Neuroprotective effects of Buyang Huanwu Decoction on neuronal injury in hippocampus after transient forebrain ischemia in rats

Neuroscience Letters

Volumn 346, Issue 1-2, 2003, Pages 29-32

  Li, Xiao Ming ^a   Bai, Xiao Chun ^a   Qin, Lu Ning ^a   Huang, Hao ^a   Xiao, Zhong Ju ^a   Gao, Tian Ming ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Buyang Huanwu Decoction; Caspase 3; Hippocampus; Ischemia; Rat

Indexed keywords

BUYANG HUANWU EXTRACT; CASPASE 3; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; BUYANG HUANWU; CAROTID ARTERY OBSTRUCTION; CHINESE MEDICINE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME INHIBITION; HERB; HIPPOCAMPUS; MALE; NERVE CELL LESION; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES COMPARISON;

EID: 0038383786     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(03)00522-6     Document Type: Article

References (18)

1. Chan S.Q., Yan F., Xu D.J., Liu X.Y., Chen S.J. Studies on pharmacodynamics and acute toxicity of BuYangHuanWuTang granule. West China J. Pharm. Sci. 5:2000;259-261.
2. Chen J., Jin K., Chen M., Pei W., Kawaguchi K., Greenberg D.A., Simon R.P. Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death. J. Neurochem. 69:1997;232-245.
3. Chen J., Nagayama T., Jin K., Stetler R.A., Zhu R.L., Graham S.H., Simon R.P. Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. J. Neurosci. 18:1998;4914-4928.
4. Cheng Y.S., Cheng W.C., Yao C.H., Hsieh C.L., Lin J.G., Lai T.Y., Lin C.C., Tsai C.C. Effects of buyang huanwu decoction on peripheral nerve regeneration using silicone rubber chambers. Am. Chin. Med. 29:2001;423-432.
5. Deshmukh M., Vasilakos J., Deckwerth T.L., Lampe P.A., Shivers B.D., Johnson E.M. Jr. Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases. J. Cell Biol. 135:1996;1341-1354.
6. Du Y., Bales K.R., Dodel R.C., Hamilton-Byrd E., Horn J.W., Czilli D.L., Simmons L.K., Ni B., Paul S.M. Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons. Proc. Natl. Acad. Sci. USA. 94:1997;11657-11662.
7. Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:1992;493-501.
8. Hengartner M.O. The biochemistry of apoptosis. Nature. 407:2000;770-776.
9. Huang H., Gao T.M., Gong L., Zhuang Z., Li X.M. Potassium channel blocker TEA prevents CA1 hippocampal injury following transient forebrain ischemia in adult rats. Neurosci. Lett. 305:2001;83-86.
10. Kirino T., Tamura A., Sano K.A. Reversible type of neuronal injury following ischemia in the gerbil hippocampus. Stroke. 17:1986;455-459.
11. Lee J.M., Grabb M.C., Zipfel G.J., Choi D.W. Brain tissue responses to ischemia. J. Clin. Invest. 106:2000;723-731.
12. Namura S., Zhu J., Fink K., Endres M., Srinivasan A., Tomaselli K.J., Yuan J., Moskowitz M.A. Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J. Neurosci. 18:1998;3659-3668.
13. Pulsinelli W.A., Brierley J.B., Plum F. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke. 10:1979;267-272.
14. Qu H.D., Tong L., Shen J.G., Chen Y.Y. Protective effect of Buyanghuanwu Tang on cultured rat cortical neurons against hypoxia-induced apoptosis. Di Yi Jun Yi Da Xue Xue Bao. 22:2002;35-38.
15. Schulz J.B., Weller M., Klockgether T. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J. Neurosci. 16:1996;4696-4706.
16. Sugawara T., Noshita N., Lewen A., Gasche Y., Ferrand-Drake M., Fujimura M., Morita-Fujimura Y., Chan P.H. Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation. J. Neurosci. 22:2002;209-217.
17. Zeng Y.S., Xu Z.C. Co-existence of necrosis and apoptosis in rat hippocampus following transient forebrain ischemia. Neurosci. Res. 37:2000;113-125.
18. Zhang M.K., Yin L., Zhang X.W. Study headway of Buyang huanwu decoction on ischemia apoplexy. Chin. J. Basic Med. Trad. Chin. Med. 8:2002;74-79.