Prolactin suppresses glucocorticoid-induced thymocyte apoptosis in vivo

Endocrinology

Volumn 144, Issue 5, 2003, Pages 2102-2110

  Krishnan, Nithya ^a   Thellin, Olivier ^c   Buckley, Donna J ^a   Horseman, Nelson D ^a,c   Buckley, Arthur R ^a,b  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c 4260 Medical Sciences Building ^*

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; GLUCOCORTICOID; PROLACTIN; CORTICOSTERONE; DEXAMETHASONE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CELLULAR IMMUNITY; ENZYME ACTIVATION; EVOKED RESPONSE; IMMUNE SYSTEM; LYMPHOID CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; THYMOCYTE; ANIMAL; BLOOD; C57BL MOUSE; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION; GENETICS; MOUSE MUTANT; PHYSIOLOGY; SPLEEN; THYMUS;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CORTICOSTERONE; DEXAMETHASONE; GENE EXPRESSION; GLUCOCORTICOIDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROLACTIN; SPLEEN; THYMUS GLAND;

EID: 0038408966     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0053     Document Type: Article

References (71)

1. Selye H 1978 The stress of life. New York: McGraw-Hill Book Co.
2. Breslau N, Davis GC 1986 Chronic stress and major depression. Arch Gen Psychiatry 43:309-314
3. Galosy RA, Clark LK, Vasko MR, Crawford IL 1981 Neurophysiology and neuropharmacology of cardiovascular regulation and stress. Neursosci Biobehav Rev 5:137-175
4. Tapp WN, Natelson BH 1988 Consequences of stress: a multiplicative function of health status. FASEB J 2:2268-2271
5. Millan S, Gonzalez-Quijano MI, Giordano M, Soto L, Martin AI, Lopez-Calderon A 1996 Short and long restraint differentially affect humoral and cellular immune functions. Life Sci 59:1431-1442
6. Fujiwara R, Shibata H, Komori T, Yokoyama MM, Okazaki Y, Ohmori M 1999 The mechanisms of immune suppression by high pressure stress in mice. J Pharm Pharmacol 51:1397-1404
7. Shimizu T, Kawamura T, Miyaji C, Oya H, Bannai M, Yamamoto S, Weerasinghe A, Halder RC, Watanabe H, Hatakeyama K, Abo T 2000 Resistance of extrathymic T cells to stress and the role of endogenous glucocorticoids in stress associated immunosuppression. Scand J Immunol 51:285-292
8. Tarcic N, Ovadia H, Weiss DW, Weidenfeld J 1998 Restraint stress-induced thymic involution and cell apoptosis are dependent on endogenous glucocorticoids. J Neuroimmunol 82:40-46
9. Ayala A, Herdon CD, Lehman DL, DeMaso CM, Ayala CA, Chaudry IH 1995 The induction of accelerated thymic programmed cell death during polymicrobial sepsis: control by corticosteroids but not tumor necrosis factor. Shock 3:259-267
10. Compton MM, Cidlowski JA 1986 Rapid in viva effects of glucocorticoids on the integrity of rat lymphocyte genomic deoxyribonucleic acid. Endocrinology 118:38-45
11. Wyllie AH 1980 Glucocorticoid-induced thymocytes apoptosis is associated with endogenous endonuclease activation. Nature 284:555-556
12. Ashwell JD, Lu FW, Vacchio MS 2000 Glucocorticoids in T cell development and function. Annu Rev Imunol 18:309-345
13. Kelley KW, Dantzer R 1991 Growth hormone and prolactin as natural antagonists of glucocorticoids in immunoregulation. In: Plotnikoff N, Murgo A, Faith R, Wybran J, eds. Stress and immunity. Boca Raton, FL: CRC Press; 433-452
14. Snell GD 1929 Dwarf: a new Mendelian recessive character of the house mouse. Proc Natl Acad Sci USA 15:733-734
15. Li S, Creshaw EB, Rawson EJ, Simmons DM, Swanson LW, Rosenfeld MG 1990 Dwarf Locus mutants lacking three pituitary cell types result from mutations in the pou-domain gene pit-1. Nature 347:528-533
16. Baroni C 1968 Mouse thymus in hereditary pituitary dwarfism. Acta Anat 68:361-373
17. Pierpaoli W, Baroni C, Fabris N, Sorkin E 1969 Hormones and the immunological capacity II. Reconstitution of antibody production in hormonally deficient mice by somatotropic hormone, thyrotropic hormone and thyroxin. Immunology 16:217-230
18. Baroni CD, Fabris N, Bertoli G 1969 Effects of hormones on development and function of lymphoid tissues. Synergistic action of thyroxin and somatropic hormone in pituitary dwarf mice Immunology 17:303-314
19. Murphy WJ, Durum SK, Longo DL 1992 Role of neuroendocrine hormones in murine T cell development. Growth hormone exerts thymopoietic effects in vivo J Immunol 149:3851-3857
20. Dumont F, Robert F, Bischoff P 1979 T and B lymphocytes in pituitary dwarf snell-bagg mice. Immunology 38:23-31
21. Fabris N, Pierpaoli W, Sorkin E 1971 Hormones and the immunological capacity III. The immunodeficiency disease of the hypopituitary snell-bagg dwarf mouse. Clin Exp Immunol 9:209-225
22. Duquesnoy JR 1972 Immunodeficiency of the thymus-dependent system of the ames dwarf mouse. J Immunol 108:1578-1590
23. Horseman ND, Zhao W, Montecino-Rodriguez E, Tanaka M, Nakashima K, Engle SJ, Smith F, Markoff E, Dorshkind K 1997 Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene. EMBO J 16:6929-6935
24. Foster MP, Jensen ER, Montecino-Rodriguez E, Leathers H, Horseman ND, Dorshkind K 2000 Humoral and cell-mediated immunity in mice with genetic deficiencies of prolactin, growth hormone, insulin-like growth factor-1, and thyroid hormone. Clin Immunol 96:140-149
25. Bouchard B, Ormandy CJ, Di Santo JP, Kelly PA 1999 Immune system development and function in prolactin receptor-deficient mice. J Immunol 163:576-582
26. Fletcher-Chiappini SE, Compton MM, La Voie HA, Day EB, Witorsch RJ 1993 Glucocorticoid-prolactin interactions in Nb2 lymphoma cells: antiproliferative versus anticytolytic effects. Proc Soc Exp Biol Med 202:345-352
27. Witorsch RJ, Day EB, LaVoie HA, Hashemi N, Taylor JK 1993 Comparison of glucocorticoid-induced effects in prolactin-dependent and autonomous rat Nb2 lymphoma cells Proc Soc Exp Biol Med 203:454-446
28. LaVoie HA, Witorsch RJ 1995 Investigation of intracellular signals mediating the anti-apoptotic action of prolactin in Nb2 lymphoma cells. Proc Soc Exp Biol Med 209:257-269
29. Leff MA, Buckley DJ, Krumenacker JS, Reed JC, Miyashita T, Buckley AR 1996 Rapid modulation of the apoptosis regulatory genes, bcl-2 and bax by prolactin in rat Nb2 lymphoma cells. Endocrinology 137:5456-5462
30. Deleted in proof
31. Buckley AR, Buckley DJ, Leff MA, Magnuson NS 1995 Rapid induction of pim-1 expression by prolactin and IL-2 in rat Nb2 lymphoma cells. Endocrinology 136:5252-5259
32. Krishnan N, Buckley DJ, Zhang M, Reed JC, Buckley AR 2001 Prolactin-induced X-linked inhibitor of apoptosis protein expression during S phase cell cycle progression in rat Nb2 lymphoma cells. Endocrine 15:177-186
33. Khurana S, Liby K, Buckley AR, Ben-Jonathan N 1999 Proteolysis of human prolactin: resistance to cathepsin D and formation of a nonangiostatic, C-terminal 16K fragment by thrombin. Endocrinology 140:4127-4132
34. Tanaka T, Shiu RP, Gout PW, Beer CT, Noble RL, Friesen H 1980 A new sensitive and specific bioassay for lactogenic hormones: measurement of prolactin and growth hormone in human serum. J Clin Endocrinol Metab 51:1058-1063
35. Krumenacker JS, Buckley DJ, Leff MA, McCormack JT, Dejong G, Gout PW, Reed JC, Miyashita T, Magnuson NS, Buckley AR 1998 Prolactin-regulated apoptosis of Nb2 lymphoma cells: pim-1, bcl-2, and bax expression. Endocrine 9:163-170
36. Mann CL, Hughes Jr FM, Cidlowski JA 2000 Delineation of signalling pathways involved in glucocorticoid-induced and spontaneous apoptosis of rat thymocytes. Endocrinology 141:528-538
37. Holcik M, Korneluk RG 2001 XIAP: a guardian angel. Nat Rev Mol Cell Biol 2:550-556
38. LaCasse EC, Baird S, Korneluk RG, MacKenzie AE 1998 The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 17:3247-3259
39. Buckley AR 2001 Prolactin, a lymphocyte growth and survival factor. Lupus 10:684-690
40. Ahmed SA, Sriranganathan N 1994 Differential effects of dexamethasone on thymus and spleen: alterations in programmed cell death, lymphocyte subsets, and activation of T cells. Immunopharmacology 28:55-56
41. Richards RC, Beardmore JM 1984 Prolactin concentrations in mouse milk during lactation. Experientia 40:757-758
42. Meerlo P, Easton A, Bergmann BM, Turek FW 2001 Restraint increases prolactin and REM sleep in C57BL/6J mice but not BALB/cJ mice. Am. J Physiol Regul Integr Comp Physiol 281:R846-R854
43. Matera L, Casano A, Bellone G, Oberholtzer E 1992 Modulatory effect of prolactin on the resting and mitogen-induced activity of T, B, and NK lymphocytes. Brain Behav Immun 6:409-417
44. Athreya BH, Pletcher J, Zulian F, Weiner DB, Williams WV 1993 Subsetspecific effects of sex hormones and pituitary gonadotropins on human lymphocyte proliferation in vitro. Clin Immunol Immunopathol 66:201-211
45. Dogusam Z, Book ML, Verdood P, Yu-Lee LY, Hooghe-Peters EL 2000 Prolactin activates interferon regulatory-1 expression in normal lympho-hemopoietic cells. Eur Cytokine Netw 11:435-442
46. Yu-Lee L-Y, Hrachovy JA, Stevens AM, Schwarz LA 1990 Interferon-regulatory factor 1 is an immediate-early gene under transcriptional regulation by prolactin in Nb2 T cells. Mol Cell Biol 10:3087-3084
47. Clevenger CV, Russell DH, Appasamy PM, Prystowsky MB 1990 Regulation of IL2-d riven T-lymphocyte proliferation by prolactin. Proc Natl Acad Sci USA 87:6460-6464
48. Hartmann DP, Holoday JW, Bernton EW 1989 Inhibition of lymphocyte proliferation by antibodies to prolactin. FASEB J 3:2194-2202
49. Berczi I, Nagy E, Kovacs K, Horvath E 1981 Regulation of humoral immunity in rats by pituitary hormones. Acta Endocrinol 98:506-513
50. Nagy E, Berczi I 1981 Prolactin and contact sensitivity. Allergy 36:429-432
51. Berczi I, Nagy E, Asa SL, Kovacs K 1984 The influence of pituitary hormones on adjuvant arthritis. Rheumatology 27:682-688
52. Morris RG, Hargreaves AD, Duvall E, Wyllie AH 1984 Hormone-induced cell death. 2. Surface changes in thymocytes undergoing apoptosis. Am J Pathol 115:426-436
53. Fadock VA, Voelker DR, Campbell PA, Cohen JJ, Bratton DL, Henson PM 1992 Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 148:2207-2216
54. Liu X, Zou H, Slaughter C, Wang X 1997 DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89:175-184
55. Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M, Lazebnik YA, Munday NA, Raju SM, Smulson ME, Yamin TT, Yu VL, Miller DK 1995 Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376:37-43
56. Deveraux QL, Takahashi R, Salvesen GS, Reed JC 1997 X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388:300-304
57. Johnson DE, Gastman BR, Wieckowski E, Wang GQ, Amoscato A, Delach SM, Rabinowich H 2000 Inhibitor of apoptosis hILP undergoes caspase-mediated cleavage during T lymphocyte apoptosis. Cancer Res 60:1818-1823
58. Conte D, Wong JW, Wright KE, Korneluk RG 2001 Thymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturation. Proc Natl Acad Sci USA 98:5049-5054
59. Krishnan N, Buckley, DJ, Buckley AR, Prolactin inhibits glucocorticoid-induced ubiquitination and proteasomal degradation of XIAP in Nb2 lymphoma cells. Program of the 84th Annual Meeting of The Endocrine Society, San Francisco, CA, 2002, p 588 (Abstract P3-288)
60. Holcik M, Lefebvre CA, Yeh C, Chow T, Kornleuk RG 1999 A new internalribosome-entry-site motif potentiates XIAP-mediated cytoprotection. Nature Cell Biol 1:90-192
61. Holcik, Yeh C, Korneluk RG, Chow T 2000 Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death. Oncogene 19:4174-4177
62. Edery M, Binart N, Bouchard B, Goffin V, Kelly PA 2001 Prolactin receptors. In: Horseman ND, ed Prolactin. Boston: Kluwer Academic Publishers; 355-380
63. Horseman ND 2002 Prolactin receptor diversity in humans: novel isoforms suggest general principles Trends Endocrinol Metab 13:47-48
64. Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA 1998 Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev 19:225-268
65. Chang W-P, Clevenger CV 1996 Modulation of growth factor receptor function by isoform heterodimerization. Proc Natl Acad Sci USA 93:5947-5952
66. Dugan AL, Thellin O, Buckley DJ, Buckley AR, Ogle AK, Horseman ND 2002 Effects of prolactin deficiency on myelopoiesis and splenic T lymphocyte proliferation in thermally injured mice. Endocrinology 143:4147-4151
67. Chen CL, Amenomori V, Lu KH, Meites J 1970 Serum prolactin levels in rats with pituitary transplants or hypothalamic lesions. Neuroendocrinology 6:220-227
68. Aguadn LI, Gimenez AR, Rodriguez EM 1977 Plasma PRL levels in female rats bearing pars distalis or total pituitary gland grafts under the kidney capsule J Endocrinol 72:399-400
69. Chodoroff B, Chodoroff G, Gala RR 1977 Influence of dopamine infusion on plasma prolactin released by kidney capsule transplanted anterior pituitaries. Experientia 33:733-734
70. Welsch CW, Negro Vilar A, Meites J 1968 Effect of piuitary homografts on host pituitary PRL and hypothalamic PIF levels Neuroendocrinology 3:238-245
71. Lilly AA, Mehlman PT, Higley JD 1999 Trait-like immunological and hematological measures in female rhesus across varied environmental conditions. Am J Primatol 48:197-223