Restraint stress-induced thymic involution and cell apoptosis are dependent on endogenous glucocorticoids

Journal of Neuroimmunology

Volumn 82, Issue 1, 1998, Pages 40-46

  Tarcic, Nora ^b   Ovadia, Haim ^a   Weiss, David W ^b   Weidenfeld, Joseph ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY   (Israel)

Author keywords

Apoptosis; Corticosterone; Neuroimmunomodulation; Restraint stress; Thymus

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; RU 28486; UNCLASSIFIED DRUG;

ADRENALECTOMY; ANIMAL CELL; APOPTOSIS; ARTICLE; DRUG RECEPTOR BINDING; HORMONAL REGULATION; IMMUNOREGULATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STRESS; THYMUS FUNCTION;

ADRENALECTOMY; ADRENOCORTICOTROPIC HORMONE; ANIMALS; APOPTOSIS; CD4-CD8 RATIO; CELL COUNT; CORTICOSTERONE; DNA FRAGMENTATION; HORMONE ANTAGONISTS; IMMUNOPHENOTYPING; MALE; METYRAPONE; MICE; MICE, INBRED BALB C; MIFEPRISTONE; NEUROIMMUNOMODULATION; ORGAN SIZE; RESTRAINT, PHYSICAL; STRESS; THYMUS GLAND;

EID: 0032006752     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(97)00186-0     Document Type: Article

References (53)

1. Ader R., Felten D., Cohen N. Interaction between the brain and the immune system. Ann. Rev. Pharmacol. Toxicol. 30:1990;561-602.
2. Besedovsky H.O., del Rey A. Immune-neuro-endocrine interactions: Facts and hypotheses. Endocr. Rev. 17:1996;64-102.
3. Blalock J.E. A molecular basis for bidirectional communication between the immune and neuroendocrine systems. Physiol. Rev. 69:1989;1-32.
4. von Boehmer H., The H.S., Kisielow P. The thymus selects the useful, neglects the useless, and destroys the harmful. Immunol. Today. 10:1989;57-61.
5. Bonneau R.H., Sheridan J.F., Feng N., Glaser R. Stress-induced modulation of the primary cellular immune response to herpes simplex virus infection is mediated by both adrenal-dependent and independent mechanisms. J. Neuroimmunol. 42:1993;167-176.
6. Cannon J.G., Tatro J.B., Reichlin S., Dinarello C.A. Alpha melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1. J. Immunol. 1137:1986;2232-2236.
7. Compton M.M., Cidlowski J.A. Identification of a glucocorticoid-induced nuclease in thymocytes: a potential 'lysis gene'. J. Biol. Chem. 262:1987;8288-8292.
8. Compton M.M., Gibbs P.S., Swicegood L.R. Glucocorticoid-mediated activation of DNA degradation in avian lymphocytes. Gen. Comp. Endocrinol. 80:1990;68-79.
9. Compton M.M. A biochemical hallmark of apoptosis: internucleosomal degradation of the genome. Cancer Metastasis Rev. 11:1992;105-119.
10. Concordet J.P., Ferry A. Physiological programmed cell death in thymocytes is induced by physical stress (exercise). Am. J. Physiol. 265:1993;C626-C629.
11. Cupps T.R., Fauci A.S. Corticosteroid mediated immunoregulation in man. Immunol. Rev. 65:1982;133-155.
12. Dhabhar F.S., Miller A.H., Stein M., McEwen B.S., Spencer R.L. Diurnal and acute stress induced changes in distribution of peripheral blood leukocyte subpopulations. Brain Behav. Immun. 8:1994;66-79.
13. Dhabhar F.S., Miller A.H., McEwen B.S., Spencer R.L. Stress induced changes in blood leukocyte distribution, Role of adrenal steroid hormones. J. Immunol. 157:1996;1638-1644.
14. Felten D.L., Felten S.Y., Carlson S.L., Olschowka J.A., Livnat S. Noradrenergic and peptidergic innervation of lymphoid tissue. J. Immunol. 135:1985;755s-756s.
15. Glavin G.B., Pare W.P., Sandbak T., Bakke H.K., Murison R. Restraint Stress in Biomedical Research: An Update. Neurosci. Biobehav. Rev. 18:1994;223-249.
16. Griffin A.C., Lo W.D., Wolny A.C., Whitacre C.C. Suppression of experimental autoimmune encephalomyelitis by restraint stres: sex differences. J. Neuroimmunol. 44:1993;103-116.
17. Gruber J., Sgonc R., Hu Y.H., Beug H., Wick G. Thymocyte apoptosis induced by elevated endogenous corticosterone levels. Eur. J. Immunol. 24:1994;1115-1121.
18. Guidos C.J., Danska J.S., Fathman C.G., Weissman I.L. T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages. J. Exp. Med. 172:1990;835-845.
19. Hagan P., Poole S., Bristow A.F. Immunosuppressive activity of corticotropin releasing factor. Inhibition of interleukin 1 and interleukin 6 production by human mononuclear cells. Biochem. J. 281:1992;251-254.
20. Heagy W., Laurance M., Cohen E., Finberg R. Neurohormones regulate T cell function. J. Exp. Med. 17:1990;625-633.
21. Hori T., Fukuda M., Suzuki H., Yano S., Ono T. SART stress effects on lymphocytes in the thymus and spleen of normal, Adx, and sympathectomized mice. Clin. Immunol. Immunopathol. 68:1993;243-255.
22. Hori T., Katafuchi T., Take S., Shimizu N., Niijima A. The autonomic nervous system as a communication channel between the brain and the immune system. Neuroimmunomodulation. 2:1995;203-215.
23. Irwin M.R., Vale W., Britton K.T. Central corticotropin releasing factor suppresses natural killer cytotoxicity. Brain Behav. Immun. 1:1987;81-87.
24. Irwin M. Stress-induced immune suppression: role of brain corticotropic releasing hormone and autonomic nervous system mechanisms. Adv. Neuroimmunol. 4:1995;29-47.
25. Jain R., Zwickler D., Hollander C.S., Brand H., Saperstein A., Hutchinson B., Audhya T. Corticotropin releasing factor modulates the immune response to stress in the rat. Endocrinology. 128:1991;1329-1336.
26. Johnson H.M., Smith E.M., Torres B.A., Blalock J.E. Regulation of the in vitro antibody responses by neuroendocrine hormones. Proc. Natl. Acad. Sci. USA. 79:1982;4171-4174.
27. Jondal M., Okret S., McConkey D. Killing of immature CD4+CD8+ thymocytes in vivo by anti-CD3 or 5′-(N-ethyl)-carboxamido-adenosine is blocked by glucocorticoid receptor antagonist RU-486. Eur. J. Immunol. 23:1993;1246-1250.
28. Kawate T., Abo T., Hinuma S., Kumagai K. Studies on the bioperiodicity of the immune response. II. Co-variations of murine T and B cells and role of corticosteroid. J. Immunol. 126:1981;1364-1367.
29. Keller, S.E., Schleiffer, S.J., Demitrikopoulos, M.K., 1991. Stress induced changes in immune function in animals: hypothalamic pituitary adrenal influences. In: Ader, R., Cohen, N., Felten, D.I. (Eds.), Psychoneuroimmunology, 2nd ed. Academic Press, New York, pp. 778-788.
30. Leu S.J., Singh V.K. Modulation of natural killer cell mediated lysis by coricotropin releasing neurohormone. J. Neuroimmunol. 33:1991;253-260.
31. Leu S.J., Singh V.K. Stimulation of interleukin 6 production by corticotropin releasing factor. Cell. Immunol. 143:1992;220-227.
32. Livnat S., Felten S.Y., Carlson S.L., Belling D.L., Felten D.L. Involvement of peripheral and central catecholamine systems in neural-immune interactions. J. Neuroimmunol. 10:1985;5-30.
33. McGlone J.J., Lumpkin E.A., Norman R.L. Adrenocorticotropin stimulates natural killer cell activity. Endocrinology. 129:1991;1653-1658.
34. Nakamura K., Aoike A., Hosokawa T., Rokutan K., Koyama K., Nishi Y., Yoshida A., Kawai K. Effect of food-restriction stress on immune response in mice. J. Neuroimmunol. 30:1990;23-29.
35. Pare W.P., Glavin G.B. Restraint stress in biomedical research: A review. Neurosci. Biobehav. Rev. 10:1986;339-370.
36. Pepper G.M., Aggarwal K., Torres J., Velasco R., Dadhania K., Drake D., Futran J. The biologic activity of ACTH and related peptides on peripheral blood mononuclear cells is altered by the presence of dexamethasone. Cell. Immunol. 151:1993;110-117.
37. Reichlin S. Neuroendocrine-immune interactions. N. Engl. J. Med. 329:1993;1246-1253.
38. Rheins L.A., Cotleur A.L., Kleier R.S., Hoppenjans W.B., Saunder D.N., Nordlund J.J. Alpha melanocyte stimulating hormone modulates contact hypersensitivity responsiveness in C57BL6 mice. J. Invest. Dermatol. 93:1989;511-517.
39. Schwartzman R.A., Cidlowski J.A. Internucleosomal deoxyribonucleic acid cleavage activity in apoptotic thymocytes: detection and endocrine regulation. Endocrinology. 128:1991;1190-1197.
40. Sheridan J.F., Feng N.G., Bonneau R.H., Allen C.M., Huneycutt B.S., Glaser R. Restraint stress differentially affects anti viral cellular and humoral immune responses in mice. J. Neuroimmunol. 31:1991;245-255.
41. Stefano G.B., Cadet P., Scharrer B. Stimulatory effects of opioid neuropeptides on locomotory activity and conformational changes in invertebrate and human immunocytes: evidence for a subtype of δ receptor. Proc. Natl. Acad. Sci. USA. 86:1989;6307-6311.
42. Sun X.-M., Dinsdale D., Snowden R.T., Cohen G.M., Skilleter D.N. Characterization of apoptosis in thymocytes isolated from dexamethasone-treated rats. Biochem. Pharmacol. 44:1992;2131-2137.
43. Tarcic N., Levitan G., Ben-Yosef D., Prous D., Ovadia H., Weiss D.W. Restraint stress-induced changes in lymphocyte subsets and the expression of adhesion molecules. Neuroimmunomodulation. 2:1995;249-257.
44. Teshima H., Sogawa H., Kihara H., Nakagawa T. Influence of stress on the maturity of T-cells. Life Sciences. 49:1991;1571-1581.
45. Teshima H., Kihara H., Sogawa H., Irie M., Nakagawa T. Disturbances in the circadian rhythm of T cell subsets in stressed mice. Ann. N.Y. Acad. Sci. 650:1992;288-292.
46. Tsagarakis S., Grossman A. Corticotropin releasing hormone: interactions with the immune system. Neuroimmunomodulation. 1:1994;329-334.
47. Veljic J., Maric D., Jankovic B.D. Changes of experimental allergic encephalomyelitis by methionine enkephalin injected into lateral ventricles of the rat brain. Int. J. Neurosci. 59:1991;81-89.
48. Weidenfeld J., Abramsky O., Ovadia H. Effect of IL-1 on ACTH and corticosterone secretion in dexamethasone and Adx pretreated male rats. Neuroendocrinol. 50:1989;650-654.
49. Weigent D.A., Blalock J.E. Interactions between the neuroendocrine and immune systems: common hormones and receptors. Immunol. Rev. 100:1987;79-108.
50. Weiss J.M., Sundar S. Effects of stress on cellular immune responses in animals. Rev. Psychiatry. 11:1992;25-48.
51. Wyllie A.H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature. 284:1980;555-556.
52. Zacharchuk C.M., Mercep M., June C.H., Weissman A.M., Ashwell J.D. Variations in thymocyte susceptibility to clonal deletion during ontogeny, Implications for neonatal tolerance. J. Immunol. 147:1991;460-465.
53. Zwilling B.S., Brown D., Feng N., Sheridan J., Pearl D. The effect of adrenalectomy on the restraint stressed induced suppression of MHC class II expression by murine peritoneal macrophages. Brain Behav. Immun. 7:1993;29-35.