing is essential for release of epithin, a mouse type II membrane serine protease J. Biol. Chem. 276 2001 44581 44589
19. D Collen H.R Lijnen Basic and clinical aspects of fibrinolysis and thrombolysis Blood 78 1991 3114 3124
20. L.A Collins-Racie J.M McColgan K.L Grant E.A Diblasio-Smith J.M McCoy E.R Lavallie Production of recombinant bovine enterokinase catalytic subunit in Escherichia coli using the novel secretory fusion partner DsbA Biotechnology (NY) 13 1995 982 987
21. W.S Colucci U Elkayam D.P Horton W.T Abraham R.C Bourge A.D Johnson L.E Wagoner M.M Givertz C.S Liang M Neibaur W.H Haught T.H Lejemtel Intravenous nesiritide, a natriuretic peptide, in the treatment of decompensated congestive heart failure Nesiritide Study Group N. Engl. J. Med. 343 2000 246 253
22. L.J Dangott J.E Jordan R.A Bellet D.L Garbers Cloning of the mRNA for the protein that crosslinks to the egg peptide speract Proc. Natl. Acad. Sci. USA 86 1989 2128 2132
23. E.W Davie K Fujikawa W Kisiel The coagulation cascade: initiation, maintenance, and regulation Biochemistry 30 1991 10363 10370
24. A.J de Bold Atrial natriuretic factor: a hormone produced by the heart Science 230 1985 767 770
25. A.J de Bold H.B Borenstein A.T Veress H Sonnenberg A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats Life Sci. 28 1981 89 94
26. J.M Delabar D Theophile Z Rahmani Z Chettouh J.L Blouin M Prieur B Noel P.M Sinet Molecular mapping of twenty-four features of Down syndrome on chromosome 21 Eur. J. Hum. Genet. 1 1993 114 124
27. R Delotto P Spierer A gene required for the specification of dorsal-ventral pattern in Drosophila appears to encode a serine protease Nature 323 1986 688 692
28. J.W Dennis M Granovsky C.E Warren Glycoprotein glycosylation and cancer progression Biochim. Biophys. Acta 1473 1999 21 34
29. S.M Dhanasekaran T.R Barrette D Ghosh R Shah S Varambally K Kurachi K.J Pienta M.A Rubin A.M Chinnaiyan Delineation of prognostic biomarkers in prostate cancer Nature 412 2001 822 826
30. J.F Distefano G Beck B Lane S Zucker Role of tumor cell membrane-bound serine proteases in tumor-induced target cytolysis Cancer Res. 42 1982 207 218
31. J.F Distefano G Beck S Zucker Characterization of tumor cell membrane serine proteases by polyacrylamide gel electrophoresis J. Histochem. Cytochem. 31 1983 1233 1240
32. S.H Donaldson A Hirsh D.C Li G Holloway J Chao R.C Boucher S.E Gabriel Regulation of the epithelial sodium channel by serine proteases in human airways J. Biol. Chem. 277 2002 8338 8345
33. I.J Enyedy S.L Lee A.H Kuo R.B Dickson C.Y Lin S Wang Structure-based approach for the discovery of bis-benzamidines as novel inhibitors of matriptase J. Med. Chem. 44 2001 1349 1355
34. D Farley F Reymond H Nick Cloning and sequence analysis of rat hepsin, a cell surface serine proteinase Biochim. Biophys. Acta 1173 1993 350 352
35. R Friedrich P Fuentes-Prior E Ong G Coombs M Hunter R Oehler D Pierson R Gonzalez R Huber W Bode E.L Madison Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase J. Biol. Chem. 277 2002 2160 2168
36. B Furie B.C Furie The molecular basis of blood coagulation Cell 53 1988 505 518
37. F.K Ghishan P.C Lee E Lebenthal P Johnson C.A Bradley H.L Greene Isolated congenital enterokinase deficiency Recent findings and review of the literature Gastroenterology 85 1983 727 731
38. S.S Gottlieb M.L Kukin D Ahern M Packer Prognostic importance of atrial natriuretic peptide in patients with chronic heart failure J. Am. Coll. Cardiol. 13 1989 1534 1539
39. M Granovsky J Fata J Pawling W.J Muller R Khokha J.W Dennis Suppression of tumor growth and metastasis in Mgat5-deficient mice Nat. Med. 6 2000 306 312
40. D.A Grant A.I Magee J Hermon-Taylor Optimisation of conditions for the affinity chromatography of human enterokinase on immobilised p-aminobenzamidine Improvement of the preparative procedure by inclusion of negative affinity chromatography with glycylglycyl-aniline Eur. J. Biochem. 88 1978 183 189
41. T.M Gress C Wallrapp M Frohme F Muller-Pillasch U Lacher H Friess M Buchler G Adler J.D Hoheisel Identification of genes with specific expression in pancreatic cancer by cDNA representational difference analysis Genes Chromosomes Cancer 19 1997 97 103
42. B Hadorn J.C Haworth B Gourley A Prasad V Troesch Intestinal enterokinase deficiency Occurrence in two sibs and age dependency of clinical expression Arch. Dis. Child 50 1975 277 282
43. B Hadorn M.J Tarlow J.K Lloyd O.H Wolff Intestinal enterokinase deficiency Lancet 1 1969 812 813
44. J.H Han S.H Lee Y.Q Tan E.K Lemosy C Hashimoto Gastrulation defective is a serine protease involved in activating the receptor toll to polarize the Drosophila embryo Proc. Natl. Acad. Sci. USA 97 2000 9093 9097
45. E Hartmann T.A Rapoport H.F Lodish Predicting the orientation of eukaryotic membrane-spanning proteins Proc. Natl. Acad. Sci. USA 86 1989 5786 5790
46. J Hermon-Taylor J Perrin D.A Grant A Appleyard M Bubel A.I Magee Immunofluorescent localisation of enterokinase in human small intestine Gut 18 1977 259 265
47. A Holzinger E.M Maier C Buck P.U Mayerhofer M Kappler J.C Haworth S.P Moroz H.B Hadorn J.E Sadler A.A Roscher Mutations in the proenteropeptidase gene are the molecular cause of congenital enteropeptidase deficiency Am. J. Hum. Genet. 70 2002 20 25
48. C.C Hong C Hashimoto An unusual mosaic protein with a protease domain, encoded by the nudel gene, is involved in defining embryonic dorsoventral polarity in Drosophila Cell 82 1995 785 794
49. J.D Hooper J.A Clements J.P Quigley T.M Antalis Type II transmembrane serine proteases Insights into an emerging class of cell surface proteolytic enzymes J. Biol. Chem. 276 2001 857 860
50. J.D Hooper A.L Scarman B.E Clarke J.F Normyle T.M Antalis Localization of the mosaic transmembrane serine protease corin to heart myocytes Eur. J. Biochem. 267 2000 6931 6937
51. S Ihara E Miyoshi J.H Ko K Murata S Nakahara K Honke R.B Dickson C.Y Lin N Taniguchi Pro-metastatic effect of N-acetylglucosaminyltransferase V is due to modification and stabilization of active matriptase by adding beta 1–6 GlcNAc-branching J. Biol. Chem. 25 2002 25
52. T Imada R Takayanagi T Inagami Identification of a peptidase which processes atrial natriuretic factor precursor to its active form with 28 amino acid residues in particulate fractions of rat atrial homogenate Biochem. Biophys. Res. Commun. 143 1987 587 592
53. T Imada R Takayanagi T Inagami Atrioactivase, a specific peptidase in bovine atria for the processing of pro-atrial natriuretic factor Purification and characterization J. Biol. Chem. 263 1988 9515 9519
54. T Inagami Atrial natriuretic factor J. Biol. Chem. 264 1989 3043 3046
55. P Irving L Troxler T.S Heuer M Belvin C Kopczynski J.M Reichhart J.A Hoffmann C Hetru A genome-wide analysis of immune responses in Drosophila Proc. Natl. Acad. Sci. USA 98 2001 15119 15124
56. T Ito Y Toki N Siegel J.K Gierse P Needleman Manipulation of stretch-induced atriopeptin prohormone release and processing in the perfused rat heart Proc. Natl. Acad. Sci. USA 85 1988 8365 8369
57. E Jacquinet N.V Rao G.V Rao J.R Hoidal Cloning, genomic organization, chromosomal assignment and expression of a novel mosaic serine proteinase: epitheliasin FEBS Lett. 468 2000 93 100
58. E Jacquinet N.V Rao G.V Rao W Zhengming K.H Albertine J.R Hoidal Cloning and characterization of the cDNA and gene for human epitheliasin Eur. J. Biochem. 268 2001 2687 2699
59. Y.S Jin K.V Anderson Dominant and recessive alleles of the Drosophila easter gene are point mutations at conserved sites in the serine protease catalytic domain Cell 60 1990 873 881
60. S.W John J.H Krege P.M Oliver J.R Hagaman J.B Hodgin S.C Pang T.G Flynn O Smithies Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension Science 267 1995 679 681 [published erratum appears in Science (1995) 267, 1753]
61. S Kawamura S Kurachi Y Deyashiki K Kurachi Complete nucleotide sequence, origin of isoform and functional characterization of the mouse hepsin gene Eur. J. Biochem. 262 1999 755 764
62. Y Kazama T Hamamoto D.C Foster W Kisiel Hepsin, a putative membrane-associated serine protease, activates human factor VII and initiates a pathway of blood coagulation on the cell surface leading to thrombin formation J. Biol. Chem. 270 1995 66 72
63. D.R Kim S Sharmin M Inoue H Kido Cloning and expression of novel mosaic serine proteases with and without a transmembrane domain from human lung Biochim. Biophys. Acta 1518 2001 204 209
64. M.G Kim C Chen M.S Lyu E.G Cho D Park C Kozak R.H Schwartz Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains Immunogenetics 49 1999 420 428
65. K Kishi K Yamazaki I Yasuda N Yahagi M Ichinose Y Tsuchiya S.B Athauda H Inoue K Takahashi Characterization of a membrane-bound arginine-specific serine protease from rat intestinal mucosa J. Biochem. (Tokyo) 130 2001 425 430
66. Y Kitamoto R.A Veile H Donis-Keller J.E Sadler cDna sequence and chromosomal localization of human enterokinase, the proteolytic activator of trypsinogen Biochemistry 34 1995 4562 4568
67. Y Kitamoto X Yuan Q Wu D.W McCourt J.E Sadler Enterokinase, the initiator of intestinal digestion, is a mosaic protease composed of a distinctive assortment of domains Proc. Natl. Acad. Sci. USA 91 1994 7588 7592
68. K.J Koller D.V Goeddel Molecular biology of the natriuretic peptides and their receptors Circulation 86 1992 1081 1088
69. M.Z Kounnas D.A Chappell D.K Strickland W.S Argraves Glycoprotein 330, a member of the low density lipoprotein receptor family, binds lipoprotein lipase in vitro J. Biol. Chem. 268 1993 14176 14781
70. J Kraut Serine proteases: structure and mechanism of catalysis Annu. Rev. Biochem. 46 1977 331 358
71. M Krieger J Herz Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP) Annu. Rev. Biochem. 63 1994 601 637
72. M Kunitz Formation of trypsin from crystalline trypsinogen by means of enterokinase J. Gen. Physiol. 22 1939 429 446
73. M Kunitz Purification and concentration of enterokinase J. Gen. Physiol. 22 1939 447 450
74. K Kurachi A Torres-Rosado A Tsuji Hepsin Methods Enzymol. 244 1994 100 114
75. V.J Labombardi E Shaw J.F Distefano G Beck F Brown S Zucker Isolation and characterization of a trypsin-like serine proteinase from the membranes of Walker 256 carcino-sarcoma cells Biochem. J. 211 1983 695 700
76. R.E Lang H Tholken D Ganten F.C Luft H Ruskoaho T Unger Atrial natriuretic factor-a circulating hormone stimulated by volume loading Nature 314 1985 264 266
77. E.R Lavallie A Rehemtulla L.A Racie E.A Diblasio C Ferenz K.L Grant A Light J.M McCoy Cloning and functional expression of a cDNA encoding the catalytic subunit of bovine enterokinase J. Biol. Chem. 268 1993 23311 23317
78. S.L Lee R.B Dickson C.Y Lin Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease J. Biol. Chem. 275 2000 36720 36725
79. E.R Levin D.G Gardner W.K Samson Natriuretic peptides N. Engl. J. Med. 339 1998 321 328
80. S.P Leytus K.R Loeb F.S Hagen K Kurachi E.W Davie A novel trypsin-like serine protease (hepsin) with a putative transmembrane domain expressed by human liver and hepatoma cells Biochemistry 27 1988 1067 1074
81. J.J Liepnieks A Light The preparation and properties of bovine enterokinase J. Biol. Chem. 254 1979 1677 1683
82. A Light H Janska Enterokinase (enteropeptidase): comparative aspects Trends Biochem. Sci. 14 1989 110 112
83. A Light H Janska The amino-terminal sequence of the catalytic subunit of bovine enterokinase J. Protein Chem. 10 1991 475 480
84. B Lin C Ferguson J.T White S Wang R Vessella L.D True L Hood P.S Nelson Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2 Cancer Res. 59 1999 4180 4184
85. C.Y Lin J Anders M Johnson R.B Dickson Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk J. Biol. Chem. 274 1999 18237 18242
86. C.Y Lin J Anders M Johnson Q.A Sang R.B Dickson Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity J. Biol. Chem. 274 1999 18231 18236
87. C.Y Lin J.K Wang J Torri L Dou Q.A Sang R.B Dickson Characterization of a novel, membrane-bound, 80-kDa matrix-degrading protease from human breast cancer cells Monoclonal antibody production, isolation, and localization J. Biol. Chem. 272 1997 9147 9152
88. Z Lojda R Gossrau Histochemical demonstration of enteropeptidase activity New method with a synthetic substrate and its comparison with the trypsinogen procedure Histochemistry 78 1983 251 270
89. M.J Lopez S.K Wong I Kishimoto S Dubois V Mach J Friesen D.L Garbers A Beuve Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptide Nature 378 1995 65 68
90. D Lu J.E Sadler Handbook of Proteolytic Enzymes 1998 Academic Press Ltd London
91. D Lu K Futterer S Korolev X Zheng K Tan G Waksman J.E Sadler Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide J. Mol. Biol. 292 1999 361 373
92. D Lu X Yuan X Zheng J.E Sadler Bovine proenteropeptidase is activated by trypsin, and the specificity of enteropeptidase depends on the heavy chain J. Biol. Chem. 272 1997 31293 31300
93. J Luo D.J Duggan Y Chen J Sauvageot C.M Ewing M.L Bittner J.M Trent W.B Isaacs Human prostate cancer and benign prostatic hyperplasia: molecular dissection by gene expression profiling Cancer Res. 61 2001 4683 4688
94. J.A Magee T Araki S Patil T Ehrig L True P.A Humphrey W.J Catalona M.A Watson J Milbrandt Expression profiling reveals hepsin overexpression in prostate cancer Cancer Res. 61 2001 5692 5696
95. K.G Mann M.E Nesheim W.R Church P Haley S Krishnaswamy Surface-dependent reactions of the vitamin K-dependent enzyme complexes Blood 76 1990 1 16
96. N.S Mann S.K Mann Enterokinase Proc. Soc. Exp. Biol. Med. 206 1994 114 118
97. P.T Manning D Schwartz N.C Katsube S.W Holmberg P Needleman Vasopressin-stimulated release of atriopeptin: endocrine antagonists in fluid homeostasis Science 229 1985 395 397
98. S Maroux J Baratti P Desnuelle Purification and specificity of porcine enterokinase J. Biol. Chem. 246 1971 5031 5039
99. S Masmoudi S.E Antonarakis T Schwede A.M Ghorbel M Gratri M.P Pappasavas M Drira A Elgaied-Boulila M Wattenhofer C Rossier H.S Scott H Ayadi M Guipponi Novel missense mutations of TMPRSS3 in two consanguineous Tunisian families with non-syndromic autosomal recessive deafness Hum. Mutat. 18 2001 101 108
100. M Matsushima M Ichinose N Yahagi N Kakei S Tsukada K Miki K Kurokawa K Tashiro K Shiokawa K Shinomiya H Umeyama H Inoue T Takahashi K Takahashi Structural characterization of porcine enteropeptidase J. Biol. Chem. 269 1994 19976 19982
101. M.E McGrath W.M Hines J.A Sakanari R.J Fletterick C.S Craik The sequence and reactive site of ecotin A general inhibitor of pancreatic serine proteases from Escherichia coli J. Biol. Chem. 266 1991 6620 6625
102. P Mignatti D.B Rifkin Biology and biochemistry of proteinases in tumor invasion Physiol. Rev. 73 1993 161 195
103. K Miyazawa T Shimomura A Kitamura J Kondo Y Morimoto N Kitamura Molecular cloning and sequence analysis of the cDNA for a human serine protease reponsible for activation of hepatocyte growth factor Structural similarity of the protease precursor to blood coagulation factor XII J. Biol. Chem. 268 1993 10024 10028
104. M Molino E.S Barnathan R Numerof J Clark M Dreyer A Cumashi J.A Hoxie N Schechter M Woolkalis L.F Brass Interactions of mast cell tryptase with thrombin receptors and PAR-2 J. Biol. Chem. 272 1997 4043 4049
105. D.E Mullins S.T Rohrlich The role of proteinases in cellular invasiveness Biochim. Biophys. Acta 695 1983 177 214
106. D Naka T Ishii Y Yoshiyama K Miyazawa H Hara T Hishida N Kidamura Activation of hepatocyte growth factor by proteolytic conversion of a single chain form to a heterodimer J. Biol. Chem. 267 1992 20114 20119
107. H Neurath The versatility of proteolytic enzymes J. Cell. Biochem. 32 1986 35 49
108. M Oberst J Anders B Xie B Singh M Ossandon M Johnson R.B Dickson C.Y Lin Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo Am. J. Pathol. 158 2001 1301 1311
109. L Ossowski J.P Quigley G.M Kellerman E Reich Fibrinolysis associated with oncogenic transformation Requirement of plasminogen for correlated changes in cellular morphology, colony formation in agar, and cell migration J. Exp. Med. 138 1973 1056 1064
110. L Ossowski J.C Unkeless A Tobia J.P Quigley D.B Rifkin E Reich An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses J. Exp. Med. 137 1973 112 126
111. A Paoloni-Giacobino H Chen M.C Peitsch C Rossier S.E Antonarakis Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3 Genomics 44 1997 309 320
112. I.P Pavlov Nobel Lecture, Physiology or Medicine 1901–1921 1904 The Nobel Foundation
113. J.P Quigley L Ossowski E Reich Plasminogen, the serum proenzyme activated by factors from cells transformed by oncogenic viruses J. Biol. Chem. 249 1974 4306 4311
114. S Satomi Y Yamasaki S Tsuzuki Y Hitomi T Iwanaga T Fushiki A role for membrane-type serine protease (MT-SP1) in intestinal epithelial turnover Biochem. Biophys. Res. Commun. 287 2001 995 1002
115. C Schmidt F Bladt S Goedecke V Brinkmann W Zschiesche M Sharpe E Gherardi C Birchmeier Scatter factor/hepatocyte growth factor is essential for liver development Nature 373 1995 699 702
116. D Schwartz D.M Geller P.T Manning N.R Siegel K.F Fok C.E Smith P Needleman Ser-Leu-Arg-Arg-atriopeptin III: the major circulating form of atrial peptide Science 229 1985 397 400
117. H.S Scott J Kudoh M Wattenhofer K Shibuya A Berry R Chrast M Guipponi J Wang K Kawasaki S Asakawa S Minoshima F Younus S.Q Mehdi U Radhakrishna M.P Papasavvas C Gehrig C Rossier M Korostishevsky A Gal N Shimizu B Bonne-Tamir S.E Antonarakis Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness Nat. Genet. 27 2001 59 63
118. C.A Sei G.L Hand S.F Murray C.C Glembotski The cosecretional maturation of atrial natriuretic factor by primary atrial myocytes Mol. Endocrinol. 6 1992 309 319
119. N.G Seidah J.A Cromlish J Hamelin G Thibault M Chretien Homologous IRCM-serine protease 1 from pituitary, heart atrium and ventricle: a common pro-hormone maturation enzyme Biosci. Rep. 6 1986 835 844
120. Y.E Shi J Torri L Yieh A Wellstein M.E Lippman R.B Dickson Identification and characterization of a novel matrix-degrading protease from hormone-dependent human breast cancer cells Cancer Res. 53 1993 1409 1415
121. P.P Shields C.C Glembotski The post-translational processing of rat pro-atrial natriuretic factor by primary atrial myocyte cultures J. Biol. Chem. 263 1988 8091 8098
122. T Shimomura K Denda A Kitamura T Kawaguchi M Kito J Kondo S Kagaya L Qin H Takata K Miyazawa N Kitamura Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitor J. Biol. Chem. 272 1997 6370 6376
123. J.M Shulman N Perrimon J.D Axelrod Frizzled signaling and the developmental control of cell polarity Trends Genet. 14 1998 452 458
124. T.A Stamey J.E McNeal C.M Yemoto B.M Sigal I.M Johnstone Biological determinants of cancer progression in men with prostate cancer J. Am. Med. Assoc. 281 1999 1395 1400
125. T.A Stamey J.A Warrington M.C Caldwell Z Chen Z Fan M Mahadevappa J.E McNeal R Nolley Z Zhang Molecular genetic profiling of Gleason grade 4/5 prostate cancers compared to benign prostatic hyperplasia J. Urol. 166 2001 2171 2177
126. F Stewart Roles of mesenchymal-epithelial interactions and hepatocyte growth factor-scatter factor (HGF-SF) in placental development Rev. Reprod. 1 1996 144 148
127. M Stoker E Gherardi M Perryman J Gray Scatter factor is a fibroblast-derived modulator of epithelial cell mobility Nature 327 1987 239 242
128. R.M Stroud A family of protein-cutting proteins Sci. Am. 231 1974 74 88
129. T Takeuchi J.L Harris W Huang K.W Yan S.R Coughlin C.S Craik Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates J. Biol. Chem. 275 2000 26333 26342
130. T Takeuchi M.A Shuman C.S Craik Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue Proc. Natl. Acad. Sci. USA 96 1999 11054 11061
131. H Tanimoto Y Yan J Clarke S Korourian K Shigemasa T.H Parmley G.P Parham O.B TJ Hepsin, a cell surface serine protease identified in hepatoma cells, is overexpressed in ovarian cancer Cancer Res. 57 1997 2884 2887
132. D.S Thorpe D.L Garbers The membrane form of guanylate cyclase Homology with a subunit of the cytoplasmic form of the enzyme J. Biol. Chem. 264 1989 6545 6549
133. Y Tomita D.H Kim K Magoori T Fujino T.T Yamamoto A novel low-density lipoprotein receptor-related protein with type II membrane protein-like structure is abundant in heart J. Biochem. (Tokyo) 124 1998 784 789
134. A Torres-Rosado O.S KS A Tsuji S.H Chou K Kurachi Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth Proc. Natl. Acad. Sci. USA 90 1993 7181 7185
135. A Tsuji A Torres-Rosado T Arai M.M Le Beau R.S Lemons S.H Chou K Kurachi Hepsin, a cell membrane-associated protease Characterization, tissue distribution, and gene localization J. Biol. Chem. 266 1991 16948 16953
136. Y Uehara O Minowa C Mori K Shiota J Kuno T Noda N Kitamura Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor Nature 373 1995 702 705
137. L.J Underwood K Shigemasa H Tanimoto J.B Beard E.N Schneider Y Wang T.H Parmley T.J O'Brien Ovarian tumor cells express a novel multi-domain cell surface serine protease Biochim. Biophys. Acta 1502 2000 337 350
138. J Unkeless K Dano G.M Kellerman E Reich Fibrinolysis associated with oncogenic transformation Partial purification and characterization of the cell factor, a plasminogen activator J. Biol. Chem. 249 1974 4295 4305
139. J.C Unkeless A Tobia L Ossowski J.P Quigley D.B Rifkin E Reich An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses J. Exp. Med. 137 1973 85 111
140. A Veske R Oehlmann F Younus A Mohyuddin B Muller-Myhsok S.Q Mehdi A Gal Autosomal recessive non-syndromic deafness locus (DFNB8) maps on chromosome 21q22 in a large consanguineous kindred from Pakistan Hum. Mol. Genet. 5 1996 165 168
141. T.K.H Vu R.W Liu C.J Haaksma J.J Tomasek E.W Howard Identification and cloning of the membrane-associated serine protease, hepsin, from mouse preimplantation embryos J. Biol. Chem. 272 1997 31315 31320
142. C Wallrapp S Hahnel F Muller-Pillasch B Burghardt T Iwamura M Ruthenburger M.M Lerch G Adler T.M Gress A novel transmembrane serine protease (TMPRSS3) overexpressed in pancreatic cancer Cancer Res. 60 2000 2602 2606
143. M Wattenhofer K Shibuya J Kudoh R Lyle J Michaud C Rossier K Kawasaki S Asakawa S Minoshima A Berry B Bonne-Tamir N Shimizu S.E Antonarakis H.S Scott Isolation and characterization of the UBASH3A gene on 21q22.3 encoding a potential nuclear protein with a novel combination of domains Hum. Genet. 108 2001 140 147
144. J.B Welsh L.M Sapinoso A.I Su S.G Kern J Wang-Rodriguez C.A Moskaluk H.F Frierson G.M Hampton Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer Cancer Res. 61 2001 5974 5978
145. M.R Wilkins J Redondo L.A Brown The natriuretic-peptide family Lancet 349 1997 1307 1310
146. F Wu W Yan J Pan J Morser Q Wu Processing of pro-atrial natriuretic peptide by corin in cardiac myocytes J. Biol. Chem. 277 2002 16900 16905
147. Q Wu Gene targeting in hemostasis Hepsin. Front. Biosci. 6 2001 D192 D200
148. Q Wu D Yu J Post M Halks-Miller J.E Sadler J Morser Generation and characterization of mice deficient in hepsin, a hepatic transmembrane serine protease J. Clin. Invest. 101 1998 321 326
149. N Yahagi M Ichinose M Matsushima Y Matsubara K Miki K Kurokawa H Fukamachi K Tashiro K Shiokawa T Kageyama T Takahashi H Inoue K Takahashi Complementary DNA cloning and sequencing of rat enteropeptidase and tissue distribution of its mRNA Biochem. Biophys. Res. Commun. 219 1996 806 812
150. N Yamaguchi A Okui T Yamada H Nakazato S Mitsui Spinesin/TMPRSS5, a novel transmembrane serine protease, cloned from human spinal cord J. Biol. Chem. 277 2002 6806 6812
151. K Yamaoka K Masuda H Ogawa K Takagi N Umemoto S Yasuoka Cloning and characterization of the cDNA for human airway trypsin-like protease J. Biol. Chem. 273 1998 11895 11901
152. W Yan N Sheng M Seto J Morser Q Wu Corin, a mosaic transmembrane serine protease encoded by a novel cDNA from human heart J. Biol. Chem. 274 1999 14926 14935
153. W Yan F Wu J Morser Q Wu Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme Proc. Natl. Acad. Sci. USA 97 2000 8525 8529
154. S Yasuoka T Ohnishi S Kawano S Tsuchihashi M Ogawara K Masuda K Yamaoka M Takahashi T Sano Purification, characterization, and localization of a novel trypsin-like protease found in the human airway Am. J. Respir. Cell. Mol. Biol. 16 1997 300 308
155. I.S Yu H.J Chen Y.S Lee P.H Huang S.R Lin T.W Tsai S.W Lin Mice deficient in hepsin, a serine protease, exhibit normal embryogenesis and unchanged hepatocyte regeneration Thromb. Haemost. 84 2000 865 870
156. X Yuan X Zheng D Lu D.C Rubin C.Y Pung J.E Sadler Structure of murine enterokinase (enteropeptidase) and expression in small intestine during development Am. J. Physiol. 274 1998 G342 G349
157. L.R Zacharski D.L Ornstein V.A Memoli S.M Rousseau W Kisiel Expression of the factor VII activating protease, hepsin, in situ in renal cell carcinoma [letter] Process Citation Thromb. Haemost. 79 1998 876 877
158. T.S Zamolodchikova E.A Sokolova S.L Alexandrov II Mikhaleva I.A Prudchenko I.A Morozov N.V Kononenko O.A Mirgorodskaya U Da N.I Larionova V.F Pozdnev D Ghosh W.L Duax T.I Vorotyntseva Subcellular localization, substrate specificity and crystallization of duodenase, a potential activator of enteropeptidase Eur. J. Biochem. 249 1997 612 621
159. T.S Zamolodchikova E.A Sokolova D Lu J.E Sadler Activation of recombinant proenteropeptidase by duodenase FEBS Lett. 466 2000 295 299
160. T.S Zamolodchikova T.I Vorotyntseva V.K Antonov Duodenase, a new serine protease of unusual specificity from bovine duodenal mucosa Purification and properties Eur. J. Biochem. 227 1995 866 872
161. T.S Zamolodchikova T.I Vorotyntseva I.V Nazimov G.A Grishina Duodenase, a new serine protease of unusual specificity from bovine duodenal mucosa Primary structure of the enzyme Eur. J. Biochem. 227 1995 873 879
162. X Zheng D Lu J.E Sadler Apical sorting of bovine enteropeptidase does not involve detergent-resistant association with sphingolipid-cholesterol rafts J. Biol. Chem. 274 1999 1596 1605
163. X Zheng J.E Sadler Mucin-like domain of enteropeptidase directs apical targeting in Madin-Darby canine kidney cells J. Biol. Chem. 277 2002 6858 6863
164. A Zhukov U Hellman M Ingelman-Sundberg Purification and characterization of hepsin from rat liver microsomes Biochim. Biophys. Acta 1337 1997 85 95