Rapid modulation of the apoptosis regulatory genes, bcl-2 and bax by prolactin in rat Nb2 lymphoma cells

Endocrinology

Volumn 137, Issue 12, 1996, Pages 5456-5462

  Leff, Matthew A ^a   Buckley, Donna J ^a   Krumenacker, Joshua S ^a   Reed, John C ^b   Miyashita, Toshiyuki ^b   Buckley, Arthur R ^a  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; MESSENGER RNA; PROLACTIN; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; IMMEDIATE EARLY GENE; LYMPHOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROLACTIN RELEASE; PROTO ONCOGENE; RAT;

EID: 0030457869     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.12.8940371     Document Type: Article

References (48)

1. Rui H, Kirken RA, Farrar WL 1994 Activation of receptor-associated tyrosine kinase JAK 2 by prolactin. J Biol Chem 269:5364-5368
2. Clevenger CV, Toriqoe T, and Reed JC 1994 Prolactin induces rapid phosphorylation and activation of prolactin receptor associated Raf-1 kinase in a T-cell line. J Biol Chem 269:5559-5565
3. Buckley AR, Rao Y-P, Buckley DJ, Gout PW 1994 Prolactin-induced phosphorylation and nuclear translocation of MAP kinase in Nb2 lymphoma cells. Biochem Biophys Res Commun 204:1158-1164
4. Buckley AR, Buckley DJ, Leff MA, Hoover DS, Magnuson NS 1995 Rapid induction ot pim-1 expression by prolactin and interleukin-2 in rat Nb2 lymphoma cells. Endocrinology 136:5252-5259
5. Fletcher-Chiappini SE, Comptom MM, LaVoie HA, Day EB, Witorsch RJ 1993 Glucocorticoid-prolactin interactions in Nb2 lymphoma cells: antiproliferative vs. anticytolytic effects. Proc Soc Exp Biol Med 202:345-352
6. Richards JF, Beer CT, Bourgeault C, Chen K, Gout PW 1982 Biochemical response of lymphoma cells to mitogenic stimulation by prolactin. Mol Cell Endocrinol 26:41-49
7. Yu-Lee L-Y, Hrachovy JA, Stevens AM, Schwarz LA 1990 Interferon-regulatory factor 1 is an immediate-early gene under transcriptional regulation by prolactin in Nb2 cells. Mol Cell Biol 10:3084-3087
8. Murphy PR, DiMattia GE, Friesen HG 1988 Role of calcium in prolactin-stimulated c-myc gene expression and mitogenesis in Nb2 lymphoma cells. Endocrinology 122:2476-2485
9. Buckley AR, Buckley DJ, Gout PW, Liang H, Rao YP, Blake MJ 1993 Inhibition by genistein of prolactin-induced Nb2 lymphoma cell mitogenesis. Mol Cell Endocrinol 98:17-25
10. Gout PW 1987 Transient requirement for prolactin as a growth initiator following treatment of autonomous Nb2 node rat lymphoma cell cultures with butyrate. Cancer Res 47:1751-1755
11. Horsman DE, Masui S, Gout PW 1991 Karyotypic changes associated with loss of prolactin dependency of rat Nb2 node lymphoma cell cultures. Cancer Res 51:282-287
12. Witorsch RJ, Day EB, LaVoie HA, Hashemi N, Taylor JK 1993 Comparison of glucocorticoid-induced effects in prolactin-dependent and autonomous rat Nb2 lymphoma cells. Proc Soc Exp Biol Med 203:454-460
13. 11 on chromosome 14 and near a transcriptional unit on 18. Cell 41:889-901
14. Cleary ML, Sklar J 1985 Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint cluster region near a transcriptionally active locus on chromosome 18. Proc Natl Acad Sci USA 82:7439-7443
15. Tsujimoto Y, Gorham J, Cossman J Jaffe E, Croce CM 1985 The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science 229:1390-1393
16. Oltvai ZN, Milliman CL, Korsmeyer SJ 1993 Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619
17. Ohta K, Iwai K, Kasahara Y, Taniguchi N, Krajewski S, Reed JC, Miyawaki T 1995 Immunoblot analysis of cellular expression of Bcl-2 family proteins, Bcl-2, Bax, Bcl-x and Mcl-1, in peripheral blood and lymphoid tissues. Internat Immunol 7:1817-1825
18. Tsujimoto Y, Crose CM 1986 Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc Natl Acad Sci 83:5214-5218
19. McDonnell TJ, Deane N, Platt FM, Nunez G, Jaeger U, McKearn JP, Korsmeyer SJ 1989 bcl-2-immunoglobin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell 57:79-88
20. McDonnell TJ, Nunez G, Platt FM, Hockenbery D, London L, McKearn JP, Korsmeyer SJ 1990 Deregulated bcl-2-immunoglobin transgene expands a resting but responsive immunoglobulin M and D-expressing B cell population. Mol Cell Biol 10:1901-1907
21. McDonnell TJ, Korsmeyer SJ 1991 Progression from lymphoid hyperplasia to high grade malignant lymphoma in mice transgenic for the t(14;18). Nature 349:254-256
22. Acton D, Domen J, Jacobs H, Vlaar M, Korsmeyer S, Berns A 1992 Collaboration of Pim-1 and Bcl-2 in lymphomagenesis. Curr Top Microbiol Immunol 182:293-298
23. Reed JC, Cuddy M, Haldar S, Croce C, Nowell P, Makover D, Bradley K 1990 BCL-2- mediated tumorigenicity of a human T-lymphoid cell line: Synergy with MYC and inhibition by BCL-2 antisense. Proc Natl Acad Sci USA 87:3660-3664
24. Moroy T, Grzeschiczek A, Petzold S, Hartmann K-U 1993 Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in 1pr/1pr mice. Proc Natl Acad Sci USA 90:10734-10738
25. Wagner AJ, Small MB, Hay N 1993 Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2. Mol Cell Biol 13:2432-2440
26. Yin X-M, Oltvai ZN, Korsmeyer SJ 1994 BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 369:321-323
27. Zha H, Aime-Sempe C, Sato T, Reed JC 1996 Proapoptotic protein Bax heterodimerizes with Bcl-2 and Homodimerizes with Bax via a novel domain (BH 3) distinct from BH 1 and BH 2. J Biol Chem 271:7440-7444
28. Oltvai ZN, Korsmeyer SJ 1994 Checkpoints of dueling dimers foil death wishes. Cell 79:189-192
29. Krajewski S, Krajewska M, Shabaik A, Miyashita T, Wang HG, Reed JC 1994 Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2. Am J Pathol 145:1323
30. Gout PW, Beer CT, Noble RL 1980 Prolactin-stimulated growth of cell cultures established from malignant Nb rat lymphomas. Cancer Res 40:2433-2436
31. Feinberg AP, Vogelstein B 1983 A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132:6-13
32. Church GM, Gilbert W 1984 Genomic sequencing. Proc Natl Acad Sci USA 81:1991-1995
33. Blake MJ, Buckley AR, Zhang M, Buckley DJ, Lavoi KP 1995 A novel heat shock response in prolactin-dependent Nb2 node lymphoma cells. J Biol Chem 270:29614-29620
34. Reed JC, Tsujimoto Y, Epstein SF, Cuddy M, Slabiak T, Nowell PC, Croce CM 1989 Regulation of bcl-2 gene expression in lymphoid cell lines containing normal 18 or t(14;18) chromosomes. Oncogene Res 4:271-282
35. Seto M, Jaeger U, Hockett RD, Graninger W, Bennett S, Goldman P, Korsmeyer SJ 1988 Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2 fusion gene in lymphoma. EMBO J 7:123-131
36. Reed JC, Tsujimoto Y, Alpers JD, Croce CM, Nowell PC 1987 Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation. Science 236:1295-1299
37. Horseman ND, Yu-Lee L-Y 1994 Transcriptional regulation by the helix bundle pepticle hormones: growth hormone, prolactin, and hematopoietic cytokines Endocr Rev 15:627-649
38. Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ 1990 Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336
39. Oltvai Z, Milliman C, Korsmeyer SJ 1993 Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619
40. Reed JC 1994 Bcl-2 and the regulation of programmed cell death. J Cell Biol 124:1-6
41. Broome HE, Dargan CM, Krajewski S, Reed JC 1995 Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawl. J Immunol 155:2311-2317
42. Broome HE, Dargon CM, Bessent EF, Krajewski S, Reed JC 1995 Apoptosis and Bcl-2 expression in cultured murine splenic T cells. Immunology 84:375-382
43. Keith FJ, Bradbury DA, Zhu Y-M, Russell NH 1995 Inhibition of bcl-2 with antisense oligonucleotides induces apoptosis and increases the sensitivity of AML to Ara-C. Leukemia 9:131-138
44. Kitada S, Takayama S, De-Reil K, Tanaka S, Reed JC 1994 Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression. Antisense Res Dev 4:71-79
45. Strasser A, Harris AW, Cory 1991 bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 67:889-899
46. Sentman CL, Shutter JR, Hockenbery D, Kanagawa O, Korsmeyer SJ 1991 bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67:879-888
47. Miyashita T, Reed JC 1992 bcl-2 gene transfer increases relative resistance of s49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res 52:5407-5411
48. Xu C, Meikrantz W, Schlegel R, Sager R 1995 The human papilloma virus 16E6 gene sensitizes human mammary epithelial cells to apoptosis induced by DNA damage. Proc Natl Acad Sci USA 92:7829-7833